• Proceedings of the Korean Operations and Management Science Society Conference
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• 2008.10a
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• pp.353-358
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• 2008

The ocean has settled down in human mind as a territory and a leisure space from which anyone enjoys and takes a benefit under the national sovereignty, as the new era of Sea comes. In addition, because the population engaged in marine activities has rapidly increased, the number of marine accidents consequently has grown up as well. In this reason, currently it has been highlighted to devise safety measures to prevent large scale accidents or disasters on the oceans. Therefore, this thesis firstly points out issues and problems of current search and rescue operations, and secondly studies three primary factors of the search and rescue operations, which are decision of search range, decision of search asset, and decision of search duration. Finally, the thesis suggests a theoretical foundation of the search and rescue operations by applying the result of studies and the marine search theory through a theoretical approach to reasonable standards.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10991-10992
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• 2015

Tobacco is a well known cause of death worldwide. With existing comprehensive laws and various other measures for tobacco control, the mortality and morbidity due to tobacco usage have unfortunately not been reduced. A large number of tobacco users have altered their pattern of tobacco use after the gutka ban. Traditional gutka is sold in the open market in a pre-mixed format. Manufacturers are supplying pan masala and tobacco in separate pouches as there is no restriction for sale of pan masala and tobacco individually in many states. Although most of the population is aware of the health hazards of tobacco, it is necessary to develop an effective structured strategy. Tobacco control programs need to be strengthened by separate tobacco control measures at various levels.

• Journal of the Korean Institute of Rural Architecture
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• v.5 no.2
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• pp.52-61
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• 2003

It is to be profound that the population in rural area has been decreased, as a greate number of people have moved to urban area, in accordance with rapidly civilization in Korea. In 1990's years, it is become to as the social problem. As a result, many elementary schools in rural area were to be closed. Closed school facilities were used as a community facilities in rural area, but that reusing rates and method is not systematic. A decline in the work of construction is need to involve with the interior and remodeling. The purpose of this study is to suggest the effective employment and using methodology as a community facilities of closed school in rural area.

• Clinical and Experimental Pediatrics
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• v.53 no.4
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• pp.465-470
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• 2010

The number of long-term survivors is increasing in the western countries due to remarkable improvements in the treatment of childhood cancer. The long-term complications of childhood cancer survivors in these countries were brought to light by the childhood cancer survivor studies. In Korea, the 5-year survival rate of childhood cancer patients is approaching 70%; therefore, it is extremely important to undertake similar long-term follow-up studies and comprehensive long-term care for our population. On the basis of the experiences of childhood cancer survivorship care of the western countries and the current Korean status of childhood cancer survivors, long-term follow-up study and long-term care systems need to be established in Korea in the near future. This system might contribute to the improvement of the quality of life of childhood cancer survivors through effective intervention strategies.

• Journal of Korean Society of Water and Wastewater
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• v.18 no.2
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• pp.247-253
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• 2004

Major species of Lake Deganuma has varied depending on the season. Namely, there are Micractinium pusillum, chlorella., Scenedesmus sp. shown up in spring season, Microcystis aeruginosa, Microcystis wesenbergii, Anabena spiroides in summer and autumn season and Cyclostephanos invisitatus, Diatoma in winter season in the Lake. As the number of plankton increased, the zeta potential on their surface of them decreased. For this reason, they were dispersed in the lake though the population increased. Zeta potential of M. aeruginosa showed -20mV when their outer size got smaller. As for coagulant dosing in DAF, large amount of coagulant was effective to get lots of sludge during water treatment.

• IMMUNE NETWORK
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• v.2 no.1
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• pp.1-5
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• 2002

Estimated number of adults and children newly infected with HIV-1 during 2001 alone is 5 million in total. An effective vaccine, in addition to education & public health approaches, has been believed to be the best option to stop the HIV-1 transmission, especially for developing countries. Among AIDS vaccine candidates, DNA vaccine is relatively safe and, in a certain extent, mimics some attributes of live attenuated vaccine, with regard to in vivo gene expression & the type of immunity induced. We recently demonstrated that DNA vaccines expressing SIVmac239 structural and regulatory genes, augmented with coadministration of IL-12 mutant induced the strongest T cell responses, resulting in low to undetectable setpoint viral loads, stable $CD4^+$ T cell counts, and no evidence of clinical diseases or mortality by day 420 after challenge. This finding is the second demonstration, following the protective result of live attenuated SIV vaccine in SIVmac-rhesus monkey model, which was known to have safety problem. So, our DNA vaccines could give a significant impact on HIV-1 epidemic by slowing or stopping the spread of HIV-1, leading to eventual eradication of HIV-1 and AIDS in the population.

• Bulletin of the Korean Chemical Society
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• v.31 no.12
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• pp.3777-3781
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• 2010

The anticancer effect and apoptotic mechanism of a novel indole derivative AC-264, a lead derived from a chemical library, were investigated in human promyelocytic leukemia HL-60 cells. HL-60 cells treated with AC-264 at various concentrations showed the morphological features of apoptosis, such as plasma membrane blebbing and cell shrinkage. AC-264 exhibited cytotoxic effect in various cancer cell lines with different degrees of potency. Especially, AC-264 was effective on increasing the population of apoptotic cells in HL-60 cells, as detected by the number of cells stained with Annexin V and PI. Furthermore, AC-264 activated caspase-3 enzyme activity and induced internucleosomal DNA fragmentation. These results indicated that AC-264 produces anti-cancer effect via apoptotic cell death by activating caspase-3 and inducing internucleosomal DNA fragmentation in HL-60 cells.

• Journal of The Korea Institute of Healthcare Architecture
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• v.10 no.2
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• pp.7-18
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• 2004

As a society advances and develops more rapidly, there is a corresponding increase in an aging population; and therefore, transportation and transportation needs develop in a complicated way. In these times, medical rehabilitation services are required and the demands for these services will increase as time passes. Moreover, the scope of disability as defined by the government has been expanded owing to the welfare policy for the disabled. Therefore, the number of disabled who require medical services is on the rise. Along with an increase in medical rehabilitation demands, the necessity for medical rehabilitation increases as well and its role becomes more diverse on a wider spectrum. However, architectural studies on rehabilitation facilities have been insufficient and there are many problems currently in facilities operations. This study aims to present a spatial organization system along with required space that would form the basis for the most effective spatial plan and facility operation for rehabilitation hospitals.

• Journal of Yeungnam Medical Science
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• v.40 no.2
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• pp.123-135
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• 2023

Advances in perinatal and pediatric intensive care and recent advances in mechanical ventilation during the last two decades have resulted in an exponential increase in the number of children undergoing home mechanical ventilation (HMV) treatment. Although its efficacy in chronic respiratory failure is well established, HMV in children is more complex than that in adults, and there are more considerations. This review outlines clinical considerations for HMV in children. The goal of HMV in children is not only to correct alveolar hypoventilation but also to maximize development as much as possible. The modes of ventilation and ventilator settings, including ventilation masks, tubing, circuits, humidification, and ventilator parameters, should be tailored to the patient's individual characteristics. To ensure effective HMV, education for the parent and caregiver is important. HMV continues to change the scope of treatment for chronic respiratory failure in children in that it decreases respiratory morbidity and prolongs life spans. Further studies on this topic with larger scale and systemic approach are required to ensure the better outcomes in this population.

• Journal of applied mathematics & informatics
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• v.41 no.5
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• pp.1017-1035
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• 2023

In this paper, we construct a monkeypox model which is similar to smallpox infection. It is caused by a monkeypox virus which is related to Poxviridae family. It will occur mostly in West African communities and in remote Central. We develop a system of differential equations for an SEIR (Suspected, Exposed, Infected and Recovered) model and analyze the outbreak of monkeypox disease and its effect on United States(US) population. We establish theorems on asymptotical stability conditions for endemic equilibrium and disease-free equilibrium. The basic reproduction number R₀ has been determined using next generation matrix. We expect that this study will be effective at controlling monkeypox spread in United States. Our goal is to see whether monkeypox can be controlled and destroyed by smallpox vaccination. We find that monkeypox is controllable and can be fully destroyed in disease free state by vaccination. However, in the endemic state, monkeypox cannot be destroyed by vaccination alone.