• 약학회지
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• 제46권5호
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• pp.343-347
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• 2002

In the present study, effects of essential oils isolated from various plants have been evaluated on lipopolysaccharide (LPS)-induced release of nitric oxide (NO), prostaglandin E$_2$(PGE$_2$) and tumor necrosis factor-a (TNF-$\alpha$) by the macrophage RAW 264.7 cells. Among the tested essential oils, essential oil of Ligularia fischeri var. spiciformis (LF-oil) significantly inhibited the LPS-induced generation of NO, PGE$_2$ and TNF-$\alpha$ in Raw 264.7 cells. Consistent with these observations, the expression of inducible NO synthase (iNOS) and cyclooxygenase (COX)-2 enzyme was inhibited by LF-oil in a concentration-dependent manner. Thus, this study suggests that inhibition of release of iNOS, COX-2 expression, and TNF-$\alpha$ by the essential oil of Ligularia fischer may be one of the mechanisms responsible for the anti-inflammatory effects of this medicinal plant.

• Preventive Nutrition and Food Science
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• 제11권3호
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• pp.232-236
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• 2006

The essential oil of Swertia chirata Buch.-Ham. was extracted by solvent extraction (n-pentane:diethylether, 1:1) method using simultaneous distillation-extraction (SDE) apparatus and analyzed by gas chromatography-mass spectrometry (GC/MS). The yield of essential oil obtained from S. chirata was 236.47 mg/kg. Seventy seven compounds of the essential oil belonging to chemical classes of acid (4), alcohol (21), aldehyde (15), ester (3), furan (3), hydrocarbon (7), ketone (17) and miscellaneous (7) were tentatively identified. The major volatile compounds ranged in content order were as follows: undecanoic acid (28.63%), 2-buten-2-one (20.42%), camphor (18.40%), 2-heptadecanone (14.72%), and cedrol (13.07%).

• 식품보건융합연구
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• 제6권3호
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• pp.5-21
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• 2020

Bungkang (Syzygium polyanthum) is a medium to tall plant which produces medicinal root-bark, the plant is normally found along inland river bank and produces small white flowers and fruits. Essential oils are among the most interesting components of the plant extracts consisting mostly of monoterpenoid or sesquiterpenoids. They are used as therapeutic agents in ethno, conventional, and complementary alternative medicines. Investigation and evaluation of the essential oil of Syzygium polyanthum as well as the antibacterial, antioxidant and antifungal activity was ascertained. The experiment was performed. 100 chemical constituents were obtained and two pure compound was isolated as Eugenol (1) and Farnesol (2). Significant growth inhibition of Staphylococcus aureus, (ATCCⓒ25923) Klebsiellia pneumonia (ATCCⓒ19155), Salmonella typhi (ATCCⓒ14028) and Escherichia coli (ATCC©25922) and the fungal strains Aspergillus flavin, Aspergillus niger, Candida, tropicalis, and Fusarium oxysporium was observed from the essential oil at concentration of 500 ㎍/mL. Antioxidant potential was observed to be strong of 18.42 ㎍/mL when compared to the control of 15.23 ㎍/mL. The result indicated that the oil obtained from root-bark of Syzygium polyanthum can be considered as an agent for antioxidant, antibacterial and antifungal in pharmaceutical food and cosmetic industries trails.

• 한국식품영양학회지
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• 제35권3호
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• pp.185-192
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• 2022

This study investigated the volatile flavor components of the essential oil from Chrysanthemum coronarium var. spatiosumBailey. The essential oil obtained from the aerial parts of the plant by the hydrodistillation extraction method was analyzed by gas chromatography and gas chromatography-mass spectrometry. One hundred and one (99.11%) volatile flavor components were identified in the essential oil from the Chrysanthemum coronarium var. spatiosum Bailey. The major compounds were hexanedioic acid, bis(2-ethylhexyl) ester (12.45%), 6.10.14-trimethyl-2-pentadecanone (7.94%), 1-(phenylethynyl)-1-cyclohexanol (6.34%), α-farnesene (5.55%), phytol (4.99%), and α-caryophyllene (4.39%). When the volatile flavor components of Chrysanthemum coronarium var. spatiosum Bailey were classified by functional group, the content was high in the order of hydrocarbons, alcohols, esters, ketones, aldehydes, and phthalides. Sesquiterpene hydrocarbons were the most common hydrocarbons, mainly due to α-farnesene and α-caryophyllene. Among the alcohols, the content of aliphatic alcohols was significantly higher, mainly due to 1-(phenylethnyl)-1-cyclohexanol (6.34%) and phytol (4.99%). The analysis of the volatile flavor components of Chrysanthemum coronarium var. spatiosum Bailey in this study will provide useful information to consumers when purchasing food and to industries using fragrance ingredients.

• Parasites, Hosts and Diseases
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• 제62권2호
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• pp.217-225
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• 2024

This study evaluated the potential repellent and acaricidal effects of 4 essential oils (clove, eucalyptus, lavender, and mint) against the Asian longhorned tick Haemaphysalis longicornis, a vector of various tick-borne diseases in medical and veterinary contexts. Selected for their potential repellent and acaricidal properties, the 4 essential oils were tested on adult and nymph H. longicornis ticks at different concentrations. The experiment assessed mortality rates and repellency, particularly during tick attachment to host skin. There was a significant increase (P<0.05) in tick mortality and repellency scores across all groups. At a 1% concentration, adult tick mortality ranged from 36% to 86%, while nymph mortality ranged from 6% to 97%. Clove oil exhibited notable efficacy, demonstrating high mortality rates of nymphs and adults. Clove oil also displayed strong repellency properties, with a repellency index of 0.05, surpassing those of mint, eucalyptus, and lavender oils. Clove oil showed the highest effectiveness in deterring nonattached adult ticks (90%) and nymphs (95%) when applied to skin. Clove oil was the most effective against adult and nymph ticks, achieving mortality rates of 86% and 97%, respectively, and led to the highest nonattachment rates when applied to skin. In conclusion, essential oils such as clove, eucalyptus, lavender, and mint oils present promising results for tick population control.

• 생명과학회지
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• 제27권6호
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• pp.646-651
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• 2017

본 연구는 소나무 부위별 추출물을 피부염 유발 균주에 적용함으로써 항균 및 항진균 활성을 측정하고 그 결과를 보고하고자 하였다. 먼저 paper disc 법을 이용하여 항균 및 항진균 실험에서 송엽, 송절 및 송화 에탄올 추출물은 대부분의 피부염 균주에 대하여 항균활성을 나타내었으나, 물 추출물은 모든 피부염 균주에 대하여 항균활성을 나타내지 않았다. 송엽 및 송절 70% 에탄올 추출물이 T. rubrum을 제외한 모든 피부염 균주에 대하여 항균활성을 나타내었으며, 송화 70% 에탄올 추출물은 C. tropicalis와 P. acens에 대해서만 항균활성을 보였다. 소나무 essential oil의 항균 및 항진균 활성을 측정한 결과, C. albicans, C. tropicalis, T. rubrum에 대해 1.5~3 mm 정도의 생육저해환을 형성하여 높은 항진균 활성을 나타내었다. 이러한 결과를 바탕으로 소나무 부위별 70% 에탄올 추출물에 활성을 나타내었던 피부염 관련 균주 6종에 대한 최소생육 저해 농도를 측정한 결과, 송엽 70% 에탄올 추출물은 C. tropicalis 및 P. acnes에 대하여 0.002%와 0.0063%의 낮은 농도에서 항균효과가 나타났고 송절 70% 에탄올 추출물은 0.003% 농도에서 P. acnes의 생육을 억제하여 뛰어난 효과를 보였다. 소나무 essential oil의 최소생육 저해 농도를 측정한 결과, 0.025% 농도에서 C. albicans와 C. tropicalis의 생육을 효과적으로 억제하는 것으로 나타났다. 송엽 essential oil은 C. albicans, C. tropicalis, T. rubrum에 대해 항진균 효과가 있는 것으로 확인되었다. 이상의 결과를 통해 소나무 부위 중 송엽과 송절 70% 에탄올 추출물에서 항균 및 항진균 효과가 뛰어났으며, 특히, 송절 70% 에탄올 추출물이 S. aureus, S. epidermidis, P. acnes에 대해 더 높은 항균 효과를 나타내었다. 따라서, 소나무 송절과 송엽 에탄올 추출물과 essential oil은 Candida 속과 P. acnes에 대한 억제효과가 크게 나타나 이와 관련한 피부질환 개선에 효과가 클 것으로 사료된다.

• 동의생리병리학회지
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• 제21권2호
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• pp.528-531
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• 2007

Artemisia vulgaris essential oil exhibited a strong metal chelating activity but withlow reducing power, and radical scavenging activity. However, a gradual increase in the radical scavenging activity was obtained with increasing concentration and reaction time.

• 생약학회지
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• 제26권2호
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• pp.164-167
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• 1995

The essential oils from the roots of Codonopsis lanceolata and the cultivated callus were analysed and compared by gaschromatography-mass spectrometry. In the experimental study of cell culture, it appeared that 2,4-dichlorophenoxy acetic acid in the culture medium induced higher production of essential oils in the callus than indole acetic acid. The growth of callus was inhibited by illumination of the light. The production of essential oil in cultured cells was increased by the addition of biosynthetic precursors. The essential oils from the roots of Codonopsis lanceolata and the cultured callus showed different compositions. Tetradecanoic acid, 1,1,-dimethoxyl 4-methoxy phenol, 9,12-octadecanoic acid and hexadecanoic acid were identified as main components of the cultured callus oil.

• Mycobiology
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• 제37권1호
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• pp.67-68
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• 2009

Antifungal activity of celery essential oil against Malassezia furfur was investigated using broth microdilution and vapor contact methods. Potent antifungal activity was evident using both methods. Fungicidal activity was revealed in the vapor contact method.

• 대한통합의학회지
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• 제6권3호
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• pp.131-139
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• 2018

Purpose : The study objective was to assess the antibacterial activity of essential oil of basil against S. mutans and P. gingivalis and to explore its potential to prevent dental caries and peridontal disease. Method : Essential oil of basil, extracted using steam distillation, was diluted with triple distilled water and Tween 20 to generate samples at various concentration, that is 30%, 50%, and 70% (v/v). Strains of S. mutans and P. gingivalis were incubated in the medium under anaerobic condition. Broth microdilution susceptibility testing and plate incubation diffusion were utilized to determine the minimum inhibitory concentration (MIC) and to measure antibacterial activity, respectively. Result : An upsurge in antibacterial activity was seen to correlate with and increase in the concentration used for both bacterial strains, but was more significant with S. mutans. A statistically significant growth inhibition effect and reduction in the number of colonies was also observed with both strains dependent on the concentration used following 24 hours of incubation. Conclusion : Thus, the current study finding was that essential oil of basil was effective against dental caries and periodontal disease and could be used in dentifrice to help prevent oral disease.