• Korean Journal of Clinical Pharmacy
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• v.30 no.3
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• pp.196-205
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• 2020

Background: The indication of denosumab for osteoporosis was expanded from second-line to first-line therapy in 2019. The aim of this study was to evaluate the efficacy of denosumab as both first- and second-line therapy in postmenopausal women with osteoporosis and osteopenia with risk factors by using the Fracture Risk Assessment Tool (FRAX). Methods: We conducted a medication use evaluation of denosumab in 98 patients who had been treated three or more times for osteoporosis or osteopenia at Chungnam National University Hospital from July 1^st, 2017 to January 31^st, 2020. Risk factors were identified using quantitative N-gram analyses of FRAX estimations. Patient information, including menopause status and results of bone mineral density tests (T-score), was obtained from electronic medical records. Results: Age, body mass index (BMI), prior medication use, and T-score were identified as risk factors and were included as variables in the evaluation of denosumab use. Since no significant differences were detected between groups, denosumab is likely effective regardless of age or BMI. In addition, no significant difference was detected in T-scores following denosumab treatment, between groups who took bisphosphonates and selective estrogen receptor modulators (SERMs) with denosumab as first-line therapy for postmenopausal osteoporosis. Denosumab may, therefore, be effective as second-line therapy. Conclusion: Efficacy of denosumab was evaluated in postmenopausal women with osteoporosis. Denosumab may be used as first- and second-line therapy regardless of age, BMI, and prior use of bisphosphonates and SERMs.

• Korean Journal of Digital Imaging in Medicine
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• v.6 no.1
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• pp.31-40
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• 2003

Purpose : In a PACS(Picture Archiving Communications System) environment, which is a very important component in a digital medical environment, the compression of digital medical images is a necessary and effective feature. In a current system where JPEG is applied to the compression of medical images, this study is to examine effectiveness and suitability when the JPEG2000, a more advanced compression algorithm for still images, is applied to the compression of medical images. In this thesis, we attempt to address the compressibility for effective clinical usage when compressing medical images, applying the objectivization of clinical evaluation as a function of compressibility. In the experiment al method, the compression was applied at a fixed rate using JPEG2000, and the n the result was compared with compressed images by JPEG. Method : For the performance evaluation, we choose SNR(Signal to Noise Ratio) measurement of an objective evaluation of definition and analyze a subjective evaluation by the ROC(Receiver Operating Characteristic) method. The results of the experiment showed that in the case of JPEG2000 there is hardly any distortion of images, even at high compression ratio(100:1), while regarding noise, the SNR remains around about 40dB, which is also relatively high. Before reading by reference to evaluative materials concerning objective compressed images, it is impossible to apply high compression to images : however, after reading, this can be applied to images that have already existed for some time.

• The Journal of the Korea Contents Association
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• v.20 no.1
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• pp.573-580
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• 2020

The purpose of this study was to explore and to suggest the effective teaching methods for university students to improve their speaking abilities through peer assessment-feedback and self assessment-feedback based presentation and debate class. The objects and content of the study were the students who took a class "Reading and Communication" of H university, and here examine closely the speaking activities and their effects during the integrated activities of 'reading, speaking and writing'. In speaking education peer and self assessment feedback is to form an emotional consensus among the students and encourage active participation, and enable self-discovery and communication learning to students. As a result of the study, it was found that the variety speaking practice had a very positive effect on the attitude of speaking and the psychological aspect, and it was confirmed that the evaluation and feedback activities had a meaningful learning effect on the students. Effective speech education and guidance measures should be continuously studied and developed.

• Journal of the Korean Geotechnical Society
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• v.23 no.8
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• pp.47-57
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• 2007

In this study, the analysis of density characteristics of some dredged and reclaimed ground sites, which is necessary for liquefaction evaluation of a dredged and reclaimed ground, was conducted. From analyzing a simplified liquefaction potential evaluation using SPT-N values which have been applied as domestic earthquake-resistant design criterion, improvement scheme is suggested. Based on the analysis result of density characteristics, it was found out that the relative density and the intial N-value ranged respectively $40{\sim}50%\;and\;5{\sim}8$. In the case of applying Liao & Whitman's equation to correct effective overburden pressure, liquefaction resistance of the upper ground that is relatively weaker than that of lower ground is overestimated. So, Skempton's equation is recommended. And the N value with depth which is applied for design process should be estimated by the exponential equation, $N=1.35{\sigma}'^{0.75}$.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.4
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• pp.193-207
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• 2021

As Deepfakes phenomenon is spreading worldwide mainly through videos in web platforms and it is urgent to address the issue on time. More recently, researchers have extensively discussed deepfake video datasets. However, it has been pointed out that the existing Deepfake datasets do not properly reflect the potential threat and realism due to various limitations. Although there is a need for research that establishes an agreed-upon concept for high-quality datasets or suggests evaluation criterion, there are still handful studies which examined it to-date. Therefore, this study focused on the development of the evaluation criterion for the Deepfake video dataset. In this study, the fitness of the Deepfake dataset was presented and evaluation criterions were derived through the review of previous studies. AHP structuralization and analysis were performed to advance the evaluation criterion. The results showed that Facial Expression, Validation, and Data Characteristics are important determinants of data quality. This is interpreted as a result that reflects the importance of minimizing defects and presenting results based on scientific methods when evaluating quality. This study has implications in that it suggests the fitness and evaluation criterion of the Deepfake dataset. Since the evaluation criterion presented in this study was derived based on the items considered in previous studies, it is thought that all evaluation criterions will be effective for quality improvement. It is also expected to be used as criteria for selecting an appropriate deefake dataset or as a reference for designing a Deepfake data benchmark. This study could not apply the presented evaluation criterion to existing Deepfake datasets. In future research, the proposed evaluation criterion will be applied to existing datasets to evaluate the strengths and weaknesses of each dataset, and to consider what implications there will be when used in Deepfake research.

• Korean Journal of Health Education and Promotion
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• v.20 no.4
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• pp.95-109
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• 2003

Tobacco use is the most readily preventable cause of premature death； it is a worldwide problem, with a significant impact on heath and well-being. In order to design an effective tobacco education program, it is important to understand smoking patterns and the underlying factors associated with smoking in different generations such as adults or young people. Despite a general decline in the prevalence of regular smoking among adults, recent surveys commissioned by the Ministry Heath ＆ Welfare for the Republic of Korea have shown no evidence of any decline in smoking rates among young women and adolescents. The Republic of Korea has the highest adult male smoking percentage (65.1%) in the world and smoking in adolescents is still an increasing trend. Smoking in adolescents and young women is especially more dangerous, thus health education of anti-smoking directed at these groups is an important area that will benefit from using internet content that they can easily access. The purpose of this study is the evaluation of visual perception and effectiveness analysis in smoking cessation websites in promoting smoking cessation in adolescents and young women through Internet content. As a result of this project, at first we evaluated the Internet content of cyber smoking cessation programs by the evaluation criteria of web design interface. The Internet site of http：//nosmokeguide.or.kr received the most superior evaluation in the domestic Internet content for smoking cessation and the Internet site of the National Center for Tobacco-Free Kids received the most superior evaluation in the foreign Internet content for smoking cessation. This evaluation was surveyed by an expert in Internet content and user. Secondly, we developed the Internet content for cyber smoking cessation program, namely, "Dr. Smoking" that contained several menus and a database regarding anti-smoking designed in accordance with the results of this evaluation. The domain address of Dr. Smoking is http：//www.dmosmoking.com and our webpage has assorted kinds of news, information, self-diagnosis, prescription, consulting, a no-smoking mall etc. In conclusion, this project is designed to develop Internet content for the most effective smoking cessation program and to contribute to eliminating smoking from our society. We also will try to develop and upgrade this web-site in order to help a smoker who want to quit smoking and diminish the physical and socioeconomic harm from smoking.m smoking.

• Imaging Science in Dentistry
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• v.43 no.3
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• pp.145-151
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• 2013

Purpose: This study was performed to evaluate and compare the radiopacity of dentin, enamel, and 8 restorative composites on conventional radiograph and digital images with different resolutions. Materials and Methods: Specimens were fabricated from 8 materials and human molars were longitudinally sectioned 1.0 mm thick to include both enamel and dentin. The specimens and tooth sections were imaged by conventional radiograph using #4 sized intraoral film and digital images were taken in high speed and high resolution modes using a phosphor storage plate. Densitometric evaluation of the enamel, dentin, restorative materials, a lead sheet, and an aluminum step wedge was performed on the radiographic images. For the evaluation, the Al equivalent (mm) for each material was calculated. The data were analyzed using one-way ANOVA and Tukey's test (p<0.05), considering the material factor and then the radiographic method factor, individually. Results: The high speed mode allowed the highest radiopacity, while the high resolution mode generated the lowest values. Furthermore, the high resolution mode was the most efficient method for radiographic differentiation between restorative composites and dentin. The conventional radiograph was the most effective in enabling differentiation between enamel and composites. The high speed mode was the least effective in enabling radiographic differentiation between the dental tissues and restorative composites. Conclusion: The high speed mode of digital imaging was not effective for differentiation between enamel and composites. This made it less effective than the high resolution mode and conventional radiographs. All of the composites evaluated showed radiopacity values that fit the ISO 4049 recommendations.

• Imaging Science in Dentistry
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• v.40 no.1
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• pp.15-23
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• 2010

Purpose : This study was designed to compare the effective doses from low-dose and standard-dose multi-detector CT (MDCT) scanning protocols and evaluate the image quality and the spatial resolution of the low-dose MDCT protocols for clinical use. Materials and Methods : 6-channel MDCT scanner (Siemens Medical System, Forschheim, Germany), was used for this study. Protocol of the standard-dose MDCT for the orthodontic analysis was 130 kV, 35 mAs, 1.25 mm slice width, 0.8 pitch. Those of the low-dose MDCT for orthodontic analysis and orthodontic surgery were 110 kV, 30 mAs, 1.25 mm slice width, 0.85 pitch and 110 kV, 45 mAs, 2.5 mm slice width, 0.85 pitch. Thermoluminescent dosimeters (TLDs) were placed at 31 sites throughout the levels of adult female ART head and neck phantom. Effective doses were calculated according to ICRP 1990 and 2007 recommendations. A formalin-fixed cadaver and AAPM CT performance phantom were scanned for the evaluation of subjective image quality and spatial resolution. Results : Effective doses in ${\mu}Sv$ ($E_{2007}$) were 699.1, 429.4 and 603.1 for standard-dose CT of orthodontic treatment, low-dose CT of orthodontic analysis, and low-dose CT of orthodontic surgery, respectively. The image quality from the low-dose protocol were not worse than those from the standard-dose protocol. The spatial resolutions of both standard-dose and low-dose CT images were acceptable. Conclusion : From the above results, it can be concluded that the low-dose MDCT protocol is preferable in obtaining CT images for orthodontic analysis and orthodontic surgery.

• The Journal of Korean Association of Computer Education
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• v.14 no.1
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• pp.137-146
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• 2011

Edward de Bono's six thinking hats is effective to increase the excellence of the thinking and cultivate divergent thinking. In particular, this method is effective in finding a reasonable solution through analyzing issue from a variety of perspective. In this paper, we developed the system for an effective debate learning that student's own ideas based on six thinking hats are shared and expressed in speech and images through Android devices sensors. We analyzed the tools and guidelines by making design structural model for system design. The developed system was evaluated by the teacher through demonstration and practice and we analyzed through evaluation results the effectiveness and the improvement of the system. The evaluation results were analysed that the developed system is more effective improve motivation and debate ability than web based debate learning system.

• Spatial Information Research
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• v.18 no.4
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• pp.55-64
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• 2010

Since 2004, as Ubiquitous Information Technology that is new information technology paradigm has emerged, the necessity of government's role has been raised. In order to understand the government's role model for the effective use of the Ubiquitous Information Technology, this article closely analysed the process of the information policy in Korea. To accomplish these purpose the literature review and the exploratory research were used. The intent of this study was to analyze the government's role in the process of the information policy. Following are the major findings of this study. First. the government's role in driving the new information policy must be considered for the effective adopt and diffusion of the new information technology'. Second, three stages(adopt, diffusion, evaluation) are considered in the process of Korea information policy. Third, the revised government's role model is needed for the effective use of the new information technology in the future. In this study, I suggested the revised government's role model, that is consist of four stages. plan. adopt. diffusion, and performance and evaluation stage.