• Toxicological Research
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• 제25권1호
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• pp.9-15
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• 2009

Historically, research in toxicology has utilized non-human mammalian species, particularly rats and mice, to study in vivo the effects of toxic exposure on physiology and behavior. However, ethical considerations and the overwhelming increase in the number of chemicals to be screened has led to a shift away from in vivo work. The decline in in vivo experimentation has been accompanied by an increase in alternative methods for detecting and predicting detrimental effects: in vitro experimentation and in silico modeling. Yet, these new methodologies can not replace the need for in vivo work on animal physiology and behavior. The development of new, non-mammalian model systems shows great promise in restoring our ability to use behavioral endpoints in toxicological testing. Of these systems, the zebrafish, Danio rerio, is the model organism for which we are accumulating enough knowledge in vivo, in vitro, and in silico to enable us to develop a comprehensive, high-throughput toxicology screening system.

• 생물정신의학
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• 제30권1호
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• pp.7-16
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• 2023

Objectives This study aimed to review the Korean Constitution articles 14 and 20 of the "Law on suicide prevention" and investigate public perceptions of specific improvements to suicide prevention policies using results from the Korean 2018 National Survey on Suicide. Methods The questionnaire was designed to analyzing the act restricts sharing of patient information between hospitals, making it difficult to track suicide attempts. The questionnaire was also designed to suggest further medical and normative criteria for objective judgment of continuous follow-up utilizing suicide risk evaluations and proportional principle review that consider patients' and medical staff's basic rights. Results This study identified the result of the 1500 respondents, 79.1% believed that Korea should allow suicide prevention management to be implemented without requiring individual consent to protect suicide attempters. Conclusions According the results, I propose the following criteria for policy improvement: use of anonymized information and non-profit research for technical and ethical considerations, access to medical information only for therapeutic purposes, and use of surgical severity assessment criteria appropriate for Korea.

• Journal of Hospice and Palliative Care
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• 제25권4호
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• pp.139-197
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• 2022

Patients with terminal cancer experience very severe symptoms during the end of life, and palliative sedation (PS) may be considered if those symptoms are refractory to any other treatment. This brief report presents ethical considerations, practices, and recent concerns on PS. PS is quite different from euthanasia. There is a lack of consensus and standards on protocols, but its notable effects have been reported in hospice care settings. Most studies to date have reported no difference in survival between patients receiving PS and those not, and PS must be conducted proportionally with the lightest level of sedation. The most common indication for PS is delirium, and midazolam is the main sedative used. It is recommended that information regarding PS should be provided to patients and their caregivers repeatedly as early as possible. Existential suffering alone is not an indication for PS, and there is a lack of evidence on bispectral analysis. Additional research on PS is needed in Korea.

• International Journal of Advanced Culture Technology
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• 제11권4호
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• pp.56-61
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• 2023

The present study explored a comprehensive investigation of university professors' perspectives on the implementation of ChatGPT - an artificial intelligence-powered language model - in their teaching practices. A diverse group of 30 university professors responded to a questionnaire about the level of their interest in implementing the tool, willingness to apply it, and concerns they have regarding the intervention of ChatGPT in higher education setting. The results showed that the participants are highly interested in employing the tool into their teaching practice, and find that the students are likely to benefit from using ChatGPT in classroom settings. On the other hand, they displayed concerns regarding high depandency on data, privacy-related issues, lack of supports required, and technical contraints. In today's fast-paced society, educators are urged to mindfully apply this inevitable generative AI means with thoughtfulness and ethical considerations to and for their learners. Relevant topics are discussed to successfully intervene AI tools in teaching practices in higher education.

• 여성건강간호학회지
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• 제29권3호
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• pp.239-242
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• 2023

Artificial intelligence (AI) has tremendous potential to change the way we train future health professionals. Although AI can provide improved realism, engagement, and personalization in nursing simulations, it is also important to address any issues associated with the technology, teaching methods, and ethical considerations of AI. In nursing simulation education, AI does not replace the valuable role of nurse educators but can enhance the educational effectiveness of simulation by promoting interdisciplinary collaboration, faculty development, and learner self-direction. We should continue to explore, innovate, and adapt our teaching methods to provide nursing students with the best possible education.

• Clinical and Experimental Reproductive Medicine
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• 제51권1호
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• pp.1-12
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• 2024

This review article discusses the integration of artificial intelligence (AI) in assisted reproductive technology and provides key concepts to consider when introducing AI systems into reproductive medicine practices. The article highlights the various applications of AI in reproductive medicine and discusses whether to use commercial or in-house AI systems. This review also provides criteria for implementing new AI systems in the laboratory and discusses the factors that should be considered when introducing AI in the laboratory, including the user interface, scalability, training, support, follow-up, cost, ethics, and data quality. The article emphasises the importance of ethical considerations, data quality, and continuous algorithm updates to ensure the accuracy and safety of AI systems.

• 한국의료윤리학회지
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• 제21권4호
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• pp.330-343
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• 2018

4차 산업혁명시대가 도래했다는 관심이 증가되면서 이에 따른 윤리적 이슈에 대한 탐구 및 대학 교육의 방향에 대한 제고가 필요하게 되었다. 본 논문의 목적은 4차 산업혁명 시대의 대표적 기술분야인 인공지능, 빅데이터, 유전체 기술, 가상현실의 윤리적 이슈 및 국내외 정책과 교육 현황을 살펴보고 앞으로 대학의 생명윤리교육이 나아가야 할 방향을 제안하는 것이다. 4차 산업혁명시대의 국내외 정책과 교육현황을 요약하면, 국외는 4차 산업혁명 기술의 잠재적 이득과 사회적 위험에 대한 법적, 윤리적 고려를 바탕으로 관련 가이드 라인 및 규제 권고안이 발표되었고, 과학 기술의 발전에 따른 학생들의 윤리적 가치 확립의 중요성이 정책적으로 강조됨에 따라 4차 산업혁명시대의 기술개발과 관련된 생명윤리교육과정이 개설된 바 있으며, 대학 내 윤리실험실 개설, 공개 토론회를 넘어 온라인 공개 강좌를 통해 생명윤리 교육의 접근성을 높이고 있다. 국내의 경우에도 최근 공청회 등을 통해 4차 산업시대의 정책방향에 대한 논의가 이루어지고 있으며, 대학교육 또한 시대적 흐름에 맞는 생명윤리 교육을 제공하기 위한 시도가 이루어지고 있다. 그러나 국내 대학의 생명윤리교육은 전통적인 생명윤리 주제에 새로운 과학기술로 야기된 윤리적 이슈를 일부 추가하여 운영되는 교육과정이 대부분이며, 단일 전공 교수자의 강의 운영, 선택 과목, 비정기적인 강의 개설, 그리고 온라인 공개 강좌의 부재 등의 제한점이 확인되었다. 이에 따라, 본 논문에서는 추후 국내 대학의 생명윤리교육을 개선하기 위한 방안을 다음과 같이 제안하고자 한다; 국내 대학의 생명윤리교육은 다직군 간 교육으로 개발되고, 점진적으로 필수 교육과정으로 지정하여 교육의 기회를 확보하며, 온라인 공개 강좌로 확대 개설할 필요가 있다. 또한, 대학 내 생명윤리 이슈에 관한 공개 토론의 장을 마련하고 과학기술의 발전과 그 변화를 함께할 수 있도록 주기적인 논의를 통해 생명윤리교육의 내용을 지속적으로 개선해야 할 것이다.

• Journal of Genetic Medicine
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• 제4권1호
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• pp.1-5
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• 2007

Unprecedented amount of genetic information being generated from the result of Human Genome Project (HGP) and advances in genetic research is already forcing changes in the paradigm of health and disease. The ultimate goal of genetic medicine is to use genetic information and technology to develop new ways of treatment or even prevention of the disease on an individual level for 'personalized medicine'. Genetics is play ing an increasingly important role in the diagnosis, monitoring and management of common multifactorial diseases in addition to rare single-gene disorders. While wide range of genetic testing have provided benefits to patients and family, uncertainties surrounding test interpretation, the current lack of available medical options for the diseases, and risks for discrimination and social stigmatization may remain to be resolved. However an increasing number of genetic tests are becoming commercially available, including direct to consumer genetic testing, yet public is often unaw are of their clinical and social implications. The personal nature of information generated by a genetic test, its power to affect major life decisions and family members, and its potential misuse raise important ethical considerations. Therefore appropriate genetic counseling is needed for patient to be informed with the benefits, limitations and risks of genetic tests, prior to informed consent for the tests. Physician also should be familiar with the legal and ethical issues involved in genetic testing to tell patients how w ell a particular genetic risk factor relates with likelihood of disease, and be able to provide appropriate genetic counseling. Genetic counseling become a mandatory requirement as global standard for many genetic testing such as prenatal diagnosis, presymtomatic DNA diagnostic tests and cancer susceptibility gene test for familial cancer syndrome. In oder to meet the challenge of genetic medicine of 21 century in korean health care system, professional education program and certification board for medical genetics specialist including non-MD genetic counselors should be addressed by medical society and regulatory policy of national health insurance reimbursement for genetic counseling to be in place to promote the implementation of clinical genetic service including genetic counseling for proper genetic testing.

• 한국과학교육학회지
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• 제44권2호
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• pp.209-217
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• 2024

본 연구의 목적은 2015 개정 교육과정의 생명과학II와 공학일반의 생명공학기술 관련 학습 내용을 분석하고 생명공학기술 교육을 위한 교육적 시사점을 제공하고자 하였다. 연구 결과는 다음과 같다. 첫번째, 생명과학II의 학습 주제는 생명공학기술과 관련된 윤리적인측면에 초점을 두고 있는 반면, 공학일반의 학습 주제는 끊임없이 발달하는 생명공학기술의 산업적인 측면에 초점을 두고 있었다. 두번째, 생명과학II 교과서와 공학일반 교과서는 서로 중복된 생명공학기술을 다루고 있으며, 생명과학II 교과서는 공학일반 교과서보다 생명공학기술의 원리를 보다 과학적이고 전문적으로 진술하고 있으며, 생명공학기술에 대한 전반적인 설명이 더 구체적이다. 또한 공학일반 교과서는 생명공학기술에 대한 윤리적인 접근을 등한시하고, 한국에서 금지하고 있는 생식세포 유전자 치료를 다루고 있었다. 이러한 결과는 이러한 생명공학기술 내용이 각 학교의 교육과정과 학생특성에 따른 재구성이 필요함을 시사한다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.4961-4964
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• 2013

Greater use of mobile phone devices seems inevitable because the health industry and cancer care are facing challenges such as resource constraints, rising care costs, the need for immediate access to healthcare data of types such as audio video texts for early detection and treatment of patients and increasing remote aids in telemedicine. Physicians, in order to study the causes of cancer, detect cancer earlier, act in prevention measures, determine the effectiveness of treatment and specify the reasons for the treatment ineffectiveness, need to access accurate, comprehensive and timely cancer data. Mobile devices provide opportunities and can play an important role in consulting, diagnosis, treatment, and quick access to health information. There easy carriage make them perfect tools for healthcare providers in cancer care management. Key factors in cancer care management systems through a mobile phone health approach must be considered such as human resources, confidentiality and privacy, legal and ethical issues, appropriate ICT and provider infrastructure and costs in general aspects and interoperability, human relationships, types of mobile devices and telecommunication related points in specific aspects. The successful implementation of mobile-based systems in cancer care management will constantly face many challenges. Hence, in applying mobile cancer care, involvement of users and considering their needs in all phases of project, providing adequate bandwidth, preparation of standard tools that provide maximum mobility and flexibility for users, decreasing obstacles to interrupt network communications, and using suitable communication protocols are essential. It is obvious that identifying and reducing barriers and strengthening the positive points will have a significant role in appropriate planning and promoting the achievements of mobile cancer care systems. The aim of this article is to explain key points which should be considered in designing appropriate mobile health systems in cancer care as an approach for improving cancer care management.