• The Korea Journal of Herbology
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• v.25 no.3
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• pp.149-157
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• 2010

Objective：Gagam-Gongjin-dan (GGD) is an oriental medicinal prescription composited with Cervi parvum Cornu, Corni Fructus, Angelica Gigantis Radix, Lycii Fructus, Dioscoreae Rhizoma, Citri Pericarpium, Gastrodiae Rihzoma, Agastachis Herba, Cassiae cortex, Scutellariae Radix and Schisandrae Fructus. The purpose of this study was to investigate the effects of GGD extract against acetaminophen (APAP)-induced liver injury in mice. Methods：GGD extract was prepared by extracting with methanol for 7 days. The extract was freeze-dried following filtration through vacuum distillation system. The first, we investigated the antioxidant effects of GGD extract on electronic donating ability (DPPH), nitrite (NO) scavenging and superoxide dismutase (SOD)-like activity. The next, we investigated the possible hepatoprotective effect of GGD extract administration against acetaminophen-induced liver injury in mice. Mice were orally administrated with or without GGD extract of different doses (25-100 mg/kg/day) one times per day for 6 days. After 3 days, APAP was orally applied with a single dose (400 mg/kg). Results：GGD extract increased DPPH, NO and SOD-like activities in dose dependant. APAP treatment significantly increased aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities in plasma. Also, APAP treatment significantly evaluated lipid peroxidation product thiobarbituric reacting substances (TBARS) and depleted some antioxidant enzymes (superoxide dismutase, catalase, d-aminolevulinate dehydratase and gluthathione peroxidase activities) in liver homogenates compared to the control group. However, the orally administration of GGD extract was able to counteract these effects. Histological studies provided supportive evidence for biochemical analysis Conclusions：These results suggest that GGD extract has a potential antioxidant and hepatoprotective effect against APAP-induced liver injury, these properties may contribute to liver disease care.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.10 no.4
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• pp.350-357
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• 2017

This study was conducted as a post - study on the development of a centralized controller and a hydraulic lift system including structural analysis and remote control for the development of a vertically elevated car. The safety review was carried out through the structural modification of the elevator lift which was developed during the previous research. 3D modeling was performed with Solidworks, and a model of finite element was created through Hypermesh S / W. In addition, the loading environment of the work vehicle for the evaluation is a condition in which the loading amount is 250 kg per position (total, upper, upper, lower, and lower) on the work table, ), The structural analysis was carried out under the condition that the load was 600 kg, and safety was examined in various aspects. As a result, when the allowable load of 250 kg and the excess load of 600 kg are excluded (except Case-11), the stress level is below the yield strength. In the case of Case-11, there is a region exceeding the yield strength at the center support portion of the safety bar at the upper end even after excluding the component which generates the maximum stress, but it does not affect the safety aspect of the whole structure Respectively. Looking at the deflection results, it can be seen that in all cases the maximum deflection occurs in the same table, and the tendency of sagging in both 250 kg and 600 kg is the same.

• Journal of Technology Innovation
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• v.23 no.3
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• pp.287-316
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• 2015

The trend of R&D in automotive electronics industry is shifting towards ECU(Electronic Control Units) based on softwares which requires technology convergence to accommodate customers' requests on safety and convenience. The trend requires systemized R&D paradigm which reflects increased role of softwares. As the softwares became the core components in automotive innovation, there has been wide range of efforts to introduce software R&D processes and methodologies such as CMMI, A-SPICE and ISO-26262 etc. However, R&D departments in the industry fields are confronted with conflicts which arise from discrepancies among the individual process. In this study, we focus on suggesting our integrated and systematic R&D process with the aim of alleviating the conflicts and confusions. For this purpose, we analyze the cases of Korean automotive electronics companies to compare various R&D processes in the field and their relationships. Based on the analysis, we derive and suggest our model of R&D process which effectively integrate ISO/TS-16949 for manufacturing quality and CMMI, A-SPICE, ISO-26262 for system with softwares.

• The Journal of the Korea Contents Association
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• v.10 no.6
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• pp.480-488
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• 2010

The aim of this study were to examine the effects of virtual reality program on balance and activities of daily living in children with spastic cerebral palsy (CP) using the Pediatric Balance Scale (PBS) and the Functional Independence Measure for Children (WeeFIM), and to measure relationship between the PBS and the WeeFIM. For this, A total of 20 spastic CP classified as the Gross Motor Function Classification System (GMFCS) I and II were employed. The Participant's were allocated randomly to 2 groups: a virtual reality group (n=10) and the control group (n=10). Both groups received muscle strengthening exercise for 3 sessions, 30 minutes per week over a 12 week period. The virtual reality group practiced additional virtual reality program. The virtual reality group showed significant increases in balance (p<0.05) and activities of daily living (p<0.05). There were a significant correlation between the PBS and the WeeFIM (p<0.05). Application of the virtual reality program to treat the spastic CP will be feasible and suitable. And the PBS was a useful tool to predict activities of daily living in the spastic CP.

• The Journal of Society for e-Business Studies
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• v.9 no.3
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• pp.155-167
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• 2004

At this time, the two main techniques for achieving web personalization assistant systems generally concern direct manipulation and software agents. While both direct manipulation and software agents are intended for permitting user to complete tasks rapidly, efficiently, and easily, their methodologies are different. The central debate involving these web personalization techniques originates from the amount of control that each allows to, or holds back from, the users. Direct manipulation can provide users with comprehensibel, predictable and controllable user interfaces that give them a feeling of accomplishnent and responsibility. On the other hand, the intelligent software components, the agents, can assist users with artificial intelligence by monitoring or retrieving personal histories or behaviors. In this empirical study, two web personalization assistant systems are evaluated. One of them, WebPersonalizer, is an agent based user personalization tool; the other, AntWorld, is a collaborative recommendation tool which provides direct manipulation interfaces. Through this empirical study, we have focused on two different paradigms as web personalization assistant systems : direct manipulation and software agents. Each approach has its own advantages and disadvantages. We also provide the experimental result that is worth referring for developers of electronic commerce system and suggest the methodologies for conveniently retrieving necessary information based on their personal needs.

• Korean Journal of Clinical Pharmacy
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• v.22 no.4
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• pp.330-339
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• 2012

Background : Hypertension is treated with both lifestyle modification and pharmacotherapy. The Seventh Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC-7), published in 2003, provides a streamlined management approach to hypertension for the primary care physician. The JNC-7 is the gold standard also in Korea. According to the JNC-7, special therapeutic considerations are recommended for high-risk individuals with compelling indications. The presence of compelling indications in any given patient should be considered when selecting specific pharmacotherapy to treat hypertension. However, in patients with compelling indications, it is unknown that hepatotoxicity is caused by Calcium Channel Blocker (CCB), one of 1st anti-hypertensive drugs. Now, the CCB is the most used 1st anti-hypertensive drug in Korea Therefore, we evaluated the changes in blood liver function parameters (ALT, AST, Total bilirubin, serum albumin) for the study group. Methods : We randomly collected and retrospectively analyzed Electronic Medical Record data (n=28,788) of patients, and who took calcium channel blockers(non-dihydropyridines; diltiazem, verapamil, dihydropyridines; amlodipine, barnidipine, benidipine, clinidipine, efonidipine, felodipine, isradipine, lacidipine, lercanidipine, nicardipine, nifedipine, nimodipine), with having liver function tests (LFTs) from July 1st 2009 to June 30th 2010 at the Seoul National University Hospital in Korea. Control groups are two antihypertensive agents: RAS blockade (ARB; candesartan, irbesartan, losartan, olmesartan, telmisartan, valsartan, ACE-I; cilazapril, enalapril, fosinopril, imidapril, perindopril, ramipril) and, Diuretics (loop; furosemide, torsemide, thiazide; hydrochlorothiazide[HCTZ], indapamide). Patients not having LFT results at these three standard points of time(baseline, during, medication, and after finishing medication) were excluded. The collected data were analyzed by using the SPSS (Version12.0) and Microsoft Excel (Version2007). Results : 711 patients who were treated CCB (297), RAS blockade (232) or Diuretics (182) monotherapy were selected for the study. In selected patients, liver damage degree(changes of each LFTs value) was higher in diuretics group than other groups, followed by RAS blockade and CCB. In diuretics group's was loop-diuretics group was higher than thiazide-diuretics group. In CCB group, Nondihydropyridine-CCB's damage degree was higher than Dihydropyrine-CCB's that. Conclusions : Despite the limitations due to the retrospective study, among patients with abnormal LFTs, the use of CCBs led to a less liver damage than other 1st anti-hypertensive agents. It can be recommended CCBs as one of the initial treatments of hypertension in patients with liver disease.

• Journal of IKEEE
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• v.19 no.3
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• pp.319-326
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• 2015

This paper proposes method about development of conversion software for controller without OPC stack to communicate with OPC DA client. The proposed method is composed of development of OPC server based on OPC DA standard protocol, development of GUI application can be checked the OPC tag and point informations, development of conversion module to convert from OPC protocol to open standard protocol. In the stage of development of OPC server based on OPC DA standard protocol, we develope server in the pc to transmit and receive datum through OPC DA protocol with OPC DA client. In the stage of evelopment of GUI application can be checked the OPC tag and point informations, run the OPC DA server and register to window system registry and check OPC tags, points, transmitting and receiving of data from serial communication. In the stage of development of conversion module to convert from OPC protocol to open standard protocol, convert from OPC tag data which has received from OPC DA client to protocol can be communicated with industrial controller using open standard protocol so that support to transmit and receive data. To evaluate the efficiency of the proposed software, we connected OPC DA server software and OPC client, and 5 sample industrial controller which use open standard protocol, as a result we got 96.98% average communication succeeding rate among entire transmitting and receiving packets. We also confirmed that successfully communicated between industrial building controller which uses modbus protocol and industrial OPC DA client using OPC DA conversion software proposed by this dissertation.

• 전자공학회논문지 IE
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• v.49 no.1
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• pp.18-23
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• 2012

In this paper, a potable device application for DC-DC converter was designed for voltage protection circuit. Voltage protection circuit to offer the under voltage lock out and over voltage protection consists of a comparator and bais circuits were implemented using. XFAB 1um CMOS process, SPICE simulations was confirmed through the characteristics. Simulation results, under voltage lock out input voltage is 4.8 V higher when the turn-on and, 4.2 V less when turn-off. When the input voltage is low voltage is applied can be used to prevent malfunction of the circuit. Over voltage protection is 3.8 V reference voltage when the output voltage caused by blocking circuit prevents device destruction can be used to improve the stability and reliability. The virtual control circuits of the DC-DC converter connected. According to the results of the abnormal voltage, voltage protection circuit behavior was confirmed. The proposed voltage protection circuit of the DC-DC converter cell is useful are considered.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.4
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• pp.331-339
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• 2018

The IEEE 1588, commonly known as a precision time protocol (PTP), is a standard for precise clock synchronization that maintains networked measurements and control systems. The best master clock (BMC) algorithm is currently used to establish the master-slave hierarchy for PTP. The BMC allows a slave clock to automatically take over the duties of the master when the slave is disconnected due to a link failure and loses its synchronization; the slave clock depends on a timer to compensate for the failure of the master. However, the BMC algorithm does not provide a fast recovery mechanism in the case of a master failure. In this paper, we propose a technique that combines the IEEE 1588 with network bonding to provide a faster recovery mechanism in the case of a master failure. This technique is implemented by utilizing a pre-existing library PTP daemon (Ptpd) in Linux system, with a specific profile of the IEEE 1588 and it's controlled through bonding modes. Network bonding is a process of combining or joining two or more network interfaces together into a single interface. Network bonding offers performance improvements and redundancy. If one link fails, the other link will work immediately. It can be used in situations where fault tolerance, redundancy, or load balancing networks are needed. The results show combining IEEE 1588 with network bonding enables an incredible shorter recovery time than simply just relying on the IEEE 1588 recovery method alone.

• Journal of Hospice and Palliative Care
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• v.21 no.3
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• pp.84-91
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• 2018

Purpose: This study aims to investigate treatment of cancer patients at a secondary hospital. Methods: A retrospective analysis was performed with electronic medical records of cancer patients admitted to a secondary hospital from January 1, 2009 through September 31, 2017. Results: A total of 223 patients were studied. Sixty-nine patients were hospitalized for supportive care after receiving a surgery, chemotherapy, and radiotherapy at a tertiary hospital, 58 patients for other supportive care, 53 patients for symptom control, 16 patients with a decision not to take active cancer treatment, and 27 patients for treatment of cancer that was diagnosed during their hospital stay. Among 75 patients who were discharged to other institutions, 50 were transferred to tertiary hospitals, 10 to long-term care hospitals, eight to hospice hospitals, four to nursing homes and two to secondary hospitals. Comorbidities were found in 120 patients (53.8%). For patients who consulted with more than one department, more consultations were for non-cancer diseases than cancer. Seventy-three patients had a do-not-resuscitate order. Conclusion: For treatment of cancer patients, it is needed to establish a cooperation system among medical institutions and provide comprehensive management including treatment of comorbidities.