• The Journal of Internal Korean Medicine
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• v.40 no.3
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• pp.369-389
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• 2019

Objectives: This study aimed to analyze the correlation between Ryodoraku diagnosis and three pattern identification questionnaires, namely, Spleen Qi Deficiency, Stomach Qi Deficiency, and Food Retention in functional dyspepsia (FD) patients. Methods: Forty FD patients who met the Rome IV diagnostic criteria for FD participated in this study. The Ryodoraku test was conducted, and three pattern identification questionnaires were filled up by all patients. The average Ryodoraku score was called total average (TA), and the scores on the Ryodoraku points were measured. The degree of Spleen Qi Deficiency, Stomach Qi Deficiency, and Food Retention was assessed by Spleen Qi Deficiency questionnaire (SQDQ), Scale for Stomach Qi Deficiency pattern (SSQD), and Food Retention Questionnaire (FRQ). Results: The TA scores in the SQDQ patient group were lower than those in the SQDQ control group (p=0.091). The TA scores in the SSQD patient group were higher than those in the SSQD control group (p=0.651). The TA scores in the FRQ patient group were lower than those in the FRQ control group (p=0.851). The scores on the LH5, RH5, and RH6 points were significantly lower in the SQDQ patient group than in the SQDQ control group. However, no significant difference was found in the Ryodoraku scores among the other groups. Conclusions: The results suggest that the low TA and low Ryodoraku scores on the LH5, RH5, and RH6 points could be a quantitative indicator to diagnose Spleen Qi Deficiency in FD patients in a simpler manner. Larger studies on the Ryodoraku test in FD patients, the health control group, and other pattern identification groups are required.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.3
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• pp.77-86
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• 2019

Objectives : By analyzing symptoms of tinnitus, we tried to find out the relationship between deficiency and excess(虛實) and visceral pattern identification(臟腑辨證). By testing Tinnitus Handicap Inventory(THI), we evaluated the quality of life of people suffering from various aspects of tinnitus, as well as comparing treatment efficiency. Methods : 52 patients were recruited in this study who was ill with tinnitus. They wrote out the questionnaire about tinnitus and the THI. Results : The vast majority of high-grade tiny noise patients are deficiency type(虛症). The vast majority of low-grade roar patients are excess type(實症). Tinnitus persistence and feeling of ear occlusion were prominent in low-grade roar patients. low-grade roar patients suggest that overall quality of life is lower than high-grade tiny noise patients. In terms of treatment efficiency, spleen-stomach weakness(脾胃虛弱)-type, stomach heat(胃熱)-type and phlegm-fire(痰火)-type was higher than kidney essence depletion(腎精虧損)-type and liver qi depression(肝氣鬱結)-type regardless of the aspect of tinnitus. Conclusions : The present study suggests that tinnitus pattern may be helpful in differentiating patients with tinnitus, and the effectiveness of treatment can be predicted through differentiation.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.1
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• pp.76-88
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• 2009

Back ground and Objective : There is a need for objectification and scientific verification of Pattern identification in Oriental medicine. The purpose of this study was to investigate the skin characteristics of Qi deficiency and Blood deficiency animal models. Material and Methods : Sprague-Dawley rats were divided into three groups: normal group, Qi deficiency group and Blood deficiency group. The Qi deficiency animal model was induced through restriction of food (75g/kg/day) for 20 days. Blood deficiency animal model was induced by bleeding from tail vein(0.3 ml/time) 8 times. The normal animal model was kept without any intervention. The general condition was observed by measuring body weight, body temperature, blood pressure, pulse rate, and hematological and biochemical parameters. The skin characteristics were observed by measuring the erythema index(EI), melanin index(Ml), transepidermal water loss(TEWL) and dermal microcirculation. Results : 1. In the Qi deficiency group, body weight was lower than the other groups. In the Qi deficiency group, blood pressure was lower than in the Normal group. There was no difference in body temperature and pulse rate between the three groups. 2. In the Qi deficiency group, blood sugar was lower than in the Blood deficiency group. There was no difference in triacylglycerol between the three groups. In the Qi deficiency group, the WBC count was lower than in the Blood deficiency group. RBC count was highest in the Qi deficiency group, Normal group and Blood deficiency group respectively. In the Qi deficiency group, Hb and Hct were higher than the other groups. 3. EI and MI were decreased in the Qi deficiency group, and EI showed a significant decrease. 4. EI and MI were increased in the Blood deficiency group, and MI showed a significant increase. 5. TEWL was significantly increased in the Qi deficiency group, while it was decreased in the Blood deficiency group, TEWL was highest in the Qi deficiency group, Normal group and Blood deficiency group respectively and all three groups showed significant difference. 6. In the Qi deficiency group, dermal microcirculation was lower than the other groups. Conclusion : The above results show that the erythema index decreases in the Qi deficiency model, and the melanin index increases in the Blood deficiency model. The Qi deficiency animal model shows an increase in transepidermal water loss, while the Blood deficiency animal model shows a decrease. Further studies should develop new models of Pattern Identification that are more specific.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.3
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• pp.251-262
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• 2014

This article is for understanding dementia with the perspective of Korean Medicine through research on syndrome differentiations of dementia clinically applied and relations between modern diseases and Korean Medicine pattern types of dementia. clinical papers were searched in China Academic Journals(CAJ) of China National Knowledge Infrastructure(CNKI) from 2012 to 2013. Conclusions are as follows. First, dementia was expressed in many ways such as imbecility, stupidity, fatuity, idiocy, vacuity, etc and was related with amnesia, forgetfulness, speech not in the right order, depressive psychosis(quiet insanity), manic psychosis, depression syndrome. Second, prescriptions such as QiFuYin and ZuoGuiWan from JingYueQuanShu, XiXinTang and ZhiMiTang from BianZhengLu, TongQiaoHuoXueTang, XueFuZhuYuTang and BuYangHaiWuTang from YiLinGaiCuo, HaiShaoDan from YiFangJiJie, HuangLianJieDuTang from WaiTaiMiYao were suggested for dementia. Third, syndrome differentiation pattern types of dementia are kidney deficiency and marrow decrease, qi-blood depletion, liver-kidney depletion, spleen-kidney depletion, heart-spleen deficiency as deficiency patterns and effulgent heart-liver fire, ascendant hyperactivity of liver yang, qi stagnation and blood stasis, phlegm turbidity obstructing orifice, phlegm-blood stasis obstructing orifice, intense heat toxin as excess patterns and qi deficiency with blood stasis, yin deficiency with yang hyperactivity as deficiency-excess complex patterns. Major pattern types are kidney deficiency and marrow decrease, phlegm-blood stasis obstructing orifice, qi stagnation and blood stasis, liver-kidney depletion, phlegm turbidity obstructing orifice.

• The Journal of Internal Korean Medicine
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• v.40 no.4
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• pp.582-596
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• 2019

Objective: The aims of this study were to analyze the deficiency-excess pattern identification (虛實辨證) and compare it to the sputum cytokines of asthma patients. Method: 50 asthma patients who met the inclusion and exclusion criteria were included in this study. They were divided into two groups: deficiency and excess syndrome groups. Sputum examinations were performed including $TNF-{\alpha}$, Interleukin (IL)-4, IL-5, IL-10, and IL-13. The Quality of Life Questionnaire for Adult Korean Asthmatics (QLQAKA), the Visual Analog Scale(VAS), and heart rate variability (HRV) were also measured. We also conducted laboratory tests, including the hematological indexes. Results: Based on the pattern identification, 50 asthma patients can be divided into two categories of groups: the deficiency syndrome group (N=24) and the excess syndrome group (N=26). In the analysis of sputum cytokines, although the $TNF-{\alpha}$, IL-4 and IL-13 were at a higher level in the deficient pattern group than in the excess pattern group, it was insignificantly different. There was a negative correlation in the analysis of QLQAKA and VAS. In the analysis of HRV, although the mean value of VLF, LF, and HF in the deficiency syndrome group was higher than in the excess syndrome group, it was insignificantly different. There was no significant difference in the hematological tests between the deficiency and the excess syndrome group. The mean value of the IgE in the blood tests was five times greater than the reference value. Conclusion: The cytokines of sputum including $TNF-{\alpha}$, IL-4, IL-5, IL-10, and IL-13 were indifferent statistically. Reinforcing the healthy and eliminating the pathogenic factors should be considered.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.2
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• pp.453-458
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• 2008

This study aimed to develop an evaluation reliability of Korean pattern identification for wind stroke. We studied 643 patients with stroke and made a list of registry for each of them. The present study analyzed 553 cases, in which the resident’s pattern identification agreed with the specialist’s one, and the cases included five differentiation pattern: the fire-heat pattern (114), the dampness-phlegm pattern (157), the static blood pattern (11), the Yin deficiency pattern (81), and the Qi deficiency pattern (190). This study showed that none of the Cronbach's alpha reached 0.700, which is the general reliable level. The average Cronbach's alpha of each symptoms was 0.353 for the dampness-phlegm pattern, 0.571 for the fire-heat pattern, 0.443 for the Qi deficiency pattern, 0.451 for the Yin deficiency pattern, and 0.302 for the static blood pattern. This suggests the possibility that each pattern identification could be coincided with other symptoms, and it also shows the limits of pattern identification of this study that narrows the symptoms of paralysis patients into only a single pattern. Continuous compliments and researches should be done referring to this matter. However, the internal consistency analysis of all the pattern identification showed that every Cronbach's alpha were within the range of 0.670 to 0.703, and the Cronbach's alpha of the whole symptoms was evaluated as 0.692, which makes the reliability of the pattern identification as itself almost satisfactory to the general reliable level, and therefore, significant. In the future, continuous clinical research to develope this pattern identification for wind stroke actually applicable to stroke patients needs to be made through accumulating more cases, improving the objectivity.

• Korean Journal of Oriental Medicine
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• v.16 no.3
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• pp.33-44
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• 2010

Pulse diagnosis is considered one of the most important diagnostic methods in traditional Korean medicine. Nonetheless, there have been troubles of using pulse diagnosis practically, for the lack of its differential standards and standardized terminology. Rapid pulse belongs to the several traditional pulse types. Rapid pulse was first mentioned in the chinese medical book Haungdineijin that matched it to the fever as well as yang in the human body. Meanwhile, chinese doctors in Ming Ching dynasty of China suggested that rapid pulse meant more of the yin, cold-related reaction than yang and fever. In this study, we organized the past arguments of the rapid pulse and went back tracking what biological activities could be possibly linked to the rapid pulse. Thus, we figured out that the inflammatory mechanism has a close connection with the rapid pulse. The definition of the rapid pulse in Haungdineijin was indicating the acute inflammatory response, while in Ming Ching dynasty, it indicated the chronic inflammation. This is the deficiency-excess pattern of the rapid pulse. Furthermore, we discussed the nonexpression pattern of the rapid pulse which could be happened in case of the heat stroke, etc.

• The Journal of Korean Obstetrics and Gynecology
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• v.29 no.2
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• pp.29-46
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• 2016

Objectives : The aim of this study is development of questionnaire for pattern identification of infertility and analysis of infertility treatment trend in korean traditional medicine. Methods : Data was collected by survey papers from 19 professors of the society of korean obstetrics and gynecology. We surveyed on pattern identifications, symptoms and prescriptions of infertility treatment, diagnosis of ovulation and pregnancy, and duration of infertility treatment. Results : By analysis of survey papers, We choose Kidney yang deficiency, Kidney yin deficiency, Blood deficiency, Liver depression, Dampness-phlegm, Dampness-heat, Static blood pattern for infertility treatment. And 41 items of questionnaire were chosen. Conclusions : We developed the questionnaire for pattern identification of infertility. And further research is necessary for improvement reliabilities and validities of the questionnaire of infertility.

• The Journal of Korean Medical History
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• v.27 no.2
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• pp.135-143
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• 2014

Human body fluid and humor include not only sweat, joint fluid but also every fluids, for example, blood, essence, kidney essence and marrow. Historically, in the oriental medicine, there are a lot of efforts in order to preserve fluid and humor. In "Treatise on Cold Damage and Miscellaneous Disease (傷寒雜病論)", when treating cold damage, preservation of fluid and humor is put first. I tried to find out the relation about fluid and humor and pain treatment in "Treatise on Cold Damage and Miscellaneous Disease". So, I investigated sentences related to pains in "Treatise on Cold Damage and Miscellaneous Disease" "greater yang disease part" and commentaries of several chinese medical doctors. And I divide pain treatments into four categories. (fluid and humor sufficiency-exterior pattern, fluid and humor sufficiency-interior pattern, fluid and humor deficiency-exterior pattern, fluid and humor deficiency-interior pattern) At first, when treating pains of cold damage, there are many considerations about deficiency and sufficiency of fluid and humor through pulse condition and symptoms. Second, in pain-cases of fluid and humor sufficiency, purge methods is chosen. And in pain-cases of fluid and humor deficiency, tonifying methods is chosen. Finally, one of the main objects of "Treatise on Cold Damage and Miscellaneous Disease" is preservation and supply of fluid and humor.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.18 no.3
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• pp.149-174
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• 2014

Objectives to study definition and treatment of dizziness in the books of Cold damage which are classified as symptoms of all time. Methods 1. Quote provisions related to dizziness in "Sanghanlon(傷寒論)" 2. Among the books of Cold damage which are classified as symptoms, select 19 literatures on dizziness with table of contents and collect data and categorize in two perspectives on theories and disease pattern. 3. Compare and draw a chart all data collected in above methods. Results & Conclusions 1. In the books on Cold damage, dizziness is expressed in 2 ways such as head dizziness(頭眩) and fainting(鬱冒). fainting is much more several symptoms than head dizziness and it is the difference that it has mental confusion. 2. The cause of head dizziness after promoting sweating, vomiting and purgation is that source qi(元氣) of upper energizer(上焦) is deficiency, and cause of head dizziness before using method of treatment is wind(風), heat(熱), phlegm(痰), blood deficiency(血虛) and etc. 3. Main cause of fainting is that deficiency is getting severe so that cold invades, and symptoms are blood deficiency, after giving birth and excess pattern of fire and heat. 4. Remedies for head dizziness are using Yeonggyechulgam-tang(苓桂朮甘湯), jinmu-tang(眞武湯), sosiho-tang(小柴胡湯), sagunja-tang(四君子湯), samul-tang(四物湯) and etc. 5. Insamsambaek-tang (人蔘三白湯) and Sayeok-tang(四逆湯) are used for deficiency pattern of fainting, and Dojeok-san(導赤散), Daeseunggi-tang(大承氣湯), and Hwangryeonhaedok-tang(黃連解毒湯) are used for excess pattern(實證).