• Journal of the Korean Geotechnical Society
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• v.38 no.12
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• pp.91-101
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• 2022

The 1995 Kobe earthquake caused a massive damage to the Port of Kobe. Therefore, it was pointed out that it was impossible to design port structures for Level II (Mw 6.5) earthquakes with quasi-static analysis and Allowable Stress Design methods. In Japan and the United States, where earthquakes are frequent, the most advanced design standards for port facilities are introduced and applied, and the existing seismic design standards have been converted to performance-based design. Since 1999, the Korean Port Seismic Design Act has established a definition of necessary facilities and seismic grades through research on facilities that require seismic design and their seismic grades. It has also established a performance-based seismic design method based on experimental verification. In the performance-based seismic design method of the breakwater proposed in this study, the acceleration time history on the surface of the original ground was subjected to a fast Fourier transform, followed by a filter processing that corrected the frequency characteristics corresponding to the maximum allowable displacement with respect to performance level of the breakwater and the filtered spectrum. The horizontal seismic coefficient for the equivalent static analysis considering the displacement was calculated by inversely transforming (i.e., subjected to an inverse fast Fourier transform) into the acceleration time history and obtaining the maximum acceleration value. In addition, experiments and numerical analysis were performed to verify the performance-based seismic design method of breakwaters suitable for domestic earthquake levels.

• The Korea Journal of Herbology
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• v.29 no.2
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• pp.39-45
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• 2014

Objectives : The purpose of this study was to investigate antiaging and antioxidant effects on cultured human skin fibroblast with 80% ethanol extracts of plants including of stem of Dendropanax morbifera, Corni fructus and Lycii Fructus. Methods : An ethanol extract of three medicinal plants including stem of Dendropanax morbifera, Corni fructus and Lycii Fructus. Extracts were assessed to determine the mechanism of antioxidant and antiaging activities. Antioxidant activity of extract was evaluated by two different assays as 2,2-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and super oxide dismutase (SOD) like activities. These extracts were tested for cell viability on HS68 skin fibroblast by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay. We investigated the effects of Ultraviolet-B irradiation on cytotoxicity, type 1 collagen, elastin level and oxidative damage in cultured human skin fibroblast (HS68). Recently, many studies have reported that elastin is also involved in inhibiting or repairing wrinkle formation, although collagen is a major factor in the skin wrinkle formation. Results : The extracts obtained dose-dependently increased the scavenging activity on DPPH radical scavenging activity and SOD like activity. The extracts of complex herbal medicine showed low cytotoxicity as more than 100% cell viability in 100ppm/ml concentration. HS68 fibroblasts were survived 70% at 120 $mJ/cm^2$ UVB irradiation and treated tumor necrosis factor (TNF)-alpha. The levels of aging factors and cytotoxicity were decreased by ethanol extract of complex herbal medicine. Conclusions : These results suggest that ethanol extracts of complex medicinal plants of including of stem of Dendropanax morbifera, Corni fructus and Lycii Fructus may have value as the potential antioxidant and antiaging medicinal plant.

• Journal of Digital Convergence
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• v.20 no.2
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• pp.9-20
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• 2022

Supply chain attacks target critical infrastructure, causing large amounts of damage and evolving into a threat to public safety and national security. Accordingly, when establishing cybersecurity strategies and policies, supply chain risk management is specified to enhance security, and the US Biden administration recently issued the Executive Order on Improving the Nation's Cybersecurity, SBOM was mentioned as part of the guidelines for strengthening software supply chain security. If the government mandates SBOM and uses it as a security verification tool for supply chains, it can be affected by the domestic procurement system in the future and can be referenced when establishing a security system for domestic supply chains according to the progress of policy implementation. Accordingly, in this paper, countries that are promoting the SBOM policy as a way to strengthen the security of the software supply chain were selected and analyzed with a focus on related cases. In addition, through comparison and analysis of foreign SBOM policy trends, methods for using domestic SBOM in terms of technology, policy, and law were considered. As the value of using SBOM as a supply chain integrity/transparency verification tool is expected in the future, it is necessary to continuously identify trends in the establishment of international standardization and policy development for SBOM and study the standard format.

• Journal of Practical Engineering Education
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• v.14 no.1
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• pp.119-125
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• 2022

Materials used for education are materials such as SM20C, Al6061, and acrylic. SM20C materials are carbon steel and are often used in certification tests and functional competitions, but are also widely used in industrial sites. The Al6061 material is said to be a material that has lower hardness and stronger flexibility than carbon steel, so it is a material that generates a lot of compositional selection of tools. If students are taught practical training using acrylic materials, vibration occurs due to excessive cutting in some parts and damage to the tool occurs. In this process, we examine to what extent the impact on the 2NC head, which is a five-axis equipment, can affect precision control. The weakest part of the five-axis equipment can be said to be the weakest part of the head that controls the AC axis. When the accuracy and cumulative tolerance of this part occur, the accuracy of all products decreases. Therefore, the core part of the 2NC head, the spindle housing, was carried out using an Al7075 T6 (Alcoa, USA) material. In the process of vibration and cutting applied to this material, the analysis was conducted to find out the value applied to the finite element analysis under extreme conditions. It is hoped that this analysis data will help students see and understand the structure of 5-axis machining rather than 5-axis cutting.

• Explosives and Blasting
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• v.40 no.4
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• pp.15-26
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• 2022

With the recent increase in old and dangerous buildings, the demand for technology in the field of structure demolition is rapidly increasing. In particular, in the case of structures with severe deformation of damage, there is a risk of deterioration in stability and disaster due to changes in the load distribution characteristics in the structure, so rapid structure demolition technology that can be efficiently dismantled in a short period of time is drawing attention. However, structural deformation such as unauthorized extension or illegal remodeling occurs frequently in many old structures, which is not reflected in structural information such as building drawings, and acts as an obstacle in the demolition design process. In this study, as an effective way to overcome the discrepancy between the structural information of old structures and the actual structure, access to actual structures through 3D modeling was considered. 3D point cloud data inside and outside the building were obtained through LiDAR and drone photography for buildings scheduled to be blasting demolition, and precision matching between the two spatial data groups was performed using an open-source based spatial information construction system. The 3D structure model was completed by importing point cloud data matched with 3D modeling software to create structural drawings for each layer and forming each member along the structure slab, pillar, beam, and ceiling boundary. In addition, the modeling technique proposed in this study was verified by comparing it with the actual measurement value for selected structure member.

• Journal of Ginseng Research
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• v.47 no.2
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• pp.337-346
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• 2023

Background: Ginsenoside Rb2, a major active component of Panax ginseng, has various physiological activities, including anticancer and anti-inflammatory effects. However, the mechanisms underlying the rejuvenation effect of Rb2 in human skin cells have not been elucidated. Methods: We performed a senescence-associated β-galactosidase staining assay to confirm cellular senescence in human dermal fibroblasts (HDFs). The regulatory effects of Rb2 on autophagy were evaluated by analyzing the expression of autophagy marker proteins, such as microtubule-associated protein 1A/1B-light chain (LC) 3 and p62, using immunoblotting. Autophagosome and autolysosome formation was monitored using transmission electron microscopy. Autophagic flux was analyzed using tandem-labeled GFP-RFP-LC3, and lysosomal function was assessed with Lysotracker. We performed RNA sequencing to identify potential target genes related to HDF rejuvenation mediated by Rb2. To verify the functions of the target genes, we silenced them using shRNAs. Results: Rb2 decreased β-galactosidase activity and altered the expression of cell cycle regulatory proteins in senescent HDFs. Rb2 markedly induced the conversion of LC3-I to LC3-II and LC3 puncta. Moreover, Rb2 increased lysosomal function and red puncta in tandem-labeled GFP-RFP-LC3, which indicate that Rb2 promoted autophagic flux. RNA sequencing data showed that the expression of DNA damage-regulated autophagy modulator 2 (DRAM2) was induced by Rb2. In autophagy signaling, Rb2 activated the AMPK-ULK1 pathway and inactivated mTOR. DRAM2 knockdown inhibited autophagy and Rb2-restored cellular senescence. Conclusion: Rb2 reverses cellular senescence by activating autophagy via the AMPK-mTOR pathway and induction of DRAM2, suggesting that Rb2 might have potential value as an antiaging agent.

• Journal of the Korean Society of Radiology
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• v.17 no.2
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• pp.249-255
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• 2023

In this study, radiation exposure doses were measured in the course of clinical practice of radiation workers, radiological technologists in the radiation-related worker group, and preliminary-radiological technologists who were classified as frequent visitors. Radiological technologists who worked in the radiation area of C University Hospital in Incheon for a year from January 2021 and 121 students who completed clinical practice at the same medical institution from July 1 to August 31 were the subjects of the study. The nominal risk factor based on ICRP 103 was used to evaluate the probability of side effects due to the exposure dose to the lungs, which are organs at risk of damage due to radiation exposure dose. During the clinical practice period, radiology students, who were classified as frequent visitors, had a surface dose of 0.98 ± 0.14 mSv and a deep dose of 0.93 ± 0.14 mSv. In other words, 6.7 per 1,000,000 for shallow dose and 6.4 per 1,000,000 for deep dose were found to have side effects due to exposure to the lungs. This is a value in terms of exposure dose in one year. Considering that the radiation (science) education course is 3 or 4 years, systematic management and attention to prospective radiation workers who are going to clinical practice are required, and the stochastic effect of radiation In relation to this, it is considered that it will be used as basic data for radiation safety management.

• Journal of the Korean Society of Marine Environment & Safety
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• v.29 no.5
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• pp.445-455
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• 2023

Sea level rise due to global warming is accelerating. According to the IPCC survey, the expected sea level rise in 2100 was analyzed to be 47cm in the low-carbon scenario (SSP 1-2.6) and 82cm in the high-carbon scenario (SSP 5-8.5). Sea level rise can cause serious damage to port infrastructure and reduce the safety of ships docked inside ports. In this study, Mokpo Port, which frequently suffers from flooding during high tide, was selected and the sensitivity of mooring evaluation factors was analyzed for actual berthing ships according to sea level rise scenarios. From the analysis, we found that the tension of mooring line, the load of bollard, vertical angle of mooring line, and ship's motion of 6-DOF, which are evaluation factors, generally increased when the sea level increased. The most sensitive evaluation factor was sway motion of 6-DOF. Also, we analyzed that the value of mooring evaluation factors decreased when the crown height was raised. This was beneficial in improving ship and pier safety. The results of this study can be used as basic data to secure measures to improve port and ship safety according to sea level rise in Mokpo Port.

• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.685-690
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• 2023

It was analyzed that the volume of deep excavation works adjacent to existing underground structures is increasing according to the population growth and density of cities. Currently, many underground structures and tracks are damaged by external factors, and the cause is analyzed based on the measurement results in the tunnel, and measurements are being made for post-processing, not for prevention. The purpose of this study is to analyze the effect on the deformation of the structure due to the excavation work adjacent to the urban railway track in use. In addition, the safety of structures is evaluated through machine learning techniques for displacement of structures before damage and destruction of underground structures and tracks due to external factors. As a result of the analysis, it was analyzed that the model suitable for predicting the structure management standard value time in the analyzed dataset was a polynomial regression machine. Since it may be limited to the data applied in this study, future research is needed to increase the diversity of structural conditions and the amount of data.

• Journal of the Korean Geotechnical Society
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• v.23 no.11
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• pp.87-98
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• 2007

For the quick rehabilitation of a fire-damaged tunnel structure, it is the most important procedure to investigate the fire-induced damaged zone rapidly. This study aims to propose a new drilling resistance testing method by which mechanical properties of tunnel concrete lining altered by high temperature can be estimated easily and continuously. Especially, it alms to derive the relationships to estimate mechanical properties of mortar and concrete materials from drilling parameters. To obtain the optimum testing condition, a series of drilling resistance tests were carried out for mortar specimens. When the rotation per minute of drill bit, tile penetration rate and the bit diameter were 1,300 rpm, 1.40 mm/sec, and 10 mm respectively, the deviation of measured drilling resistance forces was minimal. Under the optimum testing condition, the relationships between drilling resistance and mechanical properties of mortar specimens were shown to be very favorable. The concept of replacing a mean value of resistance farces measured during drilling with the resistance energy was proposed to consider the effects of randomly distributed aggregates inside a concrete material on drilling resistance. When the concept was applied to concrete materials, a favorable relationship between actual compressive strength and drilling resistance energy was also successfully derived.