• 대한한방내과학회지
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• 제37권2호
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• pp.212-217
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• 2016

Objective: This study reports on two patient cases with lower limb symptoms related to femoral nerve entrapment who were treated with traditional Korean medicinal treatments.Method: We used acupuncture and pharmacopuncture for several days and observed any changes in the patients’ symptoms.Results: After treatment, the numerical rating scale (NRS) of the first patient decreased from 7 to 1, while that of the second patient decreased from 10 to 1.Conclusion: The results of this study suggest that traditional Korean medicinal treatments may be effective in reducing symptoms related to femoral nerve entrapment.

• Geomechanics and Engineering
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• 제17권3호
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• pp.237-245
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• 2019

In deep mixed rock strata, a double shield TBM (DS-TBM) is easy to be entrapped by a large force during tunneling. In order to reduce the probability of the entrapment, we need to investigate a favorable driving direction, either driving with or against dip, which mainly associates with the angle between the tunneling axis and strike, ${\theta}$, as well as the dip angle of rock strata, ${\alpha}$. We, therefore, establish a 3DEC model to show the changes of displacements and contact forces in mixed rock strata through LDP (longitudinal displacement profile) and LFP (longitudinal contact force profile) curves at four characteristic points on the surrounding rock. This is followed by a series of numerical models to investigate the favorable driving direction. The computational results indicate driving with dip is the favorable tunneling direction to reduce the probability of DS-TBM entrapment, irrespective of ${\theta}$ and ${\alpha}$, which is not in full agreement with the guidelines proposed in RMR. From the favorable driving direction (i.e., driving with dip), the smallest contact force is found when ${\theta}$ is equal to $90^{\circ}$. The present study is therefore beneficial for route selection and construction design in TBM tunneling.

• Clinical Pain
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• 제20권2호
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• pp.122-126
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• 2021

When a patient represents pain in foot, physician can easily overlook compression neuropathy of peripheral nerve as it is uncommon. Among nerve entrapment syndrome encountered in the foot, selective compression in lateral branch of deep peroneal nerve (DPN) is rare. We report a case of a patient with pain and dysesthesia in dorsolateral foot which turned out as lateral branch of deep peroneal nerve entrapment syndrome caused by talonavicular joint effusion. We would like to share diagnostic work up flow and conservative treatment courses. This case manifests the importance of the deep peroneal nerve and its branches in clinical setting of pain and ankle instability.

• 대한수의학회지
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• 제63권2호
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• pp.11.1-11.5
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• 2023

A seven-month pregnant four-year-old Thoroughbred mare with colic weighing 600 kg was referred to the Jeju National University Equine Hospital. A physical examination and ultrasound suggested epiploic foramen entrapment. The patient underwent ileum resection and end-to-side jejunocecostomy. After surgery, the horse showed a consistent pain when introduced to feeding. A repeat laparotomy was performed to enlarge the stoma size with side-to-side jejunocecostomy. The repeat laparotomy was successful, and the mare gave birth uneventfully. This report describes a case of small intestinal epiploic foramen entrapment and the clinical outcomes of the 2 consecutive laparotomies a Thoroughbred mare in late gestation.

• 공업화학
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• 제17권2호
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• pp.138-143
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• 2006

Ethosome은 에탄올에 용해된 레시틴을 친수성 용액으로 수화시켜 만들어지는 액정형 베시클이다. Ethosome을 약물전달체로 개발하기 위해서는 베시클의 높은 포집효율과 작은 입자크기가 필수적이기 때문에 ethosome의 포집효율과 입자크기에 영향을 주는 인자들에 대한 연구를 시도하였다. Calcein을 친수성 지표물질로 사용하여 ethosome을 만들고, 구성 성분비와 제조조건에 따른 ethosome의 특성의 변화를 관찰하였다. 에탄올과 calcein 용액의 첨가량 레시틴 중 포스파티딜콜린의 함량, 제조온도, 교반속도 및 PBS 첨가방법 등이 ethosome의 특성에 상당히 큰 영향을 미치는 것을 확인하였다. 초음파 처리를 한 경우에는 ethosome의 포집효율이 감소하는 결과가 나타났는데 이러한 결과는 강한 초음파 진동에 의해 베시클에 포집되었던 성분이 방출되었기 때문이다.

• 대한정형외과스포츠의학회지
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• 제9권2호
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• pp.121-124
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• 2010

발바닥 부위에 반복적인 저 에너지의 자극이 가해지는 선수들에게는 건염, 피로 골절, 또는 과사용 증후군과 같은 병변이 자주 관찰된다. 운동 선수들에게 발생하는 발뒤꿈치 통증의 대부분의 원인은 족저 근막염이고, 이 는 족저 근막의 반복적 자극에 의해 발생한다. 대부분 보존적인 치료 방법으로 증상의 호전을 보이고 운동에 복귀한다. 흔하지는 않지만, 발뒤꿈치 통증의 원인이 되는 신경 압박병증도 반복적인 자극에 따른 신경의 주변조직 비후에 의해 발생할 수도 있다고 한다. 저자들은 발 부위에 저 에너지의 반복적인 자극이 가해지는 농구 선수에게서 만성 족저 근막염이 동반된 외측 족저 신경의 압박병증을 관찰하였고, 발생 가능한 기전과 증례를 문헌 고찰과 함께 보고하고자 한다.

• 약학회지
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• 제40권5호
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• pp.522-531
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• 1996

5-fluorouracil(5-FU) derivatives synthesized with four N-acyloxycarbonyl group such as 1-(N-t-butyloxycarbonyl)glycyloxymethyl-5-FU(BGFU), 1-(N-t-butyloxycarbonyl)leucyloxymethy l-5-FU(BLFU), 1-(N-t-carbobenzyloxymethyl)glycyoxymethyl-5-FU(CGFU) and 1-(N-t-carbobenzyloxymethyl)leucyloxymethyl-5-FU(CLFU) were entrapped into liposomes with different lipid compositions. The entrapment efficiency and release rate of drugs from each liposomes were evaluated. The particle size of liposomes, cytotoxicity and stability of drug-entrapped in liposomes were evaluated. The entrapment efficiency in 5-FU derivatives liposomes was dependent on the lipophilicity of N-acyloxymethyl derivatives. The drug entrapment efficiency also increased on the content of lipid increased up to 200mcmol of lipid per milliliter of liposomal solution. However, inclusion of additives such as cholesterol, dicetylphosphate and stearylamine decreased the entrapment efficiency. The mean particle size and size distribution were varied with lipid compositions and lipophilicity of prodrugs. The release rates of drugs from liposomes were not affected by additives, but those of BGFU and CGFU entrapped in liposomes with cholesterol decreased. Cytotoxicity of BLFU and CLFU entrapped in liposomes decreased by 3~5 fold compared with those of free two prodrugs. Liposome-entrapped 5-FU prodrugs were more stable either at pH 7.4 or in human plasma. Especially, 5-FU prodrugs entrapped in liposome with dipalmitoylphosphatidylcholine(DMPC) was the most stable in human plasma. Compared with free BLFU, BLFU entrapped in DMPC liposome showed a superior antitumor activity at all doses used. In contrast, CLFU entapped in liposomes were more toxic than free prodrug.

• Archives of Plastic Surgery
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• 제37권6호
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• pp.815-818
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• 2010

Purpose: Soft tissue chondroma is a rare benign tumor, found mainly on the palm and sole and grows slowly. Typically, mature hyaline cartilage is the dominant pathological feature. There are reports that assert soft tissue chondromas to be a cause of median nerve entrapment syndrome. However, this is the first case report showing soft tissue chondroma to be a cause of simultaneous median and ulnar neuropathy. Methods: A 62 year-old woman presented with chief complaints of numbness and hypoesthesia of her right palm for 4 to 5 years, and a palpable mass on her right palm that had been increasing in size slowly for 3 years. Physical examination revealed a firm, mobile, non-tender and about $3{\times}3\;cm^2$ sized mass in the center of the right palm. Electromyography showed entrapment neuropathy of the median and ulnar nerve. Ultrasonography showed an approximately $5.7\;cm^2$ mass below the flexor tendon of ring finger. Upon surgical excision, a $3{\times}3\;cm^2$ mass attached to the flexor digitorum profundus of ring finger and redness and hypertrophy of both the median and ulnar nerve were discovered. Mass excision was performed gently and the specimen was referred for histopathologic study. Mass excision resulted in median and ulnar nerve release. Results: The pathology report confirmed the mass to be a soft tissue chondroma with mature hyaline cartilage. The patient exhibited post-operative improvement of her symptoms and did not show any complications. Conclusion: This is the first case report showing soft tissue chondroma to be a cause of simultaneous median and ulnar neuropathy.

• 한국응용과학기술학회지
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• 제39권6호
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• pp.792-801
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• 2022

본 연구는 간호대학생의 평가염려 완벽주의, 속박감 및 우울 정도를 파악하고, 우울에 영향을 미치는 요인을 규명하고자 시행된 서술적 조사연구이다. 연구대상자는 G시 2개의 간호학과에 재학 중인 학생을 대상으로 하였다. 자료 분석을 위해 기술적 통계, t-test, ANOVA, Pearson 상관계수, 다중회귀분석으로 분석하였다. 연구결과, 간호대학생의 우울에 미치는 영향요인은 외적속박감(β=.414, p<.001), 사회부과적 완벽주의(β=.174, p<.001)였고, 대상자의 우울정도를 24.9%를 설명하였다. 특히 외적속박감이 22.7%로 가장 큰 영향을 미치는 것으로 나타났다. 이에 본 연구결과를 토대로 간호대학생의 우울감을 낮추고 조기 예방하기 위해 우울을 관리할 수 있는 외적속박감, 사회부과적 완벽주의을 감소시킬 수 있는 다양한 비교과 프로그램을 개발하여 지속적인 관심을 두고 관리할 필요가 있다.

• 대한족부족관절학회지
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• 제15권1호
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• pp.44-46
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• 2011

Sural nerve is a sensory nerve that innervates the lateral side of ankle and foot, and the injury of this nerve can be usually caused by surgical approch of calaneal fracture or achilles tendon injury. Entrapment neuropahty of sural nerve caused by bony fragment after calcaneal fracture is not reported, yet. Authors experienced one case that sural nerve injury due to bony fragment after calcaneal fracture and we regard that it is a rare case, so we report this case after reviewing literatures.