• Journal of Ginseng Research
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• 제44권2호
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• pp.238-246
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• 2020

Background: Dietary fat has been suggested to be the cause of various health issues. Obesity, hypertension, cardiovascular disease, diabetes, dyslipidemia, and kidney disease are known to be associated with a high-fat diet (HFD). Obesity and associated conditions, such as type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD), are currently a worldwide health problem. Few prospective pharmaceutical therapies that directly target NAFLD are available at present. A Traditional Chinese Medicine, ginseng-plus-Bai-Hu-Tang (GBHT), is widely used by diabetic patients to control glucose level or thirst. However, whether it has therapeutic effects on fat-induced hepatic steatosis and metabolic syndrome remains unclear. Methods: This study was conducted to examine the therapeutic effect of GBHT on fat-induced obesity, hepatic steatosis, and insulin resistance in mice. Results: GBHT protected mice against HFD-induced body weight gain, hyperlipidemia, and hyperglycemia compared with mice that were not treated. GBHT inhibited the expansion of adipose tissue and adipocyte hypertrophy. No ectopic fat deposition was found in the livers of HFD mice treated with GBHT. In addition, glucose intolerance and insulin sensitivity in HFD mice was also improved by GBHT. Conclusion: GBHT prevents changes in lipid and carbohydrate metabolism in a HFD mouse model. Our findings provide evidence for the traditional use of GBHT as therapy for the management of metabolic syndrome.

• 가정∙방문간호학회지
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• 제16권1호
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• pp.49-58
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• 2009

Purpose: This study aimed to clarify the needs for hospital-based home care nursing medical services in elder care institutions by analyzing the details and frequency of medical services provided by, and the needs for, hospital based home care nursing in select institutions in Korea. Methods: Seventy-seven staffs at elderly care institutions located throughout the country completed self-report questionnaires between February 1 and May 31, 2009. SPSS ver. 14.0 was used for data analysis regarding frequency and percentage, mean and standard deviation. Results: Forty-eight hospital-based home care nursing medical services in eight domains were identified as being needed in elderly care institutions. The most commonly used medical services were providing instruction in oral drug administration, checking drug beneficial/adverse effects, and administering blood glucose test, while the most needed medical services requiring hospital based home care nursing were complex pressure ulcer care, followed by diabetic foot ulcer management and nutrient injection. Conclusion: The present results should provide fundamental data for better healthcare services with hospital based home care nursing at elderly care institutions as part of a 'win-win' strategy through which medical expenses are reduced, insurance costs are kept stable, and safe and high-quality medical services are provided for residents of elder care institutions. Political decisions intended to promote visits by hospital based home care nurses to elder care institutions would be a prudent course.

• Biomolecules & Therapeutics
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• 제28권1호
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• pp.110-118
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• 2020

Migration presents a substantial social and public health issue. However, it is unclear whether diabetes is worse among Asian migrants than natives of South Korea over time. This longitudinal study investigated the nationwide population, including 2,680,495 adults aged 20 years and older (987,214 Asian migrants and 1,693,281 natives), who received health check-ups, using the Korean National Health Insurance Service data (2009-2015). Joinpoint regression was used to estimate the annual percentage change of diabetes, and multivariable logistic regression was used to examine differences in incident type 2 diabetes between Asian migrants and natives adjusting for age, sex, economic status, body mass index, smoking status, any alcohol use, and physical activity. The age-adjusted prevalence of diabetes increased among native men (from 8.8% in 2009 to 9.7% in 2015, APC=1.64, p<0.05) compared to Asian migrant men, and the age-adjusted prevalence of diabetes increased among native women (from 6.0% in 2009 to 6.7% in 2015, APC=1.88, p<0.05) compared to Asian migrant women. In the multivariate analyses, Asian migrants were less likely to get type 2 diabetes than natives (odds ratio, 0.82; 95% CI, 0.78 to 0.86) between the first and last health check-ups. However, the odds ratio for developing type 2 diabetes was 1.15 (95% CI, 1.10 to 1.20) among low-income levels compared to high-income levels, regardless of whether they were Asian migrants or natives. The results could help to establish a new strategy for prevention, treatment, and management of diabetes among the Asian population.

• Journal of Nutrition and Health
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• 제41권4호
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• pp.317-326
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• 2008

This study was performed to investigate the effects of alcohol drinking frequency and foods consumed along with alcohol on anthropometry, serum lipid levels, and blood pressures in 73 male type 2 diabetic patients aged 30-59 years old. Dietary data for usual intake were obtained from the subjects by the 3-day food records. Separate data for foods consumed along with alcohol as accompaniment were collected and analyzed for energy and nutrient intakes. Both alcohol drinking frequency and/or the amount of energy consumed from accompaniment influenced clinical data as well as anthropometric measurements. The serum total- and HDL-cholesterol, triglyceride levels and systolic blood pressure were significantly higher in the group with a drinking frequency of ${\geq}$ 2/week than that of ${\leq}$ 1/week and also in the group whose daily energy intake from accompaniment was greater than the median (106.6 kcal/d) than that below the median. When the data were adjusted for age, amount of energy intake from alcohol and diet, the anothropometric measurements such as body weight, BMI, waist circumference were significantly higher in patients whose energy intake from accompaniment was greater than the median than that below the median. The results of our study suggest that both alcohol drinking frequency and the energy intake from foods consumed along with alcohol as accompanements are important contributing factors to clinical and anthropometric parameters whose associations with the cardiovascular complications are well established in patients with diabetes mellitus.

• Neonatal Medicine
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• 제28권1호
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• pp.41-47
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• 2021

Neonatal diabetes mellitus can be categorized as transient, permanent, or syndromic, and approximately half of the cases are transient. We present a case involving a term newborn who showed overt progression of transient neonatal diabetes mellitus, with complete remission within 6 months. On the second day of life, the patient presented with tachypnea, hyperglycemia, and decreased serum levels of C-peptide and insulin. Continuous subcutaneous infusion of insulin and continuous glucose monitoring were well tolerated. The patient showed a normal growth pattern, with no hyperglycemic or hypoglycemic episodes at 6 months of age. As it is rare and often asymptomatic, hyperglycemia may be attributed to various factors, including intrauterine environment, perinatal stress, and diverse genetic background. Therefore, consistent blood glucose monitoring and prompt early insulin therapy are crucial for any term newborns with persistent hyperglycemia, to prevent further diabetic complications. Moreover, continuous subcutaneous insulin infusion and the utilization of continuous glucose monitoring devices are the most effective and practical management strategies.

• 한국콘텐츠학회논문지
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• 제21권9호
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• pp.714-722
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• 2021

본 연구에서는 가상현실을 이용한 VR 기본간호술 교육 콘텐츠를 제안하고자 하였다. 핵심기본간호술 20가지 중 간이혈당검사와 인슐린피하주사 항목은 간호술 항목에서 빈번히 수행하는 기본간호술 중 하나이며, 당뇨환자들에게 자가관리 교육을 할 때도 사용할 수 있는 항목이다. 본 연구는 이 항목을 가지고 학습자의 체험을 중심으로 가이드, 미션, 피드백의 3단계로 나누어 몰입형 VR기반 핵심기본간호술 콘텐츠를 설계하였다. 이 콘텐츠에서는 실제 간호술처럼 콘트롤러를 사용하지 않고 손가락 관절인식을 통해 손의 움직임을 트랙킹하여 몰입하며 훈련할 수 있다. 이 연구는 임상 수행 능력 향상을 도울 수 있는 VR 간호술 교육 콘텐츠 개발에 도움이 될 것이다.

• 디지털융복합연구
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• 제16권11호
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• pp.363-372
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• 2018

본 연구의 목적은 대사증후군이 당뇨병으로 확대되는 것을 방지하는데 이용할 수 있는 구체적인 분류 규칙을 도출하는 것이다. 좀 더 구체적으로 말하면, 대사증후군을 앓고 있는 사람들을 당뇨병이 없는 사람 (class 0)과 당뇨병이 있는 사람(class 1)으로 구별해 내는 분류하는 규칙을 찾는 것이다. 본 연구는 국민건강영양조사 데이터를 수집하여 데이터 전처리 과정들을 거친 후 의사결정나무를 구축하였다. 생성된 의사결정나무로부터 유용한 5개의 분류 규칙을 도출하였는데, 이들의 평균 분류 정확도는 75.8%이었다. 또한, 생성된 의사결정나무로부터 고혈압 여부와 허리둘레가 class 0 그룹과 class 1 그룹으로 분류하는데 있어서 중요한 요인임을 알 수 있었다. 이번 연구 결과는 의사들이 향후 대사증후군 환자가 당뇨환자가 되지 않도록 치료하는데 좋은 지침이 될 것으로 기대된다.

• 산업융합연구
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• 제20권3호
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• pp.63-71
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• 2022

본 연구는 지역사회 당뇨병 환자를 대상으로 자가간호에 대한 기능성 게임을 접목한 모바일 헬스케어 앱('롤리폴리 160')의 효과를 검증하고자 시도하였다. 개발된 '롤리폴리 160'의 품질을 자체 평가한 후, G광역시 병의원과 보건소에서 당뇨 진료를 받은 120명의 당뇨환자를 모집하였다. 동구에 거주하는 60명의 당뇨환자를 실험군으로 배치하여 '롤리폴리 160'을 12주 동안 하루 5-10 분, 일주일에 5번 이상 사용하도록 하였고. 서구에 거주하는 60명 대조군은 실험전 집단강의를 받고, 12주 동안 스스로 당뇨관리를 하도록 하였다. 두 군 모두에게 실험 전후 자가간호 수행을 측정하였다. 수집 된 데이터는 빈도분석, 기술통계, t-test, 교차분석하였다. 연구결과 실험군의 약물요법, 발관리, 운동요법, 식이요법 자가간호 점수가 사전보다 사후에 통계적으로 유의미하게 증가하였다. 반면, 대조군의 식이요법 자가간호 점수는 사전보다 사후에 통계적으로 유의미하게 감소한 것으로 나타났다. 따라서 향후 '롤리폴리 160'는 당뇨환자의 자가간호를 위한 간호중재 프로그램으로 활용될 수 있을 것이다.

• 대한간호학회지
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• 제53권2호
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• pp.167-176
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• 2023

Purpose: Despite the high prevalence of visual impairment caused by diabetic retinopathy and nutritional problems among older adults with diabetes, evidence regarding factors related to nutritional risk in this population is limited. Therefore, this study aimed to identify the correlates of nutritional risk among older adults with diabetes, focusing on visual impairment. Methods: This study was a secondary data analysis of the 2020 National Survey of Older Koreans aged 65 years and above. The sample comprised 2,376 older adults with diabetes, and complex sample ANOVA and Rao-Scott chi-square tests were used to compare the groups according to visual impairment. Complex-sample logistic regression analyses were conducted to verify the association between visual impairment and nutritional risk. Results: Older adults with diabetes, who also have severe visual impairment, are more likely to have nutritional risk status than those without impairment after controlling for covariates (odds ratio [OR] = 2.44, 95% confidence interval [CI] 1.16~5.13). Among the covariates, depression (OR = 3.58, 95% CI 2.60~4.94), dependent activities of daily living status (OR = 2.79, 95% CI 1.60~4.86), and experience of hospitalization during the past year (OR = 2.51, 95% CI 1.57~4.03) were strongly associated with nutritional risk. Conclusion: Severe visual impairment increases the nutritional risk among older adults with diabetes. Therefore, it is essential to prevent visual impairment due to exacerbation of diabetes through appropriate management. Additionally, tailored nutritional interventions for visually impaired older adults with diabetes that consider visual characteristics are required.

• 산업융합연구
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• 제21권6호
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• pp.91-97
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• 2023

본 연구는 제8기 국민건강영양조사 자료를 이차 분석한 서술적 조사연구이다. 한국의 30~49세 성인 중 당뇨병 유병자 총 300명의 당뇨병 유병률과 인지율을 분석하고 이에 영향을 미치는 요인을 확인하고자 시도되었다. 자료 분석은 SPSS 25.0 program을 이용하여 복합표본 빈도와 백분율, χ²-test, 로지스틱 회귀분석을 실시하였다. 당뇨병 유병자 중 당뇨병임을 인지한 자는 171명(57.0%)이었으며 인지에 영향을 미치는 요인은 성별, 교육수준, BMI, 주관적 건강상태, 심혈관질환, 부계 및 모계 가족력이었다. 본 연구의 결과를 토대로 비교적 젊은 30~49세 당뇨 유병률을 감소시키고 유병자들의 인지율을 높이는 정책 및 중재 프로그램을 수립하는데 기초자료로 활용될 수 있을 것이다.