• 제목/요약/키워드: early age damage

검색결과 125건 처리시간 0.157초

소아 중복 요관의 임상적 고찰 (Clinical Manifestations of Ureteral Duplication in Children)

  • 한정우;황대환;박지민;한상원;이재승
    • Childhood Kidney Diseases
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    • 제7권2호
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    • pp.189-196
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    • 2003
  • 목적 : 중복 요관은 부검상 전인구의 0.9%에서 발견되는 비교적 흔한 비뇨기계 기형이다. 과거에는 발열, 복통, 혈뇨 등을 단서로 하여 발견되었으나, 최근에는 산전초음파에 의하여 조기 진단되고 있다. 저자들은 최근 5년간 본원에서 진단된 환아들의 임상 양상 및 산전초음파에 의한 조기 진단의 유용성에 대해 고찰하였다. 방법 : 1998년부터 2003년 7월까지 본원에 입원하여 진단된 18세 미만의 55례의 중복 요관 환아들을 대상으로 후향적 고찰을 시행하였다. 결과 : 진단 당시 평균 연령은 2.2세였고, 추적 기간의 평균은 14개월이었으며, 남녀비는 1:2.7이었다. 완전 중복 요관은 49례(89%)였다. 발열을 주소로 내원한 경우는 15례(27%)였고, 산전 진찰로 진단된 경우는 26례(47%)였다. 방광요관역류가 동반된 경우는 14례(28%)였고, 수신증은43례(88%)에서 동반되었다. 산전 진찰을 통해 진단된 군과 생후에 진단된 군의 비교시, DMSA 신주사상 결손의 비율은 각각 70.8%와 67.7%였으며, 환측 신장의 동위원소 섭취율은 각각 48.2%와 45.5%로 두 군간에 통계학적인 차이는 없었다. 결론 : 과거와 달리 최근 5년간 산전초음파로 중복 요관이 진단되는 비율은 47%로 증가하고 있으며, 이에 따라 진단시 연령이 낮아져(2.2세) 경과 추적이 조기에 시작될 수 있었다. 그 외의 임상적인 양상은 과거와 유사하였다. 산전초음파로 진단된 경우와 생후에 진단된 경우를 비교할 때, 두 군간에 신손상의 차이에 대한 통계적학적 유의성은 발견하지 못하였다. 산전 초음파가 조기 진단과 이에 따른 추적 관찰을 통해 치료시기를 적절히 결정하는 데에 도움이 될 것인지 알아보기 위하여 향후 광범위한 다기관 연구가 필요하다.

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제천 의림지 소나무 연륜생장 쇠퇴도 분석을 통한 고사 연도 및 원인규명 연구 (Examination of Death Years and Causes by the Analysis of Growth Decline in Tree Rings of Pinus densiflora from the Euilimji Lake Park in Jecheon, Korea)

  • 서정욱;박원규
    • 한국환경복원기술학회지
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    • 제14권2호
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    • pp.1-10
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    • 2011
  • Six pine trees (Pinus densiflora S. et Z.) at the Euilimji Lake Park in Jecheon were collected to investigate tree ages, growth decline pattern and the years of death. Tree-ring measurement was carried out using the Lintab with a resolution of 0.01mm. Tree age were 80-176 years. Cross-dating between the tree-ring series of each tree and the local chronology from Worak Mountain resulted that four and two trees died in 1998 and 1999, respectively. Three dead trees had only formed earlywood in the outermost tree ring and the others had incomplete latewood. Therefore, it was proven that the former trees died between spring and early summer, whereas the later ones died during late summer and/or autumn. The simultaneous deaths of trees suggest the insect damage and/or drought may be the crucial reason of the death, but frequent reaction woods, which were formed by leaning stem, and scars formed by physical damage may also contribute to the death.

Minimum thickness of flat plates considering construction load effect

  • Hwang, Hyeon-Jong;Ma, Gao;Kim, Chang-Soo
    • Structural Engineering and Mechanics
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    • 제69권1호
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    • pp.1-10
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    • 2019
  • In the construction of flat plate slabs, which are widely used for tall buildings but have relatively low flexural stiffness, serviceability problems such as excessive deflections and cracks are of great concern. To prevent excessive deflections at service load levels, current design codes require the minimum slab thickness, but the requirement could be unconservative because it is independent on loading and elastic modulus of concrete, both of which have significant effects on slab deflections. In the present study, to investigate the effects of the construction load of shored slabs, reduced flexural stiffness and moment distribution of early-age slabs, and creep and shrinkage of concrete on immediate and time-dependent deflections, numerical analysis was performed using the previously developed numerical models. A parametric study was performed for various design and construction conditions of practical ranges, and a new minimum permissible thickness of flat plate slabs was proposed satisfying the serviceability requirement for deflection. The proposed minimum slab thickness was compared with current design code provisions and numerical analysis results, and it agreed well with the numerical analysis results.

초기동해를 받은 고로슬래그 다량 혼입 콘크리트의 강도발현 및 동결융해 저항성 (Strength Development and Freeze-Thaw Resistance of Concrete Incorporating High Volume Blast-Furnace Slag Subjected to Initial Frost Damage)

  • 고경택;류금성
    • 한국건설순환자원학회논문집
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    • 제6권3호
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    • pp.79-87
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    • 2011
  • 고로슬래그를 다량으로 혼입한 콘크리트를 동절기에 시공할 경우에는 배합에 따라서 응결과 경화가 현저히 지연되어 초기동해를 받을 위험성이 높다. 따라서 이 연구에서는 동절기에 고로슬래그를 다량으로 혼입한 콘크리트가 재령 초기에 동결을 받은 경우를 상정하여 초기동해가 콘크리트의 압축강도와 동결융해 저항성에 미치는 영향을 검토하였다. 그 결과, 고로슬래그를 다량으로 혼입한 콘크리트는 초기동해를 받음으로써 압축강도와 동결융해 저항성 모두가 현저히 저하되고, 고로슬래그를 혼입하지 않은 일반콘크리트에 비해서 특히 동결융해 저항성이 크게 저하되는 것으로 나타났다.

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참다래를 가해하는 해충과 우점종인 열매꼭지나방의 가해특성 (Investigation of Insect Pests and Injury Characteristics of Stathmopoda auriferella (Walker) on Kiwi Fruit Tree)

  • 박종대;박인진;한규평
    • 한국응용곤충학회지
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    • 제33권3호
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    • pp.148-152
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    • 1994
  • 1991~1993년에 참다래 집단 재배지역인 전남 남부해안지방을 중심으로 참다래를 가해하는 해충과 우점종인 열매꼭지나방의 가해특성에 관하여 연구한 결과 해충은 총 12과 13종이 조사되었으며 그중 열매꼭지나방과 뽕나무깍지벌레가 우점종이었다. 열매꼭지나방 의 태별크기는 난이 0.12mm, 종령유충이 9.8mm, 용이 5.9mm 그리고 성충의 날개편 길이는 12.3mm이었다. 열매꼭지나방에 의한 피해과율은 평균 45.9%이었으며 지역에 따라 큰 차이를 인정할 수 없었다. 성충은 연 2회발생하며 1회는 5월하순~7월중순 , 2회는 8월중순~9월상순으로 최성기는 각각 6월상중순, 8월하순이었다. 시기별 유충과 용의 비율은 7월상순에서 100:0이었다. 중순은 96.1:3.9, 하순은 64.9:35.1 이었고 8월 상순에는 19.8:80.2, 중순은 0:100이었다. 또한 피해과는 7월상순에 4.6%로 처음 발견되었으며 7월중순 이후에는 40%이상으로서 이 시기의 피해가 당년의 피해정도를 결정하였고 가해하는 부위는 과정부가 70%, 과경부가 11.1%이었으며 품종별로는 국내 주 지배품종인 헤이워드 32.2%, 몬티 22.2% 향록 13.9%, 아보트 9.3%. 브로노 6.0% 이었다.

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Development of Efficient Curing Sheet for Thermal Insulation Curing of Concrete in Cold Weather

  • Han, Cheon-Goo;Son, Myung-Sik;Choi, Hyun-Kyu
    • 한국건축시공학회지
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    • 제12권3호
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    • pp.291-298
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    • 2012
  • For cold weather concreting, frost damage at early age is generated in the concrete, and problems such as delaying of setting and hardening and lowering of strength manifestation emerge due to the low outside air temperature at the early stage of pouring, making the selection of an effective curing method critically important. Unfortunately, the tent sheet currently used as the curing film for heating insulation at work sites, not only has the problems of inferior permeability and extremely deteriorated airtightness, but a phenomenon of continuous fracturing is also generated along the direction of fabric of the material itself, presenting difficult circumstances for maintaining adequate curing temperature. The aim of this study was to develop an improved bubble sheet type curing film for heating insulation of cold weather concrete by combining mesh-tarpaulin, which has excellent tension properties, with bubble sheet, which offers superior insulation performance. The analysis showed that the improved curing film in which BBS1 is stacked to MT was a suitable replacement for curing films currently in use, as it has better permeability, tension property, and insulation performance than the T type film used at work sites today.

환원슬래그를 사용한 모르타르의 저온에서의 초기동해 방지에 관한 기초적 실험 (A Fundamental Experiment on Preventing Frost Damage at Early Age of Mortar in Low Temperature using Reduction Slag)

  • 민태범;문영범;김형철;최현국;김재영;이한승
    • 한국건축시공학회지
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    • 제16권1호
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    • pp.1-7
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    • 2016
  • 본 연구에서는 $-5^{\circ}C$이하에서도 가열 양생이 없이 수화 반응시 수화열이 높게 발생되는 환원슬래그를 시멘트 분체와 치환사용 하여 영하의 온도에서도 콘크리트의 자체 발열로 인해 압축강도를 재령 3일 이내 5MPa를 발현시켜 초기동해를 방지시키는 것이 최종 연구의 목적이며 이에 대하여 환원슬래그의 물리적 특성 평가와 열적 특성 평가를 실시한 결과 환원슬래그는 높은 수화열을 발생시키기 때문에 저온에서도 압축강도 발현이 우수함을 알 수 있었다. 이는 환원 슬래그의 성분 중 $C_{12}A_7$$C_3A$에 의해 수화열이 높게 발생됨 저온에서도 압축강도가 발현되는 것으로 나타났다. 하지만 환원슬래그 단독 치환하였을 경우 $SO_3$함량 부족으로 급결이 발생하는 것을 알 수 있었다. 급결을 방지하기 위해서는 석고의 사용이 필수적으로 사용되어야 한다. 따라서 본 연구 결과 환원슬래그와 석고를 3성분계로 사용하였을 경우 저온에서도 재령 3일에서 5MPa 압축강도를 나타나는 것으로 보아 저온에서도 콘크리트의 초기동해를 방지할 수 있을 것으로 판단된다.

Juvenile idiopathic arthritis: Diagnosis and differential diagnosis

  • Kim, Ki-Hwan;Kim, Dong-Soo
    • Clinical and Experimental Pediatrics
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    • 제53권11호
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    • pp.931-935
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    • 2010
  • Juvenile idiopathic arthritis (JIA) is comprised of a heterogeneous group of several disease subtypes that are characterized by the onset of arthritis before the age of 16 years and has symptoms lasting at least 6 weeks. The previous classification of JIA included seven different categories, whereas its current classification was compiled by the International League of the Association for Rheumatology, and replaced the previous terms of "juvenile chronic arthritis" and "juvenile rheumatoid arthritis," which were used in Europe or North America, respectively, with the single nomenclature of JIA. As mentioned above, JIA is defined as arthritis of unknown etiology that manifests itself before the age of 16 years and persists for at least 6 weeks, while excluding other known conditions. The clinical symptoms of JIA can be quite variable. Several symptoms that are characteristic of arthritis are not necessarily diagnostic of JIA and may have multiple etiologies that can be differentiated with careful examination of patient history. The disease may develop over days or sometimes weeks, thereby making the diagnosis difficult at the time of presentation. To make a clinical diagnosis of JIA, the first step is to exclude arthritis with known etiologies. Of note, late treatment due to excessive delay of diagnosis can cause severe damage to joints and other organs and impair skeletal maturation. Therefore, early detection of JIA is critical to ensure prompt treatment and to prevent long-term complications including the likelihood of disability in childhood.

A Case of Secondary FSGS due to Chronic Chloride Diarrhea

  • Kim, Byung Kwan;Lee, Hyun Soon;Yim, Hyung Eun;Cheong, Hae Il;Yoo, Kee Hwan
    • Childhood Kidney Diseases
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    • 제20권2호
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    • pp.83-87
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    • 2016
  • Congenital chloride diarrhea (CLD) is a rare autosomal recessive disease that is difficult to diagnose. CLD requires early treatment to correct electrolyte imbalance and alkalosis and to prevent severe dehydration. Renal injury is clearly associated with defective electrolyte balance induced by CLD, particularly during the first months or years of life. A 7-year-old boy was diagnosed with CLD following detection of a homozygous mutation (c.2063-1G>T) in SLC26A3 at 6 months of age. During treatment with electrolyte supplements, mild proteinuria was detected at 8 months of age, and is still present. Renal biopsy showed the presence of focal renal dysplasia, with metaplastic cartilage and mononuclear cell infiltration, calcification, and fibrosis in the interstitium. Up to two-thirds of the glomeruli exhibited global obsolescence, mostly aggregated in the dysplastic area. In nondysplastic areas, the glomeruli were markedly increased in size and severely hypercellular, with increased mesangial matrix, and displayed segmental sclerosis. The marked glomerular hypertrophy with focal segmental glomerulosclerosis suggested a compensatory reaction to the severe nephron loss or glomerular obsolescence associated with renal dysplasia, with superimposed by CLD aggravating the tubulointerstitial damage.

Visualization of Phytophthora palmivora Infection in Oil Palm Leaflets with Fluorescent Proteins and Cell Viability Markers

  • Ochoa, Juan C.;Herrera, Mariana;Navia, Monica;Romero, Hernan Mauricio
    • The Plant Pathology Journal
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    • 제35권1호
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    • pp.19-31
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    • 2019
  • Bud rot (BR) is the most devastating disease affecting oil palm (Elaeis guineensis) crops in Colombia. Its causal agent, Phytophthora palmivora, initiates the infection in immature oil palm leaflets producing necrotic lesions, followed by colonization of opportunistic necrotrophs, which increases disease damage. To improve the characterization of the disease, we transformed P. palmivora using Agrobacterium tumefaciens-mediated transformation (ATMT) to include the fluorescent proteins CFP-SKL (peroxisomal localization), eGFP and mRFP1 (cytoplasmic localization). The stability of some transformants was confirmed by Southern blot analysis and single zoospore cultures; additionally, virulence and in vitro growth were compared to the wild-type isolate to select transformants with the greatest resemblance to the WT isolate. GFP-tagged P. palmivora was useful to identify all of the infective structures that are commonly formed by hemibiotrophic oomycetes, including apoplastic colonization and haustorium formation. Finally, we detected cell death responses associated with immature oil palm tissues that showed reduced susceptibility to P. palmivora infection, indicating that these tissues could exhibit age-related resistance. The aim of this research is to improve the characterization of the initial disease stages and generate cell biology tools that may be useful for developing methodologies for early identification of oil palm materials resistant or susceptible to BR.