• 한국농공학회논문집
• /
• 제61권4호
• /
• pp.75-86
• /
• 2019

Recently, natural disasters due to abnormal climates are frequently outbreaking, and there is rapid increase of damage to aged agricultural infrastructure. As agricultural infrastructure facilities are in contact with water throughout the year and the number of them is significant, it is important to build a maintenance management system. Especially, the current maintenance management system of pumping and drainage stations among the agricultural facilities has the limit of lack of objectivity and management personnel. The purpose of this study is to develop a performance evaluation model using the factors related to performance degradation of pumping and drainage facilities and to predict the performance of the facilities in response to climate change. In this study, we focused on the pumping and drainage stations belonging to each climatic zone separated by the Korea geographical climatic classification system. The performance evaluation model was developed using three different statistical models of POLS, RE, and LASSO. As the result of analysis of statistical models, LASSO was selected for the performance evaluation model as it solved the multicollinearity problem between variables, and showed the smallest MSE. To predict the performance degradation due to climate change, the climate change response variables were classified into three categories: climate exposure, sensitivity, and adaptive capacity. The performance degradation prediction was performed at each facility using the developed performance evaluation model and the climate change response variables.

• 대한토목학회논문집
• /
• 제39권2호
• /
• pp.263-272
• /
• 2019

본 연구는 실제 고속도로 인접지역에서 발생한 토석류를 대상으로 고속도로에서의 토석류 거동을 FLO-2D 모형을 적용하여 재현함으로써, 고속도로에서의 토석류 영향 해석에 대한 FLO-2D 모형의 활용성을 검증하고자 하였다. 대상유역으로는 2005년 8월 집중호우로 토석류가 발생하여 24시간 동안 교통이 차단된 대전-진주간 고속도로의 덕유산 휴게소구간으로 선정하였다. 발생 토석류에 대한 현장조사 및 토성 시험분석 자료를 활용하여 GIS를 이용한 지형분석, HEC-HMS를 이용한 수문분석, 그리고 토석량을 산정하였다. 그리고 나서 FLO-2D 모형의 매개변수 민감도 분석을 통한 최적 매개변수 조합을 선정한 후, FLO-2D 모형을 적용한 토석류 거동해석을 수행하였다. 모형의 예측치와 실측자료와의 비교 분석을 통하여 고속도로에서 토석류 거동해석을 위한 FLO-2D 활용 가능성을 보여주었다.

• Nuclear Engineering and Technology
• /
• 제53권10호
• /
• pp.3236-3246
• /
• 2021

Lessons learned from the Fukushima Daiichi nuclear power plant accident directed that multiple failures should be considered more seriously rather than single failure in the licensing bases and safety cases because attempts to take accident management measures could be unsuccessful under the high radiation environment aggravated by multiple failures, such as complete loss of electric power, uncontrollable loss of coolant inventory, failure of essential safety function recovery. In the case of the complete loss of electric power called station blackout (SBO), if there is no mitigation action for recovering safety functions, the reactor core would be overheated, and severe fuel damage could be anticipated due to the failure of the active heat sink. In such a transient condition at CANDU-6 plants, the seal failure of the primary heat transport (PHT) pumps can facilitate a consequent increase in the fuel sheath temperature and eventually lead to degradation of the fuel integrity. Therefore, it is necessary to specify the regulatory guidelines for multiple failures on a licensing basis so that licensees should prepare the accident management measures to prevent or mitigate accident conditions. In order to explore the efficiency of implementing accident management strategies for CANDU-6 plants, this study proposed a realistic accident analysis approach on the SBO transient with multiple-failure sequences such as seal failure of PHT pumps without operator's recovery actions. In this regard, a comparative study for two PHT pump seal failure modes with and without coolant seal leakage was conducted using a best-estimate code to precisely investigate the behaviors of thermal-hydraulic parameters during transient conditions. Moreover, a sensitivity analysis for different PHT pump seal leakage rates was also carried out to examine the effect of leakage rate on the system responses. This study is expected to provide the technical bases to the accident management strategy for unmitigated transient conditions with multiple failures.

• Journal of Microbiology and Biotechnology
• /
• 제29권10호
• /
• pp.1522-1542
• /
• 2019

To adapt to environmental changes and to maintain cellular homeostasis, microorganisms adjust the intracellular concentrations of biochemical compounds, including metal ions; these are essential for the catalytic function of many enzymes in cells, but excessive amounts of essential metals and heavy metals cause cellular damage. Metal-responsive transcriptional regulators play pivotal roles in metal uptake, pumping out, sequestration, and oxidation or reduction to a less toxic status via regulating the expression of the detoxification-related genes. The sensory and regulatory functions of the metalloregulators have made them as attractive biological parts for synthetic biology, and the exceptional sensitivity and selectivity of metalloregulators toward metal ions have been used in heavy metal biosensors to cope with prevalent heavy metal contamination. Due to their importance, substantial efforts have been made to characterize heavy metal-responsive transcriptional regulators and to develop heavy metal-sensing biosensors. In this review, we summarize the biochemical data for the two major metalloregulator families, SmtB/ArsR and MerR, to describe their metal-binding sites, specific chelating chemistry, and conformational changes. Based on our understanding of the regulatory mechanisms, previously developed metal biosensors are examined to point out their limitations, such as high background noise and a lack of well-characterized biological parts. We discuss several strategies to improve the functionality of the metal biosensors, such as reducing the background noise and amplifying the output signal. From the perspective of making heavy metal biosensors, we suggest that the characterization of novel metalloregulators and the fabrication of exquisitely designed genetic circuits will be required.

• 한국정보통신학회논문지
• /
• 제23권12호
• /
• pp.1535-1541
• /
• 2019

방사선 사고 지역 및 제염이 필요한 지역에서의 안전하고 신속한 제염작업을 진행하기 위해서는 방사선 오염원에 대한 다양한 정보 획득이 필요하다. 특히 방사선원의 정확한 위치와 분포 정보의 파악은 신속한 후속 조치 및 오염원 제거를 위해 반드시 필요하며, 작업자의 방사선 피폭을 최소화할 수 있다. 방사선원의 위치와 분포 정보를 획득하기 위해서는 방사선 분포 탐지 장치를 사용한다. 방사선 분포 탐지 장치의 경우 일반적으로 탐지 센서 부가 단일 센서로 구성되며, 단일 센서의 물리적 한계로 인해 탐지 범위가 제한되는 문제점이 있다. 본 논문에서는 방사선 오염 분포 영상화 장치에 사용되는 단일 센서의 탐지 감도 제어를 위하여 보정 검출기를 적용하였으며, 이를 통해 제한적이었던 선량률 탐지 범위를 향상하였다. 또한 감마선 조사 시험을 통해 방사선 분포 탐지 범위의 개선을 확인하였다.

• Current Optics and Photonics
• /
• 제6권2호
• /
• pp.143-150
• /
• 2022

Anti-resonant hollow-core photonic crystal fiber (AR-HCF) has unique advantages, such as low nonlinearity and high damage threshold, which make it a promising candidate for high-power laser delivery at distances of tens of meters. However, due to the special structure, optical properties such as mode-field profile and bending loss of hollow-core fibers are different from those of solid-core fibers. These differences have limited the widespread use of AR-HCF in practice. In this paper we conduct numerical analysis of AR-HCFs with different structural parameters, to analyze their influences on an AR-HCF's optical properties. The simulation results show that with a 23-㎛ air-core diameter, the fundamental mode profile of an AR-HCF can well match that of the widely used Nufern's 20/400 fiber, for nearly-single-mode power delivery applications. Moreover, with the ratio of cladding capillary diameter to air-core diameter ranging from 0.6 to 0.7, the AR-HCF shows excellent optical characteristics, including low bending sensitivity while maintaining single-mode transmission at the same time. We believe these results lay the foundation for the application of AR-HCFs in the power delivery of high power fiber laser systems.

• Smart Structures and Systems
• /
• 제29권3호
• /
• pp.445-455
• /
• 2022

Steel anchor bolts are installed in concrete using a variety of methods. One of the most common methods of anchor bolt installation is using epoxy resin as an infill material injected into the drilled hole to act as a bonding material between the steel bolt and the surrounding concrete. Typical design standards assume uniform stress distribution along the length of the anchor bolt accompanied with single crack leading to pull-out failure. Experimental evidence has shown that the steel anchor bolts fail owing to the multiple failure patterns, hence these design assumptions are not realistic. In this regard, the presented research work details the analytical model that takes into consideration multiple micro cracks in the infill material induced via impact loading. The impact loading from the Schmidt hammer is used to evaluate the bond condition bond condition of anchor bolt and the epoxy material. The added advantage of the presented analytical model is that it is able to take into account the various type of end conditions of the anchor bolts such as bent or U-shaped anchors. Through sensitivity analysis the optimum stiffness and shear strength properties of the epoxy infill material is achieved, which have shown to achieve lower displacement coupled with reduced damage to the surrounding concrete. The accuracy of the presented model is confirmed by comparing the simulated deformational responses with the experimental evidence. From the comparison it was found that the model was successful in simulating the experimental results. The proposed model can be adopted by professionals interested in predicting and controlling the deformational response of anchor bolts.

• Restorative Dentistry and Endodontics
• /
• 제48권2호
• /
• pp.12.1-12.11
• /
• 2023

Objectives: The present study evaluated the pulp response of human mandibular incisors subjected to in-office dental bleaching using gels with medium or high concentrations of hydrogen peroxide (HP). Materials and Methods: The following groups were compared: 35% HP (HP35; n = 5) or 20% HP (HP20; n = 4). In the control group (CONT; n = 2), no dental bleaching was performed. The color change (CC) was registered at baseline and after 2 days using the Vita Classical shade guide. Tooth sensitivity (TS) was also recorded for 2 days post-bleaching. The teeth were extracted 2 days after the clinical procedure and subjected to histological analysis. The CC and overall scores for histological evaluation were evaluated by the Kruskal-Wallis and Mann-Whitney tests. The percentage of patients with TS was evaluated by the Fisher exact test (α = 0.05). Results: The CC and TS of the HP35 group were significantly higher than those of the CONT group (p < 0.05) and the HP20 group showed an intermediate response, without significant differences from either the HP35 or CONT group (p > 0.05). In both experimental groups, the coronal pulp tissue exhibited partial necrosis associated with tertiary dentin deposition. Overall, the subjacent pulp tissue exhibited a mild inflammatory response. Conclusions: In-office bleaching therapies using bleaching gels with 20% or 35% HP caused similar pulp damage to the mandibular incisors, characterized by partial necrosis, tertiary dentin deposition, and mild inflammation.

• Nuclear Engineering and Technology
• /
• 제55권12호
• /
• pp.4367-4381
• /
• 2023

Nuclear power plants are increasingly being equipped with digital I&C systems. Although some probabilistic safety assessment (PSA) models for the digital I&C of nuclear power plants have been constructed, there is currently no specific internationally agreed guidance for their modeling. This paper presents an initiative by the OECD Nuclear Energy Agency called "Digital I&C PSA - Comparative application of DIGital I&C Modelling Approaches for PSA (DIGMAP)", which aimed to advance the field towards practical and defendable modeling principles. The task, carried out in 2017-2021, used a simplified description of a plant focusing on the digital I&C systems important to safety, for which the participating organizations independently developed their own PSA models. Through comparison of the PSA models, sensitivity analyses as well as observations throughout the whole activity, both qualitative and quantitative lessons were learned. These include insights on failure behavior of digital I&C systems, experience from models with different levels of abstraction, benefits from benchmarking as well as major contributors to the core damage frequency and those with minor effect. The study also highlighted the challenges with modeling of large common cause component groups and the difficulties associated with estimation of key software and common cause failure parameters.

• 대한핵의학회지
• /
• 제33권5호
• /
• pp.439-451
• /
• 1999

목적: 안구 내 종양의 치료계획에 있어서 악성여부의 결정은 매우 중요하다. 하지만 안구 내 종양의 생검은 시력의 손상을 가져오므로 임상적으로 권장할 수 없는 방법이다. 저자들은 안구 네 종양의 악성 여부를 진단하는 데 있어서 F-18-FDG PET의 유용성과 검사 방법이 결과에 미치는 영향에 대해 연구하였다. 대상 및 방법: 임상적으로 악성 안구 내 종양이 의심되는 13명의 환자(15병소)를 대상으로 F-18-FDG PET 스캔을 시행하였다. 세 명은 양성의 병소를 가지고 있었고(망막 박리, 맥락막 삼출, 맥락막출혈) 열 명을 열두 개의 악성 병소를 가지고 있었다(흑색종 3, 망막아종 7, 전이암 2). 양성 병소들과 악성 병소들의 크기는 각각 $164{\pm}85mm^3$과 $598{\pm}718mm^3$이었다. 영상은 GE Advance PET 스캐너(전체반값두께 4.6 mm)를 이용하여 얻었다. 각각의 영상에 대해 매트릭스 크기를 바꾸어 가면서($256{\times}256$과 $128{\times}128$) 감쇠보정을 하거나 하지 않는 두 가지방법으로 재구성하여 재구성 방법에 의한 영향을 비교하였다. 여덟 명의 환자(양성 3, 악성 병소 6)에서 추가로 전신스캔을 시행하였다. 육안 판독 후 반정량적으로 분석하여 표준섭취계수를 구하여 분석하였다. 결과: 치료하지 않은 악성 병소는 모두 진단할 수 있었고 양성 병소는 육안적으로 관찰되지 않았다. 10개의 악성 병소들의 픽셀당 최대 표준섭취 계수는 $2.64{\pm}0.57g/ml$로 한 예를 제외하고는 모두 2.0 g/ml보다 높았다. 종양의 크기와 표준섭취계수는 통계적인 상관관계가 없었다. 전신스캔에서는 두개의 $1000 mm^3$ 보다 큰 악성 병소는 높은 섭취를 보였으나 중간 크기의 병소들은 희미하게 관찰되었고 $100 mm^3$ 이하의 병소 두 개는 관찰되지 않았다. 결론: F-18-FDG PET는 안구 내 악성 종양의 진단에 있어서 높은 예민도를 보여 주었다. 악성 종양은 모두 육안적으로 진단할 수 있었다. 작은 크기의 안구 내 종양을 진단하기 위해서는 전신스캔은 예민도가 낮아 적당하지 않고 스캔시간을 충분히 길게 하여 안구 국소촬영을 할 필요가 있다. 영상은 $128{\times}128$ 매트릭스보다 $256{\times}256$ 매트릭스로 재구성하는 것이 좋다.