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Sharing Pathological Mechanisms of Insomnia and Osteoporosis, and a New Perspective on Safe Drug Choice

  • Yi, Sun Shin;Chung, Soo-Ho;Kim, Pan Soo
    • Journal of Menopausal Medicine
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    • v.24 no.3
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    • pp.143-149
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    • 2018
  • Lack of adequate sleep has become increasingly common in our 24/7 modern society. Reduced sleep has significant health consequences including metabolic and cardiovascular disorders, and mental problems including depression. In addition, although the increase in life expectancy has provided a dream of longevity to humans, the occurrence of osteoporosis is a big obstacle to this dream for both male and female. It is known that insomnia and bone health problems, which are very critical conditions in human life, interestingly, share a lot of pathogenesis in recent decades. Nevertheless, due to another side effects of the synthetic drugs being taken for the treatment of insomnia and osteoporosis, patients have substantial anxiety for the safety of drugs with therapeutic expectation. This review examines the pathogenesis shared by sleep and osteoporosis together and herbal medicine, which has recently been shown to be safe and efficacious in the treatment of both diseases other than synthetic drugs. We suggestions for how to treat osteoporosis. These efforts will be the first step toward enabling patients to have comfortable and safe prescriptions through a wide selection of therapeutic agents in the future.

Roland Giguère and Poetic Landscape - La main au feu (롤랑 지게르와 시의 풍경 - 『불 위의 손』을 중심으로)

  • Kim, Yong Hyun
    • Cross-Cultural Studies
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    • v.39
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    • pp.153-176
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    • 2015
  • Poet, painter and publisher, Roland $Gigu{\grave{e}}re$ is one of Quebec's outstanding figures, inspired by both Surrealism and Quebec nationalism. He participated in contemporary artistic movement 'Phases' and influenced collective self-awareness and political ferment, 'Quiet Revolution'. In La Main au feu(1973), his poetry represent a landscape dominated by darkness in contrast with red color of fire from the volcanic crater. The world is immersed in darkness of despair which allude to the Great Darkness of Quebec society. Acts of violence assume many different forms: crows, black rain, dark flow, frenzy of knife blows. Both things and humans are in the state of absence or lack. Life falls into opacity of death. In the background of dark landscape, we discover Miror, a singular character. Similar to chain of mountains and to bare forest, he is a creature that shape the tragic inner world of poet. He is as like as seismograph that record the tremble of being. Finally, in order to fight the darkness of environment, the poet attempt to use the power of fire of volcanoes. The flow of magma become paintings of his dream and the flame of eruption, poetry of cry toward the sky. 'La main au feu' means the will to resist injustice and repression in the world. The tragic reality is replaced by a dream that become second reality out of reach of the force of hostile external circumstances.

"A Very Sudden Thing": Recapturing Cold War History in Philip Roth's American Pastoral

  • Lew, Seunggu
    • English & American cultural studies
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    • v.10 no.2
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    • pp.49-72
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    • 2010
  • As the first of Philip Roth's recent series of novels that delve into American Cold War history deeply entwined with the post-war Jewish American experience, American Pastoral traces the tragic fall of a third-generation Jewish American named Seymour "Swede" Levov, whose dream of complete assimilation to the post-ethnic American paradise is irrecoverably disrupted when his young daughter blows up the local post office to protest against the Vietnam War. This essay proposes to examine Swede Levov's interrupted pursuit of the American dream by locating it within specific Cold War contexts and national imaginaries propagated particularly during the years from John F. Kennedy to Lyndon B. Johnson. In so doing, I will argue that Roth presents a paradoxical vision of Jewish American identity that could be acquired by performing perpetual self-effacement and submergence into the non-place of anonymity and doubleness, a mythic location of the post-ethnic Cold War American family. Levov's life becomes true part of the mythic narrative of American history when he realizes that his life, just like the nation's history, is a series of temporalities radically discontinued without any manageable detour ot divine bypass to cross over. Rather than indicating Roth's retraction from the postmodern understanding of subjectivity, the novel's historical realism, I will argue, serves to illuminate the postmodern conditions of American Cold War history and ethnic identity.

군 장병의 개인특성과 기업가정신이 창업의지에 미치는 영향에 대한 연구 : 군 창업동아리 활동을 중심으로

  • Jo, In-A;Kim, Jong-Seong
    • 한국벤처창업학회:학술대회논문집
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    • 2020.11a
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    • pp.157-161
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    • 2020
  • 최근 우리 사회는 코로나 19(COVID 19)와 4차 산업혁명으로 인한 노동시장의 불안과 더불어 매년 증가하고 있는 청년실업의 해결책으로 청년창업에 관심이 집중되고 있고, 창업지원 정책 또한 다양하게 시행하고 있다. 이와 관련 군에서도 일과 후 자기 개발을 통한 생산적 군 복무로 부대 전투력 극대화와 개인의 경력 단절 최소화를 위한 일환으로 2018년 부터 '청년 Dream, 국군 드림' 이라는 역점 사업을 추진 중에 있다. Dream의 알파벳중 'Ⓡ 창·취업 기회 제공(Raising Job Opportunities)'의 경우 2020년 3월 기준 육군은 약 870여개의 창업동아리를 운영하고 있다. 하지만 군부대의 특성상 전투임무 수행에 우선순위가 있다보니 창업동아리를 능동적으로 운영하기에는 여러 가지 제약사항이 있으며, 군 창업동아리와 관련된 선행연구 또한 미천한 수준에 머무르고 있다. 본 연구의 목적은 군 창업동아리 활동 장병 200명을 대상으로 '군 장병의 개인 특성(성취욕구, 자기효능감, 동기부여)과 기업가정신(혁신성, 진취성, 위험감수성)이 창업의지에 미치는 영향'을 분석해 보는데 있다. 이를 통해 군 장병을 대상으로 하는 군 창업동아리 활동이 지속적으로 운영 될 수 있는 방안을 모색해 보고, 실질적인 교육지원 방향을 제시하는 등 군 조직 역량 강화와 개인 발전, 그리고 군 창업동아리 활성화 방안에 대해 논의해 보고자 한다.

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Effects of Plant Growth Regulators for In Vitro Propagation of Cannabis sativa varieties (대마 품종별 기내 증식을 위한 식물생장조절제 처리 효과)

  • Hyunseok Lee
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2022.09a
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    • pp.124-124
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    • 2022
  • 대마(Cannabis sativa)는 카나비노이드(cannabinoids) 계열의 성분으로 인한 약리효능 뿐만 아니라 섬유, 식품 등의 분야에서도 식물소재로 활용도가 높은 것으로 알려져 있다. 최근 의료용 대마의 경우 규제완화가 예정됨에 따라 관련 산업분야에서도 안정적 원료 소재 생산에 대한 연구가 요구되고 있다. 대마는 실생번식이 가능한 종이나, 의료용 등 소재의 안정적 공급을 위해서는 균일한 cannabidiol(CBD) 성분의 확보가 가능한 영양증식 방법이 대안으로 사용될 수 있다. 따라서 본 연구에서는 영양증식 방법 중 조직배양 기술을 이용한 대마 품종별(Cherry Blossom, Queen Dream과 Hot Blonde) 증식법 구명을 위하여 식물생장조절제의 종류 및 농도에 따른 기내생육특성을 조사하였다. 세 품종 모두 1 mg l-1 thidiazuron (TDZ) 단독처리 시 신초(> 2cm)가 가장 많이 유도되었다. 단 Queen Dream 품종은 0.5 mg l-1 와 TDZ 0.2 mg l-1 NAA 혼용처리구에서 많은 수의 신초가 유도되었으나 상대적으로 신초의 길이(< 2cm)는 짧은 것으로 확인할 수 있었다. 발생된 신초는 MS 기본배지에서 발근을 유도한 후 토양에 순화하여 정상적인 식물체로 발달되었다. 이와 같은 식물생장조절제 처리를 포함한 식물조직배양 방법은 유용 개체·품종의 증식 및 의료·산업용 원료 소재의 안정적 생산에 활용될 수 있다.

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Automatic Poster Generation System Using Protagonist Face Analysis

  • Yeonhwi You;Sungjung Yong;Hyogyeong Park;Seoyoung Lee;Il-Young Moon
    • Journal of information and communication convergence engineering
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    • v.21 no.4
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    • pp.287-293
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    • 2023
  • With the rapid development of domestic and international over-the-top markets, a large amount of video content is being created. As the volume of video content increases, consumers tend to increasingly check data concerning the videos before watching them. To address this demand, video summaries in the form of plot descriptions, thumbnails, posters, and other formats are provided to consumers. This study proposes an approach that automatically generates posters to effectively convey video content while reducing the cost of video summarization. In the automatic generation of posters, face recognition and clustering are used to gather and classify character data, and keyframes from the video are extracted to learn the overall atmosphere of the video. This study used the facial data of the characters and keyframes as training data and employed technologies such as DreamBooth, a text-to-image generation model, to automatically generate video posters. This process significantly reduces the time and cost of video-poster production.

A Study on the Interpersonal Relationship between Parenting Stress and Children's Problem Behavior in Low Income Families (저소득층 가정 양육자의 양육스트레스와 아동 문제행동 간의 상호인과적 관계에 대한 종단연구)

  • Song, Mi-Ryoung;Hong, Seung-ae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.6
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    • pp.340-348
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    • 2020
  • The purpose of this study was to investigate the mutual relationship between parenting stress and children's problem behaviors among those participating in dream start services. In order to verify the effect of parental and child effects on child's problem behavior and parenting stress based on repeated measures from the first grade of elementary school to the third grade of elementary school among children participating in dream start services, autoregressive cross-lagged modeling was applied. As a result, the stability coefficient showed that the two variables were significantly stable for 3 years. In other words, the measurement was maintained at a similar level with time. The causal relationship between parents 'parenting stress and child' s problem behavior was generally explained by the parental effect. In other words, parental stress is related to the child's problem behavior. These results show that the economic stress of poverty increases parents' parenting stress, which can negatively affect the adaptive development of children in the process of raising children.

Effects of Proprioceptive Neuromuscular Facilitation Program Combined with Dynamic Neuromuscular Stabilization Approach on Balance in Patient with Cerebellum Atrophy -Case Report- (동적 신경근 안정화 접근법과 결합한 PNF 중재 프로그램이 소뇌 위축 환자의 균형에 미치는 영향 -사례보고-)

  • Na, Eun-Jin;Moon, Sang-Hyun;Kim, Eun-Kyung;Park, Du-Jin
    • PNF and Movement
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    • v.14 no.3
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    • pp.237-244
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    • 2016
  • Purpose: This case report examines the influence of proprioceptive neuromuscular facilitation (PNF) combined with a dynamic neuromuscular stabilization approach on balance in patients with cerebellar atrophy. Methods: The target subject of this case report was a 34-year-old woman who was informed of the purpose of this research and voluntarily agreed to participate in it. The case report conformed to research ethics based on the Helsinki Declaration. The target subject was confirmed to have cerebellar atrophy from an unknown cause in 2009 and was diagnosed with slight ataxia. At that time, she could carry out daily activities without physical therapy. On May 19, 2015, she suffered both a subdural hemorrhage (SDH) and subarachnoid hemorrhage (SAH) in a traffic accident. She was urgently moved to the emergency room and managed by nonsurgical treatment, and then, the cerebellar atrophy and ataxia gradually deteriorated. To evaluate the patient's balance capacity before and after intervention, the trunk impairment scale (TIS), trunk impairment scale (OLST) during eye-closing/opening, timed up and go test (TUG), and visual analogue scale (VAS) were conducted. The PNF intervention program was executed for 30 min, four times a week, for three weeks. Results: The TIS and OLST during eye-closing/opening were improved by as much as a point, by 8.15 s and 6.21 s, respectively, after applying the PNF program. TUG and VAS decreased by 1.33 s and 3 points, respectively, after intervention. According to the result, the OLST during eye-closing/opening and VAS improved remarkably in comparison with those before intervention. Conclusion: As the final result of the case report, PNF intervention combined with DNSA more effectively improved the static balance capacity, such as the OLST during eye-closing/opening and VAS, compared to the dynamic balance capacity. In addition, the intervention duration and period of the exercise program are recommended to be more than 1 h a day for four weeks considering the learning ability of a patient with cerebellar atrophy.

Systematic Review on the Sasang Type-specific Pathophysiological Symptoms of Sleep (사상체질별 수면 소증(素證)에 대한 체계적 고찰연구)

  • Lee, Han Byul;Han, Yoo Ri;Han, Sang Yun;Kim, Yun Im;Son, Kyungwoo;Lee, Mi Suk;Lim, Jung Hwa;Chae, Han
    • Journal of Oriental Neuropsychiatry
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    • v.26 no.4
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    • pp.337-348
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    • 2015
  • Objectives: The purpose of this study was to review previous clinical studies on underlying mechanisms of sleep-related type-specific pathophysiological symptoms among the Sasang types. Methods and Procedure: We reviewed seven research databases from December 2003 to August 2015 with the keywords Sasang typology, constitution and sleep. The Sasang type-specific sleep-related symptoms were analyzed based on seven categories, including subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleep medications and daytime dysfunction. Results: Total of twelve studies were included in the analysis. The Tae-Yang type showed low subjective sleep quality, long sleep latency and frequent awakening, and the So-Yang type showed long sleep latency. The Tae-Eum type presented high subjective sleep quality, short sleep duration, frequent snore, toss and turn during the sleep, and insomnia and low frequency of dream. The So-Eum type showed long sleep latency in male and high frequency of dream. The Eum type combining Tae-Eum and So-Eum types had higher subjective sleep quality, longer sleep duration and higher frequency of dream than the Yang type combining Tae-Yang and So-Yang types.Conclusions This study reviewed type-specific sleep-related characteristics and discussed possible pathophysiological mechanisms involved. Differences in sleep characteristics among the Sasang types might stem from type-specific temperaments and require further study.

Development of the Balanced Language Education Program Model -on the basis of young children in low-income families participating in Dream Start- (균형적 언어교육 프로그램 모형 개발 -드림스타트 저소득 가정 유아를 대상으로-)

  • Kim, You-Hwa;Kwak, Young-suk
    • The Journal of the Korea Contents Association
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    • v.16 no.12
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    • pp.600-621
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    • 2016
  • This study aims to develop and apply the language education program model - based on balanced language education approach - on development of literacy of young children in low-income families, specially participating in Dream Start public welfare service. Development of this languge education program was based on the basic view and characteristis of balanced language education. It was progressed in accordance with Analyze-Design-Develop-implement-Evaluate(ADDIE), which is an widely-used instructional design model. Educational contents including reading skills of picture books based on whole language approach and well-structured reading and writing sequences, teaching and learning method including the principles and the strategies and teaching and learning systematic evaluation method are proposed in viewpoint of balanced language teaching approach. The application of the program was conducted targeting 20 young children participating in Dream Start welfare service from June 2015 until early November. To evaluate the effectiveness of this program, word reading inspection and nonsense word reading inspection developed by Ko, Yeon-Kyung(2002) were performed. The reflective thinking journal of visiting teachers and the satisfaction reported by parents were analysed in the qualitative research method. As a result, reading skills of young children were improved. The superiority of the program - prefernce for the picture book, interests in written languages, effectiveness of individualized language education method - was demonstrated by qualitative analysis of reflective journal. This study has the significance on presenting the executable language education model for literacy development of young children in low-income families based on balanced language education approach.