• Molecules and Cells
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• v.40 no.2
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• pp.83-89
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• 2017

Error-free replication and repair of DNA are pivotal to organisms for faithful transmission of their genetic information. Cells orchestrate complex signaling networks that sense and resolve DNA damage. Post-translational protein modifications by ubiquitin and ubiquitin-like proteins, including SUMO and NEDD8, are critically involved in DNA damage response (DDR) and DNA damage tolerance (DDT). The expression of interferon-stimulated gene 15 (ISG15), the first identified ubiquitin-like protein, has recently been shown to be induced under various DNA damage conditions, such as exposure to UV, camptothecin, and doxorubicin. Here we overview the recent findings on the role of ISG15 and its conjugation to target proteins (e.g., p53,$ {\Delta}Np63{\alpha}$, and PCNA) in the control of cellular responses to genotoxic stress, such as the inhibition of cell growth and tumorigenesis.

• Proceedings of the IEEK Conference
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• 2004.08c
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• pp.460-462
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• 2004

The control of the data retention time is a main issue for realizing future high density dynamic random access memory. There are several leakage current mechanisms in which the stored data disappears. The mechanisms of data disappear is as follow, 1 )Junction leakage current between the junction, 2) Junction leakage current from the capacitor node contact, 3)Sub-threshold leakage current if the transfer transistor is affected by gate etch damage etc. In this paper we showed the plasma edge damage effect to find out data retention time effectiveness. First we measured the transistor characteristics of forward and reverse bias. And junction leakage characteristics are measured with/without plasma damage by HP4145. Finally, we showed the comparison TRET with etch damage, damage_cure_RTP and hydrogen_treatment. As a result, hydrogen_treatment is superior than any other method in a curing plasma etch damage side.

• Transactions of Materials Processing
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• v.4 no.2
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• pp.131-140
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• 1995

In this paper damage propagation of a material during forming is investigated with the concept of continuum damage mechanics. An isotropic damage model based on the theory of materials of type N is adopted to describe the damage process of a ductile material with large elasto-viscoplastic deformation. The stiffness degradation of the loaded material is chosen as a damage measure. The highly nonlinear equilibrium equations are reduced to the incremental weak form and approximated by the total Lagrangian finite element method. To simulate contact condition, extended interior penalty method with modified coulomb friction law is adopted. The displacement control method along with the modified Riks' continuation technique is used to solve the incremental iterative equations. As numerical examples, upsetting problem and backward extrusion problem are simulated and the results of damage propagation and $J_2$ stress contours with and without friction are presented.

• Structural Engineering and Mechanics
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• v.54 no.2
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• pp.221-237
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• 2015

An integrated method is proposed for structural nonlinear damage detection based on time series analysis and the higher statistical moments of structural responses in this study. It combines the time series analysis, the higher statistical moments of AR model residual errors and the fuzzy c-means (FCM) clustering techniques. A few comprehensive damage indexes are developed in the arithmetic and geometric mean of the higher statistical moments, and are classified by using the FCM clustering method to achieve nonlinear damage detection. A series of the measured response data, downloaded from the web site of the Los Alamos National Laboratory (LANL) USA, from a three-storey building structure considering the environmental variety as well as different nonlinear damage cases, are analyzed and used to assess the performance of the new nonlinear damage detection method. The effectiveness and robustness of the new proposed method are finally analyzed and concluded.

• Journal of Mechanical Science and Technology
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• v.19 no.10
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• pp.1891-1901
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• 2005

Recently the authors tried to find damage position only using measured frequency response functions. According to their work, it seems that the algorithm is very practical since it needs only measured frequency responses while other methods require exact analytic model. But when applying the method to a real structure, it requires lots of experiment. The authors, in this time, propose a method to reduce its experimental load by detecting damage within a substructure. This method searches damages not within an entire structure but within substructures. In addition, damage severity was treated in this paper since it is worthy to know damage severity. Optimization technique is used to estimate damage level using measured responses and damage model. Two test examples, a plate and a jointed structure, are chosen to verify the suggesting method.

• Journal of Power Electronics
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• v.10 no.6
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• pp.702-708
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• 2010

In this paper, a fault diagnosis algorithm for brushless DC (BLDC) motor drives is proposed to maintain control performance under switch open-damage. The proposed fault diagnosis algorithm consists of a simple algorithm using measured phase current information and it detects open-circuit faults based on the operating characteristic of BLDC motors. The proposed algorithm quickly recovers control performance due to its short detection time and its reconfiguration of the system topology. It can be embedded into existing BLDC drive software as a subroutine without additional sensors. The feasibility of the proposed fault diagnosis algorithm is proven by simulation and experimental results.

• Advances in aircraft and spacecraft science
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• v.9 no.2
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• pp.149-167
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• 2022

A Modified fuzzy mechanical control of large-scale multiple time delayed dynamic systems in states is considered in this paper. To do this, at the first level, a two-step strategy is proposed to divide a large system into several interconnected subsystems. And we focus on the damage propagation for aircraft structural analysis of composite materials. As a modified fuzzy control command, the next was received as feedback theory based on the energetic function and the LMI optimal stability criteria which allow researchers to solve this problem and have the whole system in asymptotically stability. And we focus on the results which shows the high effective by the proposed theory utilized for damage propagation for aircraft structural analysis of composite materials.

• Structural Engineering and Mechanics
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• v.18 no.3
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• pp.287-301
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• 2004

Structural acceleration regulation is a means of managing structural response energy and enhancing the performance of civil structures undergoing large seismic events. A quadratic output regulator that minimizes a measure including the total structural acceleration energy is developed and tested on a realistic non-linear, semi-active structural control case study. Suites of large scaled earthquakes are used to statistically quantify the impact of this type of control in terms of changes in the statistical distribution of controlled structural response. This approach includes the impulses due to control inputs and is shown to be more effective than a typical displacement focused control approach, by providing equivalent or better performance in terms of displacement and hysteretic energy reductions, while also significantly reducing peak story accelerations and the associated damage and occupant injury. For earthquake engineers faced with the dilemma of balancing displacement and acceleration demands this control approach can significantly reduce that concern, reducing structural damage and improving occupant safety.

• 제어로봇시스템학회:학술대회논문집
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• 2002.10a
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• pp.32.6-32
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• 2002

The damage localization of the structural system using the natural frequency measurement only is proposed. The existing methods use the changes of mode shape, strain mode shape or curvature mode shape before and after the damage occurrence as these shapes carry the geometric information of the structure. Basically, the change of natural frequencies of the structure can be used as the indicator of the damage occurrence but not as the indicator of the damage location as the natural frequency changes does not carry the geometric information of the structure. In this research, the feedback scope method that measures the natural frequency changes of the structure with and without the feedback Ioo...

• Spatial Information Research
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• v.10 no.4
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• pp.493-499
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• 2002

This paper presents the disaster control due to flooding through the case study of Samwhadong, Donghae city, Kangwondo, broken out at 31, August 2002. In order to assess the characteristics of flood damage one must consider social and geological conditions, the factors of flood risk were derived based on GIS. For reduction of flood damage, flood hazard map was prepared for local residents. These information will support refuge activities, it would aid the reduction of flood damage.