• Title/Summary/Keyword: division-by-convergence

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Upregulation of Carbonyl Reductase 1 by Nrf2 as a Potential Therapeutic Intervention for Ischemia/Reperfusion Injury during Liver Transplantation

  • Kwon, Jae Hyun;Lee, Jooyoung;Kim, Jiye;Kirchner, Varvara A.;Jo, Yong Hwa;Miura, Takeshi;Kim, Nayoung;Song, Gi-Won;Hwang, Shin;Lee, Sung-Gyu;Yoon, Young-In;Tak, Eunyoung
    • Molecules and Cells
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    • v.42 no.9
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    • pp.672-685
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    • 2019
  • Currently, liver transplantation is the only available remedy for patients with end-stage liver disease. Conservation of transplanted liver graft is the most important issue as it directly related to patient survival. Carbonyl reductase 1 (CBR1) protects cells against oxidative stress and cell death by inactivating cellular membrane-derived lipid aldehydes. Ischemia-reperfusion (I/R) injury during living-donor liver transplantation is known to form reactive oxygen species. Thus, the objective of this study was to investigate whether CBR1 transcription might be increased during liver I/R injury and whether such increase might protect liver against I/R injury. Our results revealed that transcription factor Nrf2 could induce CBR1 transcription in liver of mice during I/R. Pre-treatment with sulforaphane, an activator of Nrf2, increased CBR1 expression, decreased liver enzymes such as aspartate aminotransferase and alanine transaminase, and reduced I/R-related pathological changes. Using oxygen-glucose deprivation and recovery model of human normal liver cell line, it was found that oxidative stress markers and lipid peroxidation products were significantly lowered in cells overexpressing CBR1. Conversely, CBR1 knockdown cells expressed elevated levels of oxidative stress proteins compared to the parental cell line. We also observed that Nrf2 and CBR1 were overexpressed during liver transplantation in clinical samples. These results suggest that CBR1 expression during liver I/R injury is regulated by transcription factor Nrf2. In addition, CBR1 can reduce free radicals and prevent lipid peroxidation. Taken together, CBR1 induction might be a therapeutic strategy for relieving liver I/R injury during liver transplantation.

The Role of Innovative Energy Public Firms' Channels according to Shale Gas for E-Convergence Economy.

  • Seo, Dae-Sung;Kim, Seung-Ryeol
    • Journal of Distribution Science
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    • v.14 no.5
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    • pp.17-26
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    • 2016
  • Purpose - The E-convergence economy is requested with the economic change of the diverse energy supplies, according to the exploits of Shale gas. By analyzing the electric energy supply and demand in accordance with the various cases, it has proved indirectly to create a convergence economy. Research design, data, and methodology - The research design would make realize its potential change with which government or companies have focused on the energy objection between Shale gas and Electric vehicles. Results - The paper suggests that Shale gas has expanded with the emphasis on the Electrical convergence economy or EVs. Due to these results, they also show why it should not be delayed in the development of shale gas and electric vehicles at the same time. Conclusions - All this is from the reason of opening the E-convergence economy over time. It is required that Korea should prepare E-convergence economy. Public regional energy should be present through the consistent selection of development for energy linking E-economy and E-trans distribution.

A Study on Establishment of the IoT-Based Remote Management System for District Heating Facilities (지역난방설비를 위한 IoT 기반 원격 관리 시스템 구축에 대한 연구)

  • Kim, Jun-hyeok;Lee, Sang-hak;Kim, Byung-min
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.42 no.3
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    • pp.698-701
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    • 2017
  • The district heating system supports currently 1.3 million of houses in South Korea, and it is composed of two main parts: provision and distribution. For the provision part, Korea District Heating Corporation supervises the system with proper devices and experts, whereas for the distribution parts, there is no main supervision system and it depends highly on experts although it is very difficult to find the proper experts. In this paper, we consider IoT based remote management system for district heating distribution to properly supervise heating distribution by experts and/or programs remotely.

Control strategies of energy storage limiting intermittent output of solar power generation: Planning and evaluation for participation in electricity market

  • Sewan Heo;Jinsoo Han;Wan-Ki Park
    • ETRI Journal
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    • v.45 no.4
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    • pp.636-649
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    • 2023
  • Renewable energy generation cannot be consistently predicted or controlled. Therefore, it is currently not widely used in the electricity market, which requires dependable production. In this study, reliability- and variance-based controls of energy storage strategies are proposed to utilize renewable energy as a steady contributor to the electricity market. For reliability-based control, photovoltaic (PV) generation is assumed to be registered in the power generation plan. PV generation yields a reliable output using energy storage units to compensate for PV prediction errors. We also propose a runtime state-ofcharge management method for sustainable operations. With variance-based controls, changes in rapid power generation are limited through ramp rate control. This study introduces new reliability and variance indices as indicators for evaluating these strategies. The reliability index quantifies the degree to which the actual generation realizes the plan, and the variance index quantifies the degree of power change. The two strategies are verified based on simulations and experiments. The reliability index improved by 3.1 times on average over 21 days at a real power plant.

Electromechanical Properties of Conductive MWCNT Film Deposited on Flexible Substrate Affected by Concentration of Dispersing Agent (분산제 농도에 따른 MWCNT 전도성 유연필름의 전기-기계적 특성)

  • HwangBo, Yun;Kang, Yong-Pil;Kim, Jae-Hyun;Kim, Duck-Jong;Lee, Hak-Joo
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.5
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    • pp.517-521
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    • 2012
  • Carbon nanotubes (CNTs) have been regarded as a promising material for the fabrication of flexible conductors such as transparent electrodes, flexible heaters, and transparent speakers. In this study, a multiwalled carbon nanotube (MWCNT) film was deposited on a polyethylene terephthalate (PET) substrate using a spraying technique. MWCNTs were dispersed in water using sodium dodecyl sulfate (SDS). To evaluate the effect of the weight ratio between SDS and MWCNTs on the electromechanical properties of the film, direct tensile tests and optical strain measurement were conducted. It was found that the CNT film hardly affected the mechanical behavior of CNT/PET composite films, while the electrical behavior of the CNT film was strongly affected by the SDS concentration in the CNT film. The electrical resistance of CNT/PET films gradually increased with the strain applied to the PET substrate, even up to a large strain that ruptured the substrate.

Inverted CdSe/ZnS Quantum Dots Light-Emitting Diode Using Low-Work Function Organic Material Polythylenimine Ethoylated

  • Kim, HongHee;Son, DongIck;Jin, ChangKyu;Hwang, DoKyung;Yoo, Tae-Hee;Park, CheolMin;Choi, Won Kook
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.246.1-246.1
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    • 2014
  • Over the past several years, colloidal core/shell type quantum dots lighting-emitting diodes (QDLEDs) have been extensively studied and developed for the future of optoelectronic applications. In the work, we fabricate an inverted CdSe/ZnS quantum dot (QD) based light-emitting diodes (QDLED). In order to reduce work function of indium tin oxide (ITO) electrode for inverted structure, a very thin (<10 nm) polyethylenimine ethoxylated (PEIE) is used as surface modifier[1] instead of conventional metal oxide electron injection layer. The PEIE layer substantially reduces the work function of ITO electrodes which is estimated to be 3.08 eV by ultraviolet photoemission spectroscopy (UPS). From transmission electron microscopy (TEM) study, CdSe/ZnS QDs are uniformly distributed and formed by a monolayer on PEIE layer. In this inverted QDLEDs, blend of poly (9,9-di-n-octyl-fluorene-alt-benzothiadiazolo) and poly(N,N'-bis(4-butylphenyl)-N,N'-bis(phenyl)benzidine] are used as hole transporting layer (HTL) to improve hole transporting property. At the operating voltage of 8 V, the QDLED device emitted spectrally orange color lights with high luminance up to 2450 cd/m2, and showed current efficacy of 0.6 cd/A, respectively.

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Self-Powered Integrated Sensor Module for Monitoring the Real-Time Operation of Rotating Devices (회전기기 실시간 동작상태 모니터링을 위한 자가발전 기반 센서모듈)

  • Kim, Chang Il;Yeo, Seo-Yeong;Park, Buem-Keun;Jeong, Young-Hun;Paik, Jong Hoo
    • Journal of Sensor Science and Technology
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    • v.28 no.5
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    • pp.311-317
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    • 2019
  • Rotating devices are commonly installed in power plants and factories. This study proposes a self-powered sensor node that is powered by converting the vibration energy of a rotating device into electrical energy. The self-powered sensor consists of a piezoelectric harvester for self-power generation, a rectifier circuit to rectify the AC signal, a sensor unit for measuring the vibration frequency, and a circuit to control the light emitting diode (LED) lighting. The frequency of the vibration source was measured using a piezoelectric-cantilever-type vibration frequency sensor. A green LED was illuminated when the measured frequency was within the normal range. The power generated by the piezoelectric harvester was determined, and the LED operation was assessed in terms of the vibration frequency. The piezoelectric harvester was found to generate a power of 3.061 mW or greater at a vibration acceleration of 1.2 g ($1g=9.8m/s^2$) and vibration frequencies between 117 and 123 Hz. Notably, the power generated was 4.099 mW at 122 Hz. As such, our self-powered sensor node can be used as a module for monitoring rotating devices, because it can convert vibration energy into electrical energy when installed on rotating devices such as air compressors.

OGM-Based Real-Time Obstacle Detection and Avoidance Using a Multi-beam Forward Looking Sonar

  • Han-Sol Jin;Hyungjoo Kang;Min-Gyu Kim;Mun-Jik Lee;Ji-Hong Li
    • Journal of Ocean Engineering and Technology
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    • v.38 no.4
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    • pp.187-198
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    • 2024
  • Autonomous underwater vehicles (AUVs) have a limited bandwidth for real-time communication, limiting rapid responses to unexpected obstacles. This study addressed how AUVs can navigate to a target without a pre-existing obstacle map by generating one in real-time and avoiding obstacles. This paper proposes using forward-looking sonar with an occupancy grid map (OGM) for real-time obstacle mapping and a potential field algorithm for avoiding obstacles. The OGM segments the map into grids, updating the obstacle probability of each cell for precise, quick mapping. The potential field algorithm attracts the AUV towards the target and uses repulsive forces from obstacles for path planning, enhancing computational efficiency in a dynamic environment. Experiments were conducted in coastal waters with obstacles to verify the real-time obstacle mapping and avoidance algorithm. Despite the high noise in sonar data, the experimental results confirmed effective obstacle mapping and avoidance. The OGM-based potential field algorithm was computationally efficient, suitable for single-board computers, and demonstrated proper parameter adjustments through two distinct scenarios. The experiments also identified some of challenges, such as dynamic changes in detection rates, propulsion bubbles, and changes in repulsive forces caused by sudden obstacles. An enhanced algorithm to address these issues is currently under development.

Complex Permeability of 0-3 Polymer Magnetic Composites for Near-Field Communication (근역장 통신용 0-3형 고분자 자성 복합소재의 복소투자율 변화)

  • Nam, Joong-Hee;Lim, Choong Hyuck;Yun, Ji Sun;Jeong, Young-Hun;Cho, Jeong-Ho;Paik, Jong Hoo;Kim, Hyo Tae;Kim, Jong-Hee
    • Journal of the Korean Magnetics Society
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    • v.22 no.6
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    • pp.216-220
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    • 2012
  • Magnetic properties of composite materials consisting of polymer filled with ferromagnetic powders (MnZn ferrite, Fe-Si alloy) were investigated in this study. The volume fraction of magnetic powders as fillers was varied from 70 % to 95 %. This paper presents the fabrication method of polymer magnetic composites in an effort to produce the 0-3 types of MnZn ferrite and FeSi as fillers with a proper complex permeability through the optimization of some experimental parameters. The polymer matrix composites were prepared by mixing the crushed ferrites and flaky FeSi powders homogenously with low-density resins (EPDM, epoxy). The relationships among the manufacturing technology of these materials, their filler volume fraction, as well as their complex permeability were measured and analyzed.

The Study on the Improvement of Piezoelectric and Electrical Characteristics of Bi0.5(Na0.78K0.22)0.5TiO3 Ceramics Modified by the La-based ABO3 Pervskite Structure (La 기반의 ABO3 구조를 갖는 첨가물에 따른 Bi0.5(Na0.78K0.22)0.5TiO3의 압전 및 전기적인 특성 향상 연구)

  • Lee, Ku Tak;Park, Jung Soo;Yun, Ji Sun;Cho, Jeong Ho;Jeong, Young Hun;Paik, Jong Hoo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.27 no.11
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    • pp.707-711
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    • 2014
  • The $0.99Bi_{0.5}(Na_{0.78}K_{0.22})_{0.5}TiO_3-0.01LaAlO_3$, $0.01LaMnO_3$ or $0.01LaFeO_3$ (0.99BNKT-0.01LA, 0.01LM or 0.01LF) ceramics were prepared by a conventional mixed mothod. The structure and morphology of the lead free ceramics were characterized by XRD (X-ray diffraction) and FE-SEM (field emission scanning electron microscopy). XRD results indicated that the BNKT ceramics modified by LA, LM or LF induced a transition from a ferroelectric tetragonal to a non-polar pseudo-cubic phase, leading to decrease in the remnant polarization ($P_r$) and coercive field ($E_c$) in the P-E hysterisis loops. The effects of the BNKT ceramics modified by La-based $ABO_3$ pervskite structure on the electric-field induced strain were investigated, and the largest normalized unipolar strain ($S_{max}/E_{max}$) was found in BNKT-0.01LF ceramic.