• Asia pacific journal of information systems
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• v.20 no.2
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• pp.1-21
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• 2010

e-Government is an innovative phenomenon around the globe for refurbishing public administration. Research to date, however, has been deficient in empirical studies of the factors that emerge out of the interplay of structure and human interactions responsible for successful implementation of e-Government projects. From the perspective of structuration theory, this study examines and explains the impact of this interplay in the implementation of an e-Government system, eSeva for local administration at one of the Indian state, The results suggest that the success of implementation of e-Government projects can be conceptualized as the outcome of persisting constructive interrelationships among the human, programmatic and institutional elements of e-Government and the critical learning and adaptation as a result of efforts at the structuration level.

• Environmental Analysis Health and Toxicology
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• v.22 no.2 s.57
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• pp.137-145
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• 2007

The effect of cadmium chloride $(CdCl_2)$ on the expression of E-cadherin was examined in bEnd.3 mouse brain endothelial cells. $CdCl_2$ induced $PGE_2$ release, which were blocked by non-steroidal antinflamatory drugs (NSAIDs) such as indomethacin and NS398 indicating the expression of COX-2 might contribute to $PGE_2$ production. $CdCl_2$ decreased the expression of E-cadherin, but not VE-cadherin at levels of mRNA and protein. Reduced expression level of E-cadherin was restored by NSAIDs, which was reversed by the addition of $PGE_2$. $CdC_2$-induced decrease of E-cadherin level was also recovered by antioxidants including N-acetylcyteine (NAC) and trolox. Together with previous report which showed $CdCl_2$ induced COX-2 expression in a cellular oxidative stress dependent manner, these data suggest that $CdCl_2$ decreases E-cadherin expression through induction of cellular oxidative stress and in turn COX-2 expression in brain endothelial cells.

• Journal of Microbiology and Biotechnology
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• v.32 no.6
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• pp.800-807
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• 2022

Four aprE genes encoding alkaline serine proteases from B. subtilis strains were used as template genes for family gene shuffling. Shuffled genes obtained by DNase I digestion followed by consecutive primerless and regular PCR reactions were ligated with pHY300PLK, an E. coli-Bacillus shuttle vector. The ligation mixture was introduced into B. subtilis WB600 and one transformant (FSM4) showed higher fibrinolytic activity. DNA sequencing confirmed that the shuffled gene (aprEFSM4) consisted of DNA mostly originated from either aprEJS2 or aprE176 in addition to some DNA from either aprE3-5 or aprESJ4. Mature AprEFSM4 (275 amino acids) was different from mature AprEJS2 in 4 amino acids and mature AprE176 in 2 amino acids. aprEFSM4 was overexpressed in E. coli BL21 (DE3) by using pET26b(+) and recombinant AprEFSM4 was purified. The optimal temperature and pH of AprEFSM4 were similar to those of parental enzymes. However, AprEFM4 showed better thermostability and fibrinogen hydrolytic activity than the parental enzymes. The results indicated that DNA shuffling could be used to improve fibrinolytic enzymes from Bacillus sp. for industrial applications.

• Proceedings of the Korean Society of Computer Information Conference
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• 2014.01a
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• pp.211-214
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• 2014

최근 E-Service의 기술 촉진이나 적용 범위는 점차 확대되어가고 있으나, 이에 반해 E-Service의 이론과 실행은 여전히 초기 단계이고, E-Service상의 서비스나 서비스 경험에 대한 정의가 부재인 것으로 확인되고 있다. 따라서 본 논문에서는 전통적 서비스와 E-Service의 차이점을 도출하여 E-Service만의 특화점을 학문적으로 확인하여 보고자 한다. 이를 위하여 E-Service의 정의를 우선 설명하고, 전통적인 서비스의 주요 특성 5가지를 활용하여 E-Service와의 특성을 비교한 후, 5가지 특성에서 각각 전통적인 서비스와 E-Service간에 어떤 차이점이 있는지를 밝혀보고자 한다. 마지막으로 E-Service의 가장 큰 특징인 기술과 정보의 만남을 통해 가치의 창조가 포함되는 점을 추가하여 E-Service가 기존 상품이나 오프라인 서비스에 대한 보완재나 대체제가 아닌 E-Service 만의 고유 핵심 가치를 보유하고 있다는 점을 이용하여 명백한 E-Service만의 우위 요소를 정의한 후 학문적으로 명확한 차이점을 밝혀내 보고자 한다.

• The Journal of Advanced Prosthodontics
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• v.8 no.6
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• pp.479-488
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• 2016

PURPOSE. The aim of this study was to test the modulus of elasticity (E) across the interfaces of yttria stabilized zirconia (YTZP) / veneer multilayers using nanoindentation. MATERIALS AND METHODS. YTZP core material (KaVo-Everest, Germany) specimens were either coated with a liner (IPS e.max ZirLiner, Ivoclar-Vivadent) (Type-1) or left as-sintered (Type-2) and subsequently veneered with a pressable glass-ceramic (IPS e.max ZirPress, Ivoclar-Vivadent). A $5{\mu}m$ (nominal tip diameter) spherical indenter was used with a UMIS CSIRO 2000 (ASI, Canberra, Australia) nanoindenter system to test E across the exposed and polished interfaces of both specimen types. The multiple point load - partial unload method was used for E determination. All materials used were characterized using Scanning Electron Microscopy (SEM) and X - ray powder diffraction (XRD). E mappings of the areas tested were produced from the nanoindentation data. RESULTS. A significantly (P<.05) lower E value between Type-1 and Type-2 specimens at a distance of $40{\mu}m$ in the veneer material was associated with the liner. XRD and SEM characterization of the zirconia sample showed a fine grained bulk tetragonal phase. IPS e-max ZirPress and IPS e-max ZirLiner materials were characterized as amorphous. CONCLUSION. The liner between the YTZP core and the heat pressed veneer may act as a weak link in this dental multilayer due to its significantly (P<.05) lower E. The present study has shown nanoindentation using spherical indentation and the multiple point load - partial unload method to be reliable predictors of E and useful evaluation tools for layered dental ceramic interfaces.

• Childhood Kidney Diseases
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• v.23 no.1
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• pp.29-35
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• 2019

Purpose: We aimed to determine characteristics of host, causative organisms, and antibiotic susceptibility of bacteria in pediatric patients with UTI living in metropolitan area of Korea. Methods: Retrospective investigation was done for the causative organisms of UTI in 683 pediatric cases treated at Ajou University Hospital from 2012 to 2017. Patients were classified into Escherichia coli and non-E. coli group, where E. coli group was subdivided into ESBL(+) and ESBL(-) groups based on whether the bacteria could produce extended spectrum beta-lactamase (ESBL). Antibiotic susceptibility of the causative organism was also determined. Results: A total of 683 UTIs occurred in 550 patients, of which 463 (67.8%) were first-time infection and 87 (32.2%) were recurrent ones (2-7 recurrences, 2.52 average), and 64.9% were male and 35.1% were female. The most common causative organism was E. coli (77.2%) and ESBL(+) E. coli was found in 126 cases. The susceptibility of E. coli to 3rd or 4th generation cephalosporin was relatively higher than that to ampicillin or amoxicillin/clavulanic acid. ESBL(+) E. coli showed higher resistance rate to 3rd or 4th generation cephalosporin than ESBL(-) E. coli. Conclusion: New treatment guideline should be considered due to the incidence of ESBL(+) E. coli increased up to one quarter of UTI cases.

• Cartoon and Animation Studies
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• s.49
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• pp.425-464
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• 2017

The Knowledge of the Channel (e) is often used as educational materials; it delivers very short but compelling message of strong or interesting timeliness. However, as the media environment changes, expectations and demands for The Knowledge The Knowledge of the Channel (e) is used in school education and what should be improved upon to increase utilization of educational resources. We surveyed 361 elementary, middle and high school teachers and analyzed the frequency of using, approach and learning activities of The Knowledge of the Channel (e) in school education. We also analyzed difficulties in using it in the school and what improvements should be made. Result show that the frequency of using The Knowledge of the Channel (e) in school is highest in elementary schools, followed by middle school, and then high school. Teachers strongly consider curricular relevance when selecting broadcasting contents for education, and among programs of EBS(Educational Broadcasting System), most frequently use The Knowledge of the Channel (e). The The Knowledge of the Channel (e) is mainly used as an incentive for increasing motivation. When examined by elementary school curriculum, this material is highly utilized in subjects with content such as society, morality, and science, or with approaches that require various perspectives. However, it is difficult for teachers to find materials directly related to their classes, and since other media content similar to The Knowledge of the Channel (e) is abundant, the utilization of The Knowledge of the Channel (e) is decreasing. To improve this, The Knowledge of the Channel (e) needs to improve its platform and transformed the type of The Knowledge of the Channel (e) content being provided on social media.

• Proceedings of the Korea Information Processing Society Conference
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• 2002.11c
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• pp.2191-2194
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• 2002

전자상거래 또는 e-Business에 대한 정부 등 각계 기관과 기업들의 관심이 매우 고조되고 있다. 현실적으로 e-Business를 도입하려는 일반 중소기업들은 매우 많은 어려움에 직면하고 있다. 수많은 솔루션과 다양한 방법론 그리고 경영전략 등을 체계적으로 수립해야하고 다양한 정책을 활용하는 과정을 필요로 하기 때문이다. 본 연구는 중소기업을 위한 전자상거래 또는 e-Business 환경구축에 대한 eSCM과 eCRM의 핵심기능을 포함한 eSCS(eSCM+eCRM)통합시스템 모델과 설계에 관하여 다루고 있다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.07a
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• pp.155-158
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• 2023

최근 몇 년간 e스포츠 산업은 전 세계적으로 꾸준히 성장하고 있다. 특히 모바일게임은 PC나 콘솔 게임에 비해 낮은 비용으로 쉽게 접근할 수 있어 모바일 e스포츠 산업 규모 또한 점진적인 성장을 보이고 있다. 하지만 국내 모바일 e스포츠 산업은 해외 모바일 e스포츠 산업과 비교했을 때 시장의 규모에서 큰 차이를 보였고, 국내 PC e스포츠 산업과 비교해 보아도 상대적으로 시장 규모가 작아 국내에서는 모바일 e스포츠 산업이 비주류로서 소비되는 모습을 확인할 수 있었다. 본 논문에서는 다른 국가의 모바일 e스포츠 흥행 요인 등을 분석하여 국내 모바일 e스포츠 산업 발전 방안을 제시하고, 국내 e스포츠 산업의 새로운 수익 모델로 모바일 e스포츠를 제안하고자 한다.

• Journal of the Korean Society of Earth Science Education
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• v.2 no.1
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• pp.23-32
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• 2009

e-PBL based on constructivism adopted PBL(Problem Based Learning) and WBI(Web Based Learning), and it becomes the advanced model of instruction to be achieved PBL on-line. In this thesis, I applied e-PBL to 'the changing weather' part in the high school earth science I, compared to the lecture centered instruction, and analyzed how it affected on. On the basis of these, this study predicts the applicability on the cooperative learning and self-directed learning in the high school and suggests the improving of the teaching-learning with the results. The following shows the conclusion with as the central result of research. Firstly, the instruction applied e-PBL proved more effective academic achievement than the lecture centered instruction. Secondly, the instruction applied e-PBL proved more effective on the improving self-directed learning ability. Thirdly, the instruction applied e-PBL proved more effective self-efficacy than the lecture centered instruction.