• Title/Summary/Keyword: developmental difference

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Effect of Serum and Serum Free Media on the Developmental Competence of OPU Derived Bovine IVP Embryo

  • Choi, Byung-Hyun;Park, Bun-Young;Kong, Rami;Son, Mi-Ju;Park, Chan-Sang;Shin, Nyeon-Hak;Cheon, Hye-Young;Yang, Yeong-Rok;Lee, Jin-Woo;Jin, Jong-In;Kong, Il-Keun
    • Journal of Animal Reproduction and Biotechnology
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    • v.34 no.4
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    • pp.305-310
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    • 2019
  • Embryos produced with serum show the alterations in their ultrastructure, impaired compaction, abnormal blastulation, aberrant mRNA expression profiles and large calf syndrome with greater incidences of stillbirths and deaths after birth. The aim of the present study was to describe in vitro embryo production by analyzing embryo production, fetal production and pregnancy rate in free-serum medium. The OPU-IVP data used in this study from 2016. Approximately, sixteen cows (Hanwoo), which belonged to the Institute of Gyeongsang National University, were used. Two experimental group is used in this study. Serum groups were conducted in March to July and free-serum group was conducted in September to December. The recovered cumulus-oocyte complexes were morphologically classified to four grades based on the compaction of cumulus cells layers and homogeneity of the cytoplasm. The number of oocyte was significantly greater in serum groups than that in free-serum groups (29.61 ± 0.63 vs. 15.6 ± 0.62; p < 0.05). Between serum and free-serum groups indicate that average of 1st and 2nd grade oocytes were no difference (2.38 ± 1.67 vs. 2.38 ± 1.48; p > 0.05), but number of 3rd and 4th grade oocytes were greater in serum groups than that in free-serum groups (7.31 ± 7.64 vs. 5.60 ± 6.29; p < 0.05). Embryo cleaved competence was higher in rate in free-serum groups than that in serum groups (62.1% vs. 58.3; p < 0.05). However, blastocyst developmental rate was no difference between serum and free-serum groups (33.1% vs. 43.5%; p < 0.05). 986 recipients were used for embryo transfer. Pregnancy rate was indicated that between serum and free-serum group was no difference (54.6% vs. 56.3%; p < 0.05). In conclusion, we developed the free-serum system for production of in vitro bovine embryos in order to meet the developmental and qualitative requirements for large scale commercial use.

A Study on the Relationship between Body Function and Prelusive Movement to Falls to Promote Wellness in Chronic Stroke Patients (만성뇌졸중 환자의 웰니스 증진을 위한 신체기능과 낙성전조동작의 관련성 연구)

  • Park, Chang-Sik;Kim, Jin-Young
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.7
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    • pp.181-192
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    • 2021
  • This study was conducted to investigate the effects of a participatory rehabilitation program on sit-rise and rise-to-walk test performances, and perception and motor skills in adults with medically vulnerable individuals and, adults with developmental disabilities in particular. Seventeen adults with developmental disabilities participated in a participatory rehabilitation program using resistance bands and exercise balls, for 60 minutes once weekly over 13 weeks. Their performances were measured before and immediately after the intervention, and 12 weeks after. The findings were as follows. In the sit-rise test, the number of times rising from sitting posture increased after the intervention versus before, but the difference was not statistically significant. In the rise-to-walk test, the performance showed statistically significant difference over time, and the post-hoc test showed a significant effect after the intervention versus before. There was no significant difference in perception and motor skills. In sum, the participatory rehabilitation program positively influenced dynamic balancing related to functional activities but had no significant effect on perception and motor skills, which is related to motor control and motor learning. It is suggested that to increase the participation in community activities, reduce fall risk, and improve dynamic balancing abilities in adults with developmental disabilities, participatory rehabilitation programs should be utilized to promote the physical wellbeing.

A Study on the vocabulary and Problem-Solving Ability of Adolescents with Developmental Disabilities on Leisure and Recreation (발달장애 청소년의 여가 및 레크레이션에 관한 어휘 및 문제해결 능력 연구)

  • Wha-Soo Kim;Eun-Hong Kim;Ji-Won Yang;Ji-Woo Lee;Ju-Hyeon Lee
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.2
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    • pp.107-119
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    • 2024
  • The purpose of this study is to examine and analyze the vocabulary and problem-solving ability characteristics of adolescents with developmental disabilities related to leisure and recreation and use them as basic data in education and support of recreation activities for adolescents with developmental disabilities. The study participants were comprised of adolescents with developmental disabilities, divided into two groups based on their receptive language age: those under 10 years old and those 10 years and older. The results obtained through this study are as follows. First, there was a significant difference in leisure and recreation vocabulary between the two groups according to receptive language age. Second, there was a significant difference in problem-solving ability between the two groups based on their receptive language age. Third, the analysis of the correlation between leisure and recreation vocabulary and problem-solving abilities within each group revealed that the under 10 years old group showed the highest correlation in basic vocabulary and basic problem-solving abilities, while the 10 years and older group exhibited the highest correlation in intermediate and advanced levels of problem-solving abilities. Fourth, the analysis of incorrect responses to leisure and recreation vocabulary showed a high rate of selecting vocabulary related to similar topics as incorrect answers. Additionally, the analysis of overreactions to problem-solving abilities indicated an increasing tendency of incorrect responses in items requiring context comprehension. Additionally, the analysis of incorrect responses to problem-solving abilities indicated a tendency of higher error rates in items requiring context comprehension. The results of this study provide insights for discussing directions in communication-related skills education for the smooth recreation life of adolescents with developmental disabilities. Accordingly, it is expected to be utilized as foundational information for educational and support programs aimed at the successful recreation activities of adolescents with developmental disabilities.

Feeder Independent Culture of Mouse Embryonic Stem Cells

  • Kim, Myoung Ok;Ryoo, Zae Young
    • Reproductive and Developmental Biology
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    • v.36 no.4
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    • pp.291-294
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    • 2012
  • Embryonic stem cell classically cultured on feeder layer with FBS contained ES medium. Feeder-free mouse ES cell culture systems are essential to avoid the possible contamination of nonES cells. First we determined the difference between ES cell and MEF by Oct4 population. We demonstrate to culture and to induce differentiation on feeder free condition using a commercially available mouse ES cell lines.

Sound Intensity Measurement for Characteristics of Two Microphone Arrangements. (두 개의 Microphone 배열 특성에 의한 음향 Intensity 측정)

  • 장호경
    • Proceedings of the Acoustical Society of Korea Conference
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    • 1985.10a
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    • pp.37-42
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    • 1985
  • The errors caused by developmental finite difference approximations in the two microphone acoustic intensity measurement technique are considered in this paper. The frequencies and pressure responses obtained experimentally, are presented for both face to face (FF) and side by side(SS) microphone configurations. The implications of these results by the use of such a cofiguration for two microphone sound intensity measurement are discussed.

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A Study on Social Worker's Perception and Practice of the Right to Self-determination for Person with Developmental Disability: Application of Importance-Performance Analysis(IPA) (발달장애인의 자기결정권에 대한 사회복지사의 인식 및 실천에 관한 연구: 중요도-실행도분석(IPA)의 적용)

  • Lee, Nam-Jeong;Lee, Dong-Young
    • The Journal of the Korea Contents Association
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    • v.20 no.11
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    • pp.624-635
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    • 2020
  • This study focuses on the right to self-determination, which has a higher possibility of infringement on rights, for people with developmental disabilities, who are more vulnerable to rights protection than other types of disabilities, and seeks to obtain implications of the basis for academic discussion and practical strategies. To this end, data were collected through a structured survey on 302 social workers in Seoul, Gyeonggi, and Gangwon area to identify the importance and execution degree of self-determination components of the developmental disabled, and descriptive analysis, differences. analysis, matrix analysis was applied. As a result of the analysis, the importance and performance degree were evaluated at an absolute level lower than the positive level, and the overall average standard execution degree was found to be applied relatively later, and the difference between the two levels was statistically significant. Meanwhile, goal setting and achievement, self-management and regulation, branch recognition and perception, etc. were identified as under-action elements as disparity between importance and performance. Therefore, in order to improve the balanced positivity of social workers and people with developmental disabilities in consideration of the reciprocity of human rights protection, applied behavior analysis, positive behavior support, and individualized service plan based on the application of a person-centered program and self-determination improvement program are applied. Suggestions were made on detailed strategies such as accounting.

Comparison of Cuticular Hydrocarbons of Different Developmental Stages of the Spot Clothing Wax Cicada, Lycorma delicatula (Hemiptera: Fulgoridae) (꽃매미(Lycorma delicatula)의 발육단계별 표피탄화수소 비교)

  • Cho, Sun-Ran;Lee, Jeong-Eun;Jeong, Jin-Won;Yang, Jeong-Oh;Yoon, Chang-Mann;Kim, Gil-Hah
    • Korean journal of applied entomology
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    • v.50 no.3
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    • pp.185-194
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    • 2011
  • Aliphatic cuticular hydrocarbons (CHCs) of different developmental stages of the spot clothing wax cicada, Lycorma delicatula (Hemiptera: Fulgoridae) were analyzed using GC and GC-MS. The numbers of carbons in the major CHCs of each developmental stage 32, 33, 28, 38, 37 in the egg, 1st, 2nd, 3rd, and 4th instar nymphal stages, and adults, respectively. The cuticle of Lycorma delicatula contains mainly methyl-branched 9-methylheptacosane (15.11%) in the egg stage, and a high proportion of n-heptacosane in nymphal stages (15.75, 22.42, 25.04, and 23.11 % in the 1st, 2nd, 3rd and 4th instars, respectively). In contrast, male and female adults had high proportions of n-nonacosane (13.42 and 16.55%). The chemical constituents of CHCs were classified into five groups (n-alkanes, monomethylalkanes, dimethylalkanes, trimethylalkanes, olefins) and group profiles of each developmental stage were compared. Egg surface was composed mainly monomethylalkanes (45.39%), a saturated hydrocarbon. Nymph CHCs consisted primarily of n-alkanes (37.63 to 46.12%). There was a difference between adult male and female CHCs. However, both contained n-alkanes and monomethylalkanes. CHCs with trimethyl or double bonded structure were rare in all stages.

Study of Construct Validity and Test-Retest Reliability of the Korean Version Peabody Developmental Motor Scales-Second Edition (PDMS-2) (한글판 Peabody Developmental Motor Scales-second edition (PDMS-2)의 구성타당도와 검사-재검사 신뢰도)

  • Kim, Bo-Ram;Kim, Kyeong-Mi;Chang, Moon-Young;Hong, Eunkyoung
    • The Journal of Korean Academy of Sensory Integration
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    • v.19 no.3
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    • pp.32-43
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    • 2021
  • Objective : This study aimed to verify the construct validity of the Korean version of the Peabody Developmental Motor Scale-2 (K-PDMS-2) and its test-retest reliability for children with cerebral palsy (CP) and typical children. Method : To ascertain the construct validity, the K-PDMS-2 evaluation was conducted on 42 children with cerebral palsy and 42 typical children of similar age and gender. Construct validity was proved through comparison with standard scores. Ten of the children with CP were re-evaluated after two weeks to determine test-retest reliability. Results : There was a statistically significant difference in gross motor and fine motor development according to five subtests between the group of children with CP and the typical group (p = .000). For test-retest reliability, the correlation coefficient of the total frequency score was .989, representing very high temporal stability. Conclusion : This study confirmed that K-PDMS-2 is an evaluation tool of high reliability and validity, and a potentially useful future measure for domestic clinical sites and research.

Factor Structure of the Korean-Child Behavior Checklist 1.5-5 Dysregulation Profile in Infants and Toddlers With Mental Disorders and the Difference Among Mental Disorders (정신장애 영유아에 대한 K-CBCL 1.5-5 (Korean-Child Behavior Checklist 1.5-5) 조절곤란 프로파일의 요인구조와 정신장애 간 차이검증)

  • Kyung, Hye Min;Ha, Eun Hye
    • Therapeutic Science for Rehabilitation
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    • v.12 no.1
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    • pp.37-49
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    • 2023
  • Object : This study aimed to identify the factor structure of Korean-Child Behavior Checklist 1.5-5 Dysregulation Profile (K-CBCL 1.5-5 DP) in infants and toddlers with mental disorders and verify differences in K-CBCL 1.5-5 DP among the diagnosis groups. Methods : The participants were 265 mothers of infants and toddlers with mental disorders who completed K-CBCL 1.5-5 DP. The data was analyzed using AMOS 25.0 and SPSS 25.0. Results : First, the bifactor model was the most suitable for the factor structure of the K-CBCL 1.5-5 DP. Second, there were significant differences among the diagnosis groups, such as communication disorders, pervasive developmental disorders, emotional disorders, and developmental delays. It was confirmed that the pervasive developmental disorder and emotional disorder groups showed significantly higher dysregulation compared with the communication disorder group. Conclusion : This study confirmed that infants and toddlers had dysregulation problems. Using the bifactor model, the multidimensional nature of the K-CBCL 1.5-5 DP was assessed. It was also meaningful that dysregulation could contribute to onset and deepening of symptoms of pervasive developmental disorders and emotional disorders in infancy.

Estimation of Mandibular Third Molar Development Using the Correlation in Dental Developmental Stages (치아 발육 단계의 상관관계를 이용한 하악 제3대구치 발육 평가)

  • Junyoung Kim;Hyuntae Kim;Teo Jeon Shin;Hong-Keun Hyun;Young-Jae Kim;Jung-Wook Kim;Ki-Taeg Jang;Ji-Soo Song
    • Journal of the korean academy of Pediatric Dentistry
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    • v.50 no.4
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    • pp.373-384
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    • 2023
  • This study aims to confirm the average chronologic age according to the developmental stages of the mandibular canine (L3), first and second premolars (L4, L5), and second and third molars (L7, L8) in children and adolescents, and to confirm the developmental stage of L3, L4, L5, and L7, which can estimate the development of L8. A total of 1,956 digital panoramic radiographs of healthy individuals aged between 6 and 15 years who visited Seoul National University Dental Hospital from January 2019 to December 2020 were selected. The developmental stages of L3, L4, L5, L7, and L8 on both sides were evaluated using the dental maturity scoring system proposed by Demirjian and Goldstein. The average age at which the follicle of L8 was first observed was around 9.34 ± 1.35 years and varied from 6 to 12 years. The possibility of agenesis of L8 was high when no traces of L8 were observed after the following stages: L3, L4, and L5 at the developmental stage F and L7 at the developmental stage E; the age was about 10 years. In estimating the development of L8, when only one tooth was considered, estimation accuracy with L5 was the highest, and there was no significant difference when all four teeth were included. This study showed the age distribution according to the developmental stages of L3, L4, L5, L7, and L8 in children and adolescents and confirmed the developmental stages of L3, L4, L5, and L7, which can be used to estimate the development of L8.