• Title/Summary/Keyword: dual basis

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Opioid Pharmacotherapy for Chronic Noncancer Pain: The American Experience

  • Chapman, C. Richard
    • The Korean Journal of Pain
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    • v.26 no.1
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    • pp.3-13
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    • 2013
  • Chronic noncancer pain is a significant and growing public health challenge in the United States. Lacking effective alternative interventions for effective chronic noncancer pain management, many physicians have turned to opioid pharmacotherapy. Increased opioid prescribing brings not only gains in therapeutic benefit but also a higher incidence of adverse drug events including increased medication misuse and opioid related mortality. Currently the United States must confront the dual problems of widespread undertreated chronic noncancer pain and a prescription opioid abuse crisis. Withholding pain relieving drugs from patients in need is unjustifiable, yet drug diversion, abuse and adverse drug events have become major social as well as medical problems. At the heart of this crisis is the lack of definitive evidence about the risk to benefit ratio of opioid pharmacotherapy for chronic noncancer pain both on an individual case and on a population basis. This article describes the extent and severity of the American chronic noncancer pain problem and the history of opioid pharmacotherapy for chronic noncancer pain in the United States. It then discusses the concept of evidence based practice and reviews current evidence supporting opioid pharmacotherapy for chronic noncancer pain as well as adverse drug events related to opioid pharmacotherapy including misuse and abuse. Finally, it considers the conflict of providing pain relief versus protecting society and reviews steps that governmental agencies, industry and others are taking to contain and ultimately resolve the problems of excessive prescribing and conflicting priorities.

Design of Transceiver Front-end using Circular Sector Patch Antenna (원형 섹터 패치 안테나를 사용한 트랜시버 전단부 설계)

  • ;Tatsuo Itohv
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.5 no.4
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    • pp.807-811
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    • 2001
  • In this paper we proposed a dual-frequency circular sector microstrip antenna with orthogonal polarized modes and high isolation between the two feeding ports. And then we designed a transceiver operating at 5.6 GHz for transmitting and at 5.5 GHz for receiving. The good isolation provided by the proposed antenna is used as the basis for the transmit-receive filtering of transceiver. The operating frequencies and polarization characteristics of the proposed antenna is calculated by using a cavity model. The 5-parameters and radiation patterns of the antenna are measured. A power amplifier and a low noise amplifier are designed and integrated with antenna to make a transceiver, which has about 13dB transmitting gain and about 8㏈ receiving gain.

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Design of Flipped Learning with Strategic Questioning to Improve Student's Problem-Solving Competency in Engineering (공학생의 문제해결력 향상을 위한 질문생성 전략 활용 플립러닝 수업 설계)

  • Rim, Kyung-hwa;An, Jung-hyun
    • Journal of Practical Engineering Education
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    • v.8 no.2
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    • pp.75-81
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    • 2016
  • This research proposes to design a flipped classroom with strategic questioning to enhance engineering student's creative problem-solving competency on the basis of the subject knowledge. By applying the designed flipped classroom to both of college and dual system engineering courses during one semester, this study explores to find the meaning and effects of the flipped learning method. The case study analyzed the influences of the flipped learning with the use of strategic questioning on student's problem-solving performance, and also investigated student satisfaction and evaluation of the learning in order to draw out the factors to consider further in the instructional design.

Diagnostic Imaging of Portosystemic Shunt using CT in Two Dogs (전산화단층촬영을 이용한 문맥전신단락의 진단 증례)

  • Jung, Joo-Hyun;Chae, Woong-Joo;Chang, Jin-Hwa;Chae, Ho-Cheol;Kim, Wan-Hee;Lee, Ki-Chang;Yoon, Jung-Hee;Choi, Min-Cheol
    • Journal of Veterinary Clinics
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    • v.24 no.3
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    • pp.461-466
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    • 2007
  • Two dogs were admitted with a history of anorexia, ataxia, shivering, lethargy, hypersalivation and seizure. Patients were suspected for portosystemic shunts on the basis of clinical signs, increased hepatic serum profiles on the blood test, microhepatica on plain abdominal radiographs, and an abnormally dilated and tortuous vessel on abdominal ultrasonographs. To diagnose PSS and to further evaluate type, shape, and location of shunt and hepatic vasculatures, the computed tomography (CT) angiography for portal and systemic circulation was performed. The shape, location and pathway of extrahepatic single shunt were confirmed in two dogs. Dual phases (the arterial phase and the venous phase) CT angiography and reformatted and three-dimensional images offered good understanding of PSS and planning surgical treatment.

Type Drive Analysis of Urban Water Security Factors

  • Gong, Li;Wang, Hong;Jin, Chunling;Lu, Lili;Ma, Menghan
    • Journal of Information Processing Systems
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    • v.16 no.4
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    • pp.784-794
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    • 2020
  • In order to effectively evaluate the urban water security, the study investigates a novel system to assess factors that impact urban water security and builds an urban water poverty evaluation index system. Based on the contribution rates of Resource, Access, Capacity, Use, and Environment, the study adopts the Water Poverty Index (WPI) model to evaluate the water poverty levels of 14 cities in Gansu during 2011-2018 and uses the least variance method to evaluate water poverty space drive types. The case study results show that the water poverty space drive types of 14 cites fall into four categories. The first category is the dual factor dominant type driven by environment and resources, which includes Lanzhou, Qingyang, Jiuquan, and Jiayuguan. The second category is the three-factor dominant type driven by Access, Use, and Capability, which includes Longnan, Linxia, and Gannan. The third category is the four-factor dominant type driven by Resource, Access, Capability, and Environment, which includes Jinchang, Pingliang, Wuwei, Baiyin, and Zhangye. The fourth category is the five-factor dominant type, which includes Tianshui and Dingxi. The driven types impacting the urban water security factors reflected by the WPI and its model are clear and accurate. The divisions of the urban water security level supply a reliable theoretical and numerical basis for an urban water security early warning mechanism.

Performance Analysis of a Stand-alone Brushless Doubly-fed Induction Generator Using a New T-type Steady-state Model

  • Liu, Yi;Xu, Wei;Zhi, Gang;Zhang, Junlin
    • Journal of Power Electronics
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    • v.17 no.4
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    • pp.1027-1036
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    • 2017
  • The brushless doubly-fed induction generator (BDFIG) is a new type of dual stator winding induction generator. In such a generator, both the power winding (PW) and the control winding (CW) are housed in the stator. This paper presents the performance characteristics of a stand-alone BDFIG operation system. A new T-type steady-state model of a BDFIG is proposed. This model is more suitable for the performance analysis of stand-alone BDFIGs than the conventional Π-type steady-state model and the simplified inner core steady-state model. The characteristics of the power flow and CW current are analyzed by detailed mathematical derivations on the basis of the proposed T-type steady-state model. The analysis results are verified by experiments, which are carried out on a prototype BDFIG. The results of the performance analysis contribute to simplifying the control circuit, improving the control performance, and selecting an appropriate BDFIG for actual industrial applications.

Platysiphon verticillatus and Arcticophycus glacialis: gen. et comb. nov. (Stschapoviales, Phaeophyceae) based on ecological considerations, life history, morphology, and ultrastructure

  • Wilce, Robert T.;Bradley, Peter M.
    • ALGAE
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    • v.34 no.3
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    • pp.199-216
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    • 2019
  • Platysiphon verticillatus and Punctaria glacialis are synonymized by mainly on the basis of shared genes, nine identical sequences. Our hypothesis is that synonymy is erroneous. We posit the many differences of biological features between the two species, their ecological preferences, and occurrences do not support synonymy. Arcticophycus (nov. gen.) is described and contains the new combination Arcticophycus glacialis. Asexual, vegetative, life histories are proposed. Novel reproductive structures are described including previously unknown features of thallus development in the life history of both species. Discovery of the novel Platysiphon cyst, and dual sporangia types in Arcticophycus, is critical in establishing a probable strategy for survival through the Arctic winter for each annual species. Pl. verticillatus is erect, tubular, ovoid to circular in X sections, flaccid, non-parenchymatous, light brown, 10-15 cm high with distinctive photosynthetic hairs in clusters or whorled on the upper one third of the thallus. A. glacialis is erect, planar, robust, parenchymatous, dark brown and hairs absent. The Halosiphon clade is named, consisting of four genera: Halosiphon, Platysiphon, Arcticophycus, and Stschapovia. Occurrence of these genera is identified. Emended are the genus Platysiphon, the family Platysiphonaceae and the order Stschapoviales.

Application of steel-concrete composite pile foundation system as energy storage medium

  • Agibayeva, Aidana;Lee, Deuckhang;Ju, Hyunjin;Zhang, Dichuan;Kim, Jong R.
    • Structural Engineering and Mechanics
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    • v.77 no.6
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    • pp.753-763
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    • 2021
  • Feasibility studies of a reinforced concrete (RC) deep pile foundation system with the compressed air energy storage (CAES) technology were conducted in previous studies. However, those studies showed some technical limitations in its serviceability and durability performances. To overcome such drawbacks of the conventional RC energy pile system, various steel-concrete composite pile foundations are addressed in this study to be utilized as a dual functional system for an energy storage medium and load-resistant foundation. This study conducts finite element analyses to examine the applicability of various composite energy pile foundation systems considering the combined effects of structural loading, soil boundary forces, and internal air pressures induced by the thermos-dynamic cycle of compressed air. On this basis, it was clearly confirmed that the role of inner and outer tubes is essential in terms of reliable storage tank and better constructability of pile, respectively, and the steel tubes in the composite pile foundation can also ensure improved serviceability and durability performances compared to the conventional RC pile system.

Uncertainty quantification of once-through steam generator for nuclear steam supply system using latin hypercube sampling method

  • Lekang Chen ;Chuqi Chen ;Linna Wang ;Wenjie Zeng ;Zhifeng Li
    • Nuclear Engineering and Technology
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    • v.55 no.7
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    • pp.2395-2406
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    • 2023
  • To study the influence of parameter uncertainty in small pressurized water reactor (SPWR) once-through steam generator (OTSG), the nonlinear mathematical model of the SPWR is firstly established. Including the reactor core model, the OTSG model and the pressurizer model. Secondly, a control strategy that both the reactor core coolant average temperature and the secondary-side outlet pressure of the OTSG are constant is adopted. Then, the uncertainty quantification method is established based on Latin hypercube sampling and statistical method. On this basis, the quantitative platform for parameter uncertainty of the OTSG is developed. Finally, taking the uncertainty in primary-side flowrate of the OTSG as an example, the platform application work is carried out under the variable load in SPWR and step disturbance of secondary-side flowrate of the OTSG. The results show that the maximum uncertainty in the critical output parameters is acceptable for SPWR.

Questionnaire Survey on the Proposed Amendments to the Corporate Tax Law in Alignment with the Full Adoption of the International Financial Reporting Standards in Korea (국제회계기준 도입에 따른 법인세법 개정방향 -재정부 발표 개정안에 대한 세무사 대상 설문조사-)

  • Jang, Ji-Kyung
    • The Journal of the Korea Contents Association
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    • v.10 no.10
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    • pp.334-350
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    • 2010
  • This study aims at investigating the possible effects on the tax accounting practices stemming from adopting the IFRS in financial reporting process. It also seeks for policy implications to help alleviate practical conflicts likely to arise from the inconsistencies between the existing tax law and the tax related IFRS provisions. The results of the survey analysis are summarized as follows: firstly, majority opinion is opposed to the fair value based revaluation of property assets as well as the application of immediate recognition of foreign currency translation gains/losses. It favors the existing provision on asset securitization which adopts sales transaction view. Secondly, most of the respondents oppose the proposed amendments which allows dual classification of lease contracts on the ground. Third, functional currency appears acceptable on a conceptual level, even though a deep concern is expressed regarding the practical feasibility of computing taxable income using financial statements translated on the basis of functional currency on a practical viewpoint. Fourth, many respondents support the existing convention of recognizing depreciation expenses for taxation purposes and are in favor of the separation of accounting and tax books on a long-term basis. Fifth, the majority opinion approves the maintenance of existing tax reconciliation system and the recognition of expenses related with the doubtful accounts on reporting basis. Finally, a concern is raised with regard to the added burden of practical job loads needed to comply with the proposed amendments.