• Steel and Composite Structures
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• v.22 no.2
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• pp.235-255
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• 2016

This paper experimentally investigated the behavior of steel frame structures of traditional-style buildings subjected to combined constant axial load and reversed lateral cyclic loading conditions. The low cyclic reversed loading test was carried out on a 1/2 model of a traditional-style steel frame. The failure process and failure mode of the structure were observed. The mechanical behaviors of the steel frame, including hysteretic behaviors, order of plastic hinges, load-displacement curve, characteristic loads and corresponding displacements, ductility, energy dissipation capacity, and stiffness degradation were analyzed. Test results showed that the Dou-Gong component (a special construct in traditional-style buildings) in steel frame structures acted as the first seismic line under the action of horizontal loads, the plastic hinges at the beam end developed sufficiently and satisfied the Chinese Seismic Design Principle of "strong columns-weak beams, strong joints-weak members". The pinching phenomenon of hysteretic loops occurred and it changed into Z-shape, indicating shear-slip property. The stiffness degradation of the structure was significant at the early stage of the loading. When failure, the ultimate elastic-plastic interlayer displacement angle was 1/20, which indicated high collapse resistance capacity of the steel frame. Furthermore, the finite element analysis was conducted to simulate the behavior of traditional-style frame structure. Test results agreed well with the results of the finite element analysis.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.6
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• pp.794-798
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• 2004

An attempt was made to improve the efficiency of growth and lactation performance of dairy heifers subjected to a stair-step growth scheme using rice straw as the sole roughage source. Twenty-four young Holstein heifers were randomly assigned to either control or test group. The control diet met the National Research Council (NRC) requirement, with heifers calving at 24 to 26 mo of age. The test group was individually fed according to a schedule of 3, 2, 4, 2, 5 and 2 mo in which feed intake was alternately 20% below or 25% above the NRC requirements. Heifers on the stair-step growth pattern gained more body weight and consumed less dry matter (10.80 and 11.22%, respectively), resulting an increasing growth efficiency compared with the control. Body condition, first estrus, first conception, services per conception and calving difficulty (data not shown) were not affected. Milk yield of the test group was 8.5% higher than that of the control group. During the early lactation period, the milk yield was significantly higher in the stair-step group than in that of the control group (p<0.05). Milk composition was not affected by compensatory growth induced by the stair-step scheme. Also, weight at calving and calf growth performance was not affected by stair-step growth. The results indicate that using rice straw as a sole roughage source in a stair-step compensatory growth scheme can contribute to the improvement of growth efficiency and early lactation performance.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.2
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• pp.198-207
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• 2018

Objective: This study investigated the association of yeast species with improved aerobic stability of total mixed ration (TMR) silages with prolonged ensiling, and clarified the characteristics of yeast species and their role during aerobic deterioration. Methods: Whole crop corn (WCC) silages and TMR silages formulated with WCC were ensiled for 7, 14, 28, and 56 d and used for an aerobic stability test. Predominant yeast species were isolated from different periods and identified by sequencing analyses of the 26S rRNA gene D1/D2 domain. Characteristics (assimilation and tolerance) of the yeast species and their role during aerobic deterioration were investigated. Results: In addition to species of Candida glabrata and Pichia kudriavzevii (P. kudriavzevii) previously isolated in WCC and TMR, Pichia manshurica (P. manshurica), Candida ethanolica (C. ethanolica), and Zygosaccharomyces bailii (Z. bailii) isolated at great frequency during deterioration, were capable of assimilating lactic or acetic acid and tolerant to acetic acid and might function more in deteriorating TMR silages at early fermentation (7 d and 14 d). With ensiling prolonged to 28 d, silages became more (p<0.01) stable when exposed to air, coinciding with the inhibition of yeast to below the detection limit. Species of P. manshurica that were predominant in deteriorating WCC silages were not detectable in TMR silages. In addition, the predominant yeast species of Z. bailii in deteriorating TMR silages at later fermentation (28 d and 56 d) were not observed in both WCC and WCC silages. Conclusion: The inhibition of yeasts, particularly P. kudriavzevii, probably account for the improved aerobic stability of TMR silages at later fermentation. Fewer species seemed to be involved in aerobic deterioration of silages at later fermentation and Z. bailii was most likely to initiate the aerobic deterioration of TMR silages at later fermentation. The use of WCC in TMR might not influence the predominant yeast species during aerobic deterioration of TMR silages.

• Journal of The Korean Astronomical Society
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• v.48 no.1
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• pp.21-55
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• 2015

If the Universe is dominated by cold dark matter and dark energy as in the currently popular ${\Lambda}CDM$ cosmology, it is expected that large scale structures form gradually, with galaxy clusters of mass $M{\geq}10^{14}M_{\odot}$ appearing at around 6 Gyrs after the Big Bang (z ~ 1). Here, we report the discovery of 59 massive structures of galaxies with masses greater than a few times $10^{13}M_{\odot}$ at redshifts between z = 0.6 and 4.5 in the Great Observatories Origins Deep Survey fields. The massive structures are identified by running top-hat filters on the two dimensional spatial distribution of magnitude-limited samples of galaxies using a combination of spectroscopic and photometric redshifts. We analyze the Millennium simulation data in a similar way to the analysis of the observational data in order to test the ${\Lambda}CDM$ cosmology. We find that there are too many massive structures (M > $7{\times}10^{13}M_{\odot}$) observed at z > 2 in comparison with the simulation predictions by a factor of a few, giving a probability of < 1/2500 of the observed data being consistent with the simulation. Our result suggests that massive structures have emerged early, but the reason for the discrepancy with the simulation is unclear. It could be due to the limitation of the simulation such as the lack of key, unrecognized ingredients (strong non-Gaussianity or other baryonic physics), or simply a difficulty in the halo mass estimation from observation, or a fundamental problem of the ${\Lambda}CDM$ cosmology. On the other hand, the over-abundance of massive structures at high redshifts does not favor heavy neutrino mass of ~ 0.3 eV or larger, as heavy neutrinos make the discrepancy between the observation and the simulation more pronounced by a factor of 3 or more.

• Journal of Korean Society of Forest Science
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• v.84 no.3
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• pp.356-360
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• 1995

Korean white pine(Pinus koraiensis S.et Z.) is one of the important silvicultural species due to its quality timber in addition to edible pine - nut production. Selective breeding method is under progress to improve growth and nut production for this species. This study was carried out to obtain genetic information necessary for establishing advanced generation seed orchard, such as genetic parameters and efficiency of early selection. Open - pollinated cones were collected from 50 plus trees. In the spring of 1986, test plantations were established at 3 different sites with 4 - year - old seedlings. Seedling height was measured from age 5 to 10 in plantations. Genetic and phenotypic correlations based on the log of the ratio of two ages (LAK) were expressed as simple regression with statistical significance($r^2=0.7862$ and 0.8256, respectively). If 20 years is presumed to mature, the most efficient age for early selection is 3 years after planting with efficiency of 1.96.

• Journal of Radiation Industry
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• v.12 no.4
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• pp.311-316
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• 2018

Average life expectancy is getting longer due to medical developments and improvements in living standards. So much so that the elderly have an increased risk of developing osteoporosis. Therefore, it is important to prevent, diagnose, and treat the senile disease at an early stage through a bone density test. Bone density is measured by dual energy X-ray absorption (DXA). In this study, while using DXA, in cases when the measurements for both the lumbar and the femur could not be taken simultaneously, the correlation between both measurements were known, and the measurement of one area was used to make a clinical inference for the value of the other. Measurements were taken using Lunar Prodigy Advance (GE) for 43 participant with clinically significant fractures. Statistical calculations were produced and analysed regarding bone density. In case of T-score, lumbar spine produced a statistical result of $-2.112{\pm}1.836$ and femur neck was $-1.716{\pm}1.565$. In case of Z-score lumbar spine produced a statistical result of $-0.151{\pm}1.513$, and femur neck $-0.026{\pm}1.283$. It is indicated that the pearson correlation coefficient of T-score between lumbar spine and femur neck is high at 0.699, and the pearson correlation coefficient of Z-score is considered relatively high at 0.503. The correlation of bone density between lumbar spine and femur neck is shown to be statistically meaningful in T-score's p-value at 0.000 and Z-score's p-value at 0.001. In conclusion, it seems to have clinical usefulness that we can infer the result of one measurement through that of the other part tested, based on the knowledge of the correlation coefficients between lumbar spine and femur neck.

• International Journal of Concrete Structures and Materials
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• v.9 no.2
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• pp.241-254
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• 2015

A lot of reinforced concrete (RC) structures in Syria went out of service after a few years of construction. This was mainly due to reinforcement corrosion or chemical attack on concrete. The use of blended cements is growing rapidly in the construction industry due to economical, ecological and technical benefits. Syria is relatively rich in scoria. In the study, mortar/concrete specimens were produced with seven types of cement: one plain Portland cement (control) and six blended cements with replacement levels ranging from 10 to 35 %. Rapid chloride penetration test was carried in accordance with ASTM C 1202 after two curing times of 28 and 90 days. The effect on the resistance of concrete against damage caused by corrosion of the embedded steel has been investigated using an accelerated corrosion test by impressing a constant anodic potential. The variation of current with time and time to failure of RC specimens were determined at 28 and 90 days curing. In addition, effects of aggressive acidic environments on mortars were investigated through 100 days of exposure to 5 % $H_2SO_4$, 10 % HCl, 5 % $HNO_3$ and 10 % $CH_3COOH$ solutions. Evaluation of sulfate resistance of mortars was also performed by immersing in 5 % $Na_2SO_4$ solution for 52 weeks. Test results reveal that the resistance to chloride penetration of concrete improves substantially with the increase of replacement level, and the concretes containing scoria based-blended cements, especially CEM II/B-P, exhibited corrosion initiation periods several times longer than the control mix. Further, an increase in scoria addition improves the acid resistance of mortar, especially in the early days of exposure, whereas after a long period of continuous exposure all specimens show the same behavior against the acid attack. According to results of sulfate resistance, CEM II/B-P can be used instead of SRPC in sulfate-bearing environments.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1911-1915
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• 2012

Aim: New technologies for the early detection of pancreatic cancer (PC) are urgently needed. The aim of the present study was to screen for the potential protein biomarkers in serum using proteomic fingerprint technology. Methods: Magnetic beads combined with surface-enhanced laser desorption/ionization (SELDI) TOF MS were used to profile and compare the protein spectra of serum samples from 85 patients with pancreatic cancer, 50 patients with acute-on-chronic pancreatitis and 98 healthy blood donors. Proteomic patterns associated with pancreatic cancer were identified with Biomarker Patterns Software. Results: A total of 37 differential m/z peaks were identified that were related to PC (P < 0.01). A tree model of biomarkers was constructed with the software based on the three biomarkers (7762 Da, 8560 Da, 11654 Da), this showing excellent separation between pancreatic cancer and non-cancer., with a sensitivity of 93.3% and a specificity of 95.6%. Blind test data showed a sensitivity of 88% and a specificity of 91.4%. Conclusions: The results suggested that serum biomarkers for pancreatic cancer can be detected using SELDI-TOF-MS combined with magnetic beads. Application of combined biomarkers may provide a powerful and reliable diagnostic method for pancreatic cancer with a high sensitivity and specificity.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1125-1125
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• 2001

Micro-scale test methods are producing small-sample size where the conventional physical and chemical tests can not be used (high standard deviation, uncertain sampling conditions, low repeatability). Different small-scale test methods were developed recently for determination of physico-chemical, functional, rheological properties of wheat or wheat dough using miniaturized instruments with sophisticated sample preparation/handling and mechanics (RVA, 2 g mixograph, micro-Z-arm mixer, small-scale noodle maker, micro-baking method etc.). The small-scale methodologies can be used as basic research tools or as technology supported measurements and can be also essential in the early selection for quality traits in breeding programs. The milling as a sample preparation step is essential procedure providing good quality flour or semolina samples from small amount of grain (5-10 g) in a reproducible and reliable way. The aim of present study was to use NIR as quality control tool, and to evaluate the recently developed and manufactured micro-scale lab mill (FQC-2000) produced by Inter-Labor Co. Ltd., Hungary. The milling characteristics of the new instrument were compared to other laboratory mills and the effects of milling action on the chemical composition of fractions were analysed. The fractions were tested with both chemical and near infrared spectroscopic methods. The micro-scale milling resulted significantly different yields, particle size distributions and different fractions from compositional point of view. The near infrared spectra were sensitive enough to distinguish the fractions obtained by different milling procedures. Quantitative NIR calibration equations were developed and tested in order to measure the chemical composition of characteristic milling fractions. Special qualification procedure the PQS (Polar Qualification System) method was used for detecting the differences between fractions obtained by macro and micro-milling procedures. The results and the limitations of PQS method in this application will be discussed.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3295-3300
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• 2016

Background: Different types of cancer exhibit abnormalities in cell cycle regulators. The murine double minute-2(MDM2) cell cycle regulator is a proto-oncogene that negatively regulates the P53 tumour suppressor gene. Surface epithelial tumours constitute approximately two thirds of ovarian neoplasms. Each histologic type can be classified as benign, borderline and malignant. This study aimed to examine immunohistochemical expression of the MDM2 protein in ovarian serous and mucinous epithelial tumours (benign, borderline and malignant). Materials and Methods: This study included forty five ovarian tumours, subdivided into fifteen cystadenomas (5 serous and 10 mucinous), fifteen borderline tumours (11 serous and 4 mucinous) and fifteen cystadenocarcinomas (9 serous and 6 mucinous). Paraffin sections were stained with haematoxylin and eosin for histopathologic study, and with mouse monoclonal anti-MDM2 antibody for immunohistochemistry. Results: MDM2 positivity was detected in 28.9% of the studied ovarian tumours. All benign tumours were negative and positivity was significantly higher in malignant than borderline tumours (P value of chi-square test =0.000). Significantly, all MDM2 positive mucinous tumours were malignant with no positive mucinous borderline tumours. Malignant tumours showed positive MDM2 expression in 83.3% of mucinous type and in 55.6% of serous type. Borderline serous tumours showed negative MDM2 in 72.7% of cases (P value of Z test =0.04). Conclusions: Alterations in the expression of the cell cycle regulator (MDM2) occur early in the process of tumourigenesis in serous and mucinous ovarian tumours. We suggest that MDM2 may be used in those tumours as a marker for risk stratification and identification of cases with cancer development and progression. We recommend further studies on MDM2 immunohistochemistry, in conjunction with adjuvant methods as DNA ploidy and FISH gene amplification, focusing on the mucinous tumours and differentiating between the three tumour categories, benign, borderline and malignant.