• 오토저널
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• 제14권6호
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• pp.81-90
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• 1992

This paper deals with an experimental study on the initial condition of liquid film surface waves disintegration and investigation on the behavior of liquid film surface waves formed by the high speed air flow on the solid plane surface. The authors conducted the qualitative and quantitative study to in vestigate the liquid film flow phenomena, the liquid film disintegration mechanism, and droplet formation process with breaking the liquid film surface wave. The newly devised transparent rectangular test section which has semi-two-dimensional flow at the center of the bottom was introduced to perform the experimental study, and it can generate the uniform thickness liquid film at the bottom. The strobo streak camera was used to obtain the instantaneously transformed photographs. The electronic measuring device was also used to measure the liquid film thickness variation in order to perform the easy and effective analysis of complex flow phenomena in the air-water cocurrent flow.

• 한국수소및신에너지학회논문집
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• 제26권1호
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• pp.71-78
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• 2015

This study was performed to optimize the integrated thermal-alkali pre-treatment of flotation scum for the enhanced biodegradability. The optimum conditions of the integrated thermal-alkali pre-treatment were obtained using response surface methodology. The disintegration degree of carbohydrate (69.2%) and protein (57.3) were estimated under the optimum conditions. Although the optimum conditions were different, the disintegration degrees were similarly. A fermentative hydrogen batch test was conducted to evaluate the hydrogen production from scum with and/or without. The maximum hydrogen production from scum with pre-treatment was of 0.64 mol H2/mol hexoseadded, which about 1.4 times higher than without pre-treatment.

• BMB Reports
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• 제46권1호
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• pp.53-58
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• 2013

We constructed deletion mutants and seven point mutants by polymerase chain reaction to investigate the specificity of feline foamy virus integrase functional domains. Complementation reactions were performed for three enzymatic activities such as 3'-end processing, strand transfer, and disintegration. The complementation reactions with deletion mutants showed several activities for 3'-end processing and strand transfer. The conserved central domain and the combination of the N-terminal or C-terminal domains increased disintegration activity significantly. In the complementation reactions between deletion and point mutants, the combination between D107V and deletion mutants revealed 3'-end processing activities, but the combination with others did not have any activity, including strand transfer activities. Disintegration activity increased evenly, except the combination with glutamic acid 200. These results suggest that an intact central domain mediates enzymatic activities but fails to show these activities in the absence of the N-terminal or C-terminal domains.

• Journal of Pharmaceutical Investigation
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• 제40권5호
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• pp.297-304
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• 2010

The present work focuses on preparation of olanzapine, orally dispersing tablets by direct compression method. Effect of super disintegrant crospovidone, disintegration time, drug content on in vitro release has been studied. A factorial design was employed in formulating a prompt dispersible tablet. The selected independent variables crospovidone and fmelt showed significant effect on dependent variables i.e. disintegration time and percent drug dissolved. Disintegration time and percent drug dissolved decreased with increase in the level of crospovidone. The similarity factor $f_2$ was found to be 97.48 for the developed formulation indicating the release was similar to that of the marketed formulation. Pharmacokinetics of olanzapine after single-dose oral administration of orally disintegrating tablet in normal volunteers were evaluated and the results showed that PK parameters (Cmax, Tmax, AUC) of the designed ODT matrix were similar to those of commercial product, Zyprexa Zydis$^{(R)}$ as a reference.

• Journal of Pharmaceutical Investigation
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• 제4권4호
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• pp.26-37
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• 1974

Having measured physical canstant and dissolution rate of prednisolone powder, and tablets, also particle size, particle number of powder disintegration, hardness, friability of prednisolone tablets and having also compared it's interrelationship. We obtained the results as following. 1) Dissolution rate of prednisolone powder was determinded cube root rule and: the slope $({\alpha})$ was $3.1915{\times}10^{-2}$. 2) The tablet used in this study was fourteen kind of prednisolone tablets, two kinds of which were not conformity with prednisolone dissolution rate test of U.S.P. XVIII, but the rest of them were conformity with the same test (t60% was 4.3minute in average) 3) There was no significant interrelationship between disintegration, hardness, friability and dissolution rate of prednisolone tablet used in this study but we recognized the disintegration time was greatly influenced by the dissolution rate.

• 한국자원리싸이클링학회:학술대회논문집
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• 한국자원리싸이클링학회 2005년도 춘계임시총회 및 제25회 학술발표대회
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• pp.109-112
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• 2005

The electrical pulse separation of concrete samples for the recycling purpose has been investigated by the electrical disintegration method using the discharged high voltageimpulse. First, when the consumed energy increased in electrical crushing, fracture section area increased clearly. This result suggests that crushing energy was consumed efficiently. Secondly, when conventional crushing after electrical disintegration is compared with only conventional crushing, gravels are more stable after electrical crushing. Thus, electrical crushing makes it easy to recover gravels from wasted concrete. In the next year, more efficient recovery of gravel for wasted concrete by electrical disintegration will be investigated. Thus, actual wasted concrete crushing by electrical separation and combination of conventional crushing will be carried out.

• Journal of Pharmaceutical Investigation
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• 제15권3호
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• pp.140-150
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• 1985

The influences of three binders, hydroxypropyl cellulose(HPC), microcrystalline cellulose (MCC) and polyvinylpyrrolidone(PVP), on the transmittance of compression pressure from upper punch to lower punch and the disintegration of aspirin tablets prepared by direct compression were studied. The optimum concentration of three binders for the disintegration of aspirin tablets was about 20w/w% and several physical properties of the powder and tablets were also investigated. The tablet machine was specially made for the measurement of compression pressure of the tablets.

• 자원리싸이클링
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• 제21권5호
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• pp.44-49
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• 2012

재생률이 높은 폐신문지(old newspaper, ONP)를 부유선별법을 이용하여 탈묵을 진행하였을 시, 해리시간, 초음파처리에 따른 백색도, 잔류잉크농도(effective residual ink concentration, ERIC), 수율의 효과를 규명하였다. 또한 부유선별시 pH, 포수제에 따른 백색도, ERIC과 수율의 효과도 규명하였다. 해리시간이 증가할수록 백색도와 ERIC이 증가함을 보였으나 수율의 차이는 없었다. 해리시간이 30분일 때 백색도 58% ERIC 182.9 ppm이였고, 해리를 더 진행하더라도 백색도의 증가를 볼 수 없었다. 단 해리 된 ONP를 초음파발생장치를 이용하여 초음파처리를 했을 경우 단 2분의 해리시간으로도 58%이상의 백색도를 얻을 수 있었다. 초음파처리를 20분간하고, pH 11에서 포수제로 등유을 사용했을 때 백색도가 59.32%로 가장 높았다.

• 한국환경보건학회지
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• 제24권2호
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• pp.118-125
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• 1998

This study investigates the react characteristics to suggest the condition of the utilization and disintegration of food garbage as composting by varying the supply amount of air of the fermentation reactors. With the initial temperature and agitation velocity maintained 50$\circ$C and 1 rpm, the supply amount of air gives variety to 0.5, 1, 2, 4 l/kg$\cdot$ min. In the case of the amount of air operated at the 0.5 l/kg$\cdot$ min, reaction temperature shows a rising to the maximum 66$\circ$C after the 48hr, and the oxygen used rate of the micro-organisms shows the largest level at 18.4% after the 8hr. In the case of $NH_3, H_2, H_2S$ and SO$_2$ among the react gas, the sanitary utilization shows the possibility of the microorganisms gas disintegration, with most high gas generate rate. In the case of the amount of air operated at the 1, 2 and 4 l/kg$\cdot$ min, initial react was advanced rapidly and the product of the 72 hr after shows big weight reduction. As the experimentation result, when the amount of air operated at the 1 l/kg$\cdot$ min over, the reduction by disintegration would be more effectively, for the reactor maintains the color tone and shape of the straw (bulking agent).

• 유기물자원화
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• 제16권3호
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• pp.83-90
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• 2008

하수슬러지의 초음파 전처리시 용존성 유기물의 증가와 혐기성 생분해도 향상을 평가하였다. 하수슬러지의 초음파에 의한 가용화는 세포벽의 파괴로 인하여 용해성 화학적 산소요구량, 단백질 및 탄수화물의 농도 증가와 입자크기를 감소시켰다. 혐기성 생분해도 측면에서초음파 전처리는 메탄가스 발생량을 증가시켜 혐기성 생분해를 향상시키는 것으로 나타났다. 하수슬러지의 생화학적 메탄 잠재 발생량 실험결과 초음파 전처리 후 슬러지의 최종 메탄 수율은 294.3 ml $CH_4/gVS$로 나타나 전처리를 하지 않은 경우 211.3 ml $CH_4/gVS$에 비해 약 40 % 향상된 값을 보였다. 이와 같은 결과를 고려 시 하수슬러지의 가용화는 혐기성 생분해도 향상에 효과적인 것으로 나타났다.