Proceedings of the KOSOMBE Conference (대한의용생체공학회:학술대회논문집)
- Volume 1997 Issue 11
- /
- Pages.575-578
- /
- 1997
Quantification of myocardial blood low using dynamic N-13 ammonia PET and actor analysis
N-13 암모니아 PET 동적영상과 요소분석을 이용한 심근 혈류량 정량화 방법 개발
- Kim, J.Y. (Department of Physics, Hanyang University) ;
-
Choi, Y.
(Department of Nuclear Medicine, Samsung Seoul Hospital)
;
- Im, K.C. (Department of Nuclear Medicine, Samsung Seoul Hospital) ;
-
Choe, Y.S.
(Department of Nuclear Medicine, Samsung Seoul Hospital)
;
-
Lee, K.H.
(Department of Nuclear Medicine, Samsung Seoul Hospital)
;
-
Kim, S.E.
(Department of Nuclear Medicine, Samsung Seoul Hospital)
;
- Kim, Y.J. (Department of Physics, Hanyang University) ;
- Kim, B.T. (Department of Nuclear Medicine, Samsung Seoul Hospital)
- 김준영 (한양대학교 물리학과) ;
-
최용
(삼성서울병원 핵의학과)
;
- 임기천 (삼성서울병원 핵의학과) ;
-
최연성
(삼성서울병원 핵의학과)
;
-
이경한
(삼성서울병원 핵의학과)
;
-
김상은
(삼성서울병원 핵의학과)
;
- 김영진 (한양대학교 물리학과) ;
- 김병태 (삼성서울병원 핵의학과)
- Published : 1997.11.28
Abstract
Myocardial blood low (MBF) in human can be noninvasively quantified using dynamic N-13 ammonia PET and two-compartment tracer kinetic model. In this study, factor analysis was used to extract the "pure" blood-pool time-activity curves (TACs) and to generate actor images. ive human N-13 ammonia PET dynamic studies were obtained. Three actors and their corresponding actor images were extracted rom each study. The accuracy of MBF estimated by the actor analysis (FA/FA MBF) was examined by comparing to the values estimated using the conventional ROI method (ROI/ROI MBF). MBF obtained by the actor analysis linearly correlated with MBF obtained by the ROI method (slope=0.98, r=0.91). Input unctions obtained by the two methods agreed well. In conclusion, MBF can be measured accurately and noninvasively with dynamic N-13 ammonia PET imaging and actor analysis. This method is simple and acurate and can measure MBF without blood sampling, ROI drawing nor spillover correction.
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