• Child Health Nursing Research
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• 제2권2호
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• pp.19-27
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• 1996

The purpose of this study is to explore the level of children's anxiety related to disease characteristics The subjects of this study were 72 childrens (6year-10 year) who were admitted to the pediatric wards at University Hospital and 24 healthy children, and 24 mothers of children with fatal & chronic illness. The data were collected with sarason's Anxiety scale for children & spielberger's State Trait Anxiety Inventory for mothers and analyzed of One way Anova, Duncun Test, Pearson correlation, and T-test. The results of this study were as follows : 1) There was significant difference in children's anxiety related to disease characteristics(P<0.01) Fatally ill children showed highest level of anxiety and chronically, acutely ill children in order. And there was no significant difference in anxiety between acutely ill children and healthy children. There was significant difference in anxiety between groups of ill and healthy children(P<0.01) .The anxiety of ill children was higher than that of healthy children. 2) There was no significant correlation between children's anxiety and their age. 3) There was no significant difference in children's anxiety related to frequency of hospital admission. 4) There was significant correlation between children's anxiety and duration of illness(P<0.01). The longer the duration of illness is, the higher children's anxiety is. 5) There was significant difference in mothers' anxiety between groups of fatally ill and chronically ill children(P<0.05). The anxiety of mothers of fatally ill children was higher than that of mothers of chronically ill children. 6) There was no significant correlation between children's anxiety of fatal and chronic illness and their mothers' anxiety.

• 대한치과의료관리학회지
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• 제10권1호
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• pp.22-32
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• 2022

This study investigated factors affecting care for elderly patients, management of systemic disease, infection management, improvement of medical care quality, and educational requirements, and provide basic data for quality care for elderly patients with systemic diseases. An online survey was conducted among dental hygienists working at dental institutions and data of 172 individuals were analyzed using the SPSS 21.0 program. Descriptive statistics was performed for general characteristics. For factor analysis by general characteristics, t-test and ANOVA were performed. For differences between groups Scheffe verification was performed. A correlation analysis between factors was performed using Pearson's correlation analysis, and a factor analysis affecting the improvement of healthcare quality was performed using multiple linear regression analysis. Care for elderly patients was 52.33/75, management of systemic disease was 12.65/17, and infection management was 96.92/130. Improvement of medical quality (institutional effort) was 22.87/35, and improvement of medical quality (personal effort) was 22.72/35. The most common educational needs were "necessary". Analysis revealed a positive correlation between factors.. Factors affecting improvement of medical quality (personal effort) were age, final academic background, place of work, and the presence or absence of annual medical examinations. The findings of this study indicate that there is a significant correlation between factors. For the qualitative care of elderly patients, education programs related to elderly characteristics, systemic diseases, and infection management should be actively conducted by dental hygienists, and interest and research on geriatric dental hygiene is needed, centering on associations and educational institutions.

• 보건의료산업학회지
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• 제7권3호
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• pp.111-123
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• 2013

The purpose of this study was to identify factors affecting stress and adaptation in newborn congenital heart disease patients of parents. Data were obtained through questionnaires from 181 newborn congenital heart disease inpatients of parents from P university in Y city. The data were analyzed SPSS 18.0, using descriptive statistics, Pearson correlation coefficients and stepwise multiple regression. Stress was negative correlated with level of patents adaptation. Social support, marital communication and family cohesion were positive correlated with level of patents adaptation. The explained variances for patents adaptation were 45.2% and factors affecting patients adaptation were congenital heart disease, family cohesion, stress, social support and marital communication. Educational intervention program for parents of newborn with congenital heart disease, reduce stress, and to increase the adaptation will be developed.

• 대한핵의학회지
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• 제37권1호
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• pp.13-23
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• 2003

Neurodegenerative disorders cause a variety of dementia including Alzheimer disease, frontotemporal dementia, dementia with Lewy bodies, corticobasal degeneration, progressive supranuclear palsy, and Huntington's disease. PET scan is useful for early detection and differential diagnosis of these dementing disorders. Also, it provides valuable information about clinico-anatomical correlation, allowing better understanding of function of brain. Here we discuss recent achievements PET studies regarding these dementing disorders. Future progress in PET technology, new tracers, and image analysis will play an important role in further clarifying the disease pathophysiology and brain functions.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제41권
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• pp.56.1-56.6
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• 2019

Background: Programmed cell death ligand 1 (PD-L1) is an immune checkpoint molecule that attenuates the immune response. PD-L1 contributes to failed antitumor immunity; thereby, blockade of PD-L1 with monoclonal antibody enhances the immune response. Recently, it was reported that PD-L1 was regulated by protein 53 (p53). Besides, cytokeratin 17 (CK17) is thought to be a diagnostic marker of oral squamous cell carcinoma (OSCC). Our aim was to evaluate the correlation between the immunohistochemical expression of PD-L1, p53 and CK17 with clinicopathological characteristics and disease-specific survival in patients with OSCC. Methods: A total of 48 patients with OSCC were included in this study. Immunohistochemical staining was performed to evaluate the correlation among the expressions of PD-L1, p53 and CK17, and furthermore the correlation among various clinicopathological factors, PD-L1, p53 and CK17. Results: The positive rate of p53, CK17, PD-L1 (tumor cells) and PD-L1 (tumor-infiltrating lymphocytes) was 63.2%, 91.7%, 48.9% and 57.1%. A statistically significant correlation between p53 expression and T stage and TNM stage (p = 0.049, p = 0.03, respectively) was observed. Also, a statistically significant correlation between p53 and PD-L1 (TCs) expression (p = 0.0009) was observed. Five-year disease-specific survival rate was not significantly correlated with gender, TNM stage, p53 expression, PD-L1 expression and CK17 expression. Conclusion: The expression of p53 and PD-L1 shows significantly positive correlation in oral squamous cell carcinoma in tumor cells. Also, a significant correlation between p53 expression and T stage and TNM stage was observed. No other significant correlation between PD-L1 staining or CK17 and clinical or pathologic characteristics was identified.

• 한국환경과학회지
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• 제25권6호
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• pp.839-851
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• 2016

The effect of weather on disease was investigated based on results reported in academic papers. Weather-sensitive disease was selected by analyzing the frequency distributions of diseases and correlations between diseases and meteorological factors (e.g., temperature, humidity, pressure, and wind speed). Correlations between disease and meteorological factors were most frequently reported for myocardial infarction (MI) (28%) followed by chronic ischemic heart disease (CHR) (12%), stroke (STR) (10%), and angina pectoris (ANG) (5%). These four diseases had significant correlations with temperature (meaningful correlation for MI and negative correlations for CHR, STR, and ANG). Selecting MI, as a representative weather-sensitive disease, and summarizing the quantitative correlations with meteorological factors revealed that, daily hospital admissions for MI increased approximately 1.7%-2.2% with each $1^{\circ}C$ decrease in physiologically equivalent temperature. On the days when MI occurred in three or more patients larger daily temperature ranges ($2.3^{\circ}C$ increase) were reported compared with the days when MI occurred in fewer than three patients. In addition, variations in pressure (10 mbar, 1016 mbar standard) and relative humidity (10%) contributed to an 11%-12% increase in deaths from MI and an approximately 10% increase in the incidence of MI, respectively.

• Journal of Nutrition and Health
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• 제41권4호
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• pp.327-340
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• 2008

This study was designed to investigate the correlation between nutrition status and cardiovascular disease in type 2 diabetes patients with metabolic syndrome. The subjects were 66 patients and divided into Non MS (a group without metabolic syndrome, n = 37) and MS (a group with metabolic syndrome, n = 29). The percentage of patients accompanying metabolic syndrome was 43.9% and family history such as DM, skipping meal and eating speed were higher in MS (P < 0.05) The average values of BMI, body fat (%), waist circumference were significantly higher in patients of MS than that of Non MS. For hamatological values, MS showed higher FRS, HOMA-IR, LDL-Cholesterol, CRP. Percentage of FRS was 21.63% in MS that is relatively higher in comparison with 16.81% in Non MS. Moreover, the incidence of cardiovascular disease appeared 13.8% in MS that is higher than 2.7% in Non MS. The intake of sodium and vitamin E were higher, but the intake of fat, vitamin A and zinc were lower in MS than in Non MS. Close correlations were elucidated among FRS, occurrence of cardiovascular disease, weight, waist circumference, Total-Cholesterol, LDLCholesterol, sodium in both groups. In conclusion, cardiovascular disease risk factors would be higher in type 2 diabetes patients with metabolic syndrome and there were distinctive patterns that were associated with hamatological values, nutrition intake risk factors. This result should be considered when designing nutrition study and intervetion programs.

• 한국정보통신학회논문지
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• 제26권5호
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• pp.755-762
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• 2022

본 논문에서는 학습 예측이 가능한 군집적 알고리즘으로 COVID-19에서 상황인식정보인 질병의 속성정보와 클러스터링를 이용한 군집적 알고리즘을 제안한다. 클러스터링 내에서 처리되는 군집 데이터는 신규 또는 새롭게 입력되는 정보가 상호관계를 예측하기 위해 분류 제공되는데, 이때 새롭게 입력되는 정보가 비교정보에서 오염된 정보로 처리되면 기존 분류된 군집으로부터 벗어나게 되어 군집성을 저하시키는 요인으로 작용하게 된다. 본 논문에서는 COVID-19에서의 질병속성 정보내 K-means알고리즘을 이용함에 있어 이러한 문제를 해결하기 위해 질병 상호관계 정보 추출이 가능한 사용자 군집 분석 방식을 제안하고자 한다. 제안하는 알고리즘은 자율적인 사용자 군집 특징의 상호관계를 분석학습하고 이를 통하여 사용자 질병속성간에 따른 클러스터를 구성해 사용자의 누적 정보로부터 클러스터의 중심점을 제공하게 된다. 논문에서 제안된 COVID-19의 다중질병 속성정보군집단위로 분류하고 학습하는 알고리즘은 적용한 모의실험 결과를 통해 사용자 관리 시스템의 예측정확도가 학습과정에서 향상됨을 보여주었다.

• 보건의료산업학회지
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• 제11권4호
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• pp.169-178
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• 2017

Objectives : In this study, we investigated the correlation of mental-and oral-health status with periodontal disease. Ultimately, we sought to make a positive contribution to the promotion of periodontal health and the prevention of periodontal disease. Methods : This study was analyzed using the data of KNHANES 2013-2015. The participants of this study were between 20 and 64 years old. The final selection was 1,512 adults. Results : Participants with a sleeping time of less than 6 hours and those who recognized stress showed higher periodontal disease. Number of decaying teeth, oral-health status, toothaches, and chewing problems were associated significantly with periodontal disease. To investigate the effects of general characteristics and mental and oral-health status on periodontal disease, a logistic regression analysis was conducted. Sex, age, education level, smoking status, oral-health status, and chewing problems were variables that affected periodontal disease. Conclusions : This study showed that mental-and oral-health status is closely related to periodontal disease. Therefore, it is expected that this will be used as basic data to effectively improve periodontal disease in adults.

• 식물병연구
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• 제9권2호
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• pp.68-71
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• 2003

이삭도열병 발병시기가 빠를수록 벼 수량은 비례하여 감소되는데 조생종인 진미벼의 경우 출수 초기에 발병된 벼는 2년간의 조사결과 83.9%와 81.6%가 각각 감수되었으며, 출수 30일과 42일 후에 발병될 경우에도 44.3%와 33.1%가 감수되었다. 이삭도열병 발생식기가 벼 수량에 미치는 영향을 추정하기 위하여 회귀 분석을 한 결과, 1999년은 y =-1.9729x + 71.878($R^2$ = 0.9764), 2000년은 y = ?1.6421x + 97.212($R^2$ = 0.8569)로 발병시기와 수량감소와는 매우 높은 부의 상관관계가 있었다. 중만생종인 추청벼의 경우에도 2년간의 조사결과 출수 초기에 발병된 벼는 64.9%와 47.8%가 감수되었으며, 출수 40일 후 발병된 경우 29.1%와 8.9%가 감수되었으며, 1999년은 y =-1-.2717x + 79.523($R^2$ = 0.9487), 2000년은 y = ?1.6872x + 74.545($R^2$ = 0.7993)로 발병시기와 수량감소와는 매우 높은 부의 상관관계가 있었다. 천립중 조사결과도 출수초기에 발별된 경우 백수가 많았으며, 건전구 대비 진미벼는 38.3%, 추청벼는 57.3% 정도였으며, 출수 40일 후 발병된 경우 건전구 대비 진미벼는 87.9%, 추청벼는 92.9%로 천립중이 가벼워 벼가 충실하게 성숙되지 않음을 알 수 있었다.