• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5469-5475
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• 2012

Background and Objectives: Acute lymphoblastic leukemia (ALL) is a complex genetic disease involving many fusion oncogenes (FO) having prognostic significance. The frequency of various FO can vary in different ethnic groups, with important implications for prognosis, drug selection and treatment outcome. Method: We studied fusion oncogenes in 101 pediatric ALL patients using interphase FISH and RT-PCR, and their associations with clinical features and treatment outcome. Results: Five most common fusion genes i.e. BCR-ABL t (22; 9), TCF3-PBX1 (t 1; 19), ETV6-RUNX1 (t 12; 21), MLL-AF4 (t 4; 11) and SIL-TAL1 (del 1p32) were found in 89/101 (88.1%) patients. Frequency of BCR-ABL was 44.5% (45/101). BCR-ABL positive patients had a significantly lower survival ($43.7{\pm}4.24$ weeks) and higher white cell count as compared to others, except patients with MLL-AF4. The highest relapse-free survival was documented with ETV6-RUNX1 (14.2 months) followed closely by those cases in which no gene was detected (13.100). RFS with BCR-ABL, MLL-AF4, TCF3-PBX1 and SIL-TAL1 was less than 10 months (8.0, 3.6, 5.5 and 8.1 months, respectively). Conclusions: This is the first study from Pakistan correlating molecular markers with disease biology and treatment outcome in pediatric ALL. It revealed the highest reported frequency of BCR-ABL FO in pediatric ALL, associated with poor overall survival. Our data indicate an immediate need for incorporation of tyrosine kinase inhibitors in the treatment of BCR-ABL+ pediatric ALL in this population and the development of facilities for stem cell transplantation.

• The Korean Journal of Physiology and Pharmacology
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• 제23권1호
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• pp.89-89
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• 2019

• 한국자동차공학회논문집
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• 제14권3호
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• pp.22-27
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• 2006

As the regulation and assessment program for safety of passengers become stringent, automakers are required to develop lighter and safer vehicles. In order to fulfill both requirements which conflict with each other, automobile and steel companies have proposed the application of AHSS(Advance High Strength Steel) such as DP, TRIP and martensite steel. ULSAB-AVC model is one of the most remarkable reactions to offer solutions with the use of steel for the challenge to improve simultaneously the fuel efficiency, passenger safety, vehicle performance and affordability. This paper is concerned with the crash analysis of ULSAB-AVC model according to the US-SINCAP in order to compare the effectiveness between the model with AHSS and that with conventional steels. The crashworthiness is investigated by comparing the deformed shape of the cabin room, the energy absorption characteristics and the intrusion velocity of a car.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2004년도 하계종합학술대회 논문집(1)
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• pp.55-58
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• 2004

This this paper, we propose vertical Bell laboratories layered space time (V-BLAST) system based on variable rate Low-Density Parity Check (LDPC) codes to improve performance of receiver when QR decomposition interference suppression combined with interference cancellation is used over independent Rayleigh fading channel. The different rate LDPC codes can be made by puncturing some rows of a given parity check matrix. This allows to implement a single encoder and decoder for different rate LDPC codes. The performance can be improved by assigning stronger LDPC codes in lower layer than upper layer because the poor SNR of first detected data streams makes error propagation. Keeping the same overall code rates, the V-BLAST system with different rate LDPC codes has the better performance (in terms of Bit Error Rate) than with constant rate LDPC code in fast fading channel.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2005년도 추계종합학술대회
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• pp.301-306
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• 2005

In this paper, we propose P-SRA (Proposed Simplified Resource Allocation) algorithm for efficient resource allocation for real time traffic in MIMO-OFDMA (Multiple Input Multiple Output - Orthogonal Frequency Division Multiple Access) systems with V-BLAST (Vertical-Bell laboratories LAyered Space-Time coding) detector. The proposed P-SRA scheme employs efficient 3 step resource allocation algorithm with plain V-BLAST and no H-ARQ, however it achieves comparable performance of a MIMO-OFDMA system utilizing error compensated V-BLAST and H-ARQ IR scheme.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송공학회 2009년도 IWAIT
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• pp.628-631
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• 2009

In this paper, we proposed a new authentication method using video that was taken during moving a hand-held camera in front of the face. The proposed method extracted individuality from the obtained image sequences using the parametric eigenspace scheme. Changes of facial appearance through authentication trials draw continuous tracks in the low dimensional igenspace. The similarity between their continuous tracks are calculated by DP-matching to verify their identities. Experimental results confirmed that different motions and persons change the shapes of continuous tracks, so the proposed method could identify the person.

• 설비공학논문집
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• 제23권2호
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• pp.103-110
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• 2011

A two-dimensional immiscible droplet deformation phenomena on moving wall in a channel has been investigated by using lattice Boltzmann method involving two-phase model. The dependence of the deformation of the droplet with different sizes on the contact angle and the velocity of bottom wall has studied. When the bottom wall starts to move, the deformation of the droplet occurs. For the largest bottom wall velocity, eventually, the deformation of the droplet is classified into the three patterns according to the contact angle.

• 대한안전경영과학회지
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• 제9권3호
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• pp.41-47
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• 2007

The purpose of this study is to collect and analyze their opinions to found solutions for reducing safety accidents since it is important to educate the students to recognize the importance of safety. We surveyed 350 students from mechanical and metal engineering departments of an engineering high school located in Seoul, and divided them in two categories and asked them about prevention of safety accidents in laboratories. It is found that further directions and educations are needed for the students as to emergency measures in case of safety accidents. Safety education before laboratory classes is crucial, helpful and effective for prevention of safety accidents. Facility factors that further education is needed for students who don't experiments in orderly manner.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2008년도 춘계학술발표대회 개요집
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• pp.48-48
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• 2008

• Journal of Photoscience
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• 제5권2호
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• pp.63-67
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• 1998

New photoinitiator systems of dimethylphenacylsulfonium butyltnphenylborate (DMPSB) as a donor-acceptor initiator and styryl dyes have been investigated for free radical polymerization of an acrylate with visible lasers (488, 514 and 647 nm). DMPSB was able to be sensitized by many styryl dyes. When polymerized with pentaerythrithol triacrylate, the sensitivity value of the photosensitive layer containing DMPSB was higher than that of an tetrabutylammonium butyltnphenylborate (TBAB) as an electron donating initiator or a dimethylphenacylsulfonium tetrafiuoroborate (DMPS) as an electron accepting initiator. The sensitivity values of the photosensitive layer containing the photoinitiator systems had a close relation to the free energy changes between the excited singlet styryl dyes and DMPSB.