• Journal of Food Hygiene and Safety
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• v.12 no.2
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• pp.102-106
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• 1997

The purpose of this study was to evaluate the bioflavonoids naringin on dental caries and periondontal disease in the albinorat. Twenty-five-day-old-male rats were fed the experimental diets for 42 days in this work at the end of the 42-day experimental period. The tooth surfaces were examined under a dissecting microscope. The sulcular caries lesions were recorded : the first molars were more affected than the second and third molars. Alveolar bone loss was measured on the buccal and lingual aspects of each molar: three site measurements (mesialpoint midpoint and distalpoint) were taken on the first molars. The results showed that the bioflavonoids, naringin had beneficial effects in the prevention of periodontal disease.

• Journal of Food Hygiene and Safety
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• v.14 no.1
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• pp.22-26
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• 1999

The purpose of this experiment was to examine the antimicrobial effect of the natural flavonoid hesperidin on dental caries and alveolar bone resorption in the albinorats. Twenty five day old male rats were fed with the experimental diets for 42 days. At the end of the 42 day experimental period, the molar tooth occlusal surface was examined by a dissecting microscope. The sulcular caries lesions were recorded: the first molar caries incidence was higher than that of the second molar and the third molar. Alvelolar bone resorption was measured on the buccal and lingual aspects of each molars. Three measurements were taken on the first molar (mesialpoint, midpoint, distalpoint). The results of this experiments, showed that hesperidin is effective in reducing dental caries and alveolar bone resorption.

• Journal of the korean academy of Pediatric Dentistry
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• v.23 no.4
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• pp.925-930
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• 1996

The purpose of this study was to know whether the information of caries activity and caries experience of the children can be used to predict the behavior of the children during the dental treatment. The subjects of the study were one hundred and eighty-one preschool children, three to six years old. Salivary reductase activity was tested by the Resazurin Disc Test. Caries experience was examined. The children's behavior was observed using the rating scale of Frankl. Salivary reductase activity of the negative behavior group was slightly higher than that of the positive behavior goup, but the difference was not significant. dt index and ds index of the negative behavior group were significantly higher than those of the positive behavior group. There were no significant differences in ft index and fs index between the two behavior groups. The results suggest that the negative behavior of a child can be predicted when the child has many untreated dental caries.

• Journal of Korean society of Dental Hygiene
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• v.8 no.2
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• pp.93-106
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• 2008

This study is to enforce to ready basic data of effective school dental health education for dental caries prevention， relation knowledge of class, feeding practice and snack intake preference actual conditions, food and caries executed investigation by own recording way using questionnaire consisted of dental health education awareness to some business world man high school locating in Kyonggi Province. Analyzes result that total 487 people respond in SPSS WIN 13.0 programs and got following sequence The obtain result were as follows 1. Results about habit of breakfast was the most by 36.1% a student who have breakfast every day, and a student who hardly eat dominated 32.9%. Second-year student hardly had breakfast (p<.01). 2. A student who answer that snack kind that often eat was cookies and snack kind was the most by 37.2%, and a student who answer that symbol drink was a carbonated drink was the most by 50.9%. 3. Relation knowledge degree appeared grand mean among 18 points perfect score by 12.36 with food and caries. Third-year student knowledge degree was the highest, and second-year student was the lowest knowledge degree by class (p<.01). 4. Existence and nonexistence of experience of dental health education appeared a student who experience that take dental health education does not exist by 57.1%. There was experience that take dental health education as class is low by class, and as class is high, experience did not exists (p<.05). 5. Time that take dental health education for the first time was the most by 56.7% a student who respond 'Babyhood', grade in school is low by class 'Babyhood', and is high by class responded 'Middle school'(p<.05). 6. Awareness of dental health education necessity 'may educate dental health and does not' a student 56.3%, half was looked attitude which students who exceed are insincere about dental health education necessity. 7. When educate dental health, contents was the most by 44.6% 'brushing and mouth article directions' to be educated importantly, and was expose by caries 31.2%, gum disease 10.1%, scaling 9.0%, prosthetic dentistry and implant 5.1% period of ten days, third-year student 50.8% said that 'brushing and mouth article directions' is important (p<.05). Dental health education is practiced during life, and is a teaching that should be remembered. Need to develop epoch-making and interesting education program that is correct in subject to do as quickly as possible, and should be achieved major road of dental hygienist. Dental hygienist will have to settle as quickly as possible as expert of prevention that is natural business and education and help in dental health education development under effort between country and dental association effective.

• Journal of the korean academy of Pediatric Dentistry
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• v.27 no.2
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• pp.202-207
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• 2000

The purpose of study was to compare the caries experience between the mentally retarded(MR) and the normal(N) children and adolescents and to survey the dental visit frequency. preventive dental care, and tooth-brushing behavior of the mentally retarded. Two hundred and fifty MR and two hundred and ten N subjects were selected for the study. 1. The number of teeth which had experienced caries was 3.28 in MR and 4.66 in N. The number of decayed teeth was 2.24 in MR and 1.50 in N. The number of filled teeth was 0.71 in MR and 3.06 in N Filled teeth rate was 19.78% in MR and 58.89% in N The differences between MR and N were all significant(P<0.01). 2. Dental visit frequency of MR was 1.15 per year, and the 51.2% of MR did not visit the dental clinic for the last one year. 38.0% of MR had received the preventive dental care. 3. Toothbrushing frequency per day was 2.16 and the toothbrushing time for 78.3% of MR was less than two minutes. 51.2% of MR brushed their teeth by themselves, 13.3% did with the help of the carers, and 35.5% totally depended on the carers. In conclusion, MR experienced less dental caries than N, had more untreated caries than N, and had need for regular preventive dental care.

• Biomedical Science Letters
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• v.13 no.4
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• pp.341-347
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• 2007

Streptococcus mutans, one of a major causal agents of dental caries, is component of the dental plaque and produces various organic acids such as lactic acid as the end-product of glycolysis. In this study, we isolated S. mutans from Korean children with caries and also investigated the expression of protein under acid stress. S. mutans was identified at the species level using a 16S ribosomal DNA sequencing comparison method. The primer specificity was tested on eleven S. mutans strains isolated from Korean children with caries. The data showed that eleven strains are S. mutans. At treatment of concentration of 20 mM lactic acid in the mid-log phage, K-7 exhibited the highest maximum culture OD compared with those of other groups. As a consequence, we examined the expression of protein under 20 mM lactic acid stress using S. mutans K-7. The results of 2D gel electrophoresis by image analysis showed that thirteen proteins are up-regulated under the stress. Further study is being focused on amino acid analysis by mass spectrometry in order to analyze those spots.

• International Journal of Oral Biology
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• v.43 no.1
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• pp.37-42
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• 2018

It is noted that Streptococcus mutans (S. mutans) triggers dental caries establishment by two major factors: the synthesis of organic acids, which demineralize dental enamel, and the synthesis of glucans, which mediate the attachment of bacteria to the tooth surface. Therefore, it is noted that the development of a more effective, substantial and safe preventive agent that works against dental caries and periodontal disease is required at this time. For this reason, the present study was designed to investigate the effect of croton seed ethanol extracts on the growth, acid production, adhesion, and insoluble glucan synthesis of S. mutans. In this case, the ethanol extract of croton seed showed concentration dependent inhibitory activity against the growth, acid production and adhesion of S. mutans. Especially, it is important to note that it has produced significant inhibition at the concentration of 0.1 and 0.2 mg/ml as compared to the control group. Moreover, these results suggest that the application of croton seed extract may be considered to be a useful method for the prevention of dental caries.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.8
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• pp.1424-1429
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• 2016

Segmentation is one of the first steps in most diagnosis systems for characterization of dental caries in an early stage. The purpose of automatic dental cavity detection system is helping dentist to make more precise diagnosis. We proposed the semi-automatic method for the segmentation of dental caries on digital x-ray images. Based on a manually and roughly selected ROI (Region of Interest), it calculated the contour for the dental cavity. A snake algorithm which is one of active contour models repetitively refined the initial contour and self-examination and correction on the segmentation result. Seven phantom tooth from incisor to molar were made for the evaluation of the developed algorithm. They contained a different form of cavities and each phantom tooth has two dental cavities. From 14 dental cavities, twelve cavities were accurately detected including small cavities. And two cavities were segmented partly. It demonstrates the practical feasibility of the dental lesion detection using Computer-aided Detection (CADe).

• Restorative Dentistry and Endodontics
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• v.19 no.2
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• pp.372-383
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• 1994

Saliva plays an important role in modulating the oral microbial ecology. And it is suggested to influence the initiation and progression of the dental caries. To evaluate the correlations between the salivary antimicrobial agents and the caries susceptibility, the 51 subjects were divided into 3 groups according to caries experience ; caries resistant group, medium caries susceptible group, and high caries susceptible group. Stimulated whole saliva was collected, and the salivary levels were measured for lysozyme, lactoferrin, and secretory-IgA to Streptococcus mutans. The lysozyme level was estimated using Micrococcus diffusion plate, lactoferrin level was determined with a non-competitive avidin-biotin enzyme immunoassay, and the titer of secretory IgA to Streptococcus mutans was assayed with ELISA. The results were as follows: 1. Lysozyme levels of each group showed no significant difference statistically (p>0.05). 2. The caries resistant group and the medium caries susceptible group had significantly higher levels of lactoferrin than the high caries susceptible group (p<0.05). But no clear difference was observed between the caries resistant group and the medium caries susceptible group(p>0.05). 3. The caries resistant group and the medium caries susceptible group showed relatively higher levels of the secretory IgA to Streptococcus mutans than the pigh caries susceptible group, but no significant difference was observed statistically (p>0.05).

• Restorative Dentistry and Endodontics
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• v.9 no.1
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• pp.37-49
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• 1983

This study was undertaken to observe the relationship between salivary IgA, IgG, agglutinin titer & dental caries. The subjects divided into two groups, an active caries group (AC group) and caries-free and treated caries group (CFTC group). The AC group consisted of 36 subjects who had one or more carious lesions and the CFTC group of 12 subjects who had no evidence of caries or had filled teeth without present carious teeth for the last six months. The IgA, IgG and IgM levels in their saliva were measured by single radial immunodiffusion method using a disposable low-level immunodiffusion plate. The salivary agglutinin titers to Streptococcus mutans were measured by microtitration system. The results were as follow; 1. The mean value of IgA concentration in saliva of AC group was slightly higher than that of CFTC group, but its difference was slight. 2. The mean value of IgG concentration in saliva of AC group was slightly lower than that of CFTC group. The IgM concentration in saliva of both groups was neither below 1.1 mg/dl nor detected on LC partigen immunodiffusion plate. 3. There was no difference in the agglutinin titer to S. mutans antigen by serotypes, but low level agglutinin to type d was measured in both groups. 4. AC group showed low correlation between IgA, IgG & DMFT, but CFTC group revealed negative correlation. 5. The relationship between salivary IgA & agglutinin titers to S. mutans was low correlation in AC group, but CFTC group showed significant positive correlation. (P<0.05) 6. There were no specific correlations among the concentrations of salivary immunoglobulins, agglutinin titers to S. mutans, and the DMF teeth. They had no close concern to induce the dental caries.