• 한국포장학회지
• /
• 제26권2호
• /
• pp.99-103
• /
• 2020

The volume of parcel delivery is steadily increasing with the rapid growth of the global online e-commerce market. However, a large amount of packaging materials used for these parcel delivery is finally causing environmental problems as waste. In this study, we have taken a pilot test on the returnable parcel delivery packaging & service, which is one of various ways to reduce the generation of the distribution packaging waste raised by e-commerce-based parcel delivery. For the purpose of this project, we made 300 boxes of returnable & foldable delivery packaging(415 mm × 280 mm × 160 mm) and have cooperated with e-commerce company(CJ ENM) & logistics company(LogisAll). Consequently, about 50% of the delivered packages was returned because of the lack of consumer's understanding on the returnable packaging system. We finally have suggested the policy strategy to get over problems derived from the experiment, like the retrieval rate and cost of the returnable packaging, economic efficiency and so on.

• International journal of advanced smart convergence
• /
• 제12권1호
• /
• pp.220-229
• /
• 2023

The development of logistics technology due to the 4th Industrial Revolution and logistics 4.0 has changed the logistics environment from offline to online, and the growth of the online market has accelerated due to the recent increase in non-face-to-face delivery due to COVID-19. Such growth in the online market has expanded the logistics market for delivery, and contributes to creating an advanced logistics ecosystem as last mile services and logistics technologies begin to grow together. As traffic and environmental problems arise as a result, interest in transportation means of cargo increases, and changes to cargo electric vehicles and delivery cycles are being considered. However, since mass transportation of transportation focused on terminal delivery such as cargo electric vehicles and delivery cycles is limited in handling large quantities in urban areas, methods for efficiently transporting cargo while considering the environment are being devised. In order to solve such environmental problems and increase the efficiency of logistics delivery in urban areas, technologies using underground spaces based on existing urban railroads are being developed. In this study, a study was conducted on the establishment of evaluation criteria for selecting a test bed, which is a space for applying the system.

• 로봇학회논문지
• /
• 제18권1호
• /
• pp.10-17
• /
• 2023

Recently, robots have been actively utilized for logistics and delivery services in various places such as restaurants, hotels, and hospitals. In addition, it provides a safer environment, convenience, and cost efficiency to the customers. However, when it comes to autonomous delivery in a multi-floor environment, the task is still challenging. Especially for wheeled mobile robots, it is necessary to deal with elevators to perform the last-mile delivery services. Therefore, we present a multi-floor route planning algorithm that enables a wheeled mobile robot to traverse an elevator for the delivery service. In addition, an elevator boarding mission algorithm was developed to perceive the drivable region within the elevator and generate a feasible path that is collision-free. The algorithm was tested with real-world experiments and was demonstrated to perform autonomous postal delivery service in a multi-floor building. We concluded that our study could contribute to building a stable autonomous driving robot system for a multi-floor environment.

• Journal of Microbiology and Biotechnology
• /
• 제21권8호
• /
• pp.802-807
• /
• 2011

Cationic liposomes have been actively used as gene delivery vehicle because of their minimal toxicity, but their relatively low efficiency of gene delivery is the major disadvantage of these vectors. Recently, cysteine residue incorporation to HIV-1 Tat peptide increased liposomemediated transfection compared with unmodified Tat peptide. Therefore, we designed a novel modified Tat peptide having a homodimeric (Tat-CTHD, Tat-NTHD) and closed structure (cyclic Tat) simply by using the disulfide bond between cysteines to develop a more efficient and safe nonviral gene delivery system. The mixing of Tat-CTHD and Tat-NTHD with DNA before mixing with lipofectamine increased the transfection efficiency compared with unmodified Tat peptide and lipofectamine only in MCF-7 breast cancer cells and rat vascular smooth muscle cells. However, cyclic Tat did not show any improvement in the transfection efficiency. In the gel retardation assay, Tat-CTHD and Tat-NTHD showed more strong binding with DNA than unmodified Tat and cyclic Tat peptide. This enhancement was only shown when Tat-CTHD and Tat-NTHD were mixed with DNA before mixing with lipofectamine. The effects of Tat- CTHD and Tat-NTHD were also valid in the experiment using DOTAP and DMRIE instead of lipofectamine. We could not find any significant cytotoxicity in the working concentration and more usage of these peptides. In conclusion, we have designed a novel transfection-enhancing peptide by easy homodimerization of Tat peptide, and the simple mix of these novel peptides with DNA increased the gene transfer of cationic lipids more efficiently with no additional cytotoxicity.

• Journal of Pharmaceutical Investigation
• /
• 제40권spc호
• /
• pp.75-82
• /
• 2010

Specific diseases like cancer and acquired immune deficiency syndrome (AIDS) occur at various organs including lymphatics and spread through lymphatic system. Thus, if therapeutic agents for such diseases are more distributed or targeted to lymphatic system, we can obtain several advantages like reduction of systemic side effect and increase of efficacy. For these reasons, much interest has been focused on the nature of lymphatics and a lot of studies for lymphatic delivery of drugs have been carried out. Because lymphatics consist of single layer endothelium and have high permeability compared with blood capillaries, especially, the studies using nano-sized carriers have been performed. Polymeric nano-particle, liposome, and lipid-based vehicle have been adopted for lymphatic delivery as carriers. According to the administration route and the kind of carrier, the extent of lymphatic delivery efficiency of nano-sized carriers has been changed and influenced by several factors such as size, charge, hydrophobicity and surface feature of carrier. In this review, we summarized the key factors which affect lymphatic uptake and the major features of carriers for achieving the lymphatic delivery. Lymphatic delivery of drug using nano-sized carriers has many fold improved ability of lymphatic delivery compared with that of conventional dosage forms, but it has not shown whole lymph selectivity yet. Even though nano-sized carriers still have the potential and worth to study as lymphatic drug delivery technology as before, full understanding of delivery mechanism and influencing factors, and setting of pharmacokinetic model are required for more ideal lymphatic delivery of drug.

• 한국경영과학회:학술대회논문집
• /
• 한국경영과학회 2001년도 추계학술대회 논문집
• /
• pp.7-10
• /
• 2001

The development of information communication technology leads the growth of logistic industry including delivery service as well as electronic commerce. The researchers predict that it will be still improving for the next several years. The logistic information system of railroad courier has been growing for a long time with small-package delivery transportation which is similar to the land-road delivery system. Despite of the long-time growth, it is recently in pain of the great loss since the 1990's, due to the failure to satisfy the customer's need for door-to-door delivery service. But the logistic information system of railroad still has the great potential. There are so many benefits such as timeliness, Punctuality, speed, multi-node storage base, transportation efficiency, energy frugality, environmental sociability, and so on. If the railroad logistic system plays a role of a portion of the nation-wide logistic with other logistic system, the synergy through the balancing logistic will also get much of international competitive advantages. So the objective of this research is to design the model and prototype of the web-based logistic system from which railroad service provider(Korean National Railroad), delivery service providers, and the customers can share the best effective delivery information.

• Journal of Communications and Networks
• /
• 제15권2호
• /
• pp.198-206
• /
• 2013

Recent advances in forward error correction (FEC) coding techniques were focused on addressing the challenges of multicast and broadcast delivery. However, FEC approaches can also be used for unicast content delivery in order to solve transmission control protocol issues found in wireless networks. In this paper, we exploit the error resilient properties of Raptor codes by proposing Raptor-based content delivery protocol (RCDP) - a novel solution for reliable and bidirectional unicast communication in lossy links that can improve content delivery in situations where the wireless network is the bottleneck. RCDP has been designed, validated, optimized, and its performance has been analyzed in terms of throughput and resource efficiency. Experimental results show that RCDP is a highly efficient solution for environments characterized by high delays and packet losses making it very suitable for intelligent transport system oriented applications since it achieves significant performance improvements when compared to traditional transport layer protocols.

• 보건행정학회지
• /
• 제29권3호
• /
• pp.248-261
• /
• 2019

Establishing a healthcare delivery system is key to building a cost-effective healthcare system that can prevent the waste of healthcare resources and increase efficiency. Recently, the rapid increase in the national medical expenditures due to the aging of the population and the increase in chronic diseases has raised the question about the sustainability of the healthcare system including the health insurance system. This is why we need to reform the medical delivery system, including the function setting of medical institutions. Accordingly, gradual and practical efforts based on the recognition of reality are needed for solving the problems and improving the medical delivery system. The first effort is to secure policy measures to establish functions and roles of medical institutions which are the basis of the healthcare delivery system, and a systematic medical use system for appropriate medical use. This approach can be achieved through a reasonable health insurance schemes. Without reasonable reform efforts, it will be difficult for Korea's health care system to develop into a system that can provide cost-effective and high-quality medical services that the people want.

• Macromolecular Research
• /
• 제16권8호
• /
• pp.682-685
• /
• 2008

The aim of this work was to develop and evaluate solid lipid nanoparticles (SLN) containing all-trans-retinoic acid (ATRA) for topical delivery. SLN composed of coconut oil and curdlan improved the suspension instability of ATRA in aqueous solution. The photodegradation of ATRA by light was reduced by incorporation in SLN. The loading efficiency of ATRA in SLN was higher than 95% (w/w). The amounts of ATRA released from SLN at $4^{\circ}C$ and at $37^{\circ}C$ were less than 15% and more than 60% (w/w) for 96 h, respectively. The ATRA-loaded SLN can be used as a potential carrier for topical delivery.

• Management Science and Financial Engineering
• /
• 제13권1호
• /
• pp.55-72
• /
• 2007

We consider the product differentiation model of online channel competition and examine the strategies of hybrid firms in terms of efficiency. After measuring the social cost of online business strategies, we show that (i) online channel of hybrid firm under blockaded entry may increase the social cost if the firms' delivery cost is sufficiently smaller than the consumer's transportation cost, and (ii) online competition under free entry may increase the social cost if the firms' delivery cost is sufficiently larger than the consumer's transportation cost. Finally, we discuss the strategic incentive of hybrid firms to reduce delivery cost and investigate the effect of the Internet maturity on the social cost.