• 한국환경교육학회지:환경교육
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• 제8권1호
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• pp.122-137
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• 1995

The Environmental Education(E.E.) is very important field in Elementary and Secondary School. And the first important problem of E.E. in school is no special teacher. This thesis is a study on the system of E.E. major in the graduate school of education. 1. The aims of E.E. major are training of E.E. teacher and developing research of E.E. 2. The curriculum of E.E. major is consisted of E.E. theory and E.E. content. 3. The student of E.E. major is admited a university graduate of social science and natural science department. 4. The professor of E.E. major is organized a specialist of E.E.

• 대한한의학회지
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• 제24권4호
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• pp.113-119
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• 2003

The association between apolipoprotein E (apo E) gene polymorphism and ischemic cerebrovascular disease (ICVD) has been controversial. These controversies may be due to inaccurate classification of patients and ethnic differences. We investigated the association between apo E genotypes and ICVD patients by case-control study in a Korean population. The association between apo E polymorphism and ICVD was examined in 121 patients with ICVD and 132 controls without ICVD. The E3/E4 phenotype was more frequent in control subjects (23.8％) than in patients (13.0％) (p<0.05). The E2/E3 phenotype was more frequent in patients (14.8％) than in control subjects (10.8％), but the difference was not statistically significant (p>0.05). These results suggest that the E4 allele may be a protective factor against early vascular morbidity, and the E2 allele may be a risk factor for cerebrovascular morbidity.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2011년도 춘계학술대회
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• pp.399-402
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• 2011

빠르게 변화하는 디지털 경제시대에서 e-business 기술과 인력의 확보는 국가 e-business 산업 확산과 기업 발전에 매우 중요한 요소이다. 시대의 변화에 따라 e-business 분야의 인력 양성은 이론과 기술 중심의 대학과 대학원 중심체제에서 실무를 중심으로 한 고등학교 과정에의 인력양성에 대한 필요성과 연구성이 필요하다. 본 논문에서는 최근 변화되고 있는 특성화 고등학교의 e-business 정책과 더불어 e-business 분야의 특성화 체제의 변화를 위해 필요한 직무와 요구되는 스킬을 분석하여 특성화학과와 교과에 대한 기본 연구 자료를 제공한다. 또한 일반 고등학교나, 특성화 고등학교에서 e-business 특성화 고등학교 체제로 변화 할 수 있는 로드맵을 제시하여 국가 사회적인 e-business 기술과 인력의 확보를 위해 노력하고자 한다.

• Journal of Korean Neurosurgical Society
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• 제29권6호
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• pp.725-730
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• 2000

Purpose : The subcellular localization of E1B-19k has been known cytosol or nuclear membrane by immunohistochemical staining and could dimerize with Bax to regulate cell death also known by the in-vitro immunoprecipitation. We planed to confirm this dimerization of E1B-19k with Bax in vivo in Cos-7 cells by using green fluorescent protein. Material and Method : We cloned E1B-19k and Bax into C3-EGFP. C3-EGFP-E1B-19k, C3-EGFP-Bax, and C3-EGFP-E1B-19k and pcDNA3-Bax were transfected into Cos-7 cells. We explored location of E1B-19k and Bax, and confirmed its dimerization with Bax in transfected living healthy Cos-7 cells by following green fluorescent protein of E1B-19k on the confocal microscope. Results : E1B-19k was located diffusely in cytoplasm and in nucleus but not in mitochondria. It prevented cell death from the apoptosis by staurosporine but its location was not changed. GFP-E1B-19k is not changed its intracellular location with Bax even with staurosporine. Conclusion : These results support that E1B-19k does not localize in mitochondria nor dimerize with Bax even with staurosporine. We could anticipate E1B-19k prevent cell death via the other dimerizing partner or pathways.

• 한국산학기술학회논문지
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• 제6권1호
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• pp.64-71
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• 2005

본 논문에서는 유비쿼터스(Ubiquitous) 혁명이 미래학교를 어떻게 변화시킬 것인가 예측해 보며, 유비쿼터스 컴퓨팅과 유비쿼터스 네트워크기술을 중심으로 지식사회에서의 e-learning 과 ICT (Information Communication Technology) 활용한 학습 연구를 수행하였다. 또한 e-school 의 모형과 협동학습을 기반으로 하는 블렌디드 러닝(Blended-Loaming) 활용 교수-학습 과정 안을 제안한다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제16권2호
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• pp.123-126
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• 2013

$M\acute{e}n\acute{e}$trier's disease is a rare protein-losing gastropathy characterized by hypertrophic gastric fold, foveolar hyperplasia, and hypoproteinemia with resulting peripheral edema. It is clinically evident as nonspecific gastrointestinal symptoms, including abdominal discomfort, nausea and vomiting, abdominal pain, weight loss, diarrhea, and edema. Pediatric $M\acute{e}n\acute{e}$trier's disease usually has an insidious onset and progressive, chronic clinical course and it spontaneously resolves in weeks or months. The pathogenesis of $M\acute{e}n\acute{e}$trier's disease is not clearly understood. $M\acute{e}n\acute{e}$trier's disease is thought to be associated with some gastric infections. But the cause of $M\acute{e}n\acute{e}$trier's disease is unknown, an association with cytomegalovirus (CMV) and Helicobacter pylori has been suggested. In Korea, We present the first a case of pediatric $M\acute{e}n\acute{e}$trier's disease with positive evidence of CMV and H. pylori.

• Journal of Microbiology
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• 제44권5호
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• pp.537-547
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• 2006

This study was designed to determine whether or not Vibrio vulnificus metalloprotease VvpE can promote iron uptake via the proteolytic cleavage of human hemoglobin. We found that V. vulnificus utilized hemoglobin as an iron source more efficiently via the vulnibactin-mediated iron-uptake system than via the HupA-mediated iron-uptake system and, of the proteases produced by V. vulnificus, VvpE was found to be the only protease capable of destroying hemoglobin. However, VvpE expression, on both the transcriptional and protein levels, was suppressed in iron-limited media. However, vvpE transcription, but not extracellular VvpE production, was reactivated by the addition of hemoglobin or inorganic iron into iron-limited media. Moreover, vvpE transcription began only in the late growth phase when V. vulnificus had already consumed most of the iron for growth. In addition, neither vvpE mutation nor in trans vvpE complementation affected the ability of V. vulnificus to acquire iron or to grow in iron-limited media or in cirrhotic ascites containing hemoglobin. Hemoglobin added into iron-limited media was not destroyed, but gradually formed an insoluble aggregate during culture; this aggregation of hemoglobin occurred regardless of vvpE mutation or complementation. These results indicate that VvpE is not required for efficient iron uptake from hemoglobin. On the contrary, hemoglobin or iron is required for efficient vvpE transcription. In addition, a discrepancy exists between vvpE transcription and extracellular VvpE production in iron-limited media containing inorganic iron or hemoglobin, which suggests that additional unknown posttranscriptional events may be involved in the extracellular production of VvpE.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5715-5719
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• 2012

The relation between cyclooxygenase enzymes and E-cadherin, along with the roles of these markers in the prediction of survival in optimally cytoreduced serous ovarian cancer patients was investigated. Individuals who underwent primary staging surgery and achieved optimal cytoreduction (largest residual tumor volume <1 cm) constituted the study population. Specimens of 32 cases were immunohistochemically examined for cyclooxygenase-1, cyclooxygenase-2, and E-cadherin. Two could not be evaluated for E-cadherin and cyclooxygenase-1. Overall, 14/30, 19/30, and 15/32 cases were positive for E-cadherin, cyclooxygenase-1, and cyclooxygenase-2, respectively. The expressions of E-cadherin and cyclooxygenase-2 were inversely correlated (p:0.02). E-cadherin expression was related with favorable survival (p<0.001). The relation between the expression of cyclooxygenase enzymes and poor survival did not reach statistical significance. On multivariate analysis, E-cadherin appeared as an independent prognostic factor for survival. In conclusion, E-cadherin expression is strongly linked with favorable survival. E-cadherin and cyclooxygenase 2 may interact with each other during the carcinogenesis-invasion process. Further studies clarifying the relation between E-cadherin and cyclooxygenase enzymes may lead to new preventive and therapeutic targets in ovarian cancer.

• 인터넷정보학회논문지
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• 제15권5호
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• pp.43-52
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• 2014

본 연구는 한국농수산식품유통공사가 운영하는 공적 B2B e-마켓플레이스인 학교급식전자조달시스템에 참여하고 있는 초중고등학교를 중심으로 참여학교의 거래만족도에 영향을 미칠 수 있는 선행요인에 대한 분석을 목적으로 한다. 사회적 자본, 의사소통, 네트워크내에서의 정보공유, 운영조직의 지원 등을 핵심선행요인으로 설정하고, 학교급식전자조달시스템에 참여하고 있는 초중고등학교를 대상으로 설문조사를 실시하여 연구가설을 검증하였다. 분석결과, 사회적 자본과 지원은 거래만족도에 유의한 영향을 미치고, 지원은 사회적 자본 축적에 긍정적 영향을 미친다는 것을 확인할 수 있었다. 또한 사회적 자본과 지원은 참여구성원간의 의사소통과 네트웍내에서의 정보공유에 의해서 유의한 영향을 받는다는 것을 알 수 있었다. 본 연구의 분석결과는 성공적인 학교급식 조달을 위한 e-마켓플레이스 거래만족도에 영향을 줄 수 있는 선행요인들 사이의 관계를 이해하고 적용하는데 있어 의미 있는 시사점을 제공하리라 본다.

• Parasites, Hosts and Diseases
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• 제45권1호
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• pp.1-9
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• 2007

The endosymbionts of 4 strains of Acanthamoeba(KA/E9, KA/E21, KA/E22, and KA/E23) isolated from the infected corneas of Korean patients were characterized via orcein stain, transmission electron microscopic examination, and 16S rDNA sequence analysis. Double membrane-bound, rod-shaped endosymbionts were distributed randomly throughout both the trophozoites and cysts of each of Acanthamoeba isolates. The endosymbionts of KA/E9, KA/E22, and KA/E23 were surrounded by electron-translucent areas. No lacunae-like structures were observed in the endosymbionts of KA/E21, the bacterial cell walls of which were studded with host ribosomes. Comparative analyses of the 16S rDNA sequences showed that the endosymbionts of KA/E9, KA/E22 and KA/E23 were closely related to Caedibacter caryophilus, whereas the KA/E21 endosymbiont was assigned to the Cytophaga-Flavobacterium-Bacteroides(CFB) phylum. In the 4 strains of Acanthamoeba, the hosts of the endosymbionts were identified as belonging to the Acanthamoeba castellanii complex, which corresponds to the T4 genotype. Acanthamoeba KA/E21 evidenced characteristics almost identical to those of KA/E6, with the exception of the existence of endosymbionts. The discovery of these endosymbionts from Acanthamoeba may prove essential to future studies focusing on interactions between the endosymbionts and the amoebic hosts.