• Title/Summary/Keyword: epifriedelanol

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Antitumor and Antiinflammatory Constituents from Celtis sinensis

  • Kim Dae Keun;Lim Jong Pil;Kim Jin Wook;Park Hee Wook;Eun Jae Soon
    • Archives of Pharmacal Research
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    • v.28 no.1
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    • pp.39-43
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    • 2005
  • Eight compounds were isolated from the methanolic extract of the twigs of Celtis sinensis through repeated silica gel and Sephadex LH-20 column chromatography. Their chemical structures were elucidated as two triterpenoids, germanicol and epifriedelanol, two amide compounds, trans-N-caffeoyltyramine and cis-N-coumaroyltyramine, two lignan glycoside, pinoresinol glycoside and pinoresinol rutinoside, and two steroids by spectroscopic analysis.

Pentacyclic Triterpenoids from Mallotus apelta

  • Kiem, Phan-Van;Minh, Chau-Van;Huong, Hoang-Thanh;Nam, Nguyen-Hoai;Lee, Jung-Joon;Kim, Young-Ho
    • Archives of Pharmacal Research
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    • v.27 no.11
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    • pp.1109-1113
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    • 2004
  • A new triterpene (1) and six known pentacyclic terpenoids (2-7) were isolated from the methanol extract of the dried leaves from Mallotus apelta. Based on the spectral and chemical evidence, their structures were determined to be 3$\alpha$-hydroxyhop-22(29)-ene (1), hennadiol (2), friedelin (3), friedelanol (4), epifriedelanol (5), taraxerone (6), and epitaraxerol (7).

Cyclooxgenase Inhibitory Components from Portulaca oleracea

  • Kim, Jeong-Ah;Yang, Seo-Young;Kang, Sang-Jin;Kim, Young-Ho
    • Natural Product Sciences
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    • v.18 no.1
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    • pp.22-25
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    • 2012
  • Five triterpenoids, epifriedelanol (1), friedelin (2), lupeol (3), ${\beta}$-sitosterol (4), daucosterol (5), and one phenyl propanoids ester, trans-docosanoyl ferulate (6) were isolated from the whole parts of Portulaca oleracea. They were determined using a combination of spectroscopic analyses ($^1H-$, $^{13}C$-NMR, and MS data) and evaluated for their cyclooxygenase inhibitory activity. Compound 6 exhibited inhibitory effect with $IC_{50}$ values of $40.2{\mu}M$ and 1.6 mM on COX-1 and COX-2 activities, respectively.