• Title/Summary/Keyword: dynamic compartment model

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Model for predicting the $^{137}C_s$ contamination of an agricultural plant following a soil deposition (토양침적에 의한 $^{137}C_s$ 농작물 오염평가 모델)

  • Jun, In;Keum, Dong-Kwon;Kang, Hee-Seok;Choi, Yong-Ho;Lee, Han-Soo;Lee, Chang-Woo
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.4 no.4
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    • pp.365-372
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    • 2006
  • A dynamic compartment model is presented to predict the contamination level of agricultural plant by $^{137}C_s$ as a result of a soil deposition. The model considered the processes of a percolation, soil mixing by a plowing before transplanting, plant uptake, leaching to a deep soil, and fixation to a clay mineral. The effects of the soil properties (pH, clay mineral, organic matter content, and exchangeable K), which are spatially varied, on a plant uptake and the leaching rates of $^{137}C_s$ in a root zone soil were modeled by the Absalom model. To test the validity of the model, the $^{137}C_s$ aggregated transfer factors(TFa) for rice plants were compared with those observed from some simulated $^{137}C_s$ soil deposition experiments, which were carried out with respect to rice plants cultivated in seventeen paddy soils of different properties for two consecutive years. Observed $^{137}C_s$ TFa values of the rice plants did not show an evident trend for the pH and clay content of the soil properties, while they increased with an increasing organic matter content or a decreasing exchangeable K concentration. Predicted $^{137}C_s$ TFa values of the rice plants were found to be comparable with those observed.

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Steady states and dynamic behavior of an LDPE autoclave reactor

  • Lee, Jin-Suk;Chang, Kil-Sang;Kim, Jae-Yeon;Rhee, Hyun-Ku
    • 제어로봇시스템학회:학술대회논문집
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    • 1989.10a
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    • pp.813-818
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    • 1989
  • A two compartmented autoclave reactor for the polymerization of low density polyethylene is analyzed with respect to the effects of heat transfer and operation variables. Each compartment being considered as a completely mixed cell, two CSTRs model is proposed. The system shows various multiplicity features of steady state and periodic oscillatory motions. Heat removal efficiency and initiator supplement appear to have significant effect on the conversion of monomer with the temperature properly maintained, which should be taken into account in the reactor design.

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Transfer Path Analysis on the Passenger Car Interior Noise (승용차 실내소음의 전달경로 해석)

  • 지태한;최윤봉
    • Journal of KSNVE
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    • v.9 no.1
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    • pp.97-102
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    • 1999
  • Structure-borne noise is an important aspect to consider during the design and development of a vehicle. In this work. it was desired to identify the primary paths associated with structure-borne noise generated from the engine and front suspension. An experimental source-path-receiver model was used to characterize the system. A variety of primary sources such as engine. tires or exhaust system generate vibrations of the inner surfaces of the passenger compartment of a vehicle which subsequently radiate noise. The source was characterized by the force acting at the engine-to-body interface. and the path was characterized by pressure over force FRF's. The excitation forces were indirectly determined using dynamic stiffness of rubber mount or the system accelerance matrix. Through these analysis, path contribution diagram which is well expressed primary noise path is obtained.

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Quantification of myocardial blood low using dynamic N-13 ammonia PET and actor analysis (N-13 암모니아 PET 동적영상과 요소분석을 이용한 심근 혈류량 정량화 방법 개발)

  • Kim, J.Y.;Choi, Y.;Im, K.C.;Choe, Y.S.;Lee, K.H.;Kim, S.E.;Kim, Y.J.;Kim, B.T.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.11
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    • pp.575-578
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    • 1997
  • Myocardial blood low (MBF) in human can be noninvasively quantified using dynamic N-13 ammonia PET and two-compartment tracer kinetic model. In this study, factor analysis was used to extract the "pure" blood-pool time-activity curves (TACs) and to generate actor images. ive human N-13 ammonia PET dynamic studies were obtained. Three actors and their corresponding actor images were extracted rom each study. The accuracy of MBF estimated by the actor analysis (FA/FA MBF) was examined by comparing to the values estimated using the conventional ROI method (ROI/ROI MBF). MBF obtained by the actor analysis linearly correlated with MBF obtained by the ROI method (slope=0.98, r=0.91). Input unctions obtained by the two methods agreed well. In conclusion, MBF can be measured accurately and noninvasively with dynamic N-13 ammonia PET imaging and actor analysis. This method is simple and acurate and can measure MBF without blood sampling, ROI drawing nor spillover correction.

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A Refined Method for Quantification of Myocardial Blood Flow using N-13 Ammonia and Dynamic PET (N-13 암모니아와 양전자방출단층촬영 동적영상을 이용하여 심근혈류량을 정량화하는 새로운 방법 개발에 관한 연구)

  • Kim, Joon-Young;Lee, Kyung-Han;Kim, Sang-Eun;Choe, Yearn-Seong;Ju, Hee-Kyung;Kim, Yong-Jin;Kim, Byung-Tae;Choi, Yong
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.1
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    • pp.73-82
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    • 1997
  • Regional myocardial blood flow (rMBF) can be noninvasively quantified using N-13 ammonia and dynamic positron emission tomography (PET). The quantitative accuracy of the rMBF values, however, is affected by the distortion of myocardial PET images caused by finite PET image resolution and cardiac motion. Although different methods have been developed to correct the distortion typically classified as partial volume effect and spillover, the methods are too complex to employ in a routine clinical environment. We have developed a refined method incorporating a geometric model of the volume representation of a region-of-interest (ROI) into the two-compartment N-13 ammonia model. In the refined model, partial volume effect and spillover are conveniently corrected by an additional parameter in the mathematical model. To examine the accuracy of this approach, studies were performed in 9 coronary artery disease patients. Dynamic transaxial images (16 frames) were acquired with a GE $Advance^{TM}$ PET scanner simultaneous with intravenous injection of 20 mCi N-13 ammonia. rMBF was examined at rest and during pharmacologically (dipyridamole) induced coronary hyperemia. Three sectorial myocardium (septum, anterior wall and lateral wall) and blood pool time-activity curves were generated using dynamic images from manually drawn ROIs. The accuracy of rMBF values estimated by the refined method was examined by comparing to the values estimated using the conventional two-compartment model without partial volume effect correction rMBF values obtained by the refined method linearly correlated with rMBF values obtained by the conventional method (108 myocardial segments, correlation coefficient (r)=0.88). Additionally, underestimated rMBF values by the conventional method due to partial volume effect were corrected by theoretically predicted amount in the refined method (slope(m)=1.57). Spillover fraction estimated by the two methods agreed well (r=1.00, m=0.98). In conclusion, accurate rMBF values can be efficiently quantified by the refined method incorporating myocardium geometric information into the two-compartment model using N-13 ammonia and PET.

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Assessing the Activity Concentration of Agricultural Products and the Public Ingestion Dose as Result of a Nuclear Accident

  • Keum, Dong-Kwon;Jeong, Hyojoon;Jun, In;Lim, Kwang-Muk;Choi, Yong-Ho
    • Journal of Radiation Protection and Research
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    • v.43 no.2
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    • pp.39-49
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    • 2018
  • Background: A model to assess the activity concentration of agricultural products and the public ingestion dose as result of a nuclear accident is necessarily required to manage the contaminated agricultural systems by the accident, or to estimate the effects of chronic exposure due to food ingestion at a Level 3 PSA. Materials and Methods: A dynamic compartment model, which is composed of three sub-modules, namely, an agricultural plant contamination assessment model, an animal product contamination assessment model, and an ingestion dose assessment model has been developed based on Korean farming characteristics such as the growth characteristics of rice and stockbreeding. Results and Discussion: The application study showed that the present model can predict well the characteristics of the activity concentration for agricultural products and ingestion dose depending on the deposition date. Conclusion: The present model is very useful to predict the radioactivity concentration of agricultural foodstuffs and public ingestion dose as consequence of a nuclear accident. Consequently, it is expected to be used effectively as a module for the ingestion dose calculation of the Korean agricultural contamination management system as well as the Level 3 PSA code, which is currently being developed.

Kinetic analysis of 64Cu-NODAGA-gluco-E[c(RGDfK)]2 for a tumor angiogenesis PET tracer

  • Choi, Jae Yong;Park, Ji-Ae;Kim, Jung Young;Lee, Ji Woong;Lee, Minkyung;Shin, Un Chol;Kang, Joo Hyun;An, Gwang Il;Lee, Kyo Chul;Ryu, Young Hoon;Kim, Kyeong Min
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.2 no.2
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    • pp.108-112
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    • 2016
  • Molecular imaging with the radiolabeled RGD peptides for ${\alpha}_v{\beta}_3$ integrin has been an increasing interest for tumor diagnosis and the treatment monitoring. Recently, $^{64}Cu$-NODAGA-gluco-E[c(RGDfK)]$_2$ was developed for quantification of ${\alpha}_v{\beta}_3$ integrin and its biological properties was elucidated. To better understand the molecular process in vivo, we performed the kinetic analysis for the $^{64}Cu$-NODAGA-gluco-E[c(RGDfK)]$_2$. After preparation of a radiotracer, dynamic PET images were obtained in the U87MG xenograft mice for 60 min (n = 6). Binding potential values were estimated from the 3-tissue compartment model, reference Logan and simplified reference tissue model. In the early time frame (0-20 min), the liver, kidney, intestine, urinary bladder and tumor were visualized but these uptakes were diminished as time went by. The tumors showed a good contrast at 40 min after administration. $^{64}Cu$-NODAGA-gluco-E[c(RGDfK)]$_2$ showed the 2-fold uptake in the tumor compared with that in the muscle. The parametric maps for binding values also provide the higher tumor-to-background contrast than the static images. A binding value obtained from the 3-tissue compartment model was comparable to other modeling methods. From these results, we conclude that $^{64}Cu$-NODAGA-gluco-E[c(RGDfK)]$_2$ may be a promising PET radiotracer for the evaluation of angiogenesis.

Investigation of Dynamic Characteristics of the Flooding Water of the Damaged Compartment of an ITTC RoRo-Passenger (ITTC RoRo-Passenger 손상부위 침수유동 특성에 관한 연구)

  • Cho Seok-Kyu;Hong Sa-Young;Kim Yoon-Ho
    • Journal of the Society of Naval Architects of Korea
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    • v.43 no.4 s.148
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    • pp.451-459
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    • 2006
  • When a ship is damaged and flooded, the motion of the damaged ship is significantly influenced by the flooding water dynamics. The flooding water in the damaged ship has been treated as a lumped mass under the quasi-static assumption in most of previous researches. To calculate the motion of damaged ship rigorously, it is necessary to analyze the coupled dynamics of flooding water. In this study, a series of numerical and experimental studies is conducted for the damaged part of ITTC RORO passenger. FLOW3D is used for investigating the feasibility of the state of the art CFD technique. An applicability of the coupled motion analysis of damaged ships can be confirmed by agreement between the numerical results and the model experiments. A CFD technique is considered for the numerical modeling of the dynamics of flooding water.

Estimation of Tritium Concentration in the Environment based upon Global Tritium Cycling Model (글로벌 삼중수소 순환 모델을 이용한 삼중수소 환경 방사능 추정)

  • Choi, Heui-Joo;Lee, Han-Soo;Kang, Hee-Suk;Lee, Chang-Woo
    • Journal of Radiation Protection and Research
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    • v.28 no.1
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    • pp.1-8
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    • 2003
  • The periodic safety review of operational nuclear power plants requires that the plants should keep a well organized environmental monitoring program. The past records of environment monitoring data were analyzed. and the tritium concentrations of the samples in the surface and ground water around Kori site were measured. It was shown that the tritium concentrations around the Kori site were slightly higher than that of natural background. The change of background tritium concentration was estimated through a numerical modeling. Two different versions of 7 compartments model - the world and the northern hemisphere - defined in NCRP-62 were modeled for the global tritium cycling. The numerical solution of the model was obtained using a computer program, AMBER. The four cases of tritium source-terms into the atmosphere were considered. The results showed that the tritium concentration in the surface soil water was higher than that in sea water or surface stream water. Also, it was shown that the tritium produced by the interaction between cosmic rays and the gases were the major source of tritium, and the tritium produced by nuclear weapon test decreased considerably.

Predicting of the $^{14}C$ Activity in Rice Plants Exposed to $^{14}CO_2$ Gas for a Short Period of Time ($^{14}CO_2$가스에 단기간 노출된 벼의 $^{14}C$ 오염 예측)

  • Jun, In;Lim, Kwang-Muk;Keum, Dong-Kwon;Choi, Young-Ho;Han, Moon-Hee
    • Journal of Radiation Protection and Research
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    • v.33 no.4
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    • pp.135-141
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    • 2008
  • This paper describes a dynamic compartment model to predict the time-dependent $^{14}C$ activity in a plant as a result of a direct exposure to an amount of $^{14}CO_2$ for a short period of time, and experimental results for the model validation. In the model, the plant consists of two compartments of the body and ears, and five carbon fluxes between the compartments, which are the function of parameters relating to the growth and photosynthesis of a plant, are considered. Model predictions were made for an investigation into the effects of the exposure time, the elapsed exposure time, and the model parameters on the $^{14}C$ radioactivity of a plant. The present model converged to a region where the specific activity model is applicable when the elapsed time of the exposure was extended up to the harvest time of a plant. The $^{14}C$ activity of a plant was predicted to be the greatest when the exposure had happened in the period between the flowering and ears-maturity on account of the most vigorous photosynthesis rate for the period. Comparison of model predictions with the observed 14C radioactivity of rice plants showed that the present model could predict the $^{14}C$ radioactivity of the rice plants reasonably well.