• 한국한의학연구원논문집
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• 제10권1호
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• pp.107-117
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• 2004

Each Local public heal public health service center is in difficult situation on programing and performing of local public health service. The purpose of research is to inquire of the present state of local public health service and search long-term developmental methods. The first, in order to accomplish this purpose, I distributed questionnaires to Korean medical doctors, who are worked in public health service center and researched that. The second, based on these findings, I proposed planning for upcoming project for activating local public health service on Korean medicine.

• International Journal of Human Ecology
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• 제6권1호
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• pp.41-59
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• 2005

In this paper, the e-grocery sector of the U.S. is used as an illustrative example of how to assess consumers' demands for customer relationship management and to investigate whether these demands coincide with effective Customer Relationship Management (CRM) strategies suggested by academic researchers and provided by practitioners. Surveys evaluating the perceived importance of CRM items were administered accordingly. The findings show that, overall, consumers' did not differ considerably to the experts. The results of descriptive analyses showed that academicians had a more closely in-lined view with consumers than did practitioners. Although not statistically significant, practitioners perceived loyalty programs to be more important than did consumers or academicians. This might suggest that loyalty programs are primarily serving as a way of data mining, and are thus failing to provide benefits to consumers. Overall, items related to technology deployment were perceived to be more important by practitioners than consumers or academicians.

• 대한가정학회지
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• 제44권6호
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• pp.103-111
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• 2006

The purpose of the study was to examine the agreement between parent and adolescent reports on parenting behaviors. The participants were 196 father-mother-adolescent triads. Results indicated that there were significant differences in reports of parenting behaviors between parents and adolescents. Generally, parents reported higher respect, disciplines and attention than their adolescents did. However, there were low to high agreements between parental report and adolescent report on parenting behaviors. The degree of those agreements varied by adolescent's developmental stage, birth order and mother's education. The findings suggested that differences in agreements between parent and adolescent reports on parenting behaviors might not be random and the agreements should be addressed in terms of specific sample characteristics.

• Neonatal Medicine
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• 제18권1호
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• pp.1-5
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• 2011

Coagulation involves the regulated sequence of proteolytic activation of a series of proteins to achieve appropriate and timely hemostasis in an injured vessel. In the non-pathological state, the inciting event involves exposure of circulating factor VIIa to extravascularly expressed tissue factor, which brings into motion the series of steps which results in cell based model of coagulation. In the new concepts of coagulation system, initiation, amplification and propagation steps are involved to converse of fibrinogen to fibrin. The precisely synchronized cascade of events is counter-balanced by a system of anticoagulant mechanisms. Developmental hemostasis refers to the age-related changes in the coagulation system that are most marked during neonate and childhood. An understanding of these changes in crucial to the accurate diagnosis of hemostatic abnormalities in neonate and children. This review aims to elucidate the main events within the coagulation cascade as it is currently understood to operate in vivo, and also a short review of the anticoagulants as they relate to this model. Also this paper describes the common pitfalls observed in the clinical data related to the coagulation system in neonate to children.

• Reproductive and Developmental Biology
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• 제39권3호
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• pp.69-76
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• 2015

In a conventional sense, dried-spermatozoa are all dead and motionless due to the lost of their natural ability to penetrate oocytes both in vivo and in vitro. However, their nuclei are completely able to contribute to normal embryonic development even after long-term preservation in a dried state when the dried-spermatozoa are microinjected into the oocytes. In this sense, dried spermatozoa must still be alive. Thus, defining spermatozoa as alive or dead seems rather arbitrary. Several drying method of sperm including freeze-drying, evaporative/convective-drying and heat-drying were represented in this review. Although the drying protocol reported here will need further improvement, the results suggest that it may be possible to store the male genetic resources.

• Molecules and Cells
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• 제41권10호
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• pp.889-899
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• 2018

Intrinsically disordered proteins (IDPs) are highly unorthodox proteins that do not form three-dimensional structures under physiological conditions. The discovery of IDPs has destroyed the classical structure-function paradigm in protein science, 3-D structure = function, because IDPs even without well-folded 3-D structures are still capable of performing important biological functions and furthermore are associated with fatal diseases such as cancers, neurodegenerative diseases and viral pandemics. Pre-structured motifs (PreSMos) refer to transient local secondary structural elements present in the target-unbound state of IDPs. During the last two decades PreSMos have been steadily acknowledged as the critical determinants for target binding in dozens of IDPs. To date, the PreSMo concept provides the most convincing structural rationale explaining the IDP-target binding behavior at an atomic resolution. Here we present a brief developmental history of PreSMos and describe their common characteristics. We also provide a list of newly discovered PreSMos along with their functional relevance.

• 한국문헌정보학회지
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• 제39권2호
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• pp.259-286
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• 2005

이 논문은 현재 우리 학교도서관의 변화 과정에서 나타나는 여러 가지 영향 요소를 리더십의 측면에서 규정하고 그 성격과 상황에 대해 탐구하였다. 현재 우리나라 학교도서관의 변화 과정에서 작용하는 계기와 동기를 현장 리더십, 정책 리더십, 학문 리더십으로 구분하여 그 역할과 실체를 다각도로 조명하였으며 학교도서관의 지속적이며 안정적인 발전을 위해 각 리더십의 개선 사항과 요건을 제안하였다.

• International Journal of Naval Architecture and Ocean Engineering
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• 제11권1호
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• pp.510-520
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• 2019

To investigate the morphology characteristics of air layer in the air cavity, a numerical method with the combination of RANS equations and VOF two-phase-flow model is proposed for a plate with air cavity. Based on the model above, the dynamic and developmental process of air layer in the air cavity is studied. Numerical results indicate that the air layer in the plate's air cavity exhibits the dynamic state of morphology and the wavelength of air layer becomes larger with the increasing speed. The morphology of air layer agrees with the Froude similarity law and the formation of the air layer is not affected by the parameters of the cavity, however, the wave pattern of the air layer is influenced by the parameters of the cavity. The stable air layer under the air cavity is important for the resistance reduction for the air layer drag reduction.

• 한국발생생물학회지:발생과생식
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• 제25권1호
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• pp.55-57
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• 2021

Samples were collected from the subtidal region of Jumunjin on the eastern coast of Korea in July 2020. A total of 338 mussels of shell height (SH) 20.8-149.8 mm were used for sex ratio analysis. The sex ratio (F:M) in the same population of mussel Mytilus coruscus was approximately 1:0.7. The sex ratio according to the class of SH was different. The sex reversal pattern of M. coruscus appears to go from male → female → male → female, and as such is determined to be sequential hermaphrodites.

• Molecules and Cells
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• 제45권2호
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• pp.53-64
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• 2022

Three-dimensional cultures of human neural tissue/organlike structures in vitro can be achieved by mimicking the developmental processes occurring in vivo. Rapid progress in the field of neural organoids has fueled the hope (and hype) for improved understanding of brain development and functions, modeling of neural diseases, discovery of new drugs, and supply of surrogate sources of transplantation. In this short review, we summarize the state-of-the-art applications of this fascinating tool in various research fields and discuss the reality of the technique hoping that the current limitations will soon be overcome by the efforts of ingenious researchers.