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Effects of Dexamethasone on the Burden of Marine Birnavirus (MABV) in Olive Flounder, Paralichthys olivaceus  

Kwon, Se Ryun (Department of Aquatic Life Medicine, Pukyong National University)
Nam, Yoon Kwon (Department of Aquaculture, Pukyong National University)
Publication Information
Korean Journal of Ichthyology / v.19, no.2, 2007 , pp. 88-92 More about this Journal
Abstract
The effect of dexamethasone injection on the burden of marine birnavirus (MABV) in asymptomatically infected olive flounder (Paralichthys olivaceus) fingerlings was investigated. In real time PCR analysis, the threshold cycle (Ct) value of the fish injected with dexamethasone was significantly lower than that of the fish in the PBS-injected and no-handling groups. The higher amplification of the MABV gene in the dexamethasone-injected group than the 2 control groups was confirmed also by semi-quantitative RT-PCR. The results indicate an increase of MABV burden in olive flounder fingerlings after a single injection with dexamethasone.
Keywords
marine birnavirus; dexamethasone; viral titer; olive flounder;
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