• Clinical and Experimental Pediatrics
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• 제45권9호
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• pp.1150-1154
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• 2002

WPW 증후군은 발작성 상실성 빈맥을 유발할 수 있는데 매우 드물게 가족 내 동시 발생이 보고되고 있다. 그런데 최근 유전자 연구에 의해 가족 내 동시 발생된 WPW 증후군의 경우 PRKAG2 유전자의 변이가 보고된 바 있다. 저자들은 빈맥 등 특이할 만한 임상증상을 보이지 않았던 한가족에서 3명의 자녀 중 남매 간에 WPW 증후군의 심전도 소견을 동시에 나타낸 증례를 보고하면서 PRKAG2 유전자 검사 소견을 분석하였는데 이 유전자의 변이 소견이 환아와 가족 내에서 관찰되지 않아 본 증례의 원인으로 다른 유전자의 변이 가능성을 보고하는 바이다.

• Journal of Chest Surgery
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• 제22권2호
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• pp.234-245
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• 1989

Between January 1984 and December 1986, sixty nine patients, aged 16 months to 25 years [mean age 10.05*6.40 years], underwent total correction of tetralogy of Fallot in Kyungpook national university hospital. In 66 hospital survivors, 30 patients were followed up for 12 to 48 months [mean 30.10*10.26 months]. These 30 patients were classified in two groups, TAP [transannular patch] and Non-TAP group. There were 9 patients in TAP group, and 21 in Non-TAP group. There were no significant differences between two groups in terms of age at operation, follow up duration, ACC time, and bypass time. All patients were evaluated by two dimensional echocardiography, Doppler echocardiography, standard 12-lead electrocardiography, and plain chest X-ray. Right ventricular systolic pressure, pulmonary arterial systolic pressure, pressure gradient between the right ventricle and the pulmonary artery, presence or absence of pulmonary regurgitation and its grading, fractional shortening of the left ventricle, and Qp/Qs in case of remnant ventricular septal defect were obtained by echocardiographic examination. Cardiothoracic ratio was measured by plain chest film, and ventricular dysrrhythmia was detected by electrocardiogram. Comparing the data between two groups, there was significant difference in incidence of postoperative pulmonary regurgitation [p< 0.05], 100%[9/9] in TAP group and 47.6 %[10/21] in Non-TAP group, but all the regurgitations were not severe. There were no significant differences in other comparisons, despite of higher incidence of cardiomegaly in TAP group [CT ratio: 59.3*5.3% VS 54.7*6, 4 %].

• 대한수의학회지
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• 제56권3호
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• pp.161-166
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• 2016

Hyperadrenocorticism (HAC) is a common endocrinopathy among dogs that causes multisystemic signs. This study was conducted to evaluate cardiocirculatory, biochemical, and hemostatic parameters in dogs with HAC at diagnosis, in addition to verifying whether abnormal parameters could be controlled by initial treatment with trilostane. Fifteen dogs with HAC were assessed by systolic blood pressure measurement, electrocardiography, Doppler echocardiography, serum concentration of troponin I, and biochemical and hemostatic profile at diagnosis and after trilostane therapy. Unlike biochemical parameters, hemostatic and cardiocirculatory parameters were not significantly influenced by the onset of treatment. The authors believe that clinical treatment with trilostane for 3 to 4 months might not be sufficient for the stabilization of cardiocirculatory abnormalities such as hypertension. Therefore, dogs with HAC must receive cardiocirculatory monitoring at diagnosis and during drug treatment.

• Parasites, Hosts and Diseases
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• 제46권4호
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• pp.223-227
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• 2008

Changes in selected blood and serum components and electrocardiography (ECG) were investigated in 20 adults (13 females and 7 males) of water buffaloes suffering from severe theileriosis. The age of all animals used in this study ranged 1.5-5yr. Theileriosis was diagnosed by observation of parasites in the peripheral blood and the presence of schizonts in lymphocytes that were provided from swollen lymph nodes. Statistically significant decreases were observed in the means of RBC, WBC, and packed cell volume (PCV) in blood of infected animals. The means levels of sodium, calcium, phosphorus, and potassium of infected animals were lower than healthy animals, but only the decrease of potassium was significant. The mean serum activities of aspartate transferase and alanine aminotransfrase were significantly higher than in un infected animals. Three cases had atrial premature beat, 2 cases had sinus tachycardia, 2 had sinus arrhythmia, and 1 had first degree of atrioventricular block in ECG. The present study showed that T. annulata infection in cattle is associated with hematological and biochemical, and ECG changes.

• Journal of Chest Surgery
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• 제24권4호
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• pp.421-427
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• 1991

Atrial fibrillation[Af] is closely related to thrombus in left atrium, systemic embolism, and loss of the contribution of atrial contraction to cardiac output. Therefore maintenance of sinus rhythm[SR] is undoubtedly hemodynamically superior to Af in the clinical course of mitral valvular disease especially in the unstable period immediately after surgery. In this article, the conversion rate and the factors influencing the conversion of Af to SR after surgery were studied. Ninety-three patients with mitral valvular replacement at Chungnam National University Hospital were analysed with electrocardiography before and after surgery during the period from June 1985 to June 1990. Eighty patients presented Af before surgery. Twenty-four[30Yo] of the patients were converted to SR[A group] and fifty six presented continuous Af after surgery[B group]. The duration of preoperative Af, preoperative left atrial dimension[LAD], preoperative functional status[NYHA classification] and cardiothoracic[CT] ratio were factors influencing the conversion of Af to SR after surgery. The mean preoperative duration of Af was 3.5$\pm$2.6yr in group A and 7.6$\pm$4.9yr in group B. The mean preoperative LAD was 53. 7$\pm$9.4mm in group A and 62.5$\pm$11.2mm in group B. Before surgery, eleven patients[46%] were belong to NYHA class I, II in group A and eight[14%] in group B. The preoperative CT ratio was 62$\pm$6% in group A and 69$\pm$8% in group B.

• Neonatal Medicine
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• 제16권2호
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• pp.239-243
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• 2009

다소성 심방 빈맥은 신생아에서 드물게 발생하며 진단하기에 어려워 심방 조동으로 오인되기도 한다. 치료가 어려우나 생후 1년 안에 자연적으로 사라지는 경우도 있다. 불규칙한 심방 빈맥을 가진 신생아에게 직접 제작한 경식도 전극을 이용한 심전도를 시행하여 다소성 심방 빈맥을 진단하였다. Propranolol은 치료에 효과적이지 않았으나 digoxin과 sotalol 투여 후 환자는 점차 동리듬으로 회복되었다. 신생아에서 경식도 전극을 이용하여 다소성 심방 빈맥을 진단하였던 1례를 보고한다.

• 한국정보통신학회논문지
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• 제15권10호
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• pp.2265-2271
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• 2011

본 논문에서는 인간의 신체와 관련된 상황정보를 기반으로 한 u-헬쓰케어 시스템 설계 연구이다. 최근 운동 클럽 에서 전문 트레이너와 함께 체계적인 운동을 하는 것이 웰빙에서 이슈가 되었지만, 그중에서 기존의 헬쓰케어 시스템은 단지 고정된 시스템에서 현재 자신의 혈압과 맥박, 심전도, 근전도 등의 일반적인 정보만 제공하기 때문에 장시간이나 장기간의 운동을 하기에는 시간이 지날수록 흥미도가 떨어지고, 사용자 자신에 맞는 관리를 하기가 어렵다. 본 논문에서 개발된 u-헬쓰케어 시스템은 센서 네트워크와 DB를 접목한 상황 인식 시스템을 이용하여 자신의 현재 상태와 운동 진행 상태를 분석한 맞춤 운동을 할 수 있는 상황인식 기반의 서비스를 제공하는 u-헬쓰케어 시스템을 설계 개발 하였다.

• 전기학회논문지
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• 제65권5호
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• pp.857-861
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• 2016

In this study, we proposed a new method that can be measure ECG (Electrocardiography) and PPG (Photoplethysmography) in realtime on the site of the wrist for check the state of health in daily life. For convenience measurement of ECG the lead I method was used on the wrist, and omit the reference junction ECG I was measured in the right hand and the left hand of the potential difference. Then the measured electrocardiogram was amplified by the differential amplifier and the signals were passed HPF, LPF, and BPF filters. For removing the PPG's noise from the Motion artifact and temperature, we apply the reflective photoelectric volume pulse wave measurement method using green LED as a light source. The circuits was designed to be able to check the waveform using higher active amplification method at weak signals. For the validation of our device, the measured signals were compared with E2-KIT on same time. The results shows that the error does not exceed the maximum one, most of the data is confirmed to be issued Peak inspection of the same number.

• 전기학회논문지
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• 제58권5호
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• pp.1050-1056
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• 2009

Heart Rate Variability(HRV) is a parameter that represents monitoring variability of time intervals between R-peak in electrocardiography. HRV serves to various applications, such as indices of autonomic functions, prediction of cardiac sudden death, assessment of stress and emotional, etc. However, as measuring R-peak in ECG needs at least 3-electrodes, and it is inconvenient for end users. In this paper, we suggested the modified laplacian electrodes for measuring HRV at one-point, which are producted by MEMS fabrication and have the two circular electrodes on the pad. For optimal position and direction, we performed an experiment that compared with pearson correlation coefficient and the amplitude of signals, between standard lead II and proposed electrodes. We analyzed the HRV parameters, such as standard deviation of the NN interval(SDNN), high frequency(HF), low frequency(LF), LF/HF ratio. The result showed that the average correlation coefficient and amplitude are 0.967 and 0.685 mVpp at the position 2. The coeffiecient correlation between the standard HRV and proposed electrode-HRV is 0.999

• Journal of Chest Surgery
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• 제22권3호
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• pp.436-447
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• 1989

The effect of Glutamate to myocardial toxicity induced by doxorubicin was studied with 20 male rats. 20 rats divided into 4 subgroups, 1st group was taken for normal control group without any treatment, 2nd group was injected with only doxorubicin, 3rd group was injected with L-glutamate and doxorubicin, and 4thd group was injected with only L-glutamate [all injections were done intraperitoneally]. Observations were made to each group on their gross findings, body weight, and electrocardiography, complete blood count and serum level of creatine phosphokinase. The results were as follows; l. In 1st group, we found no changes. 2. In 2nd group, there were many changes which were loss of body weight, dehydration, loss of body hair, diarrhea and death, in addition, elevation of CPK-MB isoenzyme and changes in EKG due to myocardial damage, leukopenia, thrombocytopenia were also found. 3. In 3rd group, there were more toxic effects containing 2 death cases, compared to 2nd group. 4. In 4th group, we found no specific changes except weight gain. These results suggest that L-glutamate which is intermediate of Krebs cycle may worsen the doxorubicin-induced myocardial toxicity.