• Publications of The Korean Astronomical Society
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• v.27 no.4
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• pp.297-298
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• 2012

ANIR (Atacama Near InfraRed camera) is a near infrared camera for the University of Tokyo Atacama 1m telescope, installed at the summit of Co. Chajnantor (5,640 m altitude) in northern Chile. The high altitude and extremely low water vapor (PWV = 0.5 mm) of the site enable us to perform observation of hydrogen $Pa{\alpha}$ emission line at $1.8751{\mu}m$. Since its first light observation in June 2009, we have been carrying out a $Pa{\alpha}$ narrow-band imaging survey of nearby luminous infrared galaxies (LIRGs), and have obtained $Pa{\alpha}$ for 38 nearby LIRGs listed in AKARI/FIS-PSC at the velocity of recession between 2,800 km/s and 8,100 km/s. LIRGs are affected by a large amount of dust extinction ($A_V$~ 3 mag), produced by their active star formation activities. Because $Pa{\alpha}$ is the strongest hydrogen recombination line in the infrared wavelength ranges, it is a good and direct tracer of dust-enshrouded star forming regions, and enables us to probe the star formation activities in LIRGs. We find that LIRGs have two star-forming modes. The origin of the two modes probably come from differences between merging stage and/or star-forming process.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.40 no.3
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• pp.172-180
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• 2003

The purpose of this study is to observe the heat transfer process in in-vivo human muscle based on Proton Resonance Frequency(PRF) method in Magnetic Resonance Imaging(MRI). MRI was obtained to measure the temperature variation according to the heat transfer in phantom and in-vivo human calf muscle. A phantom(2% agarose gel) was used in this experiment. MR temperature measurement was compared with the direct temperature measurement using a T-type thermocouple. After heating agarose gel to more than 5$0^{\circ}C$ in boiling hot water, raw data were acquired every 3 minutes during one hour cooling period for a phantom case. For human study heat was forced to deliver into volunteer's calf muscle using hot pack. Reference data were once acquired before a hot pack emits heat and raw data were acquired every 2 minutes during 30minutes. Acquired raw data were reconstructed to phase-difference images with reference image to observe the temperature change. Phase-difference of the phantom was linearly proportional to the temperature change in the range of 34.2$^{\circ}C$ and 50.2$^{\circ}C$. Temperature resolution was 0.0457 radian /$^{\circ}C$(0.0038 ppm/$^{\circ}C$) in phantom case. In vivo-case, mean phase-difference in near region from the hot pack is smaller than that in far region. Different temperature distribution was observed in proportion to a distance from heat source.

• Journal of the Korean Society of School Health
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• v.2 no.1
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• pp.91-107
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• 1989

This study was designed to evaluate current level of school health practice in Chonbuk province and to analyze the relationship between school health practice and variables. All the subjects in this study were 140 schools themselves in Chonbuk province. Survey data was collected through the interviewed checklists from the widly accepted school health responsibilities of administration and practice and the direct observation by the interviewer. It was conducted from 1st of Nov. to 17 th of Dec, 1988. The major findings of this study are as follows: A. Level of school health practice was relatively low in score (Mean=64.5). $\cdot$ Healthful School Living -76.14 $\cdot$ School Health Service -71.29 $\cdot$ School Health Instruction -47.98 B. Strengths and Weakness field in School Health Practice. 1. Healthful School Living: Strengths: Waste disposal, Seating, Playground. Weakness: School site, Safety control. 2. School Health Service : Strenths : Health Appraisal, Follow up and Counseling. Weakness: Dental Health, Prevention and Control of Communicable Disease, Facilities and Equipment of Health Clinic. 3. School Health Instruction : Strength : None, Weakness : Program Organization, Curriculum Planning and Evaluation, Curriculum Content, Instructional Aids. C. Significance between degree of School Health Practice and Variables. 1. Healthful School Living : (1) Toilet : Area (p<0.001), No.of Class (p<0.001), School Nurse (p<0.05) (2) Water Supply : School Nurse (p<0.05) (3) Safety Control : School Nurse (p<0.05) 2. School Health Service : (1) Health Appraisal : School Nurse (p<0.05) (2) Follow up and Counseling : School Nurse (p<0.001) (3) Dental Health : Area (p<0.05), Level of School (p<0.05) (4) Prevention and Control of Communicable Disease : Level of School (p<0.001), School Nurse (p<0.05) (5) Emergency Care : Area (p<0.001), No. of Class (p<0.001), School Nurse(p<0.001) (6) Facilities and Equipment of Clinic : Level of School (p<0.001), No.of Class (p<0.001), School Nurse (p<0.001) 3. School Health Instruction: (1) Program Organization : No. of Class (p<0.05), School Nurse (p<0.001) (2) Curriculum Planning land Evaluation : School Nurse (p<0.001) (3) Instructional Aids : Level of School (p<0.001), School Nurse (p<0.05) Recommendation for the Improvement of School Health Practice are as follows : A. There should be further study to strengthen the school health practice, especially in the field of school health instruction. B. It is strictly required to employ and utilize school nurse at each school level not only for the school health service but also for the school health in struction. C. There should be much considerations about adequate size and easily accessible distance in school site.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.6
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• pp.1043-1051
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• 2017

Asphalt overlay on deteriorated concrete pavement has a problem of early damage due to reflective cracking. There is a need for a new method capable of reducing reflection cracking and ensuring the durability of pavement. The purpose of this study was to obtain durability of asphalt overlay with stress absorbing membrane interlayer (SAMI) using epoxy asphalt binder. The tensile performance, durability, water resistance and bonding performance of Epoxy-SAMI were evaluated by various tests. As a result of tests, Epoxy-SAMI meets the quality standard of the bridge waterproofing material. The repeated direct tensile test was carried out to investigate the effect of reflective cracking reduction. When the Epoxy-SAMI was applied, it had 1.2~1.56 times higher reflective cracking resistance than PSMA asphalt concrete with the thickness of 10cm even if the section thickness decreased. 4-point bending beam test results showed the number of fatigue failures increased 7.5 times when Epoxy-SAMI was applied. The Epoxy-SAMI was found to be effective in improving the durability of the asphalt pavement overlay because it serves to prevent reflective cracking, increase lifespan, and function as a waterproof layer.

• Environmental Analysis Health and Toxicology
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• v.31
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• pp.10.1-10.8
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• 2016

Objectives Aromatase inhibitors that block estrogen synthesis are a proven first-line hormonal therapy for postmenopausal breast cancer. Although it is known that standardized extract of Ginkgo biloba (EGb761) induces anti-carcinogenic effects like the aromatase inhibitors, the effects of EGb761 on steroidogenesis have not been studied yet. Therefore, the effects of EGb761 on steroidogenesis and aromatase activity was studied using a H295R cell model, which was a good in vitro model to predict effects on human adrenal steroidogenesis. Methods Cortisol, aldosterone, testosterone, and $17{\beta}$-estradiol were evaluated in the H295R cells by competitive enzyme-linked immunospecific assay after exposure to EGb761. Real-time polymerase chain reaction were performed to evaluate effects on critical genes in steroid hormone production, specifically cytochrome P450 (CYP11/ 17/19/21) and the hydroxysteroid dehydrogenases ($3{\beta}$-HSD2 and $17{\beta}$-HSD1/4). Finally, aromatase activities were measured with a tritiated water-release assay and by western blotting analysis. Results H295R cells exposed to EGb761 (10 and $100{\mu}g/mL$) showed a significant decrease in $17{\beta}$-estradiol and testosterone, but no change in aldosterone or cortisol. Genes (CYP19 and $17{\beta}$-HSD1) related to the estrogen steroidogenesis were significantly decreased by EGb761. EGb761 treatment of H295R cells resulted in a significant decrease of aromatase activity as measured by the direct and indirect assays. The coding sequence/Exon PII of CYP19 gene transcript and protein level of CYP19 were significantly decreased by EGb761. Conclusions These results suggest that EGb761 could regulate steroidogenesis-related genes such as CYP19 and $17{\beta}$-HSD1, and lead to a decrease in $17{\beta}$-estradiol and testosterone. The present study provides good information on potential therapeutic effects of EGb761 on estrogen dependent breast cancer.

• Korean Journal of Food Science and Technology
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• v.47 no.1
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• pp.63-69
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• 2015

The aim of this study was to investigate the deformation of packaging materials used for ready-to-eat (RTE) foods after the retort process and microwave heating. From the multilayer films consisting of polyethylene terephthalate (PET), polyamide (PA), and cast polypropylene (CPP) in a stand-up pouch form used for RTE foods, some deformation of the CPP layer, which was in direct contact with the food, was observed after the retort process and microwave heating. The damage was more severely caused by microwave heating than by the retort process. This may be attributed to diverse factors including the non-uniform heating in a microwave oven, the sorption of oil into the packaging film, and the different characteristics of food components such as viscosity, salt and water content. The development of heat-resistant packaging materials and systems suitable for microwave heating of RTE foods is required for the safety of consumers.

• Applied Chemistry for Engineering
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• v.9 no.3
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• pp.355-360
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• 1998

Reduction activity of precious metal-loaded HZSM-5 for NO has been studied and was compared to that of Cu-HZSM-5 in the presence of excess oxygen. It was found that among the catalysts used in this study, Ru-HZSM-5 was the most active catalyst for the reduction of NO to $N_2$ in the absence of hydrocarbon reductant. The highest conversion obtained was 45%. No severe inhibition of water vapor to the reduction was observed. It is suggested that the higher catalytic activity of Ru-HZSM-5 may result from the better ability to oxidize NO to $NO_2$ in the presence of excess oxygen. A proposed reaction mechanism for the reduction of NO to $N_2$ in the presence of excess oxygen is that NO is oxidized to $NO_2$ on the surface of Ru-HZSM-5 catalyst and the adsorbed $NO_2$ on the surface is then decomposed to $N_2$. $NO_2$ is supposed to the reaction.

• Transactions of the Korean Society of Automotive Engineers
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• v.14 no.4
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• pp.1-11
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• 2006

The aim in this study is to develop the combined EGR system with a non-thermal plasma reactor for reducing exhaust emissions and improving fuel economy in turbo intercooler ECU common-rail diesel engines. In this study, the characteristics of soot, CO and $CO_2$ emissions under four kinds of engine loads are experimentally investigated by using a four-cycle, four-cylinder, direct injection type, water-cooled turbo intercooler ECU common-rail diesel engine with a combined plasma exhaust gas recirculation(EGR) system operating at three kinds of engine speeds. The EGR and non-thermal plasma reactor system are used to reduce $NO_x$ emissions, and the non-thermal plasma reactor and turbo intercooler system are used to reduce soot and THC emissions. The plasma system is a flat-to-flat type reactor operated by a plasma power supply. The fuel is sprayed by pilot and main injections at the variable injection timing between BTDC $15^{\circ}$ and ATDC $1^{\circ}$ according to experimental conditions. It is found that soot emissions with increasing EGR rate are increased, but are decreased as the applied electrical voltage of the non-thermal plasma reactor is elevated at the same engine speed and load. Results also show that CO and $CO_2$ emissions are increased as EGR rate is elevated, and CO emissions are increased, but $CO_2$ emissions are decreased as the applied electrical voltage of the non-thermal plasma reactor is elevated at the same engine speed and load.

• Journal of the korean academy of Pediatric Dentistry
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• v.24 no.1
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• pp.204-219
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• 1997

The use of fluoride is one of the most effective methods for caries prevention. Fluoridation of public water supply has been recognized, for many years, as an effective way to reduce dental caries. The fluoride supplement has been recommended when the natural fluoride was unavailable or below the optimal range. However the mechanism of caries prevention by fluoride has not yet been clarified and it is well known that an overdose of fluoride results inacute and chronic toxicity, especially dental fluorosis. Fluoride mouthrinsing solution is widely used in dentistry due to its effectiveness in carrying anticariogenic action. Understanding the effects of fluoride mouthrinsing solution on human gingival fibroblasts will provide the safety rationale for its use during the caries preventive therapy. The purpose of this study was to evaluate the cytotoxic effect of fluoride mouthrinsing solution on the human gingival fibroblast in vitro. The human gingival fibroblasts were cultured from healthy gingiva on the extracted deciduous teeth of children. Cells were inoculated into a 24-well plate with $1{\times}10^4cells/well$ of medium at $37^{\circ}C$, 100% humidity, 5% $CO_2$ incubator for 24 hours. And the cells were counted by using the hemocytometer at each designed study. Human gingival fibroblasts were cultured in growth medium after one minute application range of 0.02%-0.2% NaF solution and 0.1% $SnF_2$ solution. The cells used in this study were between fifth to eighth passage number. The cell morphology was examined by inverted microscope and cell proliferation was measured by incorporating $[^3H]$-thymidine into DNA. DNA synthesis by human gingival fibroblasts was assessed by $[^3H]$-thymidine uptake assays while the cell activity was measured by MTT assay. Each concentrated fluoride mouthrinsing solution was estimated for its biocompatability with fibroblasts by the tissue culture technique. The results of this study were as follows : 1. It was observed that at 0.05%, 0.2% NaF mouthrinsing solution the cytoplasmic processes became globular. When 0.1% $SnF_2$ mouthrinsing solution was applied, the cytoplasmic process and cell morphology were disappeared. 2. DNA synthetic activity was reduced regardless of the concentration of the fluoride mouthrinsing solution. However, the result is statistically insignificant except 0.1% $SnF_2$ mouthrinsing solution(p<0.05). 3. Our results indicate that 0.02%, 0.05% concentrations of NaF mouthrinsing solution caused minimal cytotoxicity. But 0.2% NaF and 0.1% $SnF_2$ concentration were a significant difference between the cell activity in the experimental group and control group (p<0.05). 4. After appling 0.05% & 0.02% NaF fluoride mouthrinsing solution, cell activity was restored to the control groups level according to incubating time. The results suggest that direct exposure to fluoride solution inhibits gingival fibroblast activity. Therefore, for the most effective use of fluoride use, lowering the concentration of fluoride mouthrinsing is advisable because it maintains biocompatability and free ion in the oral fluid.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.10
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• pp.1508-1512
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• 2016

This study was performed to investigate the ameliorating effect of a mixture of extracts from Houttuynia cordata Thunb, Nelumbo nucifera G. (leaf), and Camellia sinensis (seed) (MIX) on acute ethanol-induced hangover in Sprague-Dawley rats. Plasma ethanol and acetaldehyde levels in MIX-treated rats significantly decreased at 3 h and 5 h after acute ethanol administration (25%, 3 g/kg body weight/d) as compared to ethanol-treated rats. Hepatic alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities were significantly higher in MIX-treated rats than in ethanol-treated rats. MIX exhibited high ADH and ALDH activities on direct assays using S9 rat liver fraction for ethanol metabolic enzymes clearance action. These results suggest that MIX could alleviate ethanol-induced hangover symptoms by elevating activities related to hepatic ethanol-metabolizing enzymes against ethanol induced metabolites, and MIX should be further developed to be a new anti-hangover material.