• 생물정신의학
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• 제15권4호
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• pp.243-253
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• 2008

In the post-genomic era, the mechanisms controlling activation of genes are thought to be more important. Gene-environment interactions are crucial in both development and treatment of psychiatric disorders as they are complex genetic disorders. Epigenetics is defined as a change of gene expression that occurs without a change of DNA sequence and can be heritable by certain mechanisms. Epigenetic changes play essential roles in control of gene activation. DNA methylation, chromatin remodeling and RNAi act as key mechanisms for epigenetic modifications of genes. Here, we review the basic mechanisms of epigenetics and discuss their potential involvement of human diseases, including psychiatric disorders.

• Asia pacific journal of information systems
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• 제5권2호
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• pp.259-288
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• 1995

Using end-user attitude as intervening variable, this paper proposes a causal model of how environmental factors of EUC influence end-user computing (EUC) success, measured by the degree of IS use. This study identifies unique aspects of the EUC environment and generates key dimensions of end-user attitude appropriate for this context : perceived information quality, perceived design quality, and perceived usefulness. The research model includes six environmental factors - top management support, end-user education, task variability, task analyzability, end-user's computing ability, and end-user involvement. A field study was undertaken to test the hypothesized relationships among the research variables. The results generally support the assumption that end-user attitude intervene the impact of environmental factors on IS use. The implications of the findings are discussed.

• Journal of Microbiology and Biotechnology
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• 제20권11호
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• pp.1571-1576
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• 2010

Two bacterial strains designated as CT2 and CT5 were isolated from highly alkaline cement samples using the enrichment culture technique. On the basis of various physiological tests and 16S rRNA sequence analysis, the bacteria were identified as Bacillus species. The urease production was 575.87 U/ml and 670.71 U/ml for CT2 and CT5, respectively. Calcite constituted 27.6% and 31% of the total weight of sand samples plugged by CT2 and CT5, respectively. Scanning electron micrography analysis revealed the direct involvement of these isolates in calcite precipitation. This is the first report of the isolation and identification of Bacillus species from cement. Based on the ability of these bacteria to tolerate the extreme environment of cement, they have potential to be used in remediating the cracks and fissures in various building or concrete structures.

• 대한안전경영과학회지
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• 제1권1호
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• pp.69-77
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• 1999

One of the objectives of any task design is to provide a safe and helpful workplace for the employees. The safety and health module may include means for confronting the design with safety and health regulations and standards as well as tools for obstacles and collisions detection (such as error models and simulators), Virtual Reality is a leading edge technology which has only very recently become available on platforms and at prices accessible to the majority of simulation engineers. The design of an automated manufacturing system is a complicated, multidisciplinary task that requires involvement of several specialists. In this paper, a design procedure that facilitates the safety and ergonomic considerations of an automated manufacturing system are described. The procedure consists of the following major steps. Data collection and analysis of the data, creation of a three-dimensional simulation model of the work environment, simulation for safety analysis and risk assessment, development of safety solutions, selection of the preferred solutions, implementation of the selected solutions, reporting, and training. When improving the safety of an existing system the three-dimensional simulation model helps the designer to perceive the work from operators point of view objectively and safely without the exposure to hazards of the actual system.

• 패션비즈니스
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• 제18권3호
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• pp.14-28
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• 2014

The purposes of this study are to provide comprehensive reviews on multichannel consumer behaviors published in peer-reviewed academic journals from 2005 to 2014, to develop a conceptual framework that demonstrates multichannel determinants such as psychographics, demographics, social influences, and situational factors on consumers' search and purchase behavior based on customers' profits or costs judgment, and to provide possible direction for future research in multichannel consumer behavior. Three steps were taken in the process of analyzing consumers' channel determinants presented in the 37 studies, and 12 most frequently used factors that appear in the studies were extracted. These factors include convenience, service, trust/risk, saving money, product knowledge, experience, efficacy/usefulness, involvement, shopping environment/situation factors, demographics, product types, and social influence. With 12 determinants of multichannel consumers' search and purchase behavior, a conceptual framework was proposed based on expectancy theory. The directions for future research were also discussed.

• International Journal of Computer Science & Network Security
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• 제21권5호
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• pp.133-138
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• 2021

The concept of inclusive development provides equal opportunities for all participants in access to the labor market and resource allocation. This concept emphasizes the equality of human capital, the ecological state of the environment, social protection and food security. This concept is fundamentally different from the standard perception of economic growth, because it has broader goals than simply increasing incomes and GDP. It rejects the position that positive results are an automatic consequence of growth; here the basic condition is human development and increase of its well-being, reduction of poverty. Therefore, it is not the result of distribution that becomes primary, but the involvement in the process of social reproduction. An alternative system of characterization of the country's position according to the resulting indicator of the Inclusive Development Index was presented at the World Economic Forum in Davos. In this research the methodical development of the system of estimation of the index of inclusive development for regions of the NUTS 4 level of the European classification is resulted.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.149.1-149
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• 2003

A lily strain of Cucumber mosaic virus (LK-CMV) was not able to systemically infect zucchini squash (Cucurbita pepo), while Fny strain of CMV (Fny-CMV) caused systemic mosaic and stunting symptom at 4 days post-inoculation on the same host species. The pathogenicity of LK-CMV in zucchini squash was investigated by reassortments of genomic RNAs of LK-CMV and Fny-CMV for infection, as well as by pseudorecombinants generated from biologically active transcripts of CDNA clones of LK-CMV and Fny-CMV, respectively. The assessments of pathogenicity for LK-CMV indicated that RNA2 of LK-CMV was responsible for systemic infection in zucchini squash. In the protoplast of zucchini squash, the RNA accumulations of all constructed pseudorecombinants were indistinguishable and LK-CMV replication was slightly lower than that of Fny-CMV, suggesting that the inability of LK-CMV to infect squash plants was responsible for the poor efficiency of virus movement, rather than the reduction of replication function.

• 국제학술발표논문집
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• The 3th International Conference on Construction Engineering and Project Management
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• pp.1307-1312
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• 2009

Design is an act based on multidisciplinary information. The involvement of various stakeholders makes it difficult to process, plan, and integrate. Iteration is frequent in most of the engineering design and development projects including construction. Design iterations cause rework, and extra efforts are required to get the optimal sequence and to manage the projects. The simple project management techniques are insufficient to fulfill the requirements of integrated design. This paper entails two things: design structure matrix and design parameters' information based model. The emphasis has been given to optimal sequence and crucial iteration using design structure matrix analysis technique. The design projects have been studied using survey data from industry. The optimal sequence and crucial iterations results have been utilized for proposed model. Model integrates two things: information about produced- required key design parameters and information of design changes during the design process. It will help to get familiar with Design management in order to fulfill contemporary needs.

• 국제학술발표논문집
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• The 6th International Conference on Construction Engineering and Project Management
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• pp.381-385
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• 2015

This research aims to investigate critical factors of the government's role in achieving success in Public Private Partnership (PPP) toll road projects in Indonesia according to government and private sectors' perceptions. A preliminary interview Subsequently a questionnaire survey was also conducted involving 143 respondents across the two sectors from eight operating toll were five critical factors of the government's roles in achieving success in PPP toll road projects, namely; "Active involvement in overall project stage activities", "Establishment of good bureaucracy", "Provision of conducive environment", "Appropriate project planning and competitive tendering" and "Provision of appropriate government support and supervision". This research finding is expected to assist the government in defining clear roles and underlying responsibilities in development of PPP toll roads in Indonesia.

• 토지주택연구
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• 제7권4호
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• pp.217-223
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• 2016

PSM기법은 자료수집의 편의성과 해석의 직관성 때문에 흔히 이용되는 가격결정기법이다. 그러나 PSM은 가격판단의 상황이 응답자에게 고관여상황으로 인식될 경우 의도적으로 가격을 낮추어 부르는 전략적 편의가 발생할 여지가 있다. 본 연구는 아파트 가격판단의 상황에서 잠재적수요자가 이를 고관여상황으로 인식할 경우 손실회피를 위해 가격을 낮추어 왜곡시키는 현상을 실증하고자 하였다. 2015년 분양된 LH 아파트 세 곳을 대상으로 한 실증연구 결과 모든 사업지구에서 잠재수요자의 수용가격대가 부동산업소의 수용가격에 비해 낮은 수준에서 형성되었음을 확인하였다. 또한 적정가격대 역시 부동산업소에 비해 최소한 유사하거나 낮은 수준에서 형성되었음이 나타났다. 이러한 현상은 잠재수요자가 부동산업소에 비해 가격판단의 상황을 고관여상황으로 인식하고 가격을 낮추어 손실을 기피하고자 하는 전망이론의 손실기피 현상이 작용한 것으로 판단된다. 실제분양가격과 초기계약률을 비교하였을 경우 손실기피로 인한 가격의 왜곡이 심한 잠재수요자보다 부동산업소의 PSM결과가 현실적인 효용성이 있음이 확인되었다. 다만 향후 연구에서는 관여도의 문제를 최소화할 수 있는 측정도구의 개발과 수용가격대와 적정가격대의 해석에 대한 새로운 접근이 모색되어야 할 것이다.