• Title/Summary/Keyword: effect of the mediator

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Effect of Inhibitions of Ginkgo biloba Extracts on Induction of Reactive Oxygen Species and Release of Inflammation Mediator Arachidonic Acid from U937 (U937을 이용한 활성산소 유도와 염증관련 아라키돈산 유리에 있어 은행잎 엑스의 억제 효과)

  • Kang, Sang-Mo
    • Korean Journal of Food Science and Technology
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    • v.32 no.5
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    • pp.1198-1205
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    • 2000
  • Effect of inhibitions of three kinds of Ginkgo biloba extracts(Ginkgo biloba extract, Ginkgolide A, and Ginkgolide B) on induction of reactive oxygen species and release of inflammation mediator arachidonic acid were tested. Three kinds of Ginkgo biloba extracts could not inhibit the pyrogallol auto-oxidation, but they showed the hydrogen atom donating activity in DPPH assay. When 10 ${\mu}M$ hydrogen peroxide and 400 ${\mu}g/mL$ of three kinds of Ginkgo biloba extracts were added to U937 monocytic macrophage, the induction of lipid peroxidation was not observed. The Ginkgo biloba extract showed the most powerful inhibition among the extracts. And only Ginkgolide A was good for the inhibition of the protein degradation. The release of inflammation mediator arachidonic acid was induced by adding TPA and calcimycin to U937. In this assay, even 10 ${\mu}g/mL$ of three different Ginkgo biloba extracts excellently blocked the release of arachidonic acid. Particularly, the inhibition efficiency of Ginkgolide B was about 11 times higher than that of induction, and was about 4 times higher than that of the control of noninduction. This result suggests that the release of arachidonic acid is not inhibited by the antioxidant activity of Ginkgo biloba extracts, but a pre-step of the release of arachidoinc acid is inhibited by Ginkgo biloba extracts.

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Effect of dietary protein level on bone metabolism of young and aged rats (식이 단백질 수준이 어린쥐와 나이든 쥐의 골격의 대사에 미치는 영향)

  • 조미숙
    • Journal of Nutrition and Health
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    • v.22 no.6
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    • pp.497-506
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    • 1989
  • To investigate the effect of levels of dietary protein and age on bone metabolism 40% and 5% casein were fed to the rats of 2 & 13 months of age for 12 weeks. High protein groups showed higher bone weight and Ca content than low protein groups and urinary Ca loss was increased in high protein groups but the difference disappeared gradually. A significant increase in urinary hydroxyproline excretion was noted in high protein groups of both age. Another short term study was undertaken to study if the above effect was related with renal function or PTH. Extremely high and low protein diets(60%, 6%) were fed to the rats of different ages(6wks, 6mos.) for 2 weeks, Urinary Ca excretion was significantly increased in high protein groups of young and aged rats and GFR was increased as well. There was no difference in serum iPTH levels between low and high protein groups, but it was elevated in aged rats. Alkaline phosphatase activity was higher in young rats, reflecting faster bone formation. The observed hypercalciuria in high protein groups, especially in aged rats, seems to be related to higher GFR, and PTH dose not appear to be a major mediator.

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Social Learning Effect of Leader's OCB on Follower's OCB (리더 조직시민행동의 사회적 학습 효과)

  • Kim, Boyoung;Min, Eunhong
    • Knowledge Management Research
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    • v.21 no.2
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    • pp.159-176
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    • 2020
  • According to the social learning theory, leader' organizational citizenship behavior (OCB) is a predisposing factor for follower' OCB, because they acknowledge and imitate leader as a desirable example of behaviors for organizational and individual success. We investigate social learning effect of leader OCB on follower OCB and examine the moderating role of political skill in the mediated relationship between leaders OCB and follower OCB (with followers' affective organizational commitment as the mediator). We find that follower's affective organizational commitment may mediate the relationship between leader OCB and follower OCB. Furthermore, we find that follower with high political skill may focus on the instrumental value of OCB. Political skill moderates the relationship between follower' affective organizational commitment and follower OCB. Data from 325 leader-follower dyads support the hypothesis. Theoretical and practical implications of these findings are also discussed.

Converged Study on the Factors Affecting of Care Service Personnel's Job Satisfaction: Focusing on mediator effect of supervision (돌봄서비스 제공인력의 직무만족 영향에 대한 융복합 연구 : 수퍼비전의 매개효과를 중심으로)

  • Lee, Hyoung-Ha
    • Journal of the Korea Convergence Society
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    • v.7 no.6
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    • pp.229-236
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    • 2016
  • This study attempted to identify multi-dimensional influencing factors of working condition, job stress and supervision affecting care service personnel's job satisfaction by using structural equation model. From the results of this study, first, working condition (B=.247), job stress (B=-.610) and supervision (B=.635) were analyzed to have statistically significant effects upon job satisfaction as a dependent variable. Approximately 34.9% of job satisfaction was found to be explained through variables put into research models. Second, supervision affecting job satisfaction was found to have mediation effects on job stress. It will be necessary to apply the method to effective manpower management plan through supervision in the manager education course to improve job satisfaction for social service delivery manpower as well as care service in the future.

The Effects of Celebrity's Traits on Media Engagement, Advertising Effect and Purchasing Intention in Food Service Industry (외식기업의 유명인 모델 속성이 미디어 인게이지먼트, 광고효과 및 구매의도에 미치는 영향)

  • Kim, Yung-chan;Yoon, Sung-Gil;Bang, So-Yun
    • Culinary science and hospitality research
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    • v.23 no.7
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    • pp.204-219
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    • 2017
  • The aim of this study was to examine the role of celebrity's traits on food service enterprises' media engagement, advertising effect (AD effect) and purchasing intention. Based on advance research, structural model of relationship between celebrity's traits and media engagement, AD effect and promotion of purchase was developed among the proposed constructs. Few empirical studies have been conducted to test the model. Date collection of study was from June 1st, 2017 to June 30th, distributing total of 300 issues and collecting total of 290 issues. Total of 271 questionnaires were used as the final analysis data as the nineteen questionnaires included missing information. The results can be summarized as follows: Celebrity's Traits significantly affected media engagement, AD effect and purchasing intentions. More specifically, mediating effect among the celebrity's traits and AD effect which came from media engagement was valid only if the subject of advertising effectiveness was on brands attitude. Based on the findings, theoretical and managerial implications were discussed to make one conclusion. As the media engagement was identified as a mediator between celebrity's traits and AD effect, certain brands which tend to enhance their AD effectivity should liaison proper celebrity.

The Effect of Individuals' Vulnerability to the Different Sex's Physical Attractions on Their Own Acceptance of Extramarital Relationship and Intentions of Open Marriage (이성의 신체적 매력에 대한 취약성이 본인의 혼외관계 수용성 및 개방결혼의도에 미치는 영향)

  • Lee, Hee-Jin
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.7
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    • pp.203-216
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    • 2020
  • The purpose of this study is to reveal the effects of the VDSPA(Vulnerability to the Different Sex's Physical Attraction) on IOM(the intention of open marriages), the mediating effect of the SAEMR(Self Acceptance of Extra-Marital Relationship) and the moderating effect of gender. This is an empirical research based on data analysis obtained by surveying 655. The notable findings are as follow: First, respondents' perceptions of their own extramarital affairs(M=2.284) and open marriages(M=2.175) are generally negative, but women were more negative than men. Second, both men and women were vulnerable to the physical attraction of the opposite sex(M=3.569), especially men than women. Third, the more vulnerable to the physical attraction of the opposite sex, the more receptive to their own infidelity. The more receptive to their own extramarital affair, the more clear their intention to open marriage. Lastly, in the case of women, it is confirmed that the vulnerability of the physical attraction of the opposite sex has a significant effect on the intention of an open marriage, with the acceptability of the one's own infidelity as a mediator. In the case of men, there is no mediating effect of accepting their own extramarital affairs, which proved to be a moderating effect by gender. Unlike men, in the case of women, it is concluded that 'accepting their own extramaritality is a critical factor that directly or indirectly has a significant effects on their intention to open marriage.

Mediating Effect of the Attitude on the Relationship between Subjective Norms and Voice Intention (주관적 규범과 불평행동 의도의 관계에 미치는 태도의 매개 효과)

  • Kang, Jong-Heon;Pyo, Gil-Taek
    • Culinary science and hospitality research
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    • v.13 no.2
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    • pp.12-21
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    • 2007
  • The purpose of this study was to examine the effect of subjective norms on customers' intention to engage in voice of dissatisfaction responses, the effect of subjective norms on attitude, and the mediating effect of attitude on the relationships between subjective norms and customers' intention to engage in voice of dissatisfaction responses. The simple regression analysis is used in order to estimate the effects of subjective norms on customers' intention to engage in voice of dissatisfaction responses and attitude. The mediated regression analysis is used in order to estimate the mediating role of attitude of the effect of subjective norms on customers' intention to engage in voice of dissatisfaction responses. Results of the study demonstrated that the inclusion of perceived behavioral control did significantly improve the predictability of the voice of dissatisfaction response intentions. Furthermore, the mediating analysis indicated that the influence of subjective norms was mediated by mediator. In the contests of voice behavior, the effect of subjective norms on intention was mediated by attitude.

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The Impact of Job Placement on Organizational Commitment: A Case Study of Power Plant Employees in Sumatra, Indonesia

  • DYAH, Widowati;UMAR, Nimran;AL MUSADIEQ, M.;NAYATI, Utami Hamidah
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.5
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    • pp.553-560
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    • 2022
  • This study investigates the effect of job satisfaction as a mediator of job placement on employees' organizational commitment in the Sumatra-Indonesia energy sector. Permanent personnel of a PGU unit power plant in Sumatra, Indonesia, made up the population and sample. The sampling technique used was saturated sampling of 129 employees. The research model and hypotheses were tested using multiple regression analysis. This study indicate that job placement has a significant positive effect on job satisfaction. Simultaneously, job placement does not have a significant positive effect on organizational commitment. Secondly, job satisfaction has a significant positive effect on organizational commitment and finally, job satisfaction mediates the relationship between job placement and organizational commitment. The results of this study indicate that job placement has a significant positive effect on job satisfaction. Therefore, the right job placement will lead to employee job satisfaction. Another finding is that job placement has a positive and insignificant effect on organizational commitment. Furthermore, job satisfaction has a significant positive effect on organizational commitment. The results of this study indicate that the higher the job satisfaction of the PGU unit employees in the Sumatra area, the higher the level of employee organizational commitment will be.

The Effect of Authentic Leadership and Psychological Contract Breach on Organizational Cynicism: Focusing on the Moderated Mediation of Followers' Identification with the Leader

  • Kim, Yesung;Shin, Je-Goo
    • Knowledge Management Research
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    • v.18 no.4
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    • pp.1-29
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    • 2017
  • This study sets out to verify the moderated mediation of followers' identification with the leader on the indirect effect of authentic leadership on organizational cynicism via psychological contract breach. A total of 279 responses from employees at companies with more than 500 employees and of diverse industries were used for analysis. Our findings showed that authentic leadership (X) had a negative indirect effect on organizational cynicism (Y) via psychological contract breach (M), and that this indirect effect was negatively moderated by identification with the leader, thereby identifying its role as a moderating mediator. Further verification revealed that the indirect effect ($X{\rightarrow}M{\rightarrow}Y$) was conditional upon the value of the moderating variable, where identification with the leader had a significant effect in the 25%, 50%, 75%, 90% levels, but not in the 10% level. The findings of this research empirically verified that greater exertion of authentic leadership lowers psychological contract breach among organization members and, consequently, organizational cynicism. In particular, this effect was stronger when the organization member identified him/herself more strongly with the leader. Our findings extend the body of knowledge on the relationship between authentic leadership and organizational cynicism and expands the possibilities for future research.

The Effects of Emotional Labor on Burnout: The Moderating and Mediating Effects of Flourishing in Child Care Teachers (어린이집 교사의 정서노동과 소진 간 관계에서 행복플로리시의 조절 및 매개효과)

  • Lee, Ji Yeun;Kim, Hee Yeol
    • Korean Journal of Child Studies
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    • v.37 no.4
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    • pp.169-179
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    • 2016
  • Objective: This study investigated the moderating and mediating effects of flourishing among child-care teacher's emotional labor and burnout. Methods: The participants included 243 child-care teachers in daycare centers in Jeju. To verify moderating effect of flourishing in relation between surface acting and burnout, 2-way ANOVA was used. To verify mediating effect of flourishing in relation between deep acting and burnout, the hierarchical regression and bootstrapping analyses were used. Results: First, the surface acting of emotional labors showed significantly positive effect with burnout and the deep acting of emotional labors shows significantly negative effect with burnout. And the surface acting of emotional labors shows significantly negative effect with flourishing and the deep acting of emotional labors shows significantly positive effect with flourishing. Also the flourishing shows significantly negative effect with burnout. Second, it was revealed that the flourishing plays a role as moderator in relation between surface acting and burnout. Finally, it was revealed that the flourishing plays a role as mediator in relation between deeping acting and burnout. Conclusion: This study illustrates that flourishing acts as differently in relation to emotional labor (surface acting/deep acting) and burnout.