• Parasites, Hosts and Diseases
• /
• 제52권5호
• /
• pp.507-511
• /
• 2014

Outbreaks of tick-borne disease cases in Santa Catarina, Brazil are known, but the presence of the pathogen DNA has never been determined. In this study, the first survey of Anaplasma marginale, Babesia bigemina, and Babesia bovis DNA on blood samples of 33 cattle from an outbreak in Ponte Alta Municipality, Santa Catarina, Brazil, has been carried out. A multiplex PCR detected 54.5% of animals were co-infected with 2 or 3 parasites, while 24.2% were infected with only 1 species. The most prevalent agent was B. bigemina (63.6%) followed by A. marginale (60.6%). This is the first report of tick-borne disease pathogens obtained by DNA analysis in Southern Brazil.

• Journal of fish pathology
• /
• 제28권3호
• /
• pp.125-131
• /
• 2015

This study was performed to determine the disinfection efficacy of influent seawater by application of mechanical filtration and UV disinfection system (MFUVDS) in decreasing disease outbreak of juvenile olive flounder (Paralichthys olivaceus). Bacterial disinfection rate of influent seawater following the MFUVDS application was 99.27%. Mortalities of the juvenile reared for 4 months were 20~30% lower than those of the control (25.8%~34.9%).

• Clinical and Experimental Pediatrics
• /
• 제63권4호
• /
• pp.119-124
• /
• 2020

A cluster of severe pneumonia of unknown etiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was isolated from lower respiratory tract sample as the causative agent. The current outbreak of infections with SARS-CoV-2 is termed Coronavirus Disease 2019 (COVID-19) by the World Health Organization (WHO). COVID-19 rapidly spread into at least 114 countries and killed more than 4,000 people by March 11 2020. WHO officially declared COVID-19 a pandemic on March 11, 2020. There have been 2 novel coronavirus outbreaks in the past 2 decades. The outbreak of severe acute respiratory syndrome (SARS) in 2002-2003 caused by SARS-CoV had a case fatality rate of around 10% (8,098 confirmed cases and 774 deaths), while Middle East respiratory syndrome (MERS) caused by MERS-CoV killed 861 people out of a total 2,502 confirmed cases between 2012 and 2019. The purpose of this review is to summarize known-to-date information about SARS-CoV-2, transmission of SARS-CoV-2, and clinical features.

• Korean journal of applied entomology
• /
• 제11권1호
• /
• pp.41-43
• /
• 1972

1. In order to investigate the epidemic outbreak of rice blast disease on the resistant variety Kwankon in 1969, this investigation was undertaken as a basis for breeding resistant varieties. 2. The 16 isolates collected from Kyunggi area were inoculated at the 3-4 leaf stage on 12 Japanese differential varieties used for identifying races under greenhouse conditions. Out of 16 isolates 15 were identified as C race group and one as N race group. Of the 15 rates, nine were C-8, two were C-7 and two were C-1. Of the remaining two isolates, one was similar to C-1, and the other was similar to C-5. 3. It is concluded that the epidemic in the resistant variety 'Kwanok' was due to the occurrence of the C race group, which can infect the Chinese type varieties.

• Korean Journal of Veterinary Service
• /
• 제30권2호
• /
• pp.251-258
• /
• 2007

Bovine brucellosis has occurred for years in Gyeonggi province under the national test and slaughter scheme. The serum agglutination test (SAT) is a diagnostic tool to confirm the disease despite the argument on its specificity. We selected 8 farms where only one or two individuals were diagnosed as brucellosis through SAT at the primary regular herd check and isolated the causative organism and characterized the species by species-specific PCR. The pathogen isolation was successful in 6 farms out of 8 farms by microbiological culture, showing the successful rate of 75%. The isolation rate of the causative organism represents 70% from supra-mammary lymph node and 60% from uterine tissues. They were characterized as Brucella abortus biovar 1 after biotyping by PCR, showing the fragment of 498 bp. Five of 8 farms were diagnosed as brucellosis two to four times more over the intervals of two or three months. Here in this study we briefly showed the correlation of the sporadic outbreak of brucellosis tested by SAT and the isolation of the causative organism. Moreover one or two reactors against brucellosis among considerable size of herd may indicate that SAT failed to detect potentially infected individuals in the incubation stage or chronic phase of the disease.

• Journal of Preventive Medicine and Public Health
• /
• 제54권4호
• /
• pp.245-250
• /
• 2021

Objectives: Jeju Province in Korea reported 627 coronavirus disease 2019 (COVID-19) cases between January 20, 2020, and March 31, 2021. This study analyzed the sources of infection among confirmed cases in Jeju Province, a self-governed island. Methods: The sources of infection were broadly categorized as follows: (1) infections from overseas (confirmed patients who reported travel overseas or contact with overseas travelers); (2) infections from outside Jeju Province (confirmed patients who had visited other provinces or had contact with individuals who had traveled to other provinces in Korea); and (3) unknown sources of infection (confirmed patients who were infected following contact with an infected person whose source of infection was unknown). The chi-square test was used to analyze the differences in the distributions of related variables for each source of infection. Results: Of the 627 confirmed cases, 38 (6.1%) were infections from overseas sources, 199 (31.7%) were from outside of Jeju Province, and 390 (62.2%) were from unknown sources. Jeju Province had no cases with an unknown source of infection during the first and second waves of the nationwide outbreak. Conclusions: Infections from overseas sources could be blocked from spreading to local communities in Jeju Province by conducting screening at the airport, along with the preemptive suspension of visa-free entry. In addition, considering the scale of the nationwide outbreak, measures must be established to delay outbreaks from unknown sources of infection caused by sources outside Jeju Province.

• Journal of the Korean Society of Systems Engineering
• /
• 제20권1호
• /
• pp.34-49
• /
• 2024

Since the outbreak of COVID-19, 'overcoming infectious disease' has emerged as a priority task for most policies. Each country has implemented policy programs to significantly shorten the vaccine development period with the goal of rapid vaccine development. This study judged this process to be a shock to the existing social and technological system and its recovery. Accordingly, the United States' Operation Warp Speed, CEPI's 100 days mission, and Japan's SCARDA were selected as examples of policy programs with 'rapid vaccine development' as their mission and analyzed difference from traditional vaccine development system in terms of rapid development. As a result, it was confirmed that the accumulation of innovative resources was shared as the key to achieving the mission in the preparation stage before the outbreak of an infectious disease. However, it was also possible to discover an approach to shortening the period of each stage without fundamentally changing the vaccine development structure itself.

• Korean Journal of Veterinary Service
• /
• 제35권4호
• /
• pp.255-261
• /
• 2012

Foot and mouth disease (FMD) is highly infectious disease of cloven-hoofed animals, particularly cattle, sheep, pigs and goats. Last outbreak reported in November, 2010 induced the enormous social and economical impacts. Culling of infected animals, movement control, and vaccination are the major control measures of FMD. The aim of this study was to detection foot-and-mouth disease virus (FMDV) in the soil and leachate from modeling burial for pig carcass as measured by real-time reverse transcriptase polymerase chain reaction (RT-PCR). FMDV and Coxsakievirus B1 (CVB1) were detected in soil by week 16 and Coxsakievirus B1 (CVB1) by weeks 12, respectively. FMDV and CVB1 also detected by weeks 8 in the leachate. Results from this study provides an evidence that FMDV could be inactivated for safe of pig carcasses infected with FMDV within 4 month in the carcass burial site.

• IMMUNE NETWORK
• /
• 제21권1호
• /
• pp.4.1-4.18
• /
• 2021

The global outbreak of coronavirus disease 2019 (COVID-19) is still threatening human health, economy, and social life worldwide. As a counteraction for this devastating disease, a number of vaccines are being developed with unprecedented speed combined with new technologies. As COVID-19 vaccines are being developed in the absence of a licensed human coronavirus vaccine, there remain further questions regarding the long-term efficacy and safety of the vaccines, as well as immunological mechanisms in depth. This review article discusses the current status of COVID-19 vaccine development, mainly focusing on antigen design, clinical trials in later stages, and immunological considerations for further study.

• Journal of Veterinary Science
• /
• 제25권4호
• /
• pp.51.1-51.11
• /
• 2024

Importance: Feline calicivirus (FCV)-associated viral systemic disease (VSD) is a severe systemic disease caused by virulent FCV strains and has a very poor prognosis. Objective: To evaluate the clinical characteristics of a nosocomial FCV-VSD outbreak involving 18 cats in Korea. Methods: Medical records of cats diagnosed with FCV-VSD from March to September 2018 at a referral veterinary hospital were reviewed. The patient's signalment, history, clinical features, diagnosis, treatment, and prognosis were evaluated. Results: Two outbreaks involving 18 cats diagnosed with FCV-VSD occurred over a 6-month period at a referral hospital in Korea. Anorexia, lethargy, fever, and limb edema were the most commonly observed clinical symptoms. Lymphopenia and macrothrombocytopenia were the most common hematological findings, and hyperbilirubinemia and increased levels of aspartate aminotransferase, creatine kinase, and serum amyloid A were the most frequent results of serum biochemistry. FCV was detected by reverse transcription polymerase chain reaction in 11 patients and the remaining 7 were suspected with FCV-VSD. The overall mortality rate was 72.2%. The hospital was closed and disinfected twice, and no additional outbreaks have occurred since the last patient. Conclusions and Relevance: The clinical and diagnostic characteristics and outcomes of FCV-VSD described in this study can be used to recognize and contain infectious diseases through quick action. To the best of the authors' knowledge, this is the first report of a nosocomial outbreak of FCV-VSD in Asia.