References
- Sugita M, Kuribayashi K, Nakagomi T, Miyata S, Matsuyama T, Kitada O. Allergic bronchial asthma: airway inflammation and hyperresponsiveness. Intern Med 2003;42(8):636-43. https://doi.org/10.2169/internalmedicine.42.636
- Masoli M, Fabian D, Holt S, Beasley R. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004;59(5):469-78. https://doi.org/10.1111/j.1398-9995.2004.00526.x
- WHO. Asthma fact sheet Updated April 2017.
- Hwang WS, Lee JS, Joo CY, Jung HJ, Lee HG, Jung SK. The Clinical Study on 1 Case of Hyperthyroid patient Treated with Yukmijihwangtang. The J of Oriental Chronic Diseases 2002;8(1):53-63.
- Gan HJ. Studies on Relationship Between Cold-heat Asthma at Stage of Attack of Bronchial Asthma and ET-1 and ANF. J of Shaanxi College of Traditional Chinese Medicine 2003;26(5):64-6. https://doi.org/10.3969/j.issn.1002-168X.2003.05.043
- LI ZY, LIU WW. Clinical Study on Immunity, Adrenocortical Function and Platelet Activation in Cold Heat Type of Attack Stage of Child Asthma. J of Fujian College of Traditional Chinese Medicine 2001-01.
- Cao YX, Dong JC, Du YJ. Biomarkers and inflammatory characteristics for microcosmic syndrome differentiation of cold-phlegm syndrome and heat-phlegm syndrome in patients with bronchial asthma. Zhongguo Zhong Xi Yi Jie He Za Zhi 2010;30(8):828-32.
- Bhang YH, Kim JH, Do HY, Kim MA, Kim KI, Jung HJ. Deficiency-excess and Cold-heat Pattern Identification and Analysis of the Characteristics of Asthma Patients. J Int Korean Med 2017;38(6):955-70. https://doi.org/10.22246/jikm.2017.38.6.955
- Park JW, Cho YS, Lee SY, Nahm DH, Kim YK, Kim DK, et al. Multi - center study for the utilization of quality of life questionnaire for adult Korean asthmatics (QLQAKA). J of asthma, allergy and clinical immunology 2000;20(23):467-79.
- Korean Society for Tuberculosis and Respiratory Diseases. Asthma medical guidelines 2014 revise. 2014:3.
- Ministry of Health and Welfare Centers for Disease Control and Prevention. 2015 National Health Statistics National Nutrition Survey 6th (2015). 2016:316-7.
- Kim BK. Korean Diagnostics. Seoul: Sungbosa; 1986, p. 25, 42.
- The National University of Dept. of Internal Medicine Pulmonary System. Internal Medicine Pulmonary System. Seoul: Nado; 2011, p. 273-81.
- Chlumsky J, Striz I, Terl M, Vondracek J. Strategy aimed at reduction of sputum eosinophils decreases exacerbation rate in patients with asthma. J Int Med Res 2006;34(2):129-39. https://doi.org/10.1177/147323000603400202
- Gibson PG, Fujimura M, Niimi A. Eosinophilic bronchitis: clinical manifestations and implications for treatment. Thorax 2002;57(2):178-82. https://doi.org/10.1136/thorax.57.2.178
- Jatakanon A, Uasuf C, Maziak W, Lim S, Chung KF, Barnes PJ. Neutrophilic inflammation in severe persistent asthma. Am J Respir Crit Care Med 1999;160(5 Pt 1):1532-9. https://doi.org/10.1164/ajrccm.160.5.9806170
- Haldar P, Pavord ID. Noneosinophilic asthma: a distinct clinical and pathologic phenotype. J Allergy Clin Immunol 2007;119(5):1043-52. https://doi.org/10.1016/j.jaci.2007.02.042
- Sim MK, Choi IS, Kim WJ. Change of Inflammatory Markers in Induced Sputum in Suspected Asthmatics by Asthma Treatment. The Korean Academy of Asthma, Allergy, Clinical Immunology 2012;32(3):159-68.
-
Cazzola M, Polosa R. Anti-TNF-
$\alpha$ and Th1 cytokine-directed therapies for the treatment of asthma. Curr Opin Allergy Clin Immunol 2006;6(1):43-50. https://doi.org/10.1097/01.all.0000199798.10047.74 - Thomas PS, Heywood G. Effects of inhaled tumor necrosis factor alpha in subjects with mild asthma. Thorax 2002;57(9):774-8. https://doi.org/10.1136/thorax.57.9.774
-
Cho SH, Stanciu LA, Holgate ST, Johnston SL. Increased interleukin-4, interleukin-5 and interferon-
$\gamma$ in airway CD4+ and CD8+ T cells in atopic asthma. Am J Respir Crit Care Med 2005;171(3):224-30. https://doi.org/10.1164/rccm.200310-1416OC - Commins SP, Borish L, Steinke JW. Immunologic messenger molecules: cytokines, interferons, and chemokines. J Allergy Clin Immunol 2010;125 (2 Suppl 2):S53-72. https://doi.org/10.1016/j.jaci.2009.07.008
- Ownby DR, Johnson CC. Factors underlying the increasing incidence and prevalence of allergic diseases. In: Adkinson NF Jr, Busse WW, Bochner BS, Holgate ST, Simons FER, Lemanske RF Jr. Middleton's allergy: principles and practice. 7th ed. Philadelphia: Mosby Elsevier; 2009, p. 769-78.
- Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989;170(6):2081-95. https://doi.org/10.1084/jem.170.6.2081
- Borish L. IL-10: evolving concepts. J Allergy Clin Immunol 1998;101(3):293-7. https://doi.org/10.1016/S0091-6749(98)70238-6