• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.12
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• pp.2917-2923
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• 2015

In spite of a recent trend of container ships becoming larger in size, the current circumstance is that managing reefer containers marine transportation is being mostly dependent upon manpower. Particularly, in the case of bad weather or nighttime, reefer containers are not being monitored due to lack of safety device. For the purpose of reducing such risk, IMO is recommending a system using PLC but the system is not being used. In addition, they are still relying on manpower for control and reliability of freight in transit is decreasing due to lack of information during marine transportation for every subject related to freight as well as shipper. Accordingly, the purpose of this paper is to propose a real-time reefer container management system to effectively control all reefer containers widely being used across the world.

• Journal of Digital Convergence
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• v.12 no.10
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• pp.337-343
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• 2014

The PRT(Personal Rapid Transit) in material or immaterial guided tracks is operated automatically according to the needs of passengers with the optimal non-stop path from the source to the destination. In recent years, the personal rapid transit (PRT) system, which affords superior accessibility and ease of use, has been spotlighted as a new transport system for the future. In this study, a method for vertical lifting of PRT vehicles was proposed to facilitate interlink with other means of transport and thereby improve the efficiency of door-to-door transport. For this purpose, operation control interfaces were designed and experiments were conducted. Programmable Logic Controller (PLC) dedicated for the PRT vertical lift was designed to interface with Operation Control Center (OCC) by Modbus TCP over Ethernet. We implemented a 3D graphical PRT operation simulator which can emulate the mixing operation of the virtual vehicles and the actual vehicles.

• International Journal of Ocean System Engineering
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• v.2 no.3
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• pp.185-194
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• 2012

A Macroscopic combination of two or more distinct materials is commonly referred to as a "Composite Material", having been designed mechanically and chemically superior in function and characteristic than its individual constituent materials. Composite materials are used not only for aerospace and military, but also heavily used in boat/ship building and general composite industries which we are seeing increasingly more. Regardless of the various applications for composite materials, the industry is still limited and requires better fabrication technology and methodology in order to expand and grow. An example of this is that the majority of fabrication facilities nearby still use an antiquated wet lay-up process where fabrication still requires manual hand labor in a 3D environment impeding productivity of composite product design advancement. As an expert in the advanced composites field, I have developed fabrication skills with the use of machinery based on my past composite experience. In autumn 2011, the Korea government confirmed to fund my project. It is the development of a composite sanding machine. I began development of this semi-robotic prototype beginning in 2009. It has possibilities of replacing or augmenting the exhaustive and difficult jobs performed by human hands, such as sanding, grinding, blasting, and polishing in most often, very awkward conditions, and is also will boost productivity, improve surface quality, cut abrasive costs, eliminate vibration injuries, and protect workers from exposure to dust and airborne contamination. Ease of control and operation of the equipment in or outside of the sanding room is a key benefit to end-users. It will prove to be much more economical than normal robotics and minimize errors that commonly occur in factories. The key components and their technologies are a 360 degree rotational shoulder and a wrist that is controlled under PLC controller and joystick manual mode. Development on both of the key modules is complete and are now operational. The Korean government fund boosted my development and I expect to complete full scale development no later than 3rd quarter 2012. Even with the advantages of composite materials, there is still the need to repair or to maintain composite products with a higher level of technology. I have learned many composite repair skills on composite airframe since many composite fabrication skills including repair, requires training for non aerospace applications. The wind energy market is now requiring much larger blades in order to generate more electrical energy for wind farms. One single blade is commonly 50 meters or longer now. When a wind blade becomes damaged from external forces, on-site repair is required on the columns even under strong wind and freezing temperature conditions. In order to correctly obtain polymerization, the repair must be performed on the damaged area within a very limited time. The use of pre-impregnated glass fabric and heating silicone pad and a hot bonder acting precise heating control are surely required.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.9 no.3
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• pp.285-290
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• 2016

In rural area, our farmers confront decreasing benefits owing to imported crops and increased cost. Recently, the government encourage the 6th Industry that merges farming, rural resources, and information and communication technology. Therefor the government makes an investment in supplying 'smart greenhouse' in which a farmer monitor growing crops and environment information to control growing condition. The objective of this study is developing an Moving Monitor and Control System for crops in green House. This system includes a movable sensing unit, a controlling unit, and a server PC unit. The movable sensing unit contains high resolution IP camera, temperature and humidity sensor and WiFi repeater. It rolls on a rail hanging beneath the ceiling of a green house. The controlling unit contains embedded PC, PLC module, WiFi router, and BLDC motor to drive the movable sensing unit. And the server PC unit contains a integrated farm management software and home pages and databases in which the images of crops and environment informations. The movable sensing unit moves widely in a green house and gathers lots of information. The server saves these informations and provides them to customers with the direct commercing web page. This system will help farmers to control house environment and sales their crops in online market. Eventually It will be helpful for farmers to increase their benefits.

• Biomedical Science Letters
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• v.19 no.1
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• pp.9-16
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• 2013

Elevated blood triglyceride (TG) levels correlate with development of atherosclerosis suggesting that TG may promote the development of this disease. During atherosclerosis, TG is taken up by tissue macrophages which result in dramatic changes in various secreted factors. One such factor is the family of matrix metalloproteases (MMP) which are involved in tissue remodeling during both physiological and pathological processes. In this study, we examined the MMP expression profile in PMA-differentiated THP-1 macrophages treated with TG. We found that TG-treated THP-1 macrophages showed decreased expression of MMP-3, MMP-7, MMP-8 and MMP-9 in a time- and dose-dependent manner. In contrast, expression of MMP-1, MMP-2, and MMP-10 remained relatively unchanged after TG treatment. In addition, we found that expression of select MMPs was affected by various inhibitors of signaling pathways. In particular, expression of MMP-3 was slightly recovered by cRAF and PLC signaling pathway inhibitors. These data suggests a possible role of MMPs in macrophages during TG-induced atherosclerosis.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.243-247
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• 2004

The dynamometers which had made in a long time ago could not control the input/output quantity of water minutely and was sensitive to a noise since it was controlled by an analog control method. Therefore, a fully digital controlled system was urgently required to be robust against various noises. In this paper, the new system which can control the amount of circulated water in dynamometer was developed. This system is consisted of an industrial digital type controller and a servo motor. The industrial PLC was used as a main controller for the developed system, and the actuator and servo motor were used to control the inlet and outlet valve independently. The torque signal of load cell was fed back to the main controller to regulate the diesel engines load. Generally, an input/output valve position of the old dynamometer was fixed with a proper situation for an engine output test and the torque was changed according to the time interval. However, the torque value for the dynamometer could not be constantly kept because of the variation of the input water flow and fluid characteristic. Therefore, the automatic control of an inlet and outlet valve should be performed to keep the constant torque. So, the PID control method was applied to solve this problem. Also, the development of a web-based remote control system was described in this paper. This software will give us the convenience of operation, the more efficient operations, and the reduced operator workload for operation of the dynamometer. The application results of the system have been verified at actual diesel engine field.

• Journal of the Korea Society of Computer and Information
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• v.15 no.4
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• pp.91-98
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• 2010

Advances in communications and control technology, the strengthening of the Internet, and the growing recognition of the urgency to reduce the risk and production cost are motivating the development of improvements in the traditional manufacturing industry. In this paper, we developed a remote dust collector bag control system which is a combination of advanced IT and traditional dust collector based on the event. At first, we made the A/D(Analog/Digital) converter using a micro processor because the differential pressure transmission, which is a sensor of the dust collector, produces analog volt data. A/D converter can provide RS-232 communication to connect with Power Line Communication(PLC) modem. And, n-bytes message format was defined for the efficient dust collector bag information transmission from a dust collector to a user. Also, we designed the data types to model the dust collector and the dust collector bag, and they were logically modeled using XML and object-oriented modeling method. In addition to that, we implemented the system for showing the dust collector bag exchange time exactly to users at real-time using various visual user interfaces.

• Journal of the Korean Institute of Intelligent Systems
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• v.22 no.3
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• pp.281-286
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• 2012

In the growing standard of people's lives, we want desire to create eco-friendly water space what is called the Green Technology that is in the limelight. These green space is introduced the cultural contents and we use the water, music, and nature as tool of emotional verbalism. Presently, when we want to make scenario, water landscape scenario is made by director. but these systems have some disadvantages as the cost and limitation of direction. There is a growing interest in the integrated control system based on PC and Internet. In this paper, it is about fountain control system. Previous research area was only one using programmable logic controller or industrial PC. we proposed the development of intelligent green fountain culture system for healthy emotional self-concept. And we made automatic weather sensing system that is designed by the intelligent green fountain culture system to estimate the time-variant system.

• Biomolecules & Therapeutics
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• v.27 no.3
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• pp.311-317
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• 2019

Mast cells are the most prominent effector cells of Type 1 hypersensitivity immune responses. CYC116 [4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl] pyrimidin-2-amine] is under development to be used as an anti-cancer drug, but the inhibitory effects of CYC116 on the activation of mast cells and related allergy diseases have not reported as of yet. In this study, we demonstrated, for the first time, that CYC116 inhibited the degranulation of mast cells by antigen stimulation ($IC_{50}$, ${\sim}1.42{\mu}M$). CYC116 also inhibited the secretion of pro-inflammatory cytokines including TNF-${\alpha}$ ($IC_{50}$, ${\sim}1.10{\mu}M$), and IL-6 ($IC_{50}$, ${\sim}1.24{\mu}M$). CYC116 inhibited the mast cell-mediated allergic responses, passive cutaneous anaphylaxis (ED50, ~22.5 mg/kg), and passive systemic anaphylaxis in a dose-dependent manner in laboratory experiments performed on mice. Specifically, CYC116 inhibited the activity of Fyn in mast cells and inhibited the activation of Syk and Syk-dependent signaling proteins including LAT, $PLC{\gamma}$, Akt, and MAP kinases. Our results suggest that CYC116 could be used as an alternative therapeutic medication for mast cell-mediated allergic disorders, such as atopic dermatitis and allergic rhinitis.

• Biomolecules & Therapeutics
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• v.22 no.3
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• pp.193-199
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• 2014

The aim of this study was to determine whether britanin, isolated from the flowers of Inula japonica (Inulae Flos), modulates the generation of allergic inflammatory mediators in activated mast cells. To understand the biological activity of britanin, the authors investigated its effects on the generation of prostaglandin $D_2$ ($PGD_2$), leukotriene $C_4$ ($LTC_4$), and degranulation in IgE/Ag-induced bone marrow-derived mast cells (BMMCs). Britanin dose dependently inhibited degranulation and the generations of $PGD_2$ and $LTC_4$ in BMMCs. Biochemical analyses of IgE/Ag-mediated signaling pathways demonstrated that britanin suppressed the phosphorylation of Syk kinase and multiple downstream signaling processes, including phospholipase $C{\gamma}1$ ($PLC{\gamma}1$)-mediated calcium influx, the activation of mitogen-activated protein kinases (MAPKs; extracellular signal-regulated kinase 1/2, c-Jun $NH_2$-terminal kinase and p38), and the nuclear factor-${\kappa}B$ ($NF-{\kappa}B$) pathway. Taken together, the findings of this study suggest britanin suppresses degranulation and eicosanoid generation by inhibiting the Syk-dependent pathway and britanin might be useful for the treatment of allergic inflammatory diseases.