• Journal of Nutrition and Health
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• v.28 no.7
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• pp.629-635
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• 1995

Obese children have increaed in Korean in recent years as socieconomic status have got more higher than past years. Obese children have many health problems and some kinds of complications. Obese patients who have fatty liver with abnormal liver function should be managed with weight control. This study was intended to investigate the effect of weight control on hepatic abnormalities of obese children with fatty liver. We managed 6 obese children who had fatty liver with abnormal liver finction for weight control containing behavior modification, diet and exercise during 3 months. After 3 months, we compared body weight, liver function test, dietary intake and exercise. Body mass index(BMI) showed significant decrease from 28.1$\pm$2.3kg/$m^2$ to 26.2$\pm$1.7kg/$m^2$ (p<0.01). Aspartate aminotransferase(AST) showed significant improvement from 56$\pm$15IU/l(p<0.01). Alanine aminotransferase(ALT) also showed significant improvement from 108$\pm$38IU/l to 33$\pm$9IU/l(p<0.01). Therefore if we can rule out the other causes of hepatic abnormalities in obese children with fatty liver, these patients showed benefit by weight control as it can improve both obesity and liver functions.

• Journal of Korean Public Health Nursing
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• v.21 no.2
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• pp.125-133
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• 2007

Purpose: To identify the compliance level with therapeutic regimen among patients with hypertension residing in rural communities. Method: A descriptive-retrospective research design was employed. One hundred patients with hypertension using 8 Primary Health Care Posts under W Public Health Center were randomly recruited on the basis of being over 35 years of age. After obtaining written consent, the patients underwent direct interviews with a structured questionnaire carried out by 8 public health practitioners. Descriptive statistics and binary logistic regression were utilized. Results: In a binary logistic regression model adjusted for age, sex, education, income, and occupation, those who were receiving medication (OR=5.34), were undergoing a weight control program (OR=4.45), restricted alcohol (OR=9.93), or smoking cessation (OR=25.59) as recommended by medical or health professionals were more compliant (p<.05) while those under a low salt diet, exercise, and stress management were not significant statistically (p>.05). Conclusions: Further research should be conducted to validate these findings so as to facilitate the development of nursing intervention strategies for improving the compliance of hypertensive patients in respect to medication and life style modification.

• Korean Journal of Community Nutrition
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• v.9 no.1
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• pp.81-89
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• 2004

A systematic review and meta-analysis of the literatures was conducted to evaluate the effectiveness of nutrition intervention by dietitian. The 31 studies that were all randomized controlled trials, were identified from computerized search of published researches on MEDLINE, Embase database until January, 2003 and review of reference lists. The main search terms were the combination “dietitian”, “dietary intervention”, “nutrition intervention” or “nutritional intervention” and “effectiveness”. The subgroup analysis was performed by the publication year, quality score, type of disease, content of intervention, intervention provider, type of intervention (nutritional counseling and education/nutrilion counseling and education + diet modification), method of intervention (individual/group/individual + group) and follow-up period. Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. The meta-analysis of 31 studies based on the random effect model showed that the medical nutrition therapy was significantly effective in treating the diseases (effect size 0.1715 : 95% confidence interval 0.0938-0.2491). This study showed the clear evidence of the effectiveness of nutrition intervention through the meta-analysis. So the nutrition intervention by dietitian should be recommended and recognized as the effective therapy of treating the diseases. Also the nutrition intervention should be conducted regularly to maintain the effectiveness of the nutrition intervention. The nutrition intervention was significantly effective in treating the diseases on the random effect model (effect size 0.1715 : 95% confidence interval 0.0938-0.2491).

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.299-302
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• 2013

Methylenetetrahydrofolate reductase (MTHFR) has been reported to be associated with DNA methylation, an epigenetic feature frequently found in gastric cancer. We conducted a case-control study to explore the association of MTHFR C677T polymorphisms with gastric cancer risk and its relation with the DNA methylation of COX-2, MGMT, and hMLH1 genes. Genotyping of P16, MGMT and HMLH1 was determined by methylation-specific PCR after sodium bisulfate modification of DNA, and genotyping of MTHFR C677T was conducted by TaqMan assays using the ABI Prism 7911HT Sequence Detection System. Folate intake was calculated with the aid of a questionnaire. Compared with the MTHFR 677CC genotype, the TT genotype was significantly associated with 2.08 fold risk of gastric cancer when adjusting for potential risk factors. Individuals who had an intake of folate above $310{\mu}g$/day showed protective effects against gastric cancer risk. The effect of MTHFR C677T polymorphisms on the risk of gastric cancer was modified by folate intake and methylation status of MGMT (P for interaction <0.05).

• Journal of Korean Academy of Nursing
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• v.38 no.4
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• pp.533-540
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• 2008

Purpose: This study was designed to examine the effects of a weight control program on body weight and the sense of efficacy for control of dietary behavior in psychiatric inpatients. Methods: A quasi-experimental design was used. Data were collected from March 1 to September 30, 2007. Female mentally ill patients in closing psychiatry ward of H University Hospital participated in the study (16 persons in the experimental group and 13 in the control group). Results: The weight control program including diet therapy, exercise, education and behavior modification therapy decreased the rate of weight gain in female mentally ill patients taking atypical anti psychotics, and effectively increased a sense of efficacy for control of dietary behavior. Conclusion: Weight control program had a positive effect as a nursing intervention to decrease obesity and to increase the sense of efficacy for control of dietary behavior of psychiatric inpatients in psychiatric inpatients.

• Journal of muscle and joint health
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• v.20 no.1
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• pp.31-42
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• 2013

Purpose: The purpose of this study was to develop an evidence-based dysphagia nursing care protocol for nursing home (NH) residents in Korea. Methods: The protocol was developed based on international guidelines and literatures. After testing content validity by experts, the protocol was applied to the intervention group (n=35) for 4 weeks at one NH in December, 2011, whereas the control group (n=34) received routine care. Results: The protocol was composed of one-page algorithm and detailed guidelines. Algorithm pathway was organized in 3 parts, including screening dysphagia risk, grouping by dysphagia risk level, and assigning nursing care into each group. The nursing care included positioning, oral care, meal time care, diet modification, providing exercise and maneuver, and checking dysphagia signs and symptoms. The experts verified the content validity. Protocol was revised to fit NH practice after the participant observation. Clinical validity was established upon evaluating usefulness, appropriateness, and convenience of the protocol by NH nurses. Dysphagia risk of the intervention group was significantly decreased. Conclusion: Developed protocol will improve the quality of dysphagia care in nursing homes as it can serve as a consistent and integrated standard for nursing care of residents with dysphagia.

• Asian-Australasian Journal of Animal Sciences
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• v.8 no.6
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• pp.533-555
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• 1995

Direct-fed microbials (DFM) have been used to enhance milk production in lactating cattle and to increase feed efficiency and body weight gain in growing ruminants. Primary microorganisms that have been used as DFM for ruminants are fungal cultures including Aspergillus oryzae and Saccharomyces cerevisiae and lactic acid bacteria such as Lactobacillus or Streptococcus. Attempts have been made to determine the basic mechanisms describing beneficial effects of DFM supplements. Various modes of action for DFM have been suggested including : stimulation of ruminal microbial growth, stabilization of ruminal pH, changes in ruminal microbial fermentation pattern, increases in digestibility of nutrients ingested, greater nutrient flow to the small intestine, greater nutrient retention and alleviation of stress, however, these responses have not been observed consistently. Variations in microbial supplements, dosage level, production level and age of the animal, diet and environmental condition or various combinations of the above may partially explain the inconsistencies in response. This review summarizes production responses that have been observed under various conditions with supplemental DFM and also corresponding modification of ruminal fermentation and other changes in the gastrointestinal tract of ruminant animals.

• Korean Journal of Adult Nursing
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• v.23 no.2
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• pp.146-159
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• 2011

Purpose: The purpose of this study was to investigate the effects of the internet based coaching program for obesity management on weight control related knowledge, self-efficacy, eating habits, physical activity and obesity related physiological indexes in hypertensive patients. Methods: The study design was non-equivalent control group pre-test-post-test design. A total of 43 subjects were overweight or obese hypertensive patients aged 30 or older, who were divided into experimental group (n=23) and control group (n=20). This program lasting 12 weeks consisted of a weight control related education, internet based individual coaching for diet, exercise and behavior modification, offering internet community and health counseling. The variables were measured three times (before the treatment, after 6 weeks, and after 12 weeks) and the collected data were analyzed by SPSS/WIN 17.0 program. Results: The experimental group had significantly improved weight control related knowledge, self efficacy, eating habits, body composition, and systolic blood pressure with time. Conclusion: The internet based coaching program was effective in improving obesity management, also this program will help to prevent cardiovascular disease of obese hypertensive patients.

• Journal of the East Asian Society of Dietary Life
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• v.16 no.3
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• pp.292-298
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• 2006

Modification of the diet during childhood and adolescence may be an effective strategy for maximizing the peak bone mass. Many supplementation studies have suggested a positive effect of the increased vitamin D intake on the bone mineral status in the elderly. However to date all studies have been conducted on old men and postmenopausal women. The aim of this study was to examine the effects of vitamin D supplementation on the bone mineral density and bone mineral content in growing rats. Twenty Sprague-Dawley female rats were divided into two groups; Control, and vitamin D supplementation. The bone mineral density(BMD) and bone mineral content(BMC) were measured using PIXImus in the spine and femur. Vitamin D supplementation did not affect the level of weight gain, mean food intake and food efficiency ratio. In addition, vitamin D supplementation had no added effect on the spine and femur BMD, and BMC. There were no significant differences in the spine BMD/weight and BMC/weight between the groups, but the spine BMD/weight and BMC/weight was 11 % higher in the vitamin D supplementation group. The femur BMD/weight and femur BMC/weight were significantly higher in the vitamin D supplementation group 9 weeks after the experiment. These results provide evidence of the beneficial effects of vitamin D supplementation on the BMD during the growth period.

• Journal of Korean Medicine for Obesity Research
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• v.8 no.1
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• pp.101-108
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• 2008

Objective The purpose of this study is to evaluate the effectiveness of obesity management program with herbal medication(Changbudodamtanggamibang) on an obese female patient with oligomenorrhea resulted from polycystic ovary syndrome. Methods I applied herbal medication(Changbudodamtanggamibang), acupuncture, auricular acupuncture, electrolipolysis, low calorie diet, aerobic exercise, behavioral modification therapy and fumigation therapy to her. Results Her weight decreased from 64.3kg to 54.0kg, BMI from $26.4kg/m^2$ to $22.2kg/m^2$, PBF from 38.9% to 29.6%, and WHR from 0.89 to 0.82. Menstrual period was normalized from 60days to 34days. ConclusionThese results provides an evidence that obesity management program with herbal medication(Changbudodamtanggamibang) is effective on oligomenorrhea of an obese female patient with polycystic ovary syndrome.