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Diverse imaging characteristics of a mandibular intraosseous vascular lesion

  • Handa, Hina;Naidu, Giridhar S.;Dara, Balaji Gandhi Babu;Deshpande, Ashwini;Raghavendra, Raju
    • Imaging Science in Dentistry
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    • v.44 no.1
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    • pp.67-73
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    • 2014
  • Intraosseous vascular lesions of the maxillofacial region are rare, and the differential diagnosis of intraosseous vascular malformations from other jaw lesions can be challenging. In the present case, magnetic resonance imaging and three-dimensional computed tomographic angiography (CTA) was used for diagnosis, and the lesion was treated wih surgical excision. Diverse characteristics such as the "honeycomb" and "sunburst" radiographic appearances and the absence of major peripheral feeder vessels in the CTA were noted. Intraosseous vascular malformations have a varied radiographic appearance, and the nomenclature of these lesions is equally diverse, with several overlapping terms. Pathologists do not generally differentiate among intraosseous vascular lesions on the basis of histopathology, although these lesions may present with contrasting immunohistochemical and clinical behaviors requiring varied treatment strategies. This case report highlights the need for multiple imaging modalities to differentiate among vascular lesions, as well as to better understand the behaviors of these unique lesions.

Perfusion MR Imaging of Seizure-related Cerebral Cortical Lesion: A Case Report (발작에 의한 대뇌피질 병변의 관류 MR영상: 증례 보고)

  • Seo, Hyemin;Choi, Dae Seob;Shin, Hwa Seon;Son, Seungnam
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.4
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    • pp.312-315
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    • 2013
  • When cerebral cortical hyperintensities on diffusion-weighted image are seen in patients with suspected acute stroke accompanying seizure, it is necessary to differentiate whether they are caused by infarction or seizure-related change. We report a case of seizure-related cortical hypertensities in a patient with suspected acute infarction. With perfusion MR imaging, we could differentiate from acute infarction.

COMPARATIVE ANALYSIS OF PSYCHOPHYSIOLOGICAL REACTIVITY TO AUDITORY STIMULATION WITH AUTOMOBILE HORNS (자동차 경적소리에 대한 심리생리학적 반응 비교)

  • Estate Sokhadze
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 1999.03a
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    • pp.221-230
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    • 1999
  • Automobile horn's psychoacoustic characteristic and significance as a anturalistic signal of danger makes it a valuable auditory stimulus to study such psychophysiological responses as startle, orienting and defense reactions. However, comparison and differentiation of physiological responses to commercially available horns is a complicated task due to small contrast of technical features of horns and influence of such processes as habituation on physiological outcome with increased number of auditory stimulation trials. In the study on 10 college students we performed comparative analysis of tonic and phasic reactivity of physiological responses mediated by autonomic nervous system in order to identify role of habituation and decrement of autonomic responsivity, as well as possibility o differentiate subjectively most and least preferred and subjectively more appropriate horns according to physiological manifestations. It was showed that electrodermal and cardiovascular reactivity have concurrent patterns of adaptation to repeated stimulation, namely skin conductance variables habituated, cardiac reactivity failed to show signs of habituation, while vascular component of response were facilitated demonstrating marked sensitization. Differentiation of Physiological responses to horns with respect to their subjective rating scores was possible, however electrodermal reactivity was effective only at the first block of trials, while phasic and tonic cardiovascular reactivity differentiate responses during whole course of experiment. There are discussed possible autonomic mechanisms involved in mediation of observed results.

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Satellite Cells Isolated from Adult Hanwoo Muscle Can Proliferate and Differentiate into Myoblasts and Adipose-like Cells

  • Kook, Sung-Ho;Choi, Ki-Choon;Son, Young-Ok;Lee, Kyung-Yeol;Hwang, In-Ho;Lee, Hyun-Jeong;Chang, Jong-Soo;Choi, In-Ho;Lee, Jeong-Chae
    • Molecules and Cells
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    • v.22 no.2
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    • pp.239-245
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    • 2006
  • This study examined whether adult bovine muscle satellite cells from 30-month-old Hanwoo cattle are multipotential. The satellite cells were found to have the potential to proliferate and differentiate into myoblasts with the formation of multinucleated cells. In addition, treatment with the peroxisome proliferator activating receptor-${\gamma}$ ($PPAR{\gamma}$) agonist, rosiglitazone, promoted their trans-differentiation into adipocytes with significant increases in glycerol accumulation and glycerol-3-phosphate dehydrogenase activity. Western blot analysis revealed that increased levels of the adipocyte fatty acid-binding protein, $PPAR{\gamma}$ and of CCAAT/enhancerbinding protein were closely related to rosiglitazoneinduced differentiation of the cells. These findings demonstrate that satellite cells from adult Hanwoo cattle are multipotent, and that their trans-differentiation into adipocytes can be induced by rosiglitazone.

Expressional Subpopulation of Cancers Determined by G64, a Co-regulated Module

  • Min, Jae-Woong;Choi, Sun Shim
    • Genomics & Informatics
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    • v.13 no.4
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    • pp.132-136
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    • 2015
  • Studies of cancer heterogeneity have received considerable attention recently, because the presence or absence of resistant sub-clones may determine whether or not certain therapeutic treatments are effective. Previously, we have reported G64, a co-regulated gene module composed of 64 different genes, can differentiate tumor intra- or inter-subpopulations in lung adenocarcinomas (LADCs). Here, we investigated whether the G64 module genes were also expressed distinctively in different subpopulations of other cancers. RNA sequencing-based transcriptome data derived from 22 cancers, except LADC, were downloaded from The Cancer Genome Atlas (TCGA). Interestingly, the 22 cancers also expressed the G64 genes in a correlated manner, as observed previously in an LADC study. Considering that gene expression levels were continuous among different tumor samples, tumor subpopulations were investigated using extreme expressional ranges of G64-i.e., tumor subpopulation with the lowest 15% of G64 expression, tumor subpopulation with the highest 15% of G64 expression, and tumor subpopulation with intermediate expression. In each of the 22 cancers, we examined whether patient survival was different among the three different subgroups and found that G64 could differentiate tumor subpopulations in six other cancers, including sarcoma, kidney, brain, liver, and esophageal cancers.

Application of alkaline phosphatase staining of cytology specimen for differential diagnosis of canine osteosarcoma (세포 검사시료에서 alkaline phosphatase 염색법을 활용한 개 골육종의 감별 진단)

  • Park, Byoung-Yong;Park, Chul;Cho, Ho-Seong
    • Korean Journal of Veterinary Service
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    • v.34 no.4
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    • pp.397-401
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    • 2011
  • Aspiration of lytic bone lesions is an excellent diagnostic test in the initial evaluation of primary bone tumor. However, cytologically, it can be difficult to differentiate osteosarcoma (OSA) from other bone neoplasms, including fibrosarcoma, chondrosarcoma, synovial cell sarcoma, malignant fibrous histiocytoma and malignant peripheral nerve sheath tumor. The purpose of this study is to introduce alkaline phosphatase (ALP) staining to differentiate OSA from other mesenchymal tumors. Tumors actively producing bone are specifically positive for ALP staining. Unstained, cytologic specimens were incubated for 10 minutes with nitroblue tetrazolium chloride/5-bromo-4-chloro-3-indolyl phosphate toluidine salt-phosphatase substrate. Among 20 cases of cytology specimen, 14 were positive for ALP staining and histopathology, 6 were negative for ALP staining and histopathology. ALP staining was 100% sensitive and specificity for the diagnosis of OSA. Aspirate cytology with ALP staining was a simple, fast, safe and accurate diagnostic test for the evaluation of suspected OSA lesions in dogs.

The use of culture systems for the study of oligodendrocyte development and injury: The erbB2 gene is required for the development of terminally differentiated spinal cord oligodendrocytes

  • Park, Song-Kyu;Kim, Hwan-Mook;Vartanian, Timothy
    • Proceedings of the Korea Environmental Mutagen Society Conference
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    • 2002.05a
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    • pp.14-23
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    • 2002
  • Development of oligodendrocytes and the generation of myelin internodes within the spinal cord depends on regional signals derived from the notochord and axonally derived signals. Neuregulin (NRG)-1, localized in the floor plate as well as in motor and sensory neurons, is necessary for normal oligodendrocyte development. Oligodendrocytes respond to NRGs by activating members of the erbB receptor tyrosine kinase family. Here, we show that erbB2 is not necessary for the early stages of oligodendrocyte precursor development, but is essential for proligodendroblasts to differentiate into galactosylcerebroside-positive (GalC+) oligodendrocytes. In the presence of erbB2, oligodendrocyte development is normal. In the absence of erbB2 (erbB2-/-), however, oligodendrocyte development is halted at the proligodendroblast stage with a >10-fold reduction in the number of GalC+ oligodendrocytes. ErbB2 appears to function in the transition of proligodendroblast to oligodendrocyte by transducing a terminal differentiation signal, since there is no evidence of increased oligodendrocyte death in the absence of erbB2. Furthermore, known survival signals for oligodendrocytes increase oligodendrocyte numbers in the presence of erbB2, but fail to do so in the absence of erbB2. Of the erbB2-/- oligodendrocytes that do differentiate, all fail to ensheath neurites. These data suggest that erbB2 is required for the terminal differentiation of oligodendrocytes and for development of myelin.

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Avoiding Automatic Android App Analysis by Detecting Random Touch Generation (무작위 터치 발생 탐지를 이용한 안드로이드 앱 자동 분석 회피에 관한 연구)

  • Yun, Han Jae;Lee, Man Hee
    • Convergence Security Journal
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    • v.15 no.7
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    • pp.21-29
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    • 2015
  • As the number of malicious Android applications increases rapidly, many automatic analysis systems are proposed. Hoping to trigger as many malicious behaviors as possible, the automatic analysis systems are adopting random touch generation modules. In this paper, we propose how to differentiate real human touches and randomly generated touches. Through experiments, we figured out that the distance between two consecutive human touches is shorter than that of random generation module. Also we found that the touch speed of human is also limited. In addition, humans rarely touch the outer area of smartphone screen. By using statistics of human smartphone touch, we developed an algorithm to differentiate between human touches and randomly generated touches. We hope this research will help enhance automatic Android app analysis systems.

A Study on Differentiate Performance of Public Assistance Program in Rural Community (농촌지역 공공부조사업의 차별성 반영에 관한 연구)

  • Kim, In
    • Korean Journal of Social Welfare
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    • v.42
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    • pp.107-138
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    • 2000
  • Today, the public assistance program in Korea is provided mainly for the livelihood protection beneficiary in urban area. The fact that the urban community-centered program is also applied to the livelihood protection beneficiary in rural area brings about some problems in fitness and effectiveness of resource distribution. The purpose of my study is to present my opinion that the public assistance program for the rural community should be put in practice after being fully distinguished from the urban program for the effective distribution of limited social welfare resources to insure the minimum standard of living and seek the self-support contribution which is the purpose of the public assistance program. The subject for this study were livelihood protection beneficiaries living in both rural and urban area. And the study was carried out in this parts: first, the way of life in them, second, the contents of 6 main public assistance programs being carried out. Total number of the livelihood protection beneficiaries are 279 case: 143 case from 15 Dong in 5 cities, and 136 case from 15 Myun in 5 counties. And the social worker who are performing the public assistance programare consisted of 50 case: 25 case from 5 Dong in 5 cities, and 25 case from 5 Myun in 5 counties. This research reach the result that the differentiate performance of the public assistance program in rural community would be an effective device for self-support to be freed from the vicious circle of poverty.

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Power Swing Detection Using rms Current Measurements

  • Taheri, Behrooz;Razavi, Farzad
    • Journal of Electrical Engineering and Technology
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    • v.13 no.5
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    • pp.1831-1840
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    • 2018
  • During a power swing, distance relays may mistakenly spread fault throughout the power grid, causing a great deal of damage. In some cases, such mistakes can cause global outages. For this reason, it is critical to make a distinction between power swings and faults in distance relays. In this paper, a new method is proposed based on RMS measurement to differentiate between faults and power swings. The proposed method was tested on two standard grids, demonstrating its capability in detecting a power swing and simultaneous fault with power swing. This method required no specific configurations, and was independent of grid type and zoning type of distance relays. This feature in practice allows the relay to be installed on any grid with any kind of coordination. In protective relays, the calculations applied to the microprocessor is of great importance. Distance relays are constantly calculating the current RMS values for protection purposes. This mitigates the computations in the microprocessor to detect power swings. The proposed method was able to differentiate between a fault and a power swing. Furthermore, it managed to detect faults occurring simultaneously with power swings.