• Title/Summary/Keyword: cycle time (CT)

Search Result 49, Processing Time 0.026 seconds

Two Cases of Non-Small Cell Lung Cancer Treated with Intravenous Cultivated Wild Ginseng Pharmacopuncture (산삼약침 혈맥주입을 시행한 비소세포성폐암 환자 2례)

  • Bang, Sun-Hwi;Kwon, Ki-Rok;Yoo, Hwa-Seung
    • Journal of Pharmacopuncture
    • /
    • v.11 no.2
    • /
    • pp.13-19
    • /
    • 2008
  • Objectives To investigate the therapeutic effects of intravenous cultivated wild ginseng(Panax ginseng C.A. Meyer) pharmacopuncture(CWGP) in treating patients with non-small cell lung cancer(NSCLC). Design Prospective case series. Setting This study was conducted at the East-West Cancer Center of Dunsan Oriental Hospital, Daejeon University. Patients Two non-small cell lung cancer patients. Intervention Two non-small cell lung cancer patients were injected CWGP(20mL/day) mixed with 0.9% normal saline(100mL) intravenously. Each patient received a total of 16 and 9 cycles, respectively. One cycle is composed of 14 days. Outcome Measures The effect of intravenous CWGP was measured by scanning with computed tomography(CT) after every 2 cycle and Positron emission tomography- computed tomography(PET/CT) after every 6 cycles. Response and progression was evaluated using the Response Evaluation Criteria in Solid Tumors(RECIST) Committee classification of complete response(CR), partial response(PR), progressive disease(PD) and stable disease(SD). Results They were treated with intravenous CWGP for 8 and 5 months respectively. time later, each tumor remains stable disease(SD). Conclusion These cases may give us a possibility that intravenous CWGP offers potential benefits for non-small cell lung cancer patients.

Quay Crane Dual-cycle Plan considering Yard Tractor waiting time (야드 트랙터 대기시간을 고려한 크레인 듀얼 사이클 계획)

  • Chung, Chang-Yun;Shin, Jae-Young
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
    • /
    • 2009.10a
    • /
    • pp.220-221
    • /
    • 2009
  • One of the important performance measure for productivity at container terminals is the working productivity in the quay. working scheduling of quay cranes (QCs) gives a significant impact on the quay working productivity. The recent managers of the terminals pay high interests in equipment investment and operation methods with a new concept in order to enhance the quay working productivity. The double cycle or dual cycle, which is a method to increase the quay productivity with no application of new equipment, but with the change of operations, has been received strong attention in academic research. The majority of studies until this time has been realized the quay work as the bottleneck and focused on those works. However, if the QCs do notver, it the Cs d-trotver,(CT) if t the Cs, there would be the pos ibilf tes that the effectiveness of them is decreasedveaused by the longer, if t the Cs. Thus, this paper, suggests the solutions on the con th scheduling for the dual cycle operation considering the YT.

  • PDF

A Design Method of Iron-cored CTs To Prevent Satruation (포화를 방지하기 위한 보호용 철심 변류기 설계 방법)

  • Lee, Ju-Hun;Gang, Sang-Hui;Gang, Yong-Cheol;Lee, Seung-Jae;Bae, Ju-Cheon;An, Jun-Gi;Lee, Cheong-Hak;Lee, Jeong-Taek
    • The Transactions of the Korean Institute of Electrical Engineers A
    • /
    • v.48 no.2
    • /
    • pp.119-126
    • /
    • 1999
  • Current transformer (CT) saturation may cause a variety of protective relays to malfunction. The conventional CT is designed that it can carry up to 20 times the rated current without exceeding 10% ratio error. However, the possibility of CT saturation still remains if the fault current contains substantial amounts of ac and/or dc components. This paper presents a design method of iron-cored CTs for use with protective relays to prevent CT saturation. The proposed design method determines the core cross section of the CT; it employs the transient dimensioning factor to consider relay's operating time (duty cycle) and dc component as well as ac components contained in the fault current, and symmetrical short-circuit current factor to consider as well as ac components contained in the fault current, and symmetrical short-circuit current factor to consider the biggest fault current. The method designs the cross section of CTs in cases of reclosure and no reclosure.

  • PDF

Effectiveness of the Respiratory Gating System for Stereotectic Radiosurgery of Lung Cancer (폐암 환자의 정위적 방사선 수술 시 Respiratory Gating System의 유용성에 대한 연구)

  • Song Heung-Kwon;Kwon Kyung-Tae;Park Cheol-Su;Yang Oh-Nam;Kim Min-Su;Kim Jeong-Man
    • The Journal of Korean Society for Radiation Therapy
    • /
    • v.17 no.2
    • /
    • pp.125-131
    • /
    • 2005
  • Purpose : For stereotactic radiosurgery (SRS) of a tumor in the region whose movement due to respiration is significant, like Lung lower lobe, the gated therapy, which delivers radiation dose to the selected respiratory phases when tumor motion is small, was performed using the Respiratory gating system and its clinical effectiveness was evaluated. Materials and Methods : For two SRS patients with a tumor in Lung lower lobe, a marker block (infrared reflector) was attached on the abdomen. While patient' respiratory cycle was monitored with Real-time Position Management (RPM, Varian, USA), 4D CT was performed (10 phases per a cycle). Phases in which tumor motion did not change rapidly were decided as treatment phases. The treatment volume was contoured on the CT images for selected treatment phases using maximum intensity projection (MIP) method. In order to verify setup reproducibility and positional variation, 4D CT was repeated. Results : Gross tumor volume (GTV) showed maximum movement in superior-inferior direction. For patient #1, motion of GTV was reduced to 2.6 mm in treatment phases ($30{\sim}60%$), while that was 9.4 mm in full phases ($0{\sim}90%$) and for patient #2, it was reduced to 2.3 mm in treatment phases ($30{\sim}70%$), while it was 11.7 mm in full phases ($0{\sim}90%$). When comparing two sets of CT images, setup errors in all the directions were within 3 mm. Conclusion : Since tumor motion was reduced less than 5 mm, the Respiratory gating system for SRS of Lung lower lobe is useful.

  • PDF

Use of Real-Time PCR and Internal Standard Addition Method for Identifying Mixed Ratio of Chicken Meat in Sausages (Real-Time PCR과 Internal Standard Addition법을 이용한 돼지고기 소시지에 혼합된 닭고기의 정량)

  • Lee, Namrye;Joo, Jae-Young;Yeo, Yong-Heon
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.46 no.9
    • /
    • pp.1097-1105
    • /
    • 2017
  • This study examined how much chicken meat was in sausage made with pork. Both real-time polymerase chain reaction (PCR) and internal standard addition were used. Fifty ng of chicken DNA was added to the sausages as an internal standard. The addition of standard DNA increased the amplification efficiency of PCR and confirmed the possibility of quantitative analysis. A QIAamp DNA Micro Kit was used to improve the DNA recovery and amplification efficiency. The density of template DNA and primer were suitable for $3.0{\sim}5.0{\mu}L$ and $0.5{\mu}L$, respectively. Each DNA of pig and chicken was diluted in 10-fold from steps 50 ng to 0.05 ng. The detection limit of both pig and chicken meat was more than 0.05 ng and the correlation coefficient of the standard curve was at least 0.98. The result of the quantitative analysis after heat treatment of 3 samples of pigs and chickens mixed at 70:30 showed a 5.7% difference (64.3:35.7) between the expected value and measured value. The quantitative value was changed by affecting the DNA according to the heat treatment ($70^{\circ}C$, 10 min). An analysis of the pork and chicken content in sausages showed that it was difficult to detect chicken meat and the quantitative value of DNA according to the Ct value was very low. On the other hand, when adding standard material (50 ng of chicken DNA) to the sausages, the Ct value decreased gradually with increasing chicken mixing ratio. Thus, the mixing ratio of chicken in sausages could be estimated.

A Study on the Specific Fuel Consumption of the Farm Kerosene Engines (농업용 석유기관의 연료소비율에 관한 연구)

  • 신건성
    • Magazine of the Korean Society of Agricultural Engineers
    • /
    • v.17 no.2
    • /
    • pp.3763-3771
    • /
    • 1975
  • This study was attempted to investigate the changes of specific fuel consumption, compression pressure and power output, consequently to obtain basic data on farm kerosene engine. The samples which are used in this study are a 4 cycle water cooled korosene engine for the use of K6-CT83 power tiller and a 4 cycle air-cooled kerosene engine for the use of G5L-3A water pump. The Korean Industrial Standards (K.S)KS-B 6002 "Test code of small internal combustion engine" was referred in carrying out this study, and its results are as follows. 1. According to load increasing, the speific fuel consumption of the engines generally decreases, however, in case of 10% over-loading it increases. 2. As a result of full load consecutive operation, according to passing of operating time, the amount of wear generally increases, consequently the speific fuel consumption also increases, and inversly the compression pressure decreases. 3. The changes of specific fuel consumption and compression pressure were closely related with time of piston ring exchange, and periodically about 100 hours the engines show the increase of specific fuel consumption and the decrease of compression pressure. 4. After about 300 hours, although the engine had new piston rings, the specific fuel consumption increase, consequently the engine needs boring. In actual use, it is impossible to operate consecutively on full load, therefore the boring time of engine is expected to come later.

  • PDF

Cancer/Testis OIP5 and TAF7L Genes are Up-Regulated in Breast Cancer

  • Mobasheri, Maryam Beigom;Shirkoohi, Reza;Modarressi, Mohammad Hossein
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.11
    • /
    • pp.4623-4628
    • /
    • 2015
  • Breast cancer still remains as the most frequent cancer with second mortality rate in women worldwide. There are no validated biomarkers for detection of the disease in early stages with effective power in diagnosis and therapeutic approaches. Cancer/testis antigens are recently promising tumor antigens and suitable candidates for targeted therapies and generating cancer vaccines. We conducted the present study to analyze transcript changes of two cancer/testis antigens, OIP5 and TAF7L, in breast tumors and cell lines in comparison with normal breast tissues by quantitative real time RT-PCR for the first time. Significant over-expression of OIP5 was observed in breast tumors and three out of six cell lines including MDA-MB-468, T47D and SKBR3. Not significant expression of TAF7L was evident in breast tumors but significant increase was noted in three out of six cell lines including MDA-MB-231, BT474 and T47D. OIP5 has ssignificant role in chromatin organization and cell cycle control during cell cycle exit and normal chromosome segregation during mitosis and TAF7L is a component of the transcription factor IID, which is involved in transcription initiation of most protein coding genes. TAF7Lis located at X chromosome and belongs to the CT-X gene family of cancer/testis antigens which contains about 50% of CT antigens, including those which have been used in cancer immunotherapy.

Characteristics and Preparation of Manganese Oxide Electrode by Using Pulse Voltammetry Electrodeposition for Electrolysis (펄스 전착법을 이용한 전기분해용 망간 산화물 전극의 제조 및 특성)

  • Yang, Jeong-Jin;Lee, Mi-Young;Kim, Jeong-Sik;Shin, Hyun-Soo;Park, Soo-Gil
    • Journal of the Korean Electrochemical Society
    • /
    • v.13 no.2
    • /
    • pp.138-144
    • /
    • 2010
  • In order to investigate the electrochemical propertied of titanium electrode for electrolysis, manganese oxide was electrodeposited on surface of mesh titanium by pulse voltammetry. The morphological changes and impedance results of manganese oxide electrodeposited electrode were analyzed by SEM and EDX. The size of electrodeposited manganese oxide on mesh titanium was increased with first cycle pulse time increase, and approximately 100 non-uniform manganese oxide was grown at 10 ms pulse polarization time. Charge transfer resistance($R_{ct}$) of near the overpotential was analyzed by EIS measurement and the feasibility of prepared electrode was evaluated by the overpotential calculated from Tafel plots.

Effects of Dexamethasone on the Burden of Marine Birnavirus (MABV) in Olive Flounder, Paralichthys olivaceus (Dexamethasone 투여가 넙치(Paralichthys olivaceus)의 marine birnavirus (MABV) 감염강도에 미치는 영향)

  • Kwon, Se Ryun;Nam, Yoon Kwon
    • Korean Journal of Ichthyology
    • /
    • v.19 no.2
    • /
    • pp.88-92
    • /
    • 2007
  • The effect of dexamethasone injection on the burden of marine birnavirus (MABV) in asymptomatically infected olive flounder (Paralichthys olivaceus) fingerlings was investigated. In real time PCR analysis, the threshold cycle (Ct) value of the fish injected with dexamethasone was significantly lower than that of the fish in the PBS-injected and no-handling groups. The higher amplification of the MABV gene in the dexamethasone-injected group than the 2 control groups was confirmed also by semi-quantitative RT-PCR. The results indicate an increase of MABV burden in olive flounder fingerlings after a single injection with dexamethasone.

CHAOS IN PRODUCTION PLANNING

  • Haghighirad, Farzad;Makui, Ahmad;Ashtiani, Behzad
    • Journal of applied mathematics & informatics
    • /
    • v.26 no.3_4
    • /
    • pp.739-750
    • /
    • 2008
  • A phenomenon which is seen in some of the manufacturing systems and production planning is chaos and the butterfly effect. The butterfly effect points out that in case of the presence of nonlinear relations in system and incorrect estimation of initial values of variables, the error in the estimates of system state will be intensified, and after a while there will be a large distance between available state of system and reality. Using mathematical means and computer simulation, we have tried to demonstrate that in a production system the numerical combination of Cycle Time (CT), Adjustment Time between existing and desired Work In Progress (WIP), and Adjustment Time between current and desired inventory can lead to chaos and butterfly effect in the behavior of the inventory state variable. Our paper concludes with a discussion of a hypothesis that emerged from this research.

  • PDF