• The Journal of Korean Academy of Sensory Integration
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• v.19 no.3
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• pp.22-31
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• 2021

Purpose : This study aimed to conduct a translation, backtranslation, and content validity test of the Sensory Processing Measure (SPM) for Korean children. Methods : The translation and content validation process involved direct and backward translation; a test of equivalence between the two versions (the original SPM and the Korean version SPM; K-SPM) was performed using content-related evidence collected by a group of experts and a group of parents. Data analysis was carried out using Excel Content validity indices (CVI), mean, and standard deviation were used for the analysis of content validity. Results : The result of the comparison between the original SPM and K-SPM in the group of experts was 3.54 ± .74, the S-CVI/Avg for semanticity was .92, and the S-CVI/Avg for structure was .86. The results for the mean of the understanding test and the S-CVI/Avg were 3.48 ± .63 and .94, respectively. Conclusion : K-SPM will considerately be used as an assessment to identify sensory processing, praxis, and social participation issues for children in Korea. Further studies are suggested to increase the age range and the sample size for a more comprehensive applicability of the K-SPM to Korean children.

• The Mathematical Education
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• v.37 no.1
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• pp.1-13
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• 1998

In this paper, we have represented the efficient way how to enumerate the optimal number-right scores to adjust the item difficulty and to improve item discrimination. To estimate the optimal number-right scores in two equivalent math-tests by linear score equating a measurement error model was applied to the true scores observed from a pair of equivalent math-tests assumed to measure same trait. The model specification for true scores which is represented by the bivariate model is a simple regression model to inference the optimal number-right scores and we assume again that the two simple regression lines of raw scores and true scores are independent each other in their error models. We enumerated the difference between mean value of $\chi$＊ and ${\mu}$$\_$$\chi$/ and the difference between the mean value of y＊and a＋b${\mu}$$\_$$\chi$/ by making an inference the estimates from 2 error variable regression model. Furthermore, so as to distinguish from the original score points, the estimated number-right scores y’$\^$*/ as the estimated regression values of true scores with the same coordinate were moved to center points that were composed of such difference values with result of such parallel score moving procedure as above mentioned. We got the asymptotically normal distribution in Figure 5 that was represented as the optimal distribution of the optimal number-right scores so that we could decide the optimal proportion of number-right score in each item. Also by assumption that equivalence of two tests is closely connected to unidimensionality of a student’s ability. we introduce new definition of trait score to evaluate such ability in each item. In this study there are much limitations in getting the real true scores and in analyzing data of the bivariate error model. However, even with these limitations we believe that this study indicates that the estimation of optimal number right scores by using this enumeration procedure could be easily achieved.

• Korean Journal of Clinical Pharmacy
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• v.7 no.1
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• pp.17-21
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• 1997

Cefaclor is a second generation cephalosporin antibiotic that shows a potent antibacterial activity against both Gram-positive and Gram-negative bacteria, when it is orally administered. Due to its patent expiration, a number of generic drugs have been marketed, but not yet elucidated to ensure therapeutic equivalence. In this study, cefaclor capsules manufactured by Chong Kun Dang were bioequivallently assessed by comparing with $Ceclor^{TM}$ introduced originally by Daewoong Lilly. A total of 16 healthy male volunteers were evaluated in a randomized crossover manner with a 2-week washout period. Concentrations of cefaclor in plasma were measured upto 6 hours following a single oral administration of two capsules (500 mg of cefaclor) by high-performance liquid chromatography with UV detection. Although the plasma concentration at 6 hours was not detected, the computed half-life of cefaclor was approximately 0.5 hours. The area under the concentration-vs-time curve from 0 to 4 hours $(AUC_{0-4h})$ was calculated by the trapezoidal summation method. The differences in mean values of $AUC_{0-4h}$, peak plasma concentration $(C_{max})$, and time to peak concentration $(T_{max})$ between the two products were $4.63\%,\;1.84\%,\;and\3.28\%$, respectively. The least significant differences at $\alpha4= 0.05 for $AUC_{0-4h},\;C_{max},\;and\;T_{max}\;were\;6,53\%,\;4.05\%,\;and\;6.47\%$, respectively. In conclusion, the test drug was bioequivalent with the reference drug.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2011.11a
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• pp.441-444
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• 2011

Type A and Type B and are commercial HTPB models, which are very popular prepolymer for polyurethane binder family. So the study has been performed on the physical, chemical characteristic of HTPB and viscosity, mechanical property of PBX-A applying to HTPB. But We excluded the Type A from Appication test, because of law Hydroxyl value. And in the case of Type B, Type B-1, 2 has mechanical disadvatage to apply to HTPB in the process comparing with B-3. It seems to make no problem if we change equivalence ratio or curing condition within standards. But if we are to apply process condition like R-45HT(US-sample), it would be essential to apply HTPB with higher Hydroxyl Value and hydroxyl Functionality.

• Journal of Satellite, Information and Communications
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• v.8 no.3
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• pp.1-5
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• 2013

In this paper, we present a conversion algorithm of the oblique ionogram obtained from Jeju and Icheon to the equivalent vertical ionogram of the path mid-point, based on some equivalence theorems between the vertical sounding and the oblique sounding for the ionosphere. And in order to verify the conversion algorithm under the condition of no vertical ionosonde at the mid-point on the test path, the equivalent vertical ionograms are compared to the real vertical ionograms measured adjacently in space-time. The comparison results show that the conversion algorithm performs well for the short-path oblique ionogram and the equivalent vertical ionograms could be applied to get the electron density profiles at the mid-point.

• Journal of Korean Academy of Nursing Administration
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• v.4 no.1
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• pp.33-71
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• 1998

본 연구의 목적은 한국의 간호사들이 행하는 간호중재를 규명하는 것이다. 연구대상은 한국의 2 병원에서 일하는 수 간호사와 평 간호사를 포함한 443면의 간호사이며, 연구도구는 Iowa Intervention Project Team 이 개발한 336 문항의 5점 척도로 이루어진 "간호중재"설문지를 사용하였다. 5점 척도는 다음과 같다 : (a) 거의 행하지 않는다 : (b) 거의 한달에 한번 행한다 : (c) 거의 일주일에 한 번 행한다 : (d) 거의 하루에 한 번 행한다 : (e) 하루에 여러 번 행한다. 한국자료를 위해 설문지는 본 연구자에 의해 한글로 번역되었고, Back-translation을 이용하여 한글로 번역한 설문지는 다시 bilingual nurse에 의해 영어로 옮겨졌고, 마지막으로 영어로 옮겨진 설문지를 원래의 영문으로 된 설문지와 비교한 후에(Equivalence Test) 수정${\cdot}$보완하여 사용하였다. 한국 간호사들은 336 간호중재 모두를 행하고 있으며, 21개의 간호중재가 적어도 하루에 한 번 정도는 이루어지고 있었다. 간호사들은 "생리적 : 복합영역"에 속하는 간호중재를 가장 빈번하게 행하였고, 이 중에서 "비경구적 투약"은 일주일에 거의 11번 정도로 가장 많이 행하여졌다. 가장 적게 행하는 간호중재는 "동물이용요법"이었다. 간호사들은 교육을 많이 받을수록, 임상경험이 많을수록 더 많은 간호중재를 빈번하게 행했다. 특히, 석사학위를 받은 간호사는 "행위 영역"에 속한 간호중재를 더 많이 행했는 데, 예를 들면 "적극적 경청", "적응 증진", "의사결정지지"등이다. 또한 4년제 대학을 졸업한 간호사들은 "생리적 : 복합영역"에 속한 간호중재들을 전문대학을 졸업한 간호사보다 더 많이 행했는 데, 예를 들면, "뇌부종 관리", "반사 장애 관리", "기구를 사용한 호흡"등이다. 10년 이상의 경험을 가진 간호사들은 "행위 영역"에 속한 간호중재를 임상 경험이 1년 미만이거나 또는 1-5년 사이의 경험을 가진 간호사보다 더 많이 행했는 데, 예를 들면, "죄책감 극복 증진", "진실 말하기"등이다. 또한 6-10년 사이의 임상경험을 가진 간호사들은 "자가 간호영역"에 속한 "옷 입히기", "두발 간호", "구강건강 유지" 등을 임상경험이 1년 미만인 간호사들보다 더 빈번하게 행했다. 이 연구는 간호중재 규명이 간호원가 산출을 위한 연구와, 간호의 질 향상을 위한 연구, 간호지식 탐구를 위한 연구에 공헌할 것을 기대한다.

• Journal of Korean Academy of Nursing
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• v.42 no.7
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• pp.974-983
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• 2012

Purpose: The purpose of this study was to translate the Spiritual Perspective Scale (SPS) and Self-transcendence Scale (STS) into Korean and test the psychometric properties of the instruments with Korean elders. Methods: A cross-sectional survey design was used to implement the three stages of the study. Stage I consisted of translating and reviewing the scales by six experts. In Stage II, equivalence was tested by comparing the responses between the Korean and English versions among 71 bilingual adults. Stage III established the psychometric properties of the Korean versions SPS-K and STS-K among 154 Korean elders. Results: Cronbach's alpha of the SPS-K and the STS-K .97, and .85 respectively with Korean elders. Factor analysis showed that the SPS-K had one factor; the STS-K had four factors with one factor clearly representing self-transcendence as theorized. Both scales showed good reliability and validity for the translated Korean versions. However, continued study of the construct validity of the STS-K is needed. Conclusion: Study findings indicate that the SPS-K and the STS-K could be useful for nurses and geriatric researchers to assess a broadly defined spirituality, and to conduct research on spirituality and health among Korean elders. Use of these scales within a theory-based study may contribute to further knowledge about the role of spirituality in the health and well-being of Korean people facing health crises.

• BMB Reports
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• v.53 no.8
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• pp.437-441
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• 2020

In accordance with requirements of the ICH S7B safety pharmacology guidelines, numerous next-generation cardiotoxicity studies using human stem cell-derived cardiomyocytes (CMs) are being conducted globally. Although several stem cell-derived CMs are being developed for commercialization, there is insufficient research to verify if these CMs can replace animal experiments. In this study, in vitro high-efficiency CMs derived from human embryonic stem cells (hESC-CMs) were compared with Sprague-Dawley rats as in vivo experimental animals, and primary cultured in vitro rat-CMs for cardiotoxicity tests. In vivo rats were administrated with two consecutive injections of 100 mg/kg isoproterenol, 15 mg/kg doxorubicin, or 100 mg/kg nifedipine, while in vitro rat-CMs and hESC-CMs were treated with 5 μM isoproterenol, 5 μM doxorubicin, and 50 μM nifedipine. We have verified the equivalence of hESC-CMs assessments over various molecular biological markers, morphological analysis. Also, we have identified the advantages of hESC-CMs, which can distinguish between species variability, over electrophysiological analysis of ion channels against cardiac damage. Our findings demonstrate the possibility and advantage of high-efficiency hESC-CMs as next-generation cardiotoxicity assessment.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.36 no.2
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• pp.225-232
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• 2012

A chemical reactor network (CRN) was developed for a lean premixed gas turbine combustor to predict the emission of pollutants such as NOx and CO. In this study, the predictions of NOx and CO emissions from lean premixed methane-air combustion in the gas turbine were carried out using CHEMKIN and a GRI 3.0 methane-air combustion mechanism, which includes the four NO formation mechanisms for various load conditions. The calculated results were compared with experimental data obtained from a modified test combustor to validate the model. The contributions of the four NO pathways were investigated for various load conditions. The effects of nonuniformity of the mass flux and of the equivalence ratio of the injector on the NOx formation were investigated, and a method of reducing the pollutant formation was suggested for the development of a sub-10 ppm gas turbine combustor.

• Journal of Plant Biotechnology
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• v.35 no.1
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• pp.13-21
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• 2008

Final regulatory steps for commercialization of transgenic crops are risk assessment and variety registration. The risk assessment of transgenic crops requires broad network of scientists, high cost and long term. Developers of transgenic crops, therefore, face to additional challenges to consider theoretical and strategic aspects on risk assessment. The general concept for risk assessment of genetically modified organisms was derived from chemical risk assessment. Due to the complexity of organisms, however, comparative approaches that are substantial equivalence and familarity have been developed. In practical view, the integration of risk assessment is more difficult than the evaluation of each risk factors involving gene flow, toxicity and allergenicity. Variety registration of transgenic crops requires the results of risk assessment compared with non-GM crops and agronomic data analyzed with standard varieties. For economic and fast commercialization, risk assessment process should combined with condition of cultivation test for variety registration.