• Biomolecules & Therapeutics
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• v.22 no.6
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• pp.547-552
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• 2014

Ribes fasciculatum var. chinense MAX. (R. fasciculatum) has traditionally been used in Korea to treat inflammatory diseases. However, the exact mechanism that accounts for the anti-inflammatory effect of R. fasciculatum is not completely understood. We aimed to ascertain the pharmacological effects of R. fasciculatum on both compound 48/80- or histamine-induced scratching behaviors and 2, 4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis (AD) in mice. Additionally, to find a possible explanation for the anti-inflammatory effects of R. fasciculatum, we evaluated the effects of R. fasciculatum on the production of inflammatory mediators in LPS-stimulated macrophage cells. Treatment of R. fasciculatum significantly reduced compound 48/80- or histamine-induced the pruritus in mice. R. fasciculatum attenuated the AD symptoms such as eczematous, erythema and dryness and serum IgE levels in AD model. Additionally, R. fasciculatum inhibited the production of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and interleukin-6 (IL-6). The maximal rates of TNF-${\alpha}$ and IL-6 inhibition by R. fasciculatum (1 mg/ml) were approximately 32.12% and 46.24%, respectively. We also showed that R. fasciculatum inhibited the activation of nuclear factor-kappa B in LPS-stimulated macrophages. Collectively, the findings of this study provide us with novel insights into the pharmacological actions of R. fasciculatum as a potential molecule for use in the treatment of allergic inflammatory diseases.

• Journal of Fashion Business
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• v.12 no.1
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• pp.76-92
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• 2008

The purpose of this study was to analyze the general wearing attitude & brand Image Perception for Golf Wear in wearer's mind, and to investigate the brand preference on the image characteristics of golf wear, and to find out the wearer's purchasing point for golf wear, for developing the possibility and strategy of the golf wear market for the apparel marketers and manufacturers. For this study, the data obtained from 210 respondents were analyzed by the descriptive statistics, Pearson's simple correlation, Crossing Analysis, parato graph. The results from the study were as follow : The respondents who were specially wearing for golf game were 23.3%(49 persons) among the 210 respondents. The 210 respondents evaluated highly the features of golf wear, such as design(51%), quality(44.3%), materials(36.2%), color(35.2%), size(21.0%), as the purchasing point for golf shirts, otherwise, the 210 respondents evaluated lowly the social aspects of golf wear, such as, fashion conformity, brand loyalty and promotion. And the most important material features for the golf wear was the elasticity, speed dryness by the 210 respondents The most frequent brand by 207 respondents described in the free style was Daks(11.1%) and Ping(11.1%). The 205 respondents described in the free style evaluated Daks(14.6%) as the most preference brand. The reason for the most preference brand was based with the comfort and pleasure of design, quality, color, size, materials.

• Korean Journal of Food Science and Technology
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• v.30 no.4
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• pp.721-727
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• 1998

An analytical method for simultaneous and rapid determination of organophosphorus, organochlorine, carbamate, and pyrethroid pesticides in polished rice was developed. The analysis is performed by gas chromatograph with mass selective detector (GC/MSD) in selected ion monitoring (SIM) mode. Pesticides were extracted from samples with acetone by automated Soxhlet apparatus and this extract was evaporated to dryness for the analysis. The residue was dissolved in hexane, followed by a treatment with a Sep-Pak florisil catridge. Pesticides were positively confirmed by GC/MS, retention times, and ion ratios. This analytical method allows a rapid, reliable, and a good recovery of hydrophilic pesticides. Except far captafol, captan, dichlofluanid and dichlorvos, recoveries of 42 pesticides were over 70%.

• Journal of the Korean Association of Geographic Information Studies
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• v.12 no.4
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• pp.84-94
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• 2009

Moisture Index time series derived from NOAA/AVHRR data have showed to be useful for humid and arid states. The humid/arid states of the Geum river basin are classified by means of the moisture index estimated from the climatic water budget model. Validations showed that the moisture index has excellent ability to detect humid/arid conditions and to measure time of its onset, intensity and duration. In this study, a simple method to classify the moisture index is proposed by statistical distribution condition. Also, the moisture index is compared with the regional actual state to detect drought area.

• Women's Health Nursing
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• v.20 no.1
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• pp.72-82
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• 2014

Purpose: This study was conducted to investigate sexual behaviors and influencing factors affecting premenopausal women who have breast cancer and have undergone surgery. Methods: Seventy premenopausal women, ranging between 35~55 years of age, were included in this study. Sexual behaviors were evaluated using the WSBQ-F (Wilmoth Sexual Behaviors Questionnaire-Female). The in-depth interview was analyzed utilizing content analysis. Results: There were no significant differences regarding the type of surgery, age, time of marriage, education level, occupation, chemotherapy, use of Tamoxifen, and radiotherapy in the sexual activities of premenopausal women with breast cancer. However, quality-related information utilizing qualitative in-depth interviews, revealed 3 issues regarding sexual behaviors.. Participants reported physical discomfort such as vaginal dryness, dyspareunia, emotional changes such as decrease in sexual confidence, and interaction-related changes such as mandatory sexual life, sexual intimacy with one's partner, and being more active sexual behaviors. Conclusion: There were complex changes associated with sexual behavior after surgery for women with breast cancer which included various events related to stress regarding sexual behavior. Communication between women with breast cancer, their partners, and medical caregivers has a ability to maximize the sense of sexual wellbeing while minimizing the sexual crises.

• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.3
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• pp.41-65
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• 2014

Objectives: The purpose of this study is to find out the health condition and the etiology in oriental medicine of the high school girls menstrual disorders by Sasang constitution. Methods: The data from the 795 participants were collected using a structured menstrual history questionnaire. Based on the survey responses, we had 97 adolescents with menstrual disorder as the test group and 97 adolescents without menstrual disorder as the control group. The clinical trials subjects were asked to respond to another questionnaire for identifying their constitutional types and respond to the DSOM and undergo Inbody. We identified significant variables for dysmenorrhea from comparison between the test and control group. Results: The DSOM test showed that the scores of qi stagnation, static blood, cold, dampness, phlegm, heart, kidney were significantly higher in dysmenorrhea, scant menstruation, menstruation at irregular intervals. For the Sasang constitution, there is a difference on the cause of the outbreak. Soyangin from yin deficiency, dryness and blood deficiency is associated with menstrual disorders. Taeumin from cold, dampness and qi deficiency is associated with menstrual disorders. Soeumin from heart, qi stagnation, static blood and spleen is associated with menstrual disorders. Conclusions: For the Sasang constitution, there is a difference on the cause of the outbreak. The result of a comparison of the test and control groups showed that there's no relevance to the body fat mass and body fat percentage with menstrual irregularities.

• International Neurourology Journal
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• v.22 no.4
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• pp.275-286
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• 2018

Purpose: OnabotulinumtoxinA (BoNT-A) is a promising therapy for treating neurogenic detrusor overactivity (NDO) in individuals with spinal cord injury (SCI). This systematic review and meta-analysis aimed to carry out an in-depth review and to make an objective estimation of the efficacy and safety of BoNT-A on NDO after SCI. Methods: The PubMed, Embase, and Cochrane databases were searched for all relevant articles published from 2001 to 2016 that referred to NDO, SCI, and BoNT-A or botulinum toxin A. All data were recorded in an Excel spreadsheet by 2 individual reviewers. Review Manager version 5.3 was used to carry out the meta-analysis. Results: This analysis included 17 studies involving 1,455 patients. Compared with placebo and baseline, BoNT-A was effective in increasing maximum cystometric capacity, volume at first involuntary detrusor contraction, cystometric bladder capacity (all P<0.00001), compliance (P=0.001), and the number of patients with complete dryness (P=0.0003), and decreasing detrusor pressure, the number of patients with no involuntary detrusor contractions, the maximum flow rate, the incidence of detrusor overactivity (all P<0.00001), and the number of urinary incontinence episodes (P=0.001). There were no statistically significant differences between doses of 200 U and 300 U or between injections into the detrusor and submucosa. There were no life-threatening adverse events. Conclusions: BoNT-A is effective and safe in treating NDO after SCI. There were no statistically significant differences between doses of 200 U and 300 U or between injecting into the detrusor and submucosa. However, more high-quality randomized controlled trials are still needed.

• Design & Manufacturing
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• v.13 no.2
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• pp.37-43
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• 2019

This study conducted a research as to condensation heat transfer friction loss headby using three types of flat micro multi-channel tubes with different processing of micro-fin and number of channels inside the pipes and different sizes of appearances. In addition, identical studies were conducted by using smoothing circular tubes with 5mm external diameter to study heat enhancement factor and pressure drop penalty factor. 1) The friction head loss showed an increase as the vapor quality and mass flux increased. In case of saturation temperature, it shows an increase as it gets lower. These factors are the reason occurring as the lower the saturation temperature is, the higher the density of refrigerant vapor gets. The influence of heat flux is similar as the dryness is low, but as it gets higher, it lowers in heat flux, and as the high temperature of high heat flux, it is a factor that occurs as the density gets lower. 2) RMS error of the in case of friction head loss, it showed to be predicted as 0.45~0.67 by Chisholm, Friedel, Lockhart and Martinelli. 3) As forfriction head loss penalty factor, the smaller the aspect ratio is, the larger the penalty factor gets, and as for the effect of micro-fin, the penalty factor increased because it decreases to the gas fluid the way groove for the refrigerant's flow.

• Journal of the Korea Convergence Society
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• v.10 no.3
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• pp.237-242
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• 2019

This study examined the effect of paraffin wax mask pack on skin improvement. The subjects were 13 males and females in 20s. Subjects applied the paraffin wax mask pack eight times for four weeks. To determine the effects of paraffin wax mask pack on the skin, we measured oil, moisture, skin surface temperature, softness of skin and satisfaction in subjective skin condition. After using the paraffin wax mask pack, the moisture, oil content of the facial skin, skin surface temperature and softness of skin increased. In addition, the subjects were highly satisfied with the improvement in subjective skin conditons such as dryness, oil and skin tone. Therefore, these results suggest that paraffin wax mask pack has beneficial effects on skin improvement and it will have high utility and value as development of skin care devices for skin care.

• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.6
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• pp.396-402
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• 2018

Hataedock (HTD) treatment is a traditional preventive therapy for the fetal toxicosis- the acute allergic disease after childbirth, mainly manifested by a variety of skin allergies such as scab, phlegm. The aim of this study was to investigate the efficacy of HTD treatments for the alleviation of inflammation in Dermatophagoides farinae-induced obese NC/Nga mice. 20 mg/kg of Coptidis Rhizoma, Glycyrrhizae Radix (CRGR) extracts as a remedy of HTD treatments were orally administered to NC/Nga mice. We induced obesity in the mice by high-fat diet. To induce skin allergies, the extracts of Dermatophagoides farinae were topically applied on the NC/Nga mice at 4th-6th and 8th-10th weeks. Structural and molecular changes in the skin tissues were measured by immunohistochemical staining. HTD treatment decreased the atopic dermatitis (AD)-like symptoms including hemorrhage, erythema, erosion, edema, and dryness. HTD treatment suppressed the mast cell activation confirmed by reduction of $Fc{\varepsilon}RI$, substance P, and serotonin. The expression of several inflammatory mediators including nuclear factor-kappa B ($NF-{\kappa}B$) p65, inducible nitric oxide synthase (iNOS), vascular endothelial growth factors (VEGFs) was also decreased by HTD treatment. HTD treatment suppressed the allergic, inflammatory responses in the skin tissues of the NC/Nga mice by reducing mast cells and down-regulating several inflammatory mediators.