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Epidemiology and Clinical manifestations of Enterovirus in Pediatric Inpatient in Incheon (인천지역 소아 입원 환자의 엔테로바이러스 역학과 혈청형에 따른 임상양상 비교)

  • Cho, Byoung Wook;Kwon, Seong Eun;Kwon, Mun Ju;Hur, Myong Je;Kim, Kyung Seon;Hong, Young Jin;Kim, Soon Ki;Kwon, Young Se;Kim, Dong Hyun
    • Pediatric Infection and Vaccine
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    • v.23 no.1
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    • pp.46-53
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    • 2016
  • Purpose: Enterovirus (EV) infection in children can manifest various diseases from asymptomatic infection to nonspecific febrile illness, hand-foot-mouth disease, and aseptic meningitis. This study was aimed to investigate epidemiology and clinical significance of various genotypes of EV infections in pediatric inpatient. Methods: We collected the stool samples from the admitted pediatric patients in Inha University Hospital from March 2014 to March 2015. EV detection and genotype identification were performed by real-time RT-PCR and semi-nested RT-PCR. Phylogenetic trees were constructed by neighbor joining method. Results: A total of 400 samples were collected during study period and 112 patients (28%) were diagnosed with EV infections. The mean age of EV positive patients was 2.66 years (0.1-14) and sex ratio was 1.73:1. Genetic sequences of EVs were identified; coxsackievirus B5 (17, 15.2%), coxsackievirus A16 (13, 11.6%), enterovirus 71 (10, 8.9%), and coxsackievirus A2 (9, 8.0%). Nonspecific febrile illness (96, 86%) was the most common clinical manifestation and the duration of fever was 0-11 days (mean 3.1 days). Rash (44, 39%) and meningitis (43, 38%) were followed. Patients who were attending daycare center or had siblings accounted for 82.1%. Phylogenetic relationship tree revealed 6 distinct genogroups among 56 types of EVs. Conclusions: This study is the report of epidemiology, serotype distribution and clinical manifestations of children with EV infection in Incheon. This data will be helpful for further study about the epidemiology of EV infection in Korea.

Epidemiologic study of rotaviral gastroenteritis in Daejeon, Korea, 2001-2005 (대전 지역에서 로타바이러스 위장관염의 역학적 연구(2001-2005년))

  • Chae, Joo-Hee;Kim, Min-Ji;Kim, Do-Hee;Lee, Kyung-Yil;Kang, Jin-Han;Lee, Joon-Sung
    • Pediatric Infection and Vaccine
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    • v.14 no.2
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    • pp.155-161
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    • 2007
  • Purpose : We evaluated the epidemiologic characteristics of rotavirus gastroenteritis in Daejeon, Korea from January 2001 through December 2005. Methods : We retrospectively analyzed 540 medical records of children with gastroenteritis, who had been hospitalized at The Catholic University of Korea, Daejeon St. Mary's Hospital and were tested positive by rotavirus stool examinations (latex agglutination or immunechromatography). Results : The mean age was $21.8{\pm}15.3$ months (ranged from 2 months to 9 years of age) and the distribution of children were 144 cases (26.7%) in <1 year of age, 228 (42.2%) in 1 year of age, and 93 (17.2%) in 2 years of age, and the 505 children (93.5%) were less than 4 years of age. The male-to-female ratio was 1.4:1. The mean annual number of cases was 108, with a relative even occurrence in each year. Although the patients with rotaviral gastroenteritis occurred through the year, a higher rate of occurrence was seen in spring (March to May, 40.8%) and winter season (December to February, 37.9%), without significant differences in each year. Conclusion : In Daejeon, Korea, rotaviral gastroenteritis have occurred in children less than 4 years of age, with slight annual variations and similar seasonal occurrence in the recent years. The data indicate that the recent trend in peak rotavirus activity is different from that observed decades ago in Korea.

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A Study on Estimation of Caring Demand for Extended Care Facilities by Activities of Daily Living (ADL(Activities of Daily Living)을 이용한 무료노인요양시설 수용노인의 돌봄필요도에 관한 연구)

  • Kim, Chul-Woung;Moon, Ok-Ryun;Lee, Sang-Yi;Yoo, Jae-Won;Yi, Sang-Gu
    • Journal of Preventive Medicine and Public Health
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    • v.31 no.3 s.62
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    • pp.564-578
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    • 1998
  • Most extended care facilities have admitted both the healthy and unhealthy elderly, among which members' average caring demand vary. The Aged Welfare Law, however, currently provides no reasonable basis on the staffing policy for extended care facilities. It just reflects the admitted number of the elderly rather than differences in members' average caring demand among facilities. This study is designed to estimate the need for caring staff on the basis of the correlation between the individual health status measured by various tools including Activities of Daily Living and caring demand by actual service time for each one. The sample included all of the admitted elderly(187 persons) in 4 extended care facilities, two in Seoul and the other two in Kangwon-Do over the survey period October 5 through October 20, 1996. The survey process consisted of 3 stages. (1) The current staffing information was collected through self-completed written questionnaires left for head of official in each facility. (2) Six graduate students at School of Public Health interviewed all residents to collect information on their health status and sociodemographics. The response rate for the interview was relatively high(85%). (3) Information on direct and indirect caring time consumed for each residents came from self-completed written questionnaires given to nurses and helpers in each target facilities. Analysis of the data was made using Pearson's correlation and multiple regression technique through SAS program. Based on this procedure, the following was found. 1. No facility meet the staffing standard in the Aged Welfare Law completely. 2. It is actual service time that is most correlated with ADL(Activities of daily living). 3. When all of the elderly are divided by four groups based on the level of ADL, the mean values of needed caring time in each group are 15, 21, 36 and 88 minutes respectively. 4. There is no significant difference among facilities in distribution of elderly person by group. 5. No facility meets the estimated number of nurses and helpers which reflects health status of the admitted elderly. Therefore, it is required that severity of the admitted elderly be considered in establishing staffing standard for extended care facility.

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Business Strategies for Korean Private Security-Guard Companies Utilizing Resource-based Theory and AHP Method (자원기반 이론과 AHP 방법을 활용한 민간 경호경비 기업의 전략 연구)

  • Kim, Heung-Ki;Lee, Jong-Won
    • Korean Security Journal
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    • no.36
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    • pp.177-200
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    • 2013
  • As we enter a high industrial society that widens the gap between the rich and poor, demand for the security services has grown explosively. With the growth in quantitative expansion of security services, people have also placed increased requirements on more sophisticated and diversified security services. Consequently, market outlook for private security services industry is positive. However, Korea's private security services companies are experiencing difficulties in finding a direction to capture this new market opportunity due to their small sizes and lack of management-strategic thinking skills. Therefore, we intend to offer a direction of development for our private security services industry using a management-strategy theory and the Analytic Hierarchy Process(AHP), a structured decision-making method. A resource-based theory is one of the important management strategy theories. It explains that a company's overall performance is primarily determined by its competitive resources. Using this theory, we could analyze a company's unique resources and core competencies and set a strategic direction for the company accordingly. The usefulness and validity of this theory has been demonstrated as it has often been subject to empirical verification since 1990s. Based on this theory, we outlined a set of basic procedures to establish a management strategy for the private security services companies. We also used the AHP method to identify competitive resources, core competencies, and strategies from private security services companies in contrast with public companies. The AHP method is a technique that can be used in the decision making process by quantifying experts' knowledge and unstructured problems. This is a verified method that has been used in the management decision making in the corporate environment as well as for the various academic studies. In order to perform this method, we gathered data from 11 experts from academic, industrial, and research sectors and drew distinctive resources, competencies, and strategic direction for private security services companies vis-a-vis public organizations. Through this process, we came to the conclusion that private security services companies generally have intangible resources as their distinctive resources compared with public organization. Among those intangible resources, relational resources, customer information, and technologies were analyzed as important. In contrast, tangible resources such as equipment, funds, distribution channels are found to be relatively scarce. We also found the competencies in sales and marketing and new product development as core competencies. We chose a concentration strategy focusing on a particular market segment as a strategic direction considering these resources and competencies of private security services companies. A concentration strategy is the right fit for smaller companies as a strategy to allow them to focus all of their efforts on target customers in a single segment. Thus, private security services companies would face the important tasks such as developing a new market and appropriate products for such market segment and continuing marketing activities to manage their customers. Additionally, continuous recruitment is required to facilitate the effective use of human resources in order to strengthen their marketing competency in a long term.

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Effects of Soil Aggregate Stability and Wettability on Infiltration and Evaporation (토양입단(土壤粒團)의 안정성(安定性)과 친수성(親水性)이 수분침투(水分浸透) 및 증발(蒸發)에 미치는 영향(影響))

  • Jo, In-Sang;Cho, Seong-Jin;Verplanke, H.;Hartmann, R.;De Boodt, M.
    • Korean Journal of Soil Science and Fertilizer
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    • v.18 no.2
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    • pp.121-127
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    • 1985
  • This study was designed to gain practical data on the use of soil conditioners for more efficient water managements and to establish the optimum levels of structural properties for soil conditioning. A sandy loam and a silt loam soil were each treated with two different soil conditioners, hydrophobic Bitumen or hydrophilic Uresol. The perspex tube 34 cm long were packed homogeneously with air dried soil up to 2 cm below the top, then covered over 2 cm of treated or untreated aggregates. The infiltration rate into the soil columns was measured under simulated rainfall condition. The evaporation study was carried out in the wind tunnel, and the changes of soil moisture distribution of the columns following and during the evaporation were determined by a gamma ray scanner. The infiltration rate of water into the soil column was increased to 18.7-50.8% by the Uresol treatment but it was decreased to less than 25% of control by the Bitumen treatment. Evaporation was decreased to 22.0-68.1% by the Bitumen treatment and to 38.7-68.4% by the Uresol treatment. The water use efficiency of Uresol treated column was increased to more than twice as much as that of untreated soil. Aggregate stability and wetting angle were related to water infiltration and evaporation. A positive and highly significant logarismic relationship was found between the infiltration rate and stability index-wetting angle, evaporation rate and instability index-wetting angle. It was considered that the structural stability is more important than wetting angle. This is true because the structural stability is always positively correlated to water saving, however wettability is positively correlated to the infiltration, and negatively correlated to water saving during the evaporation.

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Vegetation structure and environmental factors in Paksil-nup Wetland, Hapcheon (박실늪의 식생 구조와 환경 요인)

  • Kim, Cheol-Soo;Lee, Pal-Hong;Son, Sung-Gon;Oh, Kyung-Hwan
    • Journal of Wetlands Research
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    • v.2 no.1
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    • pp.31-40
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    • 2000
  • The flora, vegetation structure and physico-chemical characteristics of surface sediment were investigated in Paksil-nup wetland of Hapcheon-gun, Gyeongsangnam-do, Korea in 1990~1998. Ranges of the surface sediment characteristics such as pH, conductivity, organic matter, total nitrogen, available phosphorus, exchangeable K, exchangeable Ca, exchangeable Mg, and exchangeable Na were 4.36~4.34, $19.0{\sim}1260.0\;{\mu}mho\;cm^{-1}$, 0.01~6.35%, 0.001~0.14%, 0.01~0.31 mg/l00g, 1.01~13.98 ppm, 16.75~143.80 ppm, 0.93~14.85 ppm and 0.21~3.86 ppm, respectively. Percentages of the particle size such as sand, silt, and clay were 13.0~93.3%, 5.4~71.7%, and 0.5~37.5%, respectively. The flora of the study area was composed of 72 families, 182 genera, 223 species, 36 varieties and 2 form or total 261 kinds, and those were 45 kinds of vascular hydrophytes and 216 kinds of vascular hygrophytes. The life form of vascular hydrophytes was classified as 27 kinds (60%) of emergent plants, 8 kinds (18%) of submerged plants, 6 kinds (13%) of free-floating plants and 4 kinds (9%) of floating-leaved plants, respectively. The importance value of Salix nipponica was highest as 123.78 in the shrub and tree layers, and that of Trapa japonica was highest as 16.69 in the herb layer. The vegetation type was divided into two groups according to the association analysis. The vegetation of the littoral zone was classified into 7 associations according to the cluster analysis based on the coverage data. These results showed significant differences with those of stand ordination by correspondence analysis based on the species composition and by PCA based on the sediment properties. Factors affecting the distribution of the vascular hydrophytes and hygrophytes were the gradient of particle size, altitude, and water depth.

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An Analysis of Suitable site of Constructed Wetland using High Resolution Satellite Image and GIS in Kyoung-An Stream (고해상도 위성영상과 GIS를 이용한 인공습지 적지 분석 -경안천을 대상으로-)

  • Koh, Chang-Hwan;Jin, Do;Ha, Sung-Ryong
    • Journal of Wetlands Research
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    • v.10 no.2
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    • pp.115-128
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    • 2008
  • Various human activities such as the Urbanization and Industrialization are estimated the main factors to pollute the stream. Now days, numerous studies are carried out for managing non-point sources which have un-effect on water quality of streams by land-use and livestock. In case of Korea, a matter of concern that the management of Pal dang reservoir - the main water resources of the national capital region - has been occurring. Especially, large-scale constructed-wetlands are planned and constructed at the end of Kyoung-an stream. Additionally a lot of sewage treatment plants are newly installed and extended in this watershed. According to these efforts, water quality of Kyoung-an stream is predicted that would be improved. But the more detail and scientific analysis should be carried out for the water quality improvement, because, existing water quality improvement projects are not involved to analyze root of water quality deterioration and improvement plans. Therefore, this study aims to select suitable areas for constructed-wetlands and to calculate size of the constructed-wetlands for water quality improvement in Kyoung-an stream through the geographical pollutant distribution analysis and land-use pattern analysis by high resolution satellite image and suitable area analysis of constructed-wetlands by GIS(Geographic information system). The progress of this study is (1) to select maximum pollutant loaded area by geographical analysis based on water quality data, (2) to analyze land-use patterns using high resolution satellite image, (3) to select suitable areas of constructed-wetlands, (4) to calculate area and volume of chosen constructed-wetlands using GIS. Basically, sizes of constructed-wetlands are induced through the constructed-wetlands design index based on treatment ratio(provided by Korea Water Resources Corporation). As a result of this study, two areas are selected to construct constructed-wetlands. One of the area was $127,586m^2$ near by Yong-in sewage treatment plant, and the other area was $1,647m^2$ near by Ju-buk stream and Dae-dae stream.

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Dosimetric Influence of Implanted Gold Markers in Proton Therapy for Prostate Cancer (전립선암에 대한 양성자치료에서 금마커에 의한 방사선 선량분포의 영향)

  • Kwak, Jung-Won;Shin, Jung-Wook;Kim, Jin-Sung;Park, Sung-Yong;Shin, Dong-Ho;Yoon, Myong-Geun;Park, So-Ah;Kim, Dong-Wook;Lim, Young-Gyeung;Lee, Se-Byeong
    • Progress in Medical Physics
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    • v.21 no.3
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    • pp.291-297
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    • 2010
  • This study examined the dosimetric influence of implanted gold markers in proton therapy and the effects of their positions in the spread-out Bragg peak (SOBP) proton beam. The implanted cylindrical gold markers were 3 mm long and 1.2 mm in diameter. The dosimetric influence of the gold markers was determined with markers at various locations in a proton-beam field. Spatial dose distributions were measured using a three-dimensional moving water phantom and a stereotactic diode detector with an effective diameter of 0.5 mm. Also, a film dosimetry was performed using Gafchromic External Beam Treatment (EBT) film. The GEANT4 simulation toolkit was used for Monte-Carlo simulations to confirm the measurements and to construct the dose-volume histogram with implanting markers. Motion data were obtained from the portal images of 10 patients to investigate the effect of organ motions on the dosimetric influence of markers in the presence of a rectal balloon. The underdosed volume due to a single gold marker, in which the dose was less than 95% of a prescribed amount, was 0.15 cc. The underdosed volume due to the presence of a gold marker is much smaller than the target volume. However, the underdosed volume is inside the gross tumor volume and is not smeared out due to translational prostate motions. The positions of gold markers and the conditions of the proton-beam field give different impacts on the dose distribution of a target with implanted gold markers, and should be considered in all clinical proton-based therapies.

Success rate and marginal bone loss of Osstem USII plus implants; Short term clinical study (Osstem USII plus 임플란트의 단기간 성공률 및 변연골 흡수량 평가)

  • Kim, Sun-Keun;Kim, Jee-Hwan;Lee, Keun-Woo;Cho, Kyoo-Sung;Han, Dong-Hoo
    • The Journal of Korean Academy of Prosthodontics
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    • v.49 no.3
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    • pp.206-213
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    • 2011
  • Purpose: The aim of this study was to evaluate the clinical value of Osstem$^{(R)}$ USII plus system implants. Clinical and radiographic data were analyzed for 88 implants placed and functionally loaded for a 12 month period at the Yonsei University Dental Hospital. Materials and Method: Based on the patient's medical records, clinical factors and their effects on implant marginal bone resorption, distribution and survival rate were analyzed. The marginal bone loss was evaluated at implant placement and during a 6 to 12 months functional loading period. The independent sample t-test was used to evaluate the interrelationship between the factors (${\alpha}$=0.05), and one way repeated measures ANOVA was used to compare the amount of marginal bone resorption. Results: The cumulative survival rate for 88 implants was 100%. The marginal bone resorption from implant placement to prosthetic delivery was 0.24 mm and the average marginal bone resorption from prosthetic delivery to 12 months of functional loading was 0.19 mm. The total average bone resorption from implant placement to 12 months of functional loading was 0.43 mm. There were no statistically differences in the amount of marginal bone resorption when implants were placed in the maxilla or the mandible (P>.05), however, implants placed in the posterior areas showed significantly more marginal bone loss than those placed in the anterior areas (P<.05). Conclusion: Based on these results, the short term clinical success rate of RBM surface treated external connection domestic implants showed satisfactory results and the marginal bone loss was in accord with the success criteria of dental implants.

Characteristic for Long-term Trends of Temperature in the Korean Waters (한국 연근해 수온의 시공간적 장기변동 특성)

  • Seong, Ki-Tack;Hwang, Jae-Dong;Han, In-Seong;Go, Woo-Jin;Suh, Young-Sang;Lee, Jae-Young
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.16 no.4
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    • pp.353-360
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    • 2010
  • The result of analysis of the observed temperature data by the Serial Oceanography Investigation of National Fisheries Research and Development Institute (NFRDI) during last 41 years from 1969 to 2008 showed that sea surface temperatures in the East, West and South Sea of Korea were clearly increased. In case of 100m depth, temperature was increased in the South Sea of Korea, but it was decreased in the East Sea. Especially, the temperature around the coastal area in the East Sea was significantly decreased by the spatial distribution of long-term change of temperature on 100m depth. It should lead to the decreasing trend in the long-term change of temperature on 100 m depth in the entire East Sea. The increasing trend was clearly larger in wintertime than in summertime by a factor of about 2 It means that the long-term increasing trend of sea surface temperature in the Korean Waters is usually caused by the distinctive increasing trend in wintertime. As the results of the analysis of air temperature and wind speed on the 6stations around the coastal area in the Korean Waters, air temperature was found to be continuously increased, but wind speed to be gradually decreased in winter. The weakness of vertical mixing by decreasing of wind speed caused to make the surface mixed layer shallow. it could be considered that the increasing trend of surface temperature was caused by weak mixing between surface and intermediate layers.