• Title/Summary/Keyword: efficacy rate

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Studies on the Efficacy of Combined Preparation of Crude Drug(XXXIII) -The Effect of Kamiondam-tang on the Cardiovascular System and Sedative Action- (생약(生藥) 복합제제(複合製劑)의 약효(藥效) 연구(硏究)(제33보)(第33報) -가미온담탕(加味溫膽湯)의 약효(藥效)-)

  • Lee, Kyung-Sub;Hong, Nam-Doo;Kim, Nam-Jae;Cho, Young-Whan
    • Korean Journal of Pharmacognosy
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    • v.17 no.4
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    • pp.280-285
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    • 1986
  • In order to investigate the effect of Kamiondam-tang on the cardiovascular system and sedative action, pharmacological studies have been carried out with water extract. The results of this investigation were summarized as follows; The sedative action was significantly recognized in mice. Vasodilative action in rabbit peripheral blood vessel and hypotension in anesthetized rabbit were remarkably recognized. Inhibitory effect of cardiac systolic action was recognized by Straub method in frogs.

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A Study of assessment criteria and reliability improvement for power supply of electrodeless fluorescent lamp (고효율 무전극형광등용 전원장치의 평가기준 및 신뢰성향상 연구)

  • 함중걸;신종욱
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2002.11a
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    • pp.181-185
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    • 2002
  • This paper gives an assessment criteria and reliability improvement for high frequency power supply of high efficacy electrodeless fluorescent lamp. The electrodeless fluorescent lamp system consist of electrodeless fluorescent lamp, high frequency power supply and lighting fixtures. The high frequency power supply has a shortest life at the system. Therefore It is need to assess the Failure Rate or Mean Time To Failure(MTTF) for the high frequency power supply of electrodeless fluorescent lamp system and improve the reliability at design. We suggest the assessment criteria and improve methods of the reliability on the design basis for the electodeless fluorescent system.

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Endoscopic treatment of vesicoureteral reflux in pediatric patients

  • Kim, Jong Wook;Oh, Mi Mi
    • Clinical and Experimental Pediatrics
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    • v.56 no.4
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    • pp.145-150
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    • 2013
  • Endoscopic treatment is a minimally invasive treatment for managing patients with vesicoureteral reflux (VUR). Although several bulking agents have been used for endoscopic treatment, dextranomer/hyaluronic acid is the only bulking agent currently approved by the U.S. Food and Drug Administration for treating VUR. Endoscopic treatment of VUR has gained great popularity owing to several obvious benefits, including short operative time, short hospital stay, minimal invasiveness, high efficacy, low complication rate, and reduced cost. Initially, the success rates of endoscopic treatment have been lower than that of open antireflux surgery. However, because injection techniques have been developed, a recent study showed higher success rates of endoscopic treatment than open surgery in the treatment of patients with intermediate- and high-grade VUR. Despite the controversy surrounding its effectiveness, endoscopic treatment is considered a valuable treatment option and viable alternative to long-term antibiotic prophylaxis.

Harmonic Elimination and Reactive Power Compensation with a Novel Control Algorithm based Active Power Filter

  • Garanayak, Priyabrat;Panda, Gayadhar
    • Journal of Power Electronics
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    • v.15 no.6
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    • pp.1619-1627
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    • 2015
  • This paper presents a power system harmonic elimination using the mixed adaptive linear neural network and variable step-size leaky least mean square (ADALINE-VSSLLMS) control algorithm based active power filter (APF). The weight vector of ADALINE along with the variable step-size parameter and leakage coefficient of the VSSLLMS algorithm are automatically adjusted to eliminate harmonics from the distorted load current. For all iteration, the VSSLLMS algorithm selects a new rate of convergence for searching and runs the computations. The adopted shunt-hybrid APF (SHAPF) consists of an APF and a series of 7th tuned passive filter connected to each phase. The performance of the proposed ADALINE-VSSLLMS control algorithm employed for SHAPF is analyzed through a simulation in a MATLAB/Simulink environment. Experimental results of a real-time prototype validate the efficacy of the proposed control algorithm.

Effect of MgO Deposition Condition on the Discharge Characteristic of AC-PDP (AC-PDP에서 MgO 증착조건에 따른 패널특성 연구)

  • Jeong, Joo-Young;Cho, Sung-Yong;Lee, Don-Kyu;Lee, Hae-June;Lee, Ho-Jun;Park, Chung-Hoo
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.8
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    • pp.1566-1571
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    • 2009
  • The discharge electrodes in ac PDP are coated with dielectric layer, and transparent MgO thin films are deposited on the dielectric layer. The main role of the MgO thin films in ac PDP is to protect the dielectric layer from sputtering by ion bombardment in the glow-discharge plasma. An additional important role of the MgO thin film is the high secondary electron emission coefficient which leads the low firing voltage and low cost of the PDP. In this paper, we investigated the relations of the crystal orientation about deposition thickness, deposition rate, temperature of substrate, and distance between the MgO tablet and the substrate. Additionally, we investigated the discharge characteristics of the AC PDP using nano-powder MgO tablet

Clinical Application of $^{18}F-FDG$ PET in Alzheimer's Disease (알쯔하이머병(Alzheimer's disease)에서 FDG PET의 임상이용)

  • Ryu, Young-Hoon
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.sup1
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    • pp.166-171
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    • 2008
  • PET of the cerebral metabolic rate of glucose is increasingly used to support the clinical diagnosis in the examination of patients with suspected major neurodegenerative disorders, such as Alzheimer's disease. $^{18}F-FDG$ PET has been reported to have high diagnostic performance, especially, very high sensitivity in the diagnosis and clinical assessment of therapeutic efficacy. According to clinical research data hitherto, $^{18}F-FDG$ PET is expected to be an effective diagnostic tool in early and differential diagnosis of Alzheimer's disease. Since 2004, Medicare covers $^{18}F-FDG$ PET scans for the differential diagnosis of fronto-temporal dementia (FTD) and Alzheimer's disease (AD) under specific requirements; or, its use in a CMS approved practical clinical trial focused on the utility of $^{18}F-FDG$ PET in the diagnosis or treatment of dementing neurodegenerative diseases.

Radiation Therapy for Loco regional Recurrence of Adenocarcinoma of The Rectum (국소재발 직장암의 방사선 치료)

  • Cho K. H.;Seong J. S.;Suh C. O.;Kim G. E.
    • Radiation Oncology Journal
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    • v.2 no.2
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    • pp.237-243
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    • 1984
  • Thirty Patients with loco-regional recurrence following curative surgery for adenocarcinoma of the rectum were retrospectively evaluated to determine factors influencing survival and the efficacy of radiation therapy. In this review of 30 patients undergoing radiation therapy, more than 50 percent(17/30) had definite symptomatic and objective response. Ninety percent of patients(27/30) received significant palliation. Over all 2 year survival rate was $7.4\%$ and their median survival was 13.0 months. Grade of response and Sex were statistically related to survival.

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Aerodynamic Characteristics of Whispered and Normal Speech during Reading Paragraph Tasks (문단낭독 시 속삭임 발화와 정상 발화의 공기역학적 특성)

  • Pyo, Hwayoung
    • Phonetics and Speech Sciences
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    • v.6 no.3
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    • pp.57-62
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    • 2014
  • The present study was performed to investigate and discuss the aerodynamic characteristics of whispered and normal speech during reading paragraph tasks. 39 normal females(18-23 yrs.) read 'Autumn' paragraph with whispered and normal phonation. Their readings were recorded and analyzed by 'Running Speech' in Phonatory Aerodynamic System(PAS) instrument. As results, during whispered speech, the total duration was longer and the numbers of inspiration were more frequently shown than normal speech. The Peak expiratory and inspiratory rate were higher in normal speech, but the expiratory and inspiratory volume were higher in whispered speech. By correlation analysis, both whispered and normal speech showed significantly high correlation between total duration and expiratory/inspiratory airflow duration; numbers of inspiration and inspiratory airflow duration; expiratory and inspiratory volume. These results show that whispered speech needs more respiratory effort but shows poorer aerodynamic efficacy during phonation than normal speech.

Hemodynamic Modeling of the Pulsatile Cardiac Pulmonary Perfusion for the Patient's Heart (환자의 박동형 심장의 폐순환 혈류 모델링에 대한 연구)

  • Kim, J.S.;Kim, M.S.;Choi, S.W.
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.1679-1682
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    • 2008
  • Pulsatile Extracorporeal Membrane Oxygenation(ECMO) can mitigate the heart load and raise the patient's blood perfusion. But If the ECMO pulsate the blood flow during the systolic period, It can burden to the patient's heart. To avoid the heart injury, we have to consider the relation between output of ECMO, hemodynamic states and heart movement. To raise the efficacy of the pulsatile ECMO, we investigated the coronary perfusion, cardiac muscle tension and hemodynamic states during the ECMO perfusion by using the mathematical model of human blood circulatory system and ECMO. The outflow data of the pulsatile ECMO(T-PLS, Bioheartkorea, Korea) was obtained in vitro experiments. According to the phase and pumping rate of the ECMO, the heart's load and coronary perfusion could be adjusted to the proper levels. The results of the human- ECMO lumped parameter model showed that the synchronizing operation of the pulsatile ECLS can be helpful at stabilizing the patient's hemodynamic states.

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Video-assisted Thoracoscopic Surgery for Treatment of Earlystage Non-small Cell Lung Cancer

  • Fan, Xing-Long;Liu, Yu-Xia;Tian, Hui
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.2871-2877
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    • 2013
  • Objectives: To evaluate the safety, efficacy, and invasiveness of lobectomy by video-assisted thoracoscopic surgery (VATS) in the treatment of stage I/II non-small cell lung cancer (NSCLC). Methods: A total of 148 patients presenting with Stage I or II NSCLC were enrolled into our study, comprising 71 who underwent VATS and 77 patients undergoing conventional thoracotomic lobectomy, in combination with systematic lymph node resection. Results: It was found that VATS was superior to conventional thoracotomy in terms of the duration of surgery, intraoperative blood loss, frequency of the need to administer postoperative analgesia, thoracic intubation indwelling time, post-operative hospital stay, and survival rate (P<0.05). We saw no obvious difference in the number of resected lymph nodes with either approach. Conclusions: VATS lobectomy is a safe and reliable surgical approach for the treatment of Stage I/II NSCLC, characterized by significantly minimal invasiveness, rapid post-operative recovery, and markedly lower loss of blood.