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Two Cases of Wolff-Parkinson-White Syndrome in a Family  

Joo, Chan Uhng (Department of Pediatrics, Medical School, Chonbuk National University, Institute of Cardiovascular Research)
Lim, So Hee (Department of Pediatrics, Medical School, Chonbuk National University, Institute of Cardiovascular Research)
Hwang, Pyung Han (Department of Pediatrics, Medical School, Chonbuk National University, Institute of Cardiovascular Research)
Publication Information
Clinical and Experimental Pediatrics / v.45, no.9, 2002 , pp. 1150-1154 More about this Journal
Abstract
Wolff-Parkinson-White(WPW) syndrome is characterized by electrographic evidence of ventricular preexcitation, which predisposes to supraventicular arrhythmias. Familial occurrence of WPW syndrome is uncommon. We observed two affected siblings in a family. Five members of the family underwent 12-lead electrocardiography and echocardiography. Although known genetic abnormality of the 7q34-q36(PRKAG2) for the familial WPW syndrome was evaluated, the mutation was not detected in this family. Other unknown mutations responsible for this familial WPW syndrome were suggested.
Keywords
Wolff-Parkinson-White syndrome; Family;
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