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Radiation Effect on Body Weight and Hematological Changes of Hybrid Mice by Conventional Fraction, Large Abdominal Field Irradiation (고식적 분할조사시 전복부 조사량에 따른 잡종 백서의 체중과 혈액상의 변화에 관한 연구)

  • Lee, Sung-Heon;Shin, Sei-One;Kim, Myung-Se
    • Radiation Oncology Journal
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    • v.3 no.2
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    • pp.153-157
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    • 1985
  • Radiation effect on mammals, especially on hematologic changes, has been studied since discovery of x-ray. Various experimental animals were tried for radiobiological studies. 72hybrid mice with conventional faction $(15\times/week)$, large abdominal field $12\times3cm$, from symphysis pubic to xyphoid process) were used. Body weight was declined gradually by increasing irradiation doses, nadir was about $29.7\%$ in male; $30.4\%$ in female at 6000 rad irradiation group. Hemoglobin value was nearly normal throughout entire treatment. Significant dropping of WBC count was noted to $40-50\%$ of pretreatment values by only 1000rad irradiation. Change of differential count was interesting; : lymphocyte proportion showed gradual reduction, instead of gradual increasing of segmented neutrophil. Those proportion were reversed after 6000 rad irradiation. Urinary protein tests showed + - +++, showing no correlation with dosage. Application of our study in clinical combination therapy (radiation + chemotherapy) was discussed.

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Design of Solar Tracking CanSat (태양위치추적 캔위성의 개발)

  • Jung, In-Jee;Moon, Ji-Hwan;Kim, Min-Soo;Lim, Byoung-Duk
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.41 no.4
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    • pp.327-334
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    • 2013
  • In August 2012 the first CanSat competition was hosted by the Satellite Research Center of KAIST under auspice of the Ministry of Education, Science and Technology. The present authors team won the first prize in the university session. In this paper the overall procedure of the CanSat project presented from the conceptual design stage to the final launch test. As the compulsory mission CanSat should send GPS data and attitude information to the ground station which in practice was performed via Bluetooth channel. In addition our CanSat is designed to trace the sun for the solar panels supplying electric power of satellite. IMU and servo motors are used for the attitude control in order that the solar sensor of the CanSat is always direct towards the sun. Launching of CanSat was simulated by dropping from a balloon at the height of around 150m via parachute. Launching test results showed that the attitude control of the CanSat and its solar sensing function were successful.

A Intra-media Synchronization Scheme using Media Scaling (서비스 품질 저하 기능의 미디어내 동기화 방안)

  • 배시규
    • Journal of Korea Society of Industrial Information Systems
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    • v.4 no.4
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    • pp.1-6
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    • 1999
  • When continuous media are transmitted over the communication networks, asynchrony which can not maintain temporal relationships among packets my occur due to a random transit delay. There exist two types of synchronization schemes ; for guaranteed or non-guaranteed resource networks. The former which applies a resource reservation technique maintains delay characteristics however, the latter supply a best-effort service. In this paper, I propose a intra-media synchronization scheme to transmit continuous media on general networks not guaranteeing a bounded delay time. The scheme controls transmission times of the packets by estimating next delay time with the delay distribution So, the arriving packets my be maintained within a limited delay boundary, and playout will be performed after buffering to smoothen small delay variations. To prevent network congestion and maintain minimum quality of service the transmitter performs media scaling-down by dropping the current packet when informed excessive delay from the receiver.

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Effects of Sedang-hwan on Experimental Diabetic Rats induced by Streptozotocin (세당환(世糖丸)이 Streptozotocin으로 유발된 흰쥐의 실험적 당뇨에 미치는 영향)

  • Bae, Chul-Ho;Soh, Kyeong-Sun;Jeong, Chan-Gil
    • Journal of Pharmacopuncture
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    • v.9 no.1
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    • pp.33-44
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    • 2006
  • Objectives : We performed this study in order to investigate the effects of Sedang-hwan(世糖丸) on the diabetes mellitus. Methods : We injected a vein with 65mg/kg of streptozotocin(STZ) on the rats. And then administered Sedang-hwan; 18.7mg/kg/day to sample groups and observed the weight and glucose level, insulin, C-peptide, triglyceride, albumin, T-protein, BUN(Blood Urea Nitrogen) and creatinine in blood. Results : 1. The sample groups showed a high suppressive effect of weight loss(P=0.002). 2. The sample groups' glucose level showed a effective in lowering level(P=0.001). 3. The sample groups showed a higher insulin level than control groups. 4. The sample groups showed a higher C-peptide level than control groups(P=0.001). 5. The sample groups' triglyceride level showed a effective in lowering level. 6. The sample groups showed a higher HDL-cholesterol level than control groups(P<0.001). 7. The sample groups showed a higher T-protein level than control groups(P=0.04). 8. The sample groups showed a higher albumin level than control groups(P<0.001). 9. The sample groups' creatinine level showed a effective in lowering level(P=0.04). 10. The sample groups' BUN level showed a effective in lowering level(P=0.03). Conclusions : Conclusively, Sedang-hwan was recognized to have decrease effect of serum glucose, triglyceride, creatinine, BUN of the diabetic rats induced by streptozotocin. It was suggested that Sedang-hwan can be used for effective diabetes mellitus medical treatment. It is also required to study further about detailed principles of blood-sugar dropping effect by Sedang-hwan, and recovery by diabetes mellitus.

The Experimental Study on Anti-bacterial Potency of Coptidis rhizoma extract compare with quantity on Staphylococcus aureus (황련의 증량에 따른 전탕액이 Staphylococcus aureus에 미치는 항균효과에 대한 실험적 연구)

  • Seo, Hyeong-Sik
    • Journal of Pharmacopuncture
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    • v.10 no.3
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    • pp.47-52
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    • 2007
  • Objective This experimental study was performed to investigate the effect of Coptidis rhizoma extract compared with quantity on Staphylococcus aureus that induce keratitis. Methods Minimal inhibitory concentration(MIC) was measured by dropping to $50{\mu}l$ according to density Coptidis rhizoma extract(100%, 10%, 1%, 0.1%) compared with quantity(40g, 80g, 160g). Anti-bacterial potency was measured by the size of inhibition zone with change of volume. Results 1. MIC on Staphylococcus aureus in Coptidis rhizoma extract was showed anti-bacterial potency compared with quantity and density in 100% and 10% of all samples(40g, 80g, 160g). 2. MIC on Staphylococcus aureus in Coptidis rhizoma extract(40g, 80g, 160g) was showed anti-bacterial potency compared with quantity all samples($20{\mu}l,\;30{\mu}l,\;40{\mu}l,\;50{\mu}l$) in 100% density. 3. MIC on Staphylococcus aureus in Coptidis rhizoma extract(40g, 80g, 160g) was showed anti-bacterial potency compared with quantity all samples ($20{\mu}l,\;30{\mu}l,\;40{\mu}l,\;50{\mu}l$) in 100% density. Anti-bacterial potency of 80g Coptidis rhizoma extract decreased compared with 40g. Anti-bacterial potency of 160g Coptidis rhizoma extract decreased compared with 40g in $20{\mu}l,\;30{\mu}l$. Conclusions Coptidis rhizoma extract was showed anti-bacterial potency compare with quantity and density. In herbal drug, antibacterial potency compare with quantity and density must be studied.

The Experimental Study on the continuous Anti-bacterial Potency of Coptidis rhizoma extract on Cultivation of Staphylococcus species(S. aureus, S. epidermidis) (황련(黃連) 전탕액(煎湯液)이 Staphylococcus species(S.aureus, S.epidermidis)의 배양일에 따른 항균효과의 지속성에 관한 연구)

  • Seo, Hyeong-Sik
    • Journal of Pharmacopuncture
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    • v.10 no.3
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    • pp.71-76
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    • 2007
  • Objectives This experimental study was performed to investigate the continuous anti-bacterial potency of Coptidis rhizoma extract on cultivation of Staphylococcus species(S. aureus, S. epidermidis) that induce eye disease. Methods Minimal inhibitory concentration(MIC) was measured by dropping to $50{\mu}l$ diluted Coptidis rhizoma extract(100%, 10%, 1%, 0.1%) on S. aureus, S. epidermidis that were cultivated from 2 to 6 days. Anti-bacterial potency was measured by the size of inhibition zone with change of volume($20{\mu}l,\;30{\mu}l,\;40{\mu}l,\;50{\mu}l$). Results 1. Anti-bacterial potency of Coptidis rhizoma extract on S. aureus was appeared in 100%, 10% and was the same as anti-bacterial potency of 2 days and 6 days. Anti-bacterial potency with change of volume(100%) was increased in propotion to increase volume on all samples. Anti-bacterial potency with change of volume(10%) was increased in propotion to increase volume on all samples except $20{\mu}l$. Anti-bacterial potency of Coptidis rhizoma extract on S. aureus was appeared continuous. 2. Anti-bacterial potency of Coptidis rhizoma extract on S. epidermidis was appeared in 100%, 10% and was the same as anti-bacterial potency of 2 days and 6 days. Anti-bacterial potency with change of volume(100%) was increased in propotion to increase volume on all samples. Anti-bacterial potency with change of volume(10%) was appeared in $50{\mu}l$. Anti-bacterial potency of Coptidis rhizoma extract on S. epidermidis was appeared continuous. Conclusions Anti-bacterial potency of Coptidis rhizoma extract on cultivation of S. aureus & S. epidermidis was showed continuous.

Wavelet Analysis of Elastic Wave for Wall Thinned High-Pressure Service Pipes (감육을 가지는 고압배관에 대한 탄성파의 Wavelet해석)

  • Kim, Jin-Wook;Ahn, Seok-Hwan;Lee, Si-Yoon;Nam, Ki-Woo;Do, Jae-Yoon
    • Journal of the Korean Institute of Gas
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    • v.9 no.3 s.28
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    • pp.1-8
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    • 2005
  • We studied on the nondestructive evaluation of the elastic wave signals of locally wall thinned straight pipe. Wavelet transform was applied for the time-frequency analysis of waveforms obtained by fracture wave detector due to the dropping steel ball. The time-frequency analysis provides time variation of each frequency component involved in a waveform, which makes it possible to evaluate the shape of local wall thinning at each frequency. In this study, comparison by wavelet transform of the AE signals and monotonic bending tests without internal pressure are conducted on 1.91 inch diameter full-scale carbon steel pipe specimens. As the results of tests, fracture behaviors could be shown by the characteristic of mechanical strength of locally wall thinned pipes and the waveforms could be evaluated for the integrity insurance of the piping system according to the length and depth range of the deffeted shape pipes in the real field.

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A Study of UMTS-WLAN Interworking Architecture for Guaranteeing QoS (QoS 보장을 위한 UMTS와 WLAN의 인터워킹 구조)

  • Kim, Hyo-Jin;Yu, Su-Jung;Lee, Jung-Kap;Song, Joo-Seok
    • The KIPS Transactions:PartC
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    • v.13C no.5 s.108
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    • pp.607-612
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    • 2006
  • Universal Mobile Telecommunications System (UMTS) and Wireless Local Area Network (WLAN) have been developed independently. Then, many researchers have studied UMTS-WLAN interworking architecture for the efficiency. However, the transmission capacity difference of two networks causes the transmission quality degradation. Therefore, this paper proposes a UMTS-WLAN interworking architecture for Quality of Service (QoS). The proposed architecture is based on tight coupling and dynamically guarantees QoS by the mobility prediction method. The proposed architecture is simulated by ns-2. Performance experimental results show that the proposed architecture reduces the handover dropping probability comparing with the existing method and enhances the amount of receiving packets comparing with the method without guaranteeing QoS.

A Study on the Ship's Performance of T.S. HANBADA(II) - The Evaluation of Boarding Comfort with Vertical Acceleration - (실습선 한바다호의 운항성능에 관한 연구(II) - 상하가속도를 이용한 승선감 평가 -)

  • Jung, Chang-Hyun;Lee, Yun-Sok
    • Journal of Navigation and Port Research
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    • v.32 no.5
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    • pp.333-339
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    • 2008
  • When a vessel is underway in a heavy weather, passengers and crew suffer from seasickness caused by ship motions such as pitch, heave or roll, or all combined Sickness induces drowsiness, dizziness, headache, stomachache etc, in extreme conditions, they are met with a serious trouble which is physiologically unrecoverable. It results in weakening of spiritual activities or making errors from decrease of motivation, dropping off skills, poor recognition and poor judgement. In this paper, it was examined the international standards concerning the occurrence of sickness and the execution of works, also evaluated the boarding comfort by conducting several times of questionnaire on cadets boarding on the training ship HANBADA As a result, it was confirmed that the main factor of occurring the sickness was the vertical acceleration and the level was more than 0.2g. Also, it was presented the way how to reduce the sickness by changing the speed and/or course in relation to the encounter period.

The Effect of GaAlAs Laser Irradiation on VEGF Expression in Muscle Contusion of Rats (GaAlAs 레이저 조사가 근타박상이 유발된 흰쥐 골격근내 혈관내피성장인자 발현에 미치는 영향)

  • Kim Souk-Boum;Kim Jin-Sang
    • The Journal of Korean Physical Therapy
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    • v.15 no.3
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    • pp.16-44
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    • 2003
  • Skeletal muscle regeneration is a vital process for various muscle myopathies and muscular adaptation to physiological overload. Angiogenesis is the key event in the process of muscle regeneration, and vascular endothelial growth factor(VEGF) plays an important role in it. The purpose of this study was to evaluate the effect of GaAlAs(830nm) laser and immunoreactivity of VEGF on angiogenesis after muscle contusion injury. Muscle contusion injury was induced in the triceps surae muscle by dropping a metal bead(31.4g). GaAlAs laser irradiation(power 20 mW, frequency 2000 Hz, treatment time 15 min) was applied directly to the skin of injured muscle daily for seven days. The experimental group I was irradiated immediately by laser after injury, whereas the experimental group II was irradiated after 1 day of injury. The control group was non-irradiated. The results of this study were as follows. 1. In morphological observation, there were no significant changes in experimental and control groups for 7 days. At 3 days, however, the splited muscle fibers were observed in experimental groups, and the muscle atrophy and granular tissue viewed at 7 days in control group. 2. The VEGF was expressed in muscle fiber that located in the interspace between gastrocnemius and soleus muscles. As the time coursed, the immunoreactivity of VEGF also seemed to be strong in the individual muscle fibers. 3. The experimental group I & II showed higher immunoreactivity of VEGF than control group(p<0.05). Then, the experimental group I showed higher than group II especially(p<0.05). These data suggest GaAlAs semiconduct diode laser irradiation(830nm) enhanced angiogenesis in the skeletal muscle induced contusion injury, and immediate laser irradiation after injury promoted the angiogenesis greatly than after 1 day of injury.

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