• 한국과학교육학회지
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• 제40권5호
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• pp.503-514
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• 2020

성취 정서가 학생들의 성취 활동 및 결과와 직접으로 연관된 정서라는 점에서, 코로나 19로 인한 이러닝 수업의 확대와 같은 급격한 교육환경의 변화는 필연적으로 학생들의 성취 정서에 많은 영향을 줄 수 있다. 그러나 이에 대한 연구는 아직 부족한 실정이며, 이러닝 수업환경에서 학생들의 성취 정서를 정량적으로 측정할 수 있는 질문지의 개발은 관련 연구의 바탕이 될 수 있기에 본 연구에서는 이러닝 수업에서의 한국 중학생 과학영역 성취 정서 질문지(e-AEQ-KMS)를 타당화 과정을 거쳐 개발하였다. 본 연구에서 개발한 e-AEQ-KMS는 한국 중학생의 과학영역 성취 정서 질문지(AEQ-KMS)을 바탕으로 이러닝 과학 수업의 특징을 반영하여 개발되었다. 수업상황, 학습상황, 시험상황 등의 3가지 학업 상황에서 즐거움, 희망, 자부심, 안도감, 화, 불안, 지루함, 절망감, 수치심 등의 9가지 성취 정서를 측정할 수 있도록 구성되어 있으며 총 226문항이다. 내적, 외적 타당도를 검증한 결과, 질문지를 구성하는 각 문항은 높은 신뢰도를 보였으며 4가지 구성요인에 대한 확인적 요인분석(CFA)결과, 성취 정서가 정의적, 인지적, 동기적, 생리적이라고 하는 4개의 구성요인으로 이루어졌다고 가정한 모형이 그렇지 않다고 가정한 모형보다 더 타당하다는 결과를 얻었다. 성취 정서 사이의 상관분석을 통하여 각각의 성취 정서가 잘 변별됨을 확인하였고, 3가지 학업 상황 및 9가지 성취 정서의 잠재적 관계에 대해 확인적 요인분석(CFA)결과, 질문지에 반영된 모형이 가장 적합도가 높은 것으로 확인되었다. 통제-가치평가, 학습전략, 성취목표, 과학성적을 준거 변인으로 한 외적 타당도 검증 결과, 모든 준거 변인에 대하여 선행 연구와 동일한 결과를 보였으며 이를 통해 충분한 외적 타당도를 가짐을 확인하였다. 본 연구 결과는 이러닝 수업에서 한국 중학생들의 과학영역 성취 정서를 정량적으로 비교분석할 수 있는 틀을 마련했다는 점에서 큰 의의가 있다.

• Journal of Information Science Theory and Practice
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• 제7권3호
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• pp.6-20
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• 2019

Learning analytics, or educational data mining, is an emerging field that applies data mining methods and tools for the exploitation of data coming from educational environments. Learning management systems, like Moodle, offer large amounts of data concerning students' activity, performance, behavior, and interaction with their peers and their tutors. The analysis of these data can be elaborated to make decisions that will assist stakeholders (students, faculty, and administration) to elevate the learning process in higher education. In this work, the power of Excel is exploited to analyze data in Moodle, utilizing an e-learning course developed for enhancing the information computer technology skills of school teachers in primary and secondary education in Greece. Moodle log files are appropriately manipulated in order to trace daily and weekly activity of the learners concerning distribution of access to resources, forum participation, and quizzes and assignments submission. Learners' activity was visualized for every hour of the day and for every day of the week. The visualization of access to every activity or resource during the course is also obtained. In this fashion teachers can schedule online synchronous lectures or discussions more effectively in order to maximize the learners' participation. Results depict the interest of learners for each structural component, their dedication to the course, their participation in the fora, and how it affects the submission of quizzes and assignments. Instructional designers may take advice and redesign the course according to the popularity of the educational material and learners' dedication. Moreover, the final grade of the learners is predicted according to their previous grades using multiple linear regression and sensitivity analysis. These outcomes can be suitably exploited in order for instructors to improve the design of their courses, faculty to alter their educational methodology, and administration to make decisions that will improve the educational services provided.

• 대한한의학회지
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• 제29권5호
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• pp.67-76
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• 2008

Objectives : Amnesia is theloss or impairment of memory, caused by physical injury, disease, drugs, or emotional trauma. Recently, the average life span is increasing, while at the same time, the incidence of dementia-like diseases in conjunction with amnesia are also increasing. Therefore learning and memory are very important issues in modern society. Ancient Korean physicians used several herbs to treat dementia and these herbal effects were described in Korean herbal books. Among them are some reports on several cognitive-enhancing herbs which have since been shown to improve dementia in recent pharmacological studies, such as Panax ginseng; however, the facilitatory effects of many Korean cognitive-enhancing herbs on learning and memory are limited. Learning and memory are essential requirements for every living organism in order to cope with environmental demands; cholinergic systems are known to be involved in learning and memory. Methods : In this study, the effects of Acori graminei rhizoma (AGR, 石菖蒲) on learning and memory were investigated by Morris water maze, eight-arm radial maze, and the effects on the central cholinergic system of rats injected with scopolamine. Results : In the water maze, the experimental animals were trained to find a platform in a fixed position for 6 days and then received a 60 sec probe trial in which the platform was removed from the pool on the 7th day. In the eight-arm radial maze, the animals were tested four times per day for 6 days. Scopolamine impaired performance of the maze tests and reduced activity of acetylcholinesterase (AchE) in the hippocampus, which is a marker for the central cholinergic system. There were significant reversals from the scopolamine-induced deficits on learning and memory in these tests, through daily administrations of AGR (100 mg/kg, p.o.) over 14 consecutive days. These treatments also reduced the loss of cholinergic activity in the hippocampus induced by scopolamine. Conclusions : These results demonstrated that AGR ameliorated learning and memory deficits by affecting the central acetylcholine system.

• 지식경영연구
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• 제9권2호
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• pp.169-191
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• 2008

Information technology instruments arc being rampantly used for knowledge management in companies. IT is used as an interplay tool to enhance the flow of knowledge and information between people. KMS, especially, supports the knowledge management process including sharing, creating, and using of knowledge within a company, and maximizes the value of knowledge resources within an organization. The purpose of this paper is to understand how IT is changing the knowledge management activity. through various examples based on exploratory research from MANDO, the Korean automotive parts manufacturer, and POSCO, the global leading steelmaker. The result shows that IT boosts communication skills, thus creates a mutual relationship outcome. In the same context, the process of knowledge conversion by Nonaka's SECI model simplifies to an Externalization-Internalization process. This process accelerates the birth of explicit knowledge and Socialization, supplements the Limitations of the creation of knowledge in the E-I cycle. The E of knowledge simultaneously promotes the I, and eventually brings an advanced learning skill. IT aids the E of knowledge and furthermore, I and E activity, through the knowledge sharing, brings vitality into an organization. The interplay stage for knowledge activity is to be reorganized to a cyber ba. Furthermore, IT will galvanize the formation of core knowledge through systemized acquisition, management of core knowledge and standardization of work.

• 동의생리병리학회지
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• 제16권6호
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• pp.1236-1242
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• 2002

In order to make an efficient prescription and cope with dementia, learning and memory functions of Sprague-Dawley model rats were tested with Morris water maze. And to evaluate the effect of the sample drug(CHM) on choline acetyltranferase and acetylcholine esterase, immunoreactive measurement and enzymatic activity measuring were carried out. Rats were injected with ibotenic acid through hippocampus CA1 and CA3 area. The results are as following. CHM improves the learning ability in the acquisition test and memory function in the retention test significantly. And CHM increases the level of AChE which is resolving acetylcholine. Though it doesn't increase the level of ChAT significantly which is synthesizing acetylcholine, but it shows the tendency of increase. So these results show that CHM improve the cholinergic catabolism and anabolism, and the increment of metabolic activity of cholinergic system. Thus it can be concluded that CHM will be helpful to cholinergic brain disease induced by primary or senile reduction of acetylcholine secretive activity.

• 데이타베이스연구회지:데이타베이스연구
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• 제34권3호
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• pp.137-147
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• 2018

기계 학습을 통한 인간 동작 인지 (human activity recognition) 시스템에서 중요한 요소는 충분한 양의 라벨 데이터 (labeled data)를 확보하는 것이다. 그러나 라벨 데이터를 확보하는 일은 많은 비용과 시간을 필요로 한다. 매우 적은 수의 라벨 데이터를 가지고 있는 새로운 환경 (타겟 도메인)에서 동작 인지 시스템을 구축하는 경우, 기존의 환경 (소스 도메인)의 데이터나 이 환경에서 학습된 분류기(classifier)를 사용하는 것은 도메인이 서로 다르기 때문에 바람직하지 않다. 기존의 기계 학습 방법들이 이러한 문제를 해결할 수 없으므로 전이 학습 (transfer learning) 방법이 제시되었으며, 이 방법에서는 소스 도메인에서 확보한 지식을 활용하여 타겟 도메인에서의 분류기 성능을 높이도록 하고 있다. 본 논문에서는 다중 태스크 신경망 (multitask neural network)을 사용하여 매우 제한된 수의 데이터만으로 정확도가 높은 동작 인지 분류기를 생성하는 전이 학습방법을 제안한다. 이 방법에서는 소스 및 타겟 도메인 분류기의 손실 함수 최소화가 별개의 태스크로 간주된다. 즉, 하나의 신경망을 사용하여 두 태스크의 손실 함수를 동시에 최소화하는 방식으로 지식 전이(knowledge transfer)가 일어나게 된다. 또한, 제안한 방법에서는 모델 학습을 위하여 비지도 방식(unsupervised manner)으로 라벨이 부여되지 않은 데이터를 활용한다. 실험 결과, 제안한 방법은 기존의 방법에 비하여 일관적으로 우수한 성능을 보여주고 있다.

• The Korean Journal of Physiology and Pharmacology
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• 제18권3호
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• pp.201-209
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• 2014

The present study was designed to investigate the efficacy of selective $ET_A$ receptor antagonist, ambrisentan on hyperhomocysteinemia-induced experimental vascular dementia. L-methionine was administered for 8 weeks to induce hyperhomocysteinemia and associated vascular dementia in male rats. Ambrisentan was administered to L-methionine-treated effect rats for 4 weeks (starting from $5^{th}$ to $8^{th}$ week of L-methionine treatment). On $52^{nd}$ day onward, the animals were exposed to the Morris water maze (MWM) for testing their learning and memory abilities. Vascular endothelial function, serum nitrite/nitrate levels, brain thiobarbituric acid reactive species (TBARS), brain reduced glutathione (GSH) levels, and brain acetylcholinesterase (AChE) activity were also measured. L-methionine-treated animals showed significant learning and memory impairment, endothelial dysfunction, decrease in/serum nitrite/nitrate and brain GSH levels along with an increase in brain TBARS levels and AChE activity. Ambrisentan significantly improved hyperhomocysteinemia-induced impairment of learning, memory, endothelial dysfunction, and changes in various biochemical parameters. These effects were comparable to that of donepezil serving as positive control. It is concluded that ambrisentan, a selective $ET_A$ receptor antagonist may be considered as a potential pharmacological agent for the management of hyperhomocysteinemia-induced vascular dementia.

• 동의생리병리학회지
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• 제31권5호
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• pp.270-276
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• 2017

The aim of this study was to investigate the effects of the water extract of Albizziae Cortex (AC) on the learning and memory impairments. AC was administered to normal mouse and scopolamine-injected amnesia mouse model. Passive avoidance test, Y-maze test, and Morris water maze test were conducted to confirm the cognitive-enhancing activities of AC. Acetylcholinesterase (AChE) activity and acetylcholine (Ach) content were measured after oral administration of AC. On the passive avoidance test, AC (200 mg/kg) significantly increased latency time and recovered scopolamine-impaired learning and memory in mice. In addition, AC (200 mg/kg) reduced Exploration time in target quadrant and reversed the scopolamine-induced cognitive impairments in the Y-maze test. Moreover, AC (200 mg/kg) increased exploration time in target quadrant and improved scopolamine-reduced escape latencies in the Morris water maze test. These effects were presented by regulatory effects of AC on AChE activity and Ach content. Taken together, AC increases cognitive-enhancing activities and ameliorates scopolamine-induced learning and memory impairment. AC might be a potential agent for prevention and treatment of amnesia and dementia.

• 지식경영연구
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• 제6권1호
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• pp.33-69
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• 2005

Recently, knowledge management and E-business are very important issues in academic and business fields. Research questions related with these issues are which factors stimulate knowledge management. Another question is whether knowledge management is related to E-business. To answer these questions a research model was proposed. The data were collected from 90 manufacturing firms in Korea. Appropriate research methodologies were employed for analysis. Results found that the degree of firm's internalization, diversity of domestic management activities and learning orientation affect knowledge aquisition and transfer. Knowledge aquisition and transfer facilitate knowledge application, resulting in new product development, cost reduction and technology differentiation. Knowledge management is a kind of process. This result, therefore, confirms what previous literature predicted.

• 대한본초학회지
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• 제37권4호
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• pp.39-48
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• 2022

Objectives : In the present study, we assessed the effects of water extract of Ulmus davidiana(UED) on the learning and memory impairments induced by scopolamine in mice through its favorable acetylcholinesterase (AChE) activity and antioxidant effect. Methods : The memory and cognitive enhancing effect of the UDE was investigated using a passive avoidance test, the Morris water maze test and Y-maze test in mice. In addition, to examine the mechanism of UDE using acetylcholinesterase (AChE) and antioxidant activity. Results : The water extract of UDE (100, and 200 mg/kg) significantly reversed the scopolamine-induced cognitive impairments in the passive avoidance test (P < 0.05). Moreover, UDE (100, and 200 mg/kg) also improved escape latencies in training trials and increased swimming times and distances within the target zone of the Morris water maze (P < 0.05). On the Y-maze test, UDE (100, and 200 mg/kg) also significantly reversed scopolamine-induced cognitive impairments in mice (P < 0.05). In an in vitro study, UDE was found to inhibit acetylcholinesterase, changes in neurotrophic factor (CREB), and antioxidant activity in a dose-dependent manner. Conclusions : The water extract of UDE dramatically possesses the anti-amnestic and cognitive-enhancing activities related to the memory processes, and these activities were parallel to treatment duration and dependent on the learning models. These results suggest that the administration of UDE enhances learning and memory, and that this effect is partially mediated by ERK-CREB-BDNF signaling and the survival of immature neurons.