Roles of E-cadherin and Cyclooxygenase Enzymes in Predicting Different Survival Patterns of Optimally Cytoreduced Serous Ovarian Cancer Patients |
Taskin, Salih
(Department of Obstetrics and Gynecology, Ankara University School of Medicine)
Dunder, Ilkkan (Department of Obstetrics and Gynecology, Ankara University School of Medicine) Erol, Ebru (Department of Pathology, Ankara University School of Medicine) Taskin, Elif Aylin (Department of Obstetrics and Gynecology, Ankara University School of Medicine) Kiremitci, Saba (Department of Pathology, Ankara University School of Medicine) Oztuna, Derya (Department of Biostatistics, Ankara University School of Medicine) Sertcelik, Ayse (Department of Pathology, Ankara University School of Medicine) |
1 | Makarla PB, Saboorian MH, Ashfaq R, et al (2005). Promoter hypermethylation profile of ovarian epithelial neoplasms. Clin Cancer Res, 11, 5365-9. DOI ScienceOn |
2 | Menczer J (2009). Cox-2 expression in ovarian malignancies: A review of the clinical aspects. Eur J Obstet Gynecol Reprod Biol, 146, 129-32. DOI |
3 | Moody TW, Switzer C, Santana-Flores W, et al (2010). Dithiolethione modified valproate and diclofenac increase E-cadherin expression and decrease proliferation of nonsmall cell lung cancer cells. Lung Cancer, 68, 154-60. DOI |
4 | Okamoto A, Shirakawa T, Bito T, et al (2008). Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulation of E-cadherin and has antitumor effect on human bladder cancer cells in vitro and in vivo. Urology, 71, 156-60. DOI ScienceOn |
5 | Rathi A, Virmani AK, Schorge JO, et al (2002). Methylation profiles of sporadic ovarian tumors and nonmalignant ovaries from high-risk women. Clin Cancer Res, 8, 3324-31. |
6 | Rao DS, Gui D, Koski ME, et al (2006). An inverse relation between COX-2 and E-cadherin expression correlates with aggressive histologic features in prostate cancer. Appl Immunohistochem Mol Morphol, 14, 375-83. DOI |
7 | Sun WH, Zhu F, Chen GS, et al (2008). Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro. Cancer Lett, 263, 302-11. DOI |
8 | Shim HS, Yoon BS, Cho NH (2009). Prognostic significance of paired epithelial cell adhesion molecule and E-cadherin in ovarian serous carcinoma. Hum Pathol, 40, 693-8. DOI |
9 | Uddin S, Ahmed M, Hussain A, et al (2010). Cyclooxygenase-2 inhibition inhibits PI3K/AKT kinase activity in epithelial ovarian cancer. Int J Cancer, 126, 382-94. DOI |
10 | Voutilainen KA, Anttila MA, Sillanpaa SM, et al (2006). Prognostic significance of E-cadherin-catenin complex in epithelial ovarian cancer. J Clin Pathol, 59, 460-7. DOI |
11 | Yuecheng Y, Hongmei L, Xiaoyan X (2006). Clinical evaluation of E-cadherin expression and its regulation mechanism in epithelial ovarian cancer. Clin Exp Metastasis, 23, 65-74. DOI |
12 | Yoshida J, Horiuchi A, Kikuchi N, et al (2009). Changes in the expression of E-cadherin repressors, Snail, Slug, SIP1, and Twist, in the development and progression of ovarian carcinoma: the important role of Snail in ovarian tumorigenesis and progression. Med Mol Morphol, 42, 82-91. DOI |
13 | Wang Y, Sheng Q, Spillman MA, et al (2012). Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells. Oncogene, 31, 2512-20 DOI |
14 | Zhou Y, Ran J, Tang C, et al (2007). Effect of celecoxib on E-cadherin, VEGF, Microvessel density and apoptosis in gastric cancer. Cancer Biol Ther, 6, 269-75. |
15 | Chi DS, Liao JB, Leon LF, et al (2001). Identification of prognostic factors in advanced epithelial ovarian carcinoma. Gynecol Oncol, 82, 532-7. DOI ScienceOn |
16 | Ali-Fehmi R, Morris RT, Bandyopadhyay S, et al (2005). Expression of cyclooxygenase-2 in advanced stage ovarian serous carcinoma: Correlation with tumor cell proliferation, apoptosis, angiogenesis, and survival. Am J Obstet Gynecol, 192, 819-25. DOI |
17 | Brouxhon S, Kyrkanides S, O'Banion MK, et al (2007). Sequential down-regulation of E-cadherin with squamous cell carcinoma progression: loss of E-cadherin via a prostaglandin E2-EP2 dependent posttranslational mechanism. Cancer Res, 15, 7654-64. |
18 | Blechschmidt K, Sassen S, Schmalfeldt B, et al (2008). The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients. Br J Cancer, 98, 489-95. DOI |
19 | Chang YW, Marlin JW, Chance TW, et al (2006). RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility. Cancer Res, 66. 11700-8. DOI |
20 | Chen Q, Shinohara N, Abe T, et al (2004). Impact of cyclooxygenase-2 gene expression on tumor invasiveness in a human renal cell carcinoma cell line. J Urol, 172, 2153-7. DOI |
21 | Cho EY, Choi Y, Chae SW, et al (2006). Immunohistochemical study of the expression of adhesion molecules in ovarian serous neoplasms. Pathol Int, 56, 62-70. DOI |
22 | Denkert C, Kobel M, Pest S, et al (2002). Expression of cyclooxygenase 2 is an independent prognostic factor in human ovarian carcinoma. Am J Pathol, 160, 893-903. DOI |
23 | Dohadwala M, Yang SC, Luo J, et al (2006). Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in nonsmall cell lung cancer. Cancer Res, 66, 5338-45. DOI |
24 | Erkinheimo TL, Lassus H, Finne P, et al (2004). Elevated cyclooxygenase-2 expression is associated with altered expression of p53 and SMAD4, amplification of HER 2/ neu, and poor outcome in serous ovarian carcinoma. Clin Cancer Res, 10, 538-45. DOI |
25 | Gupta RA, Tejada LV, Tong BJ, et al (2003). Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer. Cancer Res, 63, 906-11. |
26 | Faleiro-Rodrigues C, Macedo-Pinto I, Pereira D, et al (2004). Prognostic value of E-cadherin immunoexpression in patients with primary ovarian carcinomas. Ann Oncol, 15, 1535-42. DOI ScienceOn |
27 | Jin HY, Feng YJ (2005). Inhibitory effects of antisense Snail on invasion and migration of ovarian carcinoma cells. Zhong Hua Fu Chan Ke Za Zhi, 40, 400-3. |
28 | Harris RE, Beebe-Donk J, Doss H, et al (2005). Aspirin, ibuprofen, and other nonsteroidal anti-inflammatory drugs in cancer prevention: a critical review of nonselective COX-2 blockade. Oncol Rep, 13, 559-83. |
29 | Huang KJ, Sui LH (2012). The relevance and role of vascular endothelial growth factor C, matrix metalloproteinase-2 and E-cadherin in epithelial ovarian cancer. Med Oncol, 29, 318-23. DOI |
30 | Imai T, Horiuchi A, Wang C, et al (2003). Hypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cells. Am J Pathol, 163, 1437-47. DOI |
31 | Jang TJ, Jeon KH, Jung KH (2009). Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition in human colon cancers. Yonsei Med J, 50, 818-24. DOI |
32 | Jin H, Yu Y, Zhangs T, et al (2010). Snail is critical for tumor growth and metastasis of ovarian carcinoma. Int J Cancer, 126, 2102-11. |
33 | Jang TJ, Cha WH, Lee KS (2010). Reciprocal correlation between the expression of cyclooxygenase-2 and E-cadherin in human bladder transitional cell carcinomas. Virchows Arch, 457, 319-28. DOI |
34 | Lee JS, Choi YD, Lee JH, et al (2006). Expression of cyclooxygenase-2 in epithelial ovarian tumors and its relation to vascular endothelial growth factor and p53 expression. Int J Gynecol Cancer, 16, 247-53. DOI |
35 | Li W, Wang J, Jiang HR, et al (2011). Combined Effects of Cyclooxygenase-1 and Cyclooxygenase-2 Selective Inhibitors on Ovarian Carcinoma in Vivo. Int J Mol Sci, 12, 668-81. DOI |
![]() |