• Journal of Institute of Control, Robotics and Systems
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• v.10 no.11
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• pp.1089-1094
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• 2004

Diseases in the gastro-intestinal track are on an increasing trend. In order to diagnose a patient, the various signals of the digestive organ, such as temperature, pH, and pressure, can offer the helpful information. Among the above mentioned signals, we choose the pressure variation as a monitoring signal. The variation of a pressure signal of the gastro-intestinal track can offer the information of a digestive trouble or some clues of the diseases. In this paper, a pressure monitoring system for the digestive organs of a living pig is presented. This system concept is to transmit the measured biomedical signals from a transmitter in a living pig to wireless receiver that is positioned out of body. The integrated solution includes the following parts: (1) the swallow type pressure capsule, (2) the receiving set consisting of a receiver, decoder box, and PC. The merit of the proposed system if that the monitoring system can supply the precise and repeatable pressure in the gastro-intestinal track. In addition, the design of low power consumption enables it to keep sending reliable signals while the pressure capsule is working in the digestive organ. The subject of the study for the pressure monitoring system is in-vivo experiments for a living pig. We achieved the pressure tracings in digestive organs and verified the validity of system after several in-vivo tests using pressure monitoring system. As a result, we found each organ has its own characterized pressure fluctuation.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.8 s.173
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• pp.57-63
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• 2005

Development of a locomotive mechanism fer the capsule type endoscopes will largely enhance the ability to diagnose disease of digestive organs. In connection with it, most of researches have focused on an installable locomotive mechanism in the capsule. In this paper, it is introduced that the movement of a capsule type endoscope in digestive organ can be manipulated by magnetic force produced outside human body. Since the magnetic force is provided by permanent magnets, no additional power supply to the capsule is required. Using a robotic manipulator for locating the external magnet, the capsule motion control system can cover the whole human digestive organs. This study is particularly concentrated on dither motion effect to improve the mobility of capsule type endoscope. It was experimentally found out that the friction coefficient between the capsule and digestive organ can be remarkably reduced by superposing yawing or rolling dither motion on the translatory motion. In this paper, the experimental results obtained with the direction, amplitude and frequency of sinusoidal dither motion changed is reported.

• Journal of Fisheries and Marine Sciences Education
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• v.26 no.2
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• pp.401-420
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• 2014

This study aims to analyze middle school students' systemic thinking to express organic relations between different organ systems about the movement of food and air and teachers' reflective thinking about science teaching through their reflective journals after the lesson of digestion, circulation, respiration and excretion. Firstly, when investigating the moving route of hamburger eaten inside the body, students expressed the names, locations and forms of organs in the digestive system more than those in the circulatory system or the excretory system. When investigating the moving route of a painkiller taken inside the body, students seemed to have more difficulty in expressing the related organ systems than when investigating the moving route of other things, and they mostly drew pictures of organs in the digestive system as done for the moving route of hamburger. However, when investigating the moving route of water drunk inside the body, students mostly described organs in the digestive system but drew more pictures of organs in the excretory system, than when investigating the moving route of other things. When investigating the moving route of air inhaled inside the body, students mostly drew pictures of organs in the respiratory system, but the rate of their drawing pictures of circulatory organs was low. Secondly, this study analyzed one of the teachers' reflective journals, named Mr. Park. According to his journal, students showed different levels of understanding of organ names, depending on their degrees of familiarity with each organ, and in regard to the locations of organs, science teachers mostly aim to achieve learning objectives so much that they often forget to instruct the locations of organs in fact. As for the forms of organs, science teachers mostly spend so much time explaining the functions of organs that they often forget to describe the exact form of each organ.

• The Korean Journal of Malacology
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• v.17 no.1
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• pp.27-33
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• 2001

The Ovarian developmental phases of the reproductive cycle of Rapana venosa can be classified into five successive stages by histological study: early active stage (September to February), late active stage (December to April), ripe stage (March to July), partially spawned stage (May to August), and recovery stage (June to September). To understand the characteristics of nutrient storage and utilization in the digestive gland cells with ovarian developmental phases, we examined the digestive gland - which is the major nutrient supply organ associated with ovarian development of the female purple shell - by biochemical methods. Total protein contents in the digestive gland tissues increased in March (late active stage) and reached the maximum in May (ripe and partially spawned stages), and then their levels sharply decreased in July (partially spawned and recovery stages). Total lipid contents in the digestive gland tissues reached the maximum in January (early active stage). Thereafter, their levels rapidly decreased from May (ripe and partially spawned stages) and reached a minimum in July (partially spawned and recovery stages). The total DNA contents did not significantly change regardless of the different developmental stages of the ovary. However, it was also found from biochemical analysis that changes in total RNA content follow the same seasonal cycling to protein. These results indicate that the digestive gland is an important energy storage and supply organ in purple shells, and that the nutrient contents of the digestive gland change in response to gonadal energy needs.

• Journal of Nutrition and Health
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• v.27 no.8
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• pp.828-836
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• 1994

A low level exposure experiment was conducted on growing rats to investigate the accumulation and organ distribution of protein bound cadmium compared with cadmium chloride. Male Sprague-Dawley rats were fed for 21days with one of the semisynthetic diets, which contains cadmium as either bovine liver- or kidney meal bound cadmium, cadmium chloride with uncontaminated liver meal or cadmium chloride without organ meal, in the levels of ca. 0.5, 1 and 1.5mg/kg diet, respectively. After 21days of exposure cadmium was accumulated in liver, kidney and gastrointestinal tracts depending upon cadmium levels in diet. Inspite of very low cadmium accumulation in whole blood, it tends also to increase with dietary cadmium levels. The blood cadmium concentration of animals fed organ meal containing diets was about 4-7 fold higher than that without organ meal, regardless of cadmium was intrinsically bound to protein or not. However, significant effects of organ protein on cadmium accumulation in liver, kidney and digestive tracts were not detectable, when cadmium was supplemented as cadmium chloride. On the other hands, animals fed diet containing ca. 1.5mg Cd/kg as organ bound cadmium retained more cadmium in liver, kidney and digestive tracts compared to cadmium chloride with organ meal, whereby the increase of cadmium concentration in kidney was greater then in liver. However, when the concentration of protein bound cadmium was<1mg/kg diet, organ bound cadmium was not significantly different from cadmium chloride in bioavailability and organ distribution. From this result it is suggested that the intestinal absorption of protein bound cadmium is influenced of the amount of cadmium bound in protein. When cadmium concentration in protein is relatively low, protein bound cadmium seems to be absorbed in the same way as cadmium ions are absorbed. However, when the concentration is high, at least a small amount of intact protein bound cadmium could be absorbed and accumulated selectively in kidney.

• The Korean Journal of Malacology
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• v.20 no.1
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• pp.55-63
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• 2004

Gonadosomatic index, condition index and reproductive cycle with the gonadal development of the female Octopus ocellatus were investigated by histological observations and morphometric data, from January to December, 2000. And changes in biochemical components of the ovary and the trunk tissues including the digestive organ associated with gonadal development were studied by biochemical analysis from January to October, 2001. The specimens were collected at the coastal waters of Buan, Jeollabuk-do, Korea, from January 2000 to October 2001. O. ocellatus is a dioecious organism. The gonad of O. ocellatus locates medially in posterior region of the body. Morphology of the ovary shows round and oval in shape, the average diameter and external colour of ripe ovary was 32 mm and semitransparent light brown in colour. As the ovary was getting mature, transparent elongated eggs covered with chorion were present in the ovarian cavity. Monthly changes in the gonadosomatic index (GSI) showed a similar pattern with those of the condition index. The GSI and condition index began to increase in March and reached the maximum in April. And then, their values decreased from May and reached the minimum in September. Reproductive cycle of O. ocellatus can be categorized into five successive stages: early developing stage (September to December), late developing stage (November to March), ripe stage (March to May), partially spawned stage (April to June), and degenerative/resting stage (June to October). Follicle cells attached to an oocyte were involved in vitellogenesis in the cytoplasm of the vitellogeneic oocyte and formation of chorion (secondary egg membrane) of the ovarian eggs. Spawning occurred between April and June. The spawning period was once a year and the peak took place between May and June. This species belongs to semelparity. According to changes in biochemical contents of the ovary and the digestive organ, monthly variations of moisture, total protein, total lipid and glycogen contents (%) in the ovary showed a negative correlationship with those of the trunk tissues including the digestive organ. Accordingly, it is assumed that the ovary only may be received nutrient supply (total lipid content) for gonadal development from the trunk tissues including the digestive organ (r = -0.55, p < 0.05).

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1068-1073
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• 2005

Development of a locomotive mechanism for the capsule type endoscopes will largely enhance the ability to diagnose disease of digestive organs. In connection with it, most of the researches have focused on an installable locomotive mechanism in the capsule. In this paper, it is introduced that the movement of a capsule type endoscope in digestive organ can be manipulated by magnetic force produced outside human body. Since the magnetic force is provided by permanent magnets, no additional power supply to the capsule is required. Using a robotic manipulator for locating the external magnet, the capsule motion control system can cover the whole human digestive organs. This study is particularly concentrated on dither motion effect to improve the mobility of capsule type endoscope. It was experimentally found out that the friction coefficient between the capsule and digestive organ can be remarkably reduced by superposing yawing or rolling dither motion on the translatory motion. In this paper, the experimental results obtained while the direction, amplitude and frequency of sinusoidal dither motion were changed are reported.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.196-201
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• 2005

Diseases in the gastro-intestinal tract are on an increasing trend. In order to diagnose a patient, various signals of the digestive organ, such as temperature, pH, and pressure, can offer the helpful information. Among the above mentioned signals, we choose the pressure variation as a monitoring signal. The variation of a pressure signal of the gastro-intestinal tract can offer the information of a digestive trouble or some clues of the diseases. In this paper, a pressure monitoring system for the digestive organs of a living pig is presented. This is why a pig's gastro-intestinal tract is very similar as human's. This system concept is to transmit the measured biomedical signals from a transmitter in a living pig to a wireless receiver that is positioned out of body. The integrated solution includes the swallow type pressure capsule and the receiving set consisting of a receiver, decoder circuit. The merit of the proposed system is that the monitoring system can supply the precise and a durable characteristic to measure and to transmit a signal in the gastro-intestinal tract. We achieved the pressure tracings in digestive organs and verified the validity of system after several in-vivo tests using the pressure monitoring system. Through various experiments, we found each organ has its own characterized pressure fluctuation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1388-1391
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• 2006

Jangwi(腸胃) was recorded to Young Chu(靈樞)'s volume 33. Also, This Was recorded in Tae So(太素)‘s volume 10 Sindo Jangdo(身度 腸道), Gap Eul(甲乙)’s volume 2 Goldojangdojangwisosujechil(骨度腸道腸胃所受第七) and You Gyung(類經)‘s volume 4 Jangsnagyou jangwidaesojisu(臟象類 腸胃大小之數). Reason which call that it is Jangwi(腸胃) is that is describing length, width, diameter, weight, capacity, bends state of digestive organ from mouth to rectum. This chapter can not be understood in view of yin and yang five elements with Makedo(맥도), Goldo(骨度). This chapter can approach from specially viewpoint that is anatomy. Name of This chapter's terminology and position and types are very realistic. I feel pity that study does not exist about this. Therefore, I compared with comments of several doctors and modern anatomy. I believe that will be beaconed to understand This chapter.

• Environmental Analysis Health and Toxicology
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• v.22 no.2 s.57
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• pp.119-128
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• 2007

The present study was conducted to find out effect of PFOS on survival, activity, growth and organ structure of the melania snail, Semisulcospira gottschei. Experimental groups were composed of one control condition and four PFOS exposure condition (0.1, 0.5, 1.0 and 5.0 mg/L). After 16 week exposure, survival rate and activity were not significantly influenced at the two lower exposure groups, 0.1 and 0.5 mg/L, but they were significantly reduced in 1.0 and 5.0 mg/L groups. Total weight and meat weight rate (MWR) were reduced in PFOS exposure group in comparison to control group. Also, histological degenerations such as acidification of mucous, necrosis and split of muscular fiber bundle, atrophy of anterior pedal gland were recognized in the foot. Hepatopancreas showed the atrophy and degeneration of the digestive cell, vacuolation of digestive gland and closure of lumen in digestive gland.