• Title/Summary/Keyword: elucidation

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5 Cases of Bone Scan with Sr-85 (Sr-85를 이용(利用)한 골(骨) 스캔 5례(例))

  • Yoo, H.S.;Park, C.Y.;Choi, B.S.
    • The Korean Journal of Nuclear Medicine
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    • v.7 no.2
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    • pp.37-41
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    • 1973
  • Bone scanning was attempted in the five representative cases in various diseases such as primary bone tumor, inflammatory or traumatic changes, secondary metastatic bone tumor and changes in the hematopoietic system with Sr-85 which is available at this time. Each findings were correlated to the X-ray findings. Scan findings were more appreciable than the X-ray findings in elucidation of extent of bone pathology in cases of primary bone tumor and fracture cases. Especially, increased radioactivity was noted on the clinically suspected region which were not demonstrated on the plain X-rays.

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Analysis of Compression-induced Auto-ignition Combustion Characteristics of HCCI and ATAC Using the Same Engine

  • Iijima, Akira;Shoji, Hideo
    • Journal of Mechanical Science and Technology
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    • v.20 no.9
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    • pp.1449-1458
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    • 2006
  • Controlled Auto-ignition (CAI) combustion processes can be broadly divided between a CAI process that is applied to four-cycle engines and a CAI process that is applied to two-cycle engines. The former process is generally referred to as Homogeneous Charge Compression Ignition (HCCI) combustion and the later process as Active Thermo-Atmosphere Combustion (ATAC) The region of stable engine operation differs greatly between these two processes, and it is thought that the elucidation of their differences and similarities could provide useful information for expanding the operation region of HCCI combustion. In this research, the same two-cycle engine was operated under both the ATAC and HCCI combustion processes to compare their respective combustion characteristics. The results indicated that the ignition timing was less likely to change in the ATAC process in relation to changes in the fuel octane number than it was in the HCCI combustion process.

Design, Synthesis, and Antimicrobial Activity, of New 1,4-disubstituted Octahydroquinoxaline-2,3-dione Derivatives

  • Hussein, Mostafa A.
    • Bulletin of the Korean Chemical Society
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    • v.32 no.5
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    • pp.1511-1518
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    • 2011
  • A series of 1,4-disubstituted octahydroquinoxaline-2,3-dione derivatives was prepared through two steps reaction. The latter involves the formation of N,N-disubstituted cyclohexane-1,2-diamine derivatives (la-j) through reductive alkylation of 1,2-cyclohexanediamine with different aldehydes in presence of sodium cyanoborohydride. Fusion of compounds (1a-j) with diethyl oxalate affording the target compounds (2a-j). Elucidation of structures of compounds (2a-j) was based upon different spectral data as well as the elemental methods of analyses. In addition, mass spectrometry and X-ray diffraction analyses were carried out. Moreover, the lipophilicity of the target compounds as expressed from the Clog P. Most of the test compounds (2a-j) showed weak to moderate antibacterial and antifungal activities against most of the used bacterial and fungal strains in comparison to chloramphenicol and clotrimazole as reference drugs respectively.

Endpoint of Cancer Treatment: Targeted Therapies

  • Topcul, Mehmet;Cetin, Idil
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4395-4403
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    • 2014
  • Nowadays there are several limitations in cancer treatment. One of these is the use of conventional medicines which not only target cancer cells and thus also cause high toxicity precluding effective treatment. Recent elucidation of mechanisms that cause cancer has led to discovery of novel key molecules and pathways which have have become successful targets for the treatments that eliminate only cancer cells. These so-called targeted therapies offer new hope for millions of cancer patients, as briefly reveiwed here focusing on different types of agents, like PARP, CDK, tyrosine kinase, farnysyl transferase and proteasome inhibitors, monoclonal antibodies and antiangiogenic agents.

Intensive Anatomical Studies on the Du Channel and the Ren Channel (독맥경과 임맥경에 대한 심층해부학)

  • Kim, Su-Myung
    • Journal of Haehwa Medicine
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    • v.12 no.2
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    • pp.199-225
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    • 2004
  • For the purpose of experimental and clinical studies on the 14 channels and collaterals, we performed an inquiry on the anatomical mapping of neronal, circulatory and muscular networks in the human body which possibly correspond to the major pathway of Du channel and Ren channel known to be critical for overall controlling and mediating 12 regular channel connections. The theoretical background of this analysis was based on the oriental medicinal treatises which described acu-points and related anatomical informations. We suggest that rearrangement methodology for the 12 regular channels as described here may be applied to other 12 regular channels and to develop the new concept on the elucidation of the medical efficacy based on precise anatomical localization of channels and collaterals as well as the meridian points. It is proposed that interdisciplinary studies between oriental and western medicine are critical for more efficient achievement.

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A Study on the Making and Trends of Interactive Movies (인터랙티브 무비의 관한 연구 - 제작과 동향을 중심으로 -)

  • Park, Yoon-Sung
    • Journal of Digital Contents Society
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    • v.8 no.2
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    • pp.227-233
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    • 2007
  • Movie Films and Games, to be close to their industries, needs in crossover fields, are affected to each other. Interactive movie is an effective authoring method accommodating this trend on demands. However, studies which explore and examine various forms of Interactive effected films and storytelling approaches are scarce. This call for elucidation is basis of this research which applies the notion of Interactive movies and games to analyzing of trends and composition limits of Interactive movies, and improvised methodology of ability on merits for the next generation media cultures.

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Hydrogen Bonding in Aromatic Alcohol-Water Clusters: A Brief Review

  • Ahn, Doo-Sik;Jeon, In-Sun;Jang, Sang-Hee;Park, Sung-Woo;Lee, Sung-Yul;Cheong, Won-Jo
    • Bulletin of the Korean Chemical Society
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    • v.24 no.6
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    • pp.695-702
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    • 2003
  • Recent experimental and theoretical advances on the aromatic alcohol-water clusters are reviewed, focusing on the structure of the hydrogen bonding between the alcoholic OH group and the binding water molecules. The interplay of experimental observations and theoretical calculations for the elucidation of the structure is demonstrated for phenol-water, benzyl alcohol-water, substituted phenol-water, naphthol-water and tropolone -water clusters. Discussion is made on assigning the role (either proton-donating or -accepting) of the hydroxyl group by measuring the shifts of infrared frequency of the OH stretching mode in the cluster from that of bare aromatic alcohol for the experimental determination of the cluster structure.

Structure Elucidation of Sesquiterpenoid from Pathogenic Fungus Bipolaris cynodontis (식물 병원균 Bipolaris cynodontis로부터 분리한 세스퀴테르펜류 화합물의 구조 분석)

  • Lim, Chi-Hwan
    • Analytical Science and Technology
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    • v.9 no.1
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    • pp.107-111
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    • 1996
  • A phytotoxic compound was isolated from a culture of Bipolaris cynodontis, a fungus pathogenic to Bermuda grass. The structure was determined by spectroscopic analyses including 2D NMR experiments, to be sesquiterpene having a 9-carbon unit side chain. The compound inhibits the root growth of the seedlings of Italian ryegrass and rice plant, the host plant of the B. cynodontis, by about 100% at 100ppm, and it is suggested that this may play an important role in the expression of the disease symptom.

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Elucidation of Pyeongwi-san from the Pathological Point of View (병리학적 관점에서 본 평위산(平胃散)의 소고)

  • Lee, Kwang-Gyu
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.5
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    • pp.773-776
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    • 2011
  • This study was focused on a certain clinical symptom, which could applicated by Pyeongwi-san, and the radical treatment. Pyeongwi-san is applicable to dampness retention in the spleen and stomach, accompanied by abdominal fullness, anorexia, nausea and regurgitation. Main action of Pyeongwi-san is to dry dampness, invigorate the spleen, promote the flow of gi, and regulate the stomach. The herbal remedy drying dampness like Pyeongwi-san however, is just indicatio symptomatica therefore radical treatment must be used together. Jeunginmaegchi, a medical book written by Gyeong-Myeong Jin, who was lived in Myeong dynasty. This book contains many clinical applicable symptoms and constituents derived from Pyeongwi-san. The herbal prescriptions composing Pyeongwi-san is composed of Changchul, Hubak, Jinpi, Gamcho. The major action of these herbs is drying dampness. Therefore, it shoud be seriously consider that curative therapy must eliminate the cause of endogenous dampness.

Elucidation of Bojungikgi-tang from the Pathological Point of View (병리학적(病理學的) 관점에서 바라본 보중익기탕(補中益氣湯))

  • Lee, Kwang-Gyu
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.5
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    • pp.784-789
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    • 2010
  • Syndrome of asthenia of spleen gi usually caused by improper diet, overstrain, emotional upsets, followed by syndrome of sinking of splenic gi. There are several pathologic categories of splenic gi deficiency syndrome. These include failure to nourish the body, failure to astringe liquid substances, failure of splenic gi to rise, gi stagnation in which gi can't disperse normally, failure of transportation. In the splenic gi deficient situation, body fluid is usually stagnated because the rest of the water absorbed from the food is transported to every part of the body by the action of splenic gi. In addition, there is abnormal sinking of clear gi, followed by fever due to gi deficiency. Bojungikgi-tang is composed of restoratives which are invigorating splenic gi and herbs which uplift splenic gi. It is mainly applicable to splenic gi deficiency syndrome accompanied by gi stagnation and fluid accumulation.