• Journal of the Korea Computer Graphics Society
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• v.24 no.5
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• pp.41-48
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• 2018

The most natural way to increase immersion and provide free interaction in a virtual environment is to provide a gesture interface using the user's hand. However, most studies about hand gesture recognition require specialized sensors or equipment, or show low recognition rates. This paper proposes a three-dimensional DenseNet Convolutional Neural Network that enables recognition of hand gestures with no sensors or equipment other than an RGB camera for hand gesture input and introduces a virtual reality game based on it. Experimental results on 4 static hand gestures and 6 dynamic hand gestures showed that they could be used as real-time user interfaces for virtual reality games with an average recognition rate of 94.2% at 50ms. Results of this research can be used as a hand gesture interface not only for games but also for education, medicine, and shopping.

• Tuberculosis and Respiratory Diseases
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• v.82 no.2
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• pp.126-132
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• 2019

Background: The development of lung cancer results from the interaction between genetic mutations and dynamic epigenetic alterations, although the exact mechanisms are not completely understood. Changes in DNA methylation may be a promising biomarker for early detection and prognosis of lung cancer. We evaluated the serial changes in genome-wide DNA methylation patterns in blood samples of lung cancer patients. Methods: Blood samples were obtained for three consecutive years from three patients (2 years before, 1 year before, and after lung cancer detection) and from three control subjects (without lung cancer). We used the MethylationEPIC BeadChip method, which covers the 850,000 bp cytosine-phosphate-guanine (CpG) site, to conduct an epigenome-wide analysis. Significant differentially methylated regions (DMRs) were identified using p-values <0.05 in a correlation test identifying serial methylation changes and serial increase or decrease in ${\beta}$ value above 0.1 for three consecutive years. Results: We found three significant CpG sites with differentially methylated ${\beta}$ values and 7,105 CpG sites with significant correlation from control patients without lung cancer. However, there were no significant DMRs. In contrast, we found 11 significant CpG sites with differentially methylated ${\beta}$ values and 10,562 CpG sites with significant correlation from patients with lung cancer. There were two significant DMRs: cg21126229 (RNF212) and cg27098574 (BCAR1). Conclusion: This study revealed DNA methylation changes that might be implicated in lung cancer development. The DNA methylation changes may be the possible candidate target regions for the early detection and prevention of lung cancer.

• Communications of Mathematical Education
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• v.35 no.1
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• pp.37-74
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• 2021

In this study, the student participation-centered class, which takes students' mathematical thinking as an important issues of the class, is named as student thinking-based math class. The main characteristics of student thinking-based mathematics classes were examined in terms of tasks, students engagement, and the role of teachers. According to the results of analysis of class cases practiced by five secondary mathematics teachers, student thinking-based mathematics classes were conducted in the intersection of the rich mathematics tasks, students' cognitive and social engagement, and the role of teachers' formative facilitator. The results of this study showed that the student's thinking is more important than the activity itself. And it is meaningful in that it examines the influence of the dynamic interaction of the three components of the mathematics class on the direction and outcome of the class.

• International Journal of Internet, Broadcasting and Communication
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• v.13 no.1
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• pp.47-53
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• 2021

Gait kinematics and kinetics have a similar tendency between men and women, yet it remains unclear how walking while carrying a load affects the gait mechanism. Twenty adults walked with preferred velocity on level ground of 20 m relative to change of a load carriage (no load, 15%, 30% of the body weights) aimed to observe gait mechanism. We measured gait posture using the three-dimensional image analysis and ground reaction force system during stance phase on left foot. In main effect of gender difference, men showed increased displacement of center of gravity (COG) compared to women, and it showed more extended joint angle of hip and knee in sagittal plane. In main effect of a load difference, knee joint showed more flexed postuel relative to increase of load carriage. In main effect of load difference on the kinetic variables, medial-lateral force, anterior-posterior force (1st breaking, 2nd propulsive), vertical force, center of pressure (COP) area, leg stiffness, and whole body stiffness showed more increased values relative to increase of load carriage. Also, men showed more increased COP area compared to women. Interaction showed in the 1st anterior-posterior force, and as a result of one-way variance analysis, it was found that a load main effect had a greater influence on the increase in the magnitude of the braking force than the gender. The data in this study explains that women require little kinematic alteration compared to men, while men in more stiff posture accommodate an added load compared to women during gait. Additionally, it suggests that dynamic stability is maintained by adopting different gait strategies relative to gender and load difference.

• The Korean Journal of Franchise Management
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• v.10 no.3
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• pp.13-23
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• 2019

Purpose - The recent franchise industry is rapidly developing. Some franchisees have a low barriers to entry and competition among companies is intensifying. In this dynamic competitive environment, companies need to focus on customer preferences, quality, and technical interfaces to gain competitive advantage. As a result, companies are required to measure the performance of service values in order to provide differentiated services from competitors. In the franchise industry, customer experience marketing of service values will enable companies to create new businesses. Franchise firms should explore a variety of services to increase service value and reduce failures. Research design, data, methodology - The questionnaire of this study was based on the previous research. Surveys were conducted on panels of online surveys. Surveys were conducted on the panel who had visited the restaurant franchise within the past month. The survey was conducted for about 7 days from February 13, 2019 to February 19, 2019. Total 300 samples, 293 were used in the analysis except for seven unfair questionnaires. Results - The findings of this study are as follows: Emotional, monetary, and reputation values have positive effects on cognitive and affective attitudes. Quality value and behavioral value did not effect cognitive attitude and affective attitude significantly. In addition, affective attitude has positive effect on loyalty, but cognitive attitude did not significant effect on loyalty. Conclusions - First, food-service franchise company should develop a service that enables customers to use the store conveniently. We need to develop a comfortable environment for our customers and provide intangible services. Second, food-service franchise company should provide a reasonable price service. Food-service franchise company needs to sell a high quality menu at a reasonable price to generate profits. Third, food-service franchise companies need to strategically respond to their reputation. In other words, food-service franchise company needs to constantly monitor the reputation of its customers and respond appropriately to market conditions. Fourth, food-service franchise company needs to develop a service method capable of emotional interaction with customers. Food-service franchise firms need to develop ongoing service methods and educate their staff.

• Journal of the Korea Society for Simulation
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• v.30 no.1
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• pp.43-54
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• 2021

Since COVID-19 (Severe acute respiratory syndrome coronavirus type 2, SARS-Cov-2) was first discovered at the end of 2019, it has spread rapidly around the world. This study introduces an agent-based simulation model representing COVID-19 spread in South Korea to investigate the effect of detect level (contact tracing) on the virus spread. To develop the model, related data are aggregated and probability distributions are inferred based on the data. The entire process of infection, quarantine, recovery, and death is schematically described and the interaction of people is modeled based on the traffic data. A composite logistic functions are utilized to represent the compliance of people to the government move control such as social distancing. To demonstrate to effect of detect level on the virus spread, detect level is changed from 0% to 100%. The results indicate active contact tracing inhibits the virus spread and the inhibitory effect increases geometrically as the detect level increases.

• Journal of the Earthquake Engineering Society of Korea
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• v.26 no.3
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• pp.105-116
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• 2022

Seismic demand on nonstructural components (NSCs) is highly dependent on the coupled behavior of a combined supporting structure-NSC system. Because of the inherent complexities of the problem, many of the affecting factors are inevitably neglected or simplified based on engineering judgments in current seismic design codes. However, a systematic analysis of the key affecting factors should establish reasonable seismic design provisions for NSCs. In this study, an idealized 2-DOF model simulating the coupled structure-NSC system was constructed to analyze the parameters that affect the response of NSCs comprehensively. The analyses were conducted to evaluate the effects of structure-NSC mass ratio, structure, and NSC nonlinearities on the peak component acceleration. Also, the appropriateness of component ductility factor (R_p) given by current codes was discussed based on the required ductility capacity of NSCs. It was observed that the responses of NSCs on the coupled system were significantly affected by the mass ratio, resulting in lower accelerations than the floor spectrum-based response, which neglected the interaction effects. Also, the component amplification factor (a_p) in current provisions tended to underestimate the dynamic amplification of NSCs with a mass ratio of less than 15%. The nonlinearity of NSCs decreased the component responses. In some cases, the code-specified R_p caused nonlinear deformation far beyond the ductility capacity of NSCs, and a practically unacceptable level of ductility was required for short-period NSCs to achieve the assigned amount of response reduction.

• Advances in Computational Design
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• v.7 no.3
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• pp.229-251
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• 2022

In 2017, an intraplate earthquake of Mw 7.1 occurred 120 km from Mexico City (CDMX). Most collapsed structural buildings stroked by the earthquake were flat slab systems joined to reinforced concrete (RC) columns, unreinforced masonry, confined masonry, and dual systems. This article presents the simulated response of an actual six-story RC frame building with masonry infill walls that did not collapse during the 2017 earthquake. It has a structural system similar to that of many of the collapsed buildings and is located in a high seismic amplification zone. Five 3D numerical models were used in the study to model the seismic response of the building. The building dynamic properties were identified using an ambient vibration test (AVT), enabling validation of the building's finite element models. Several assumptions were made to calibrate the numerical model to the properties identified from the AVT, such as the presence of adjacent buildings, variations in masonry properties, soil-foundation-structure interaction, and the contribution of non-structural elements. The results showed that the infill masonry wall would act as a compression strut and crack along the transverse direction because the shear stresses in the original model (0.85 MPa) exceeded the shear strength (0.38 MPa). In compression, the strut presents lower stresses (3.42 MPa) well below its capacity (6.8 MPa). Although the non-structural elements were not considered to be part of the lateral resistant system, the results showed that these elements could contribute by resisting part of the base shear force, reaching a force of 82 kN.

• Development and Reproduction
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• v.24 no.4
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• pp.249-261
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• 2020

Spermatogonial stem cells (SSCs) have stemness characteristics, including germ cell-specific imprints that allow them to form gametes. Spermatogenesis involves changes in gene expression such as a transition from expression of somatic to germ cell-specific genes, global repression of gene expression, meiotic sex chromosome inactivation, highly condensed packing of the nucleus with protamines, and morphogenesis. These step-by-step processes finally generate spermatozoa that are fertilization competent. Dynamic epigenetic modifications also confer totipotency to germ cells after fertilization. Primordial germ cells (PGCs) in embryos do not enter meiosis, remain in the proliferative stage, and are referred to as gonocytes, before entering quiescence. Gonocytes develop into SSCs at about 6 days after birth in rodents. Although chromatin structural modification by Polycomb is essential for gene silencing in mammals, and epigenetic changes are critical in spermatogenesis, a comprehensive understanding of transcriptional regulation is lacking. Recently, we evaluated the expression profiles of Yin Yang 1 (YY1) and CP2c in the gonads of E14.5 and 12-week-old mice. YY1 localizes at the nucleus and/or cytoplasm at specific stages of spermatogenesis, possibly by interaction with CP2c and YY1-interacting transcription factor. In the present article, we discuss the possible roles of YY1 and CP2c in spermatogenesis and stemness based on our results and a review of the relevant literature.

• Structural Engineering and Mechanics
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• v.83 no.5
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• pp.627-644
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• 2022

In past major earthquakes (1994 Northridge, 1995 Kobe, Chi-Chi 1999, Kocaeli 1999), significant damages occurred in the liquid storage tanks. The basic failure patterns were observed to be the buckling of the tank wall and uplift of the anchorage system. The damages in the industrial facilities and nuclear power plants have caused the spread of toxic substances to the environment and significant fires. Seismic isolation can be used in liquid storage tanks to decouple the structure and decrease the structural demand in the superstructure in case of ground shaking. Previous studies on the use of seismic isolation systems on liquid storage tanks show that an isolation system reduces the impulsive response but might slightly increase the convective one. There is still a lack of understanding of the seismic response of seismically isolated liquid storage tanks considering the fluid-structure interaction. In this study, one broad tank, one medium tank, and one slender tank are selected and designed. Two- and three-dimensional elastomeric bearings are used as seismic isolation systems. The seismic performance of the tanks is then investigated through nonlinear dynamic time-history analyses. The effectiveness of each seismic isolation system on tanks' performance was investigated. Isolator tension forces, modal analysis results, hydrodynamic stresses, strains, sloshing heights and base shear forces of the tanks are compared. The results show that the total base shear is lower in 3D-isolators compared to 2D-isolators. Even though the tank wall stresses, and strains are slightly higher in 3D-isolators, they are more efficient to prevent the tension problem.